FI864051A - N-substituerade difenylpiperidiner. - Google Patents

N-substituerade difenylpiperidiner. Download PDF

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Publication number
FI864051A
FI864051A FI864051A FI864051A FI864051A FI 864051 A FI864051 A FI 864051A FI 864051 A FI864051 A FI 864051A FI 864051 A FI864051 A FI 864051A FI 864051 A FI864051 A FI 864051A
Authority
FI
Finland
Prior art keywords
diphenylpiperidiner
substituerade
substituerade diphenylpiperidiner
Prior art date
Application number
FI864051A
Other languages
English (en)
Other versions
FI864051A0 (fi
FI85020B (fi
FI85020C (fi
Inventor
Jr John Guilfoyle Mullin
Richard Wightman Kierstead
Joseph Triscari
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI864051A0 publication Critical patent/FI864051A0/fi
Publication of FI864051A publication Critical patent/FI864051A/fi
Publication of FI85020B publication Critical patent/FI85020B/fi
Application granted granted Critical
Publication of FI85020C publication Critical patent/FI85020C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI864051A 1985-10-07 1986-10-07 Foerfarande foer framstaellning av terapeutiskt aktiva n-substituerade difenylpiperidiner. FI85020C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/785,113 US4632925A (en) 1985-10-07 1985-10-07 N-substituted diphenylpiperidines and antiobesity use thereof
US78511385 1985-10-07

Publications (4)

Publication Number Publication Date
FI864051A0 FI864051A0 (fi) 1986-10-07
FI864051A true FI864051A (fi) 1987-04-08
FI85020B FI85020B (fi) 1991-11-15
FI85020C FI85020C (fi) 1992-02-25

Family

ID=25134481

Family Applications (1)

Application Number Title Priority Date Filing Date
FI864051A FI85020C (fi) 1985-10-07 1986-10-07 Foerfarande foer framstaellning av terapeutiskt aktiva n-substituerade difenylpiperidiner.

Country Status (23)

Country Link
US (1) US4632925A (fi)
EP (1) EP0221376B1 (fi)
JP (1) JPH0633254B2 (fi)
KR (1) KR870003984A (fi)
AR (1) AR241422A1 (fi)
AT (1) ATE53997T1 (fi)
AU (1) AU593844B2 (fi)
CA (1) CA1281326C (fi)
DE (1) DE3672134D1 (fi)
DK (1) DK168291B1 (fi)
ES (1) ES2005074A6 (fi)
FI (1) FI85020C (fi)
GR (1) GR862513B (fi)
HU (1) HU196200B (fi)
IE (1) IE59434B1 (fi)
IL (1) IL80232A0 (fi)
MC (1) MC1769A1 (fi)
NO (1) NO166127C (fi)
NZ (1) NZ217798A (fi)
PH (1) PH24167A (fi)
PT (1) PT83495B (fi)
SG (1) SG17593G (fi)
ZA (1) ZA867375B (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78939A (en) * 1986-01-17 1990-04-29 Robins Co Inc A H Pharmaceutical compositions containing n-substituted arylalkyl-and arylalkylene-piperidines and tetrahydropyridines and certain such novel compounds
GB9000305D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Anticholinergic agents
EP0553191B1 (en) * 1990-10-10 1995-05-17 Schering Corporation Pyridine and pyridine n-oxide derivatives of diarylmethyl- piperidines or piperazines, compositions and use thereof
DK0635012T3 (da) * 1992-03-27 1996-08-19 Schering Corp Bis-aryl-carbinolderivater uden broer, præparater indeholdende disse og fremgangsmåder til anvendelse af disse
US5639763A (en) * 1994-03-01 1997-06-17 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US6017931A (en) * 1994-03-01 2000-01-25 Fmc Corporation Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US6184234B1 (en) * 1994-03-01 2001-02-06 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
US6030987A (en) * 1996-05-17 2000-02-29 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
WO1996036228A1 (en) * 1995-05-19 1996-11-21 Fmc Corporation Insecticidal n-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
AU9002598A (en) 1997-09-16 1999-04-05 Takeda Chemical Industries Ltd. Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs
US20100064413A1 (en) * 2008-03-14 2010-03-18 Simply Weights, LLC Exercise clothing and accessories
CN102015626B (zh) 2008-04-29 2013-12-11 霍夫曼-拉罗奇有限公司 作为cpt2抑制剂的4-三甲基铵基丁酸盐类
AU2009242240B2 (en) 2008-04-29 2011-09-22 F. Hoffmann-La Roche Ag 4-dimethylaminobutyric acid derivatives
WO2019134985A1 (en) 2018-01-08 2019-07-11 F. Hoffmann-La Roche Ag Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors
CN115989228A (zh) 2020-09-03 2023-04-18 豪夫迈·罗氏有限公司 杂环化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076717A (en) * 1971-12-15 1978-02-28 G. D. Searle & Co. Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
US3931197A (en) * 1974-02-08 1976-01-06 Richardson-Merrell Inc. Substituted piperidine derivatives
US4650874A (en) * 1984-11-26 1987-03-17 G. D. Searle & Co. N-(aralkoxybenzyl)-4(benzhydryl) piperidines

Also Published As

Publication number Publication date
SG17593G (en) 1993-05-21
NO863978L (no) 1987-04-08
PT83495A (en) 1986-11-01
NO166127B (no) 1991-02-25
CA1281326C (en) 1991-03-12
HU196200B (en) 1988-10-28
FI864051A0 (fi) 1986-10-07
DK475286D0 (da) 1986-10-03
PT83495B (pt) 1989-05-31
DK475286A (da) 1987-04-08
NO166127C (no) 1991-06-05
NZ217798A (en) 1989-10-27
IL80232A0 (en) 1987-01-30
FI85020B (fi) 1991-11-15
IE59434B1 (en) 1994-02-23
DK168291B1 (da) 1994-03-07
US4632925A (en) 1986-12-30
AU6350186A (en) 1987-04-09
IE862636L (en) 1987-04-07
NO863978D0 (no) 1986-10-06
GR862513B (en) 1987-02-09
HUT41768A (en) 1987-05-28
JPH0633254B2 (ja) 1994-05-02
AU593844B2 (en) 1990-02-22
EP0221376B1 (de) 1990-06-20
ATE53997T1 (de) 1990-07-15
PH24167A (en) 1990-03-22
AR241422A1 (es) 1992-07-31
ES2005074A6 (es) 1989-03-01
EP0221376A3 (en) 1987-09-02
JPS6287585A (ja) 1987-04-22
FI85020C (fi) 1992-02-25
DE3672134D1 (de) 1990-07-26
EP0221376A2 (de) 1987-05-13
ZA867375B (en) 1987-05-27
KR870003984A (ko) 1987-05-06
MC1769A1 (fr) 1987-07-17

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG