ZA867375B - N-substituted diphenylpiperidines - Google Patents

N-substituted diphenylpiperidines

Info

Publication number
ZA867375B
ZA867375B ZA867375A ZA867375A ZA867375B ZA 867375 B ZA867375 B ZA 867375B ZA 867375 A ZA867375 A ZA 867375A ZA 867375 A ZA867375 A ZA 867375A ZA 867375 B ZA867375 B ZA 867375B
Authority
ZA
South Africa
Prior art keywords
diphenylpiperidines
substituted
substituted diphenylpiperidines
Prior art date
Application number
ZA867375A
Other languages
English (en)
Inventor
John Guilfoyle Mullin Jr
Richard Wightman Kierstead
Joseph Triscari
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA867375B publication Critical patent/ZA867375B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA867375A 1985-10-07 1986-09-26 N-substituted diphenylpiperidines ZA867375B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/785,113 US4632925A (en) 1985-10-07 1985-10-07 N-substituted diphenylpiperidines and antiobesity use thereof

Publications (1)

Publication Number Publication Date
ZA867375B true ZA867375B (en) 1987-05-27

Family

ID=25134481

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA867375A ZA867375B (en) 1985-10-07 1986-09-26 N-substituted diphenylpiperidines

Country Status (23)

Country Link
US (1) US4632925A (hu)
EP (1) EP0221376B1 (hu)
JP (1) JPH0633254B2 (hu)
KR (1) KR870003984A (hu)
AR (1) AR241422A1 (hu)
AT (1) ATE53997T1 (hu)
AU (1) AU593844B2 (hu)
CA (1) CA1281326C (hu)
DE (1) DE3672134D1 (hu)
DK (1) DK168291B1 (hu)
ES (1) ES2005074A6 (hu)
FI (1) FI85020C (hu)
GR (1) GR862513B (hu)
HU (1) HU196200B (hu)
IE (1) IE59434B1 (hu)
IL (1) IL80232A0 (hu)
MC (1) MC1769A1 (hu)
NO (1) NO166127C (hu)
NZ (1) NZ217798A (hu)
PH (1) PH24167A (hu)
PT (1) PT83495B (hu)
SG (1) SG17593G (hu)
ZA (1) ZA867375B (hu)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78939A (en) * 1986-01-17 1990-04-29 Robins Co Inc A H Pharmaceutical compositions containing n-substituted arylalkyl-and arylalkylene-piperidines and tetrahydropyridines and certain such novel compounds
GB9000305D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Anticholinergic agents
DE69109871T2 (de) * 1990-10-10 1995-09-14 Schering Corp., Kenilworth, N.J. Pyridin- und pyridin-n-oxid-derivate von diarylmethyl- piperidinen oder piperazinen, deren zusammensetzungen und anwendung.
CA2132848A1 (en) * 1992-03-27 1993-10-14 Richard Friary Unabridged bis-aryl carbinol derivatives, compositions and methods of use
US6030987A (en) * 1996-05-17 2000-02-29 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
US6184234B1 (en) * 1994-03-01 2001-02-06 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
US6017931A (en) * 1994-03-01 2000-01-25 Fmc Corporation Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US5639763A (en) * 1994-03-01 1997-06-17 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
BR9608794A (pt) * 1995-05-19 1999-02-17 Fmc Corp Composto composição contendo uma quantidade inseticidamente eficaz do composto e processo para controlar insetos
US6407116B1 (en) 1997-09-16 2002-06-18 Takeda Chemical Industries, Inc. Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs
US20100064413A1 (en) * 2008-03-14 2010-03-18 Simply Weights, LLC Exercise clothing and accessories
WO2009132979A1 (en) 2008-04-29 2009-11-05 F. Hoffmann-La Roche Ag 4-trimethylammonio-butyrates as cpt2 inhibitors
CN101952243B (zh) * 2008-04-29 2014-07-16 霍夫曼-拉罗奇有限公司 4-二甲氨基丁酸衍生物
WO2019134985A1 (en) 2018-01-08 2019-07-11 F. Hoffmann-La Roche Ag Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors
AU2021338497A1 (en) * 2020-09-03 2023-02-09 F. Hoffmann-La Roche Ag Heterocyclic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076717A (en) * 1971-12-15 1978-02-28 G. D. Searle & Co. Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
US3931197A (en) * 1974-02-08 1976-01-06 Richardson-Merrell Inc. Substituted piperidine derivatives
US4650874A (en) * 1984-11-26 1987-03-17 G. D. Searle & Co. N-(aralkoxybenzyl)-4(benzhydryl) piperidines

Also Published As

Publication number Publication date
KR870003984A (ko) 1987-05-06
EP0221376B1 (de) 1990-06-20
DK475286D0 (da) 1986-10-03
NO166127C (no) 1991-06-05
GR862513B (en) 1987-02-09
AR241422A1 (es) 1992-07-31
AU593844B2 (en) 1990-02-22
HUT41768A (en) 1987-05-28
FI85020C (fi) 1992-02-25
EP0221376A2 (de) 1987-05-13
PH24167A (en) 1990-03-22
JPS6287585A (ja) 1987-04-22
NO863978D0 (no) 1986-10-06
CA1281326C (en) 1991-03-12
AU6350186A (en) 1987-04-09
NO166127B (no) 1991-02-25
ES2005074A6 (es) 1989-03-01
HU196200B (en) 1988-10-28
IE862636L (en) 1987-04-07
NO863978L (no) 1987-04-08
DK168291B1 (da) 1994-03-07
DK475286A (da) 1987-04-08
SG17593G (en) 1993-05-21
DE3672134D1 (de) 1990-07-26
MC1769A1 (fr) 1987-07-17
FI864051A (fi) 1987-04-08
US4632925A (en) 1986-12-30
EP0221376A3 (en) 1987-09-02
PT83495B (pt) 1989-05-31
PT83495A (en) 1986-11-01
IE59434B1 (en) 1994-02-23
IL80232A0 (en) 1987-01-30
JPH0633254B2 (ja) 1994-05-02
NZ217798A (en) 1989-10-27
FI85020B (fi) 1991-11-15
FI864051A0 (fi) 1986-10-07
ATE53997T1 (de) 1990-07-15

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