DK167900B1 - Middel til behandling og forebyggelse af haemostatiske forstyrrelser indeholdende vaevsprotein pp4 - Google Patents

Middel til behandling og forebyggelse af haemostatiske forstyrrelser indeholdende vaevsprotein pp4 Download PDF

Info

Publication number
DK167900B1
DK167900B1 DK665787A DK665787A DK167900B1 DK 167900 B1 DK167900 B1 DK 167900B1 DK 665787 A DK665787 A DK 665787A DK 665787 A DK665787 A DK 665787A DK 167900 B1 DK167900 B1 DK 167900B1
Authority
DK
Denmark
Prior art keywords
solution
liter
mmol
treatment
prevention
Prior art date
Application number
DK665787A
Other languages
Danish (da)
English (en)
Other versions
DK665787D0 (da
DK665787A (da
Inventor
Hartmut Loebermann
Christiane Bornmann
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of DK665787D0 publication Critical patent/DK665787D0/da
Publication of DK665787A publication Critical patent/DK665787A/da
Application granted granted Critical
Publication of DK167900B1 publication Critical patent/DK167900B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4721—Lipocortins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Dental Preparations (AREA)
DK665787A 1986-12-18 1987-12-17 Middel til behandling og forebyggelse af haemostatiske forstyrrelser indeholdende vaevsprotein pp4 DK167900B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3643182 1986-12-18
DE19863643182 DE3643182A1 (de) 1986-12-18 1986-12-18 Arzneimittel enthaltend das gewebeprotein pp4, verfahren zur herstellung von pp4 und zu seiner pasteurisierung sowie die verwendung von pp4

Publications (3)

Publication Number Publication Date
DK665787D0 DK665787D0 (da) 1987-12-17
DK665787A DK665787A (da) 1988-06-19
DK167900B1 true DK167900B1 (da) 1994-01-03

Family

ID=6316431

Family Applications (3)

Application Number Title Priority Date Filing Date
DK665787A DK167900B1 (da) 1986-12-18 1987-12-17 Middel til behandling og forebyggelse af haemostatiske forstyrrelser indeholdende vaevsprotein pp4
DK93359A DK35993D0 (da) 1986-12-18 1993-03-26 Fremgangsmaade til rensning af vaevsprotein pp4
DK93360A DK36093D0 (da) 1986-12-18 1993-03-26 Fremgangsmaade til pasteurisering af vaevsprotein pp4

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK93359A DK35993D0 (da) 1986-12-18 1993-03-26 Fremgangsmaade til rensning af vaevsprotein pp4
DK93360A DK36093D0 (da) 1986-12-18 1993-03-26 Fremgangsmaade til pasteurisering af vaevsprotein pp4

Country Status (13)

Country Link
US (1) US5097019A (ja)
EP (3) EP0457371A1 (ja)
JP (1) JP2532535B2 (ja)
KR (1) KR960007922B1 (ja)
AT (2) ATE121940T1 (ja)
AU (1) AU622102B2 (ja)
CA (1) CA1338395C (ja)
DE (3) DE3643182A1 (ja)
DK (3) DK167900B1 (ja)
ES (2) ES2072490T3 (ja)
FI (1) FI91218C (ja)
GR (1) GR3005247T3 (ja)
PT (1) PT86393B (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416151B (sv) * 1978-10-03 1980-12-01 Ake Gunnar Bolmgren Byggelement jemte mursten for tillverkning av elementet
DE3737239A1 (de) * 1987-11-03 1989-10-12 Behringwerke Ag Gentechnische herstellung von anticoagulatorischem protein pp4
NZ232813A (en) * 1989-03-10 1992-08-26 Snow Brand Milk Products Co Ltd Human fibroblast glycoprotein, cell differentiation, blood vessel endothelial cell growth factor, cellular immunology inforcing factor of 78 or 74 thousand daltons plus or minus two thousand daltons
DE3939346A1 (de) * 1989-11-29 1991-06-06 Behringwerke Ag Arzneimitel zur subkutanen oder intramuskulaeren applikation enthaltend polypeptide
DE4003773A1 (de) * 1990-02-08 1991-08-14 Behringwerke Ag Verfahren zur reinigung von lipocortinen
US20030220233A1 (en) 1994-01-24 2003-11-27 Neorx Corporation Radiolabeled annexins
US5968477A (en) 1994-01-24 1999-10-19 Neorx Corporation Radiolabeled annexin conjugates with hexose and a chelator
JP2747979B2 (ja) * 1994-08-19 1998-05-06 雪印乳業株式会社 ヒト由来の糖蛋白質からなる生理活性因子を有効成分とする医薬
DE19734648A1 (de) 1997-08-11 1999-02-18 Dade Behring Marburg Gmbh Verwendung von Annexinen als Lupus Antikoagulans Kontrolle oder Standard in Gerinnungstesten
US7635676B2 (en) * 2001-02-21 2009-12-22 Alavita Pharmaccuticals, Inc. Modified annexin proteins and methods for their use in organ transplantation
US20090291086A1 (en) * 2001-02-21 2009-11-26 Alavita Pharmaceuticals, Inc. Compositions and Methods for Treating Cerebral Thrombosis and Global Cerebral Ischemia
US7645739B2 (en) * 2001-02-21 2010-01-12 Alavita Pharmaceuticals, Inc. Modified annexin compositions and methods of using same
EP1839670A3 (en) * 2001-02-21 2009-11-11 Alavita Pharmaceuticals, Inc. Modified Annexin Proteins and their use against thrombosis
US7635680B2 (en) * 2001-02-21 2009-12-22 Alavita Pharmaceuticals, Inc. Attenuation of reperfusion injury
US6982154B2 (en) * 2002-02-21 2006-01-03 Surromed, Inc. Modified annexin proteins and methods for treating vaso-occlusive sickle-cell disease
GB2542391A (en) 2015-09-17 2017-03-22 Annexin Pharmaceuticals Ab Process of manufacture

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4461833A (en) * 1982-06-23 1984-07-24 University Patents, Inc. Chromatographically purifying proteolytic procoagulant enzyme from animal tissue extract
DE3237512A1 (de) * 1982-10-09 1984-04-12 Behringwerke Ag, 3550 Marburg Verfahren zur pasteurisierung von antihaemophilem kryopraezipitat (ahk) und danach hergestelltes antihaemophiles kryopraezipitat
DE3315000A1 (de) * 1983-04-26 1984-10-31 Behringwerke Ag, 3550 Marburg Gewebeprotein pp(pfeil abwaerts)4(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung
CA1265446A (en) * 1985-09-30 1990-02-06 Masahiro Maki Anticoagulating substance, process for preparing same and anticoagulant comprising same as an effective component
DE3724726A1 (de) * 1987-07-25 1989-02-02 Behringwerke Ag Verfahren zur reinigung des plazentaren gewebeproteins pp4
US4896172A (en) * 1987-11-20 1990-01-23 Canon Kabushiki Kaisha Liquid injection recording apparatus including recording liquid circulation control

Also Published As

Publication number Publication date
DK35993A (da) 1993-03-26
CA1338395C (en) 1996-06-11
FI91218B (fi) 1994-02-28
EP0271885A3 (en) 1988-09-21
ES2072490T3 (es) 1995-07-16
EP0271885B1 (de) 1992-05-06
ATE121940T1 (de) 1995-05-15
EP0271885A2 (de) 1988-06-22
KR960007922B1 (ko) 1996-06-17
PT86393A (en) 1988-01-01
ATE75618T1 (de) 1992-05-15
AU8264687A (en) 1988-06-23
FI875518A (fi) 1988-06-19
DE3751281D1 (de) 1995-06-08
DK36093A (da) 1993-03-26
JP2532535B2 (ja) 1996-09-11
FI91218C (fi) 1994-06-10
EP0457370B1 (de) 1995-05-03
GR3005247T3 (ja) 1993-05-24
EP0457370A1 (de) 1991-11-21
ES2042532T3 (es) 1993-12-16
DK665787D0 (da) 1987-12-17
DK665787A (da) 1988-06-19
EP0457371A1 (de) 1991-11-21
FI875518A0 (fi) 1987-12-16
KR880007088A (ko) 1988-08-26
DE3643182A1 (de) 1988-06-30
US5097019A (en) 1992-03-17
DE3778852D1 (de) 1992-06-11
AU622102B2 (en) 1992-04-02
PT86393B (pt) 1990-11-20
DK35993D0 (da) 1993-03-26
JPS63165328A (ja) 1988-07-08
DK36093D0 (da) 1993-03-26

Similar Documents

Publication Publication Date Title
DK167900B1 (da) Middel til behandling og forebyggelse af haemostatiske forstyrrelser indeholdende vaevsprotein pp4
US5099003A (en) Method of preparing a sterile plasma-protein solution containing fibrinogen and factor xiii
DK155568B (da) Fremgangsmaade til stabilisering af koagulationsfaktorerne ii, viii, xiii og antithrombin iii samt plasminogen, og saaledes at disse er fibrinogen-fri og fri for risiko for en hepatitis-overfoering
US5854403A (en) Method for isolation of highly pure von Willebrand Factor
US4446134A (en) Process for heat treatment of aqueous solution containing human blood coagulation factor VIII
EP0037078B1 (en) Process for heat treatment of aqueous solution containing human blood coagulation factor xiii
US5151499A (en) Production method for protein-containing composition
JPS597693B2 (ja) 抗トロンビン製剤及びその製法
JPS62174023A (ja) 抗血液凝固物質、その製法及びそれを有効成分とする抗血液凝固剤
DK174066B1 (da) Fremgangsmåde til fremstilling af et faktor VIII-præparat
DK163107B (da) Fremgangsmaade til fremstilling af et koncentrat af antihaemofilisk faktor med hoej renhed
US4749783A (en) Viral inactivation and purification of active proteins
US4562072A (en) Process for the pasteurization of antihemophilic cryoprecipitate (AHC) and antihemophilic cryoprecipitate prepared thereby
CA1196281A (en) Heat stabilization of plasma proteins
US20030129167A1 (en) Enhanced production of blood components, blood cells and plasma without freezing
NO138145B (no) Fremgangsmaate for fremstilling av et enzympreparat
US4115551A (en) Compounds of the plasminogen type and method for obtaining such compounds from placental pulps
JPH06505494A (ja) Ｉｘ因子の調製
JP3558292B2 (ja) 血小板付着インヒビター
JPS61189228A (ja) 血液凝固第８因子製剤の製法
CA1297634C (en) Anticoagulating substance and preparation process thereof
JP2001000179A (ja) ウィルスの不活化方法
MXPA03007069A (es) Acido carboxilico tal como acido citrico para desinfectar o mejorar la produccion de productos sanguineos tales como el plasma, crioprecipitado y/o plaqueta.
NO175622B (ja)
JPH04502324A (ja) 純粋なｉ因子蛋白質および該蛋白質の製造方法

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed