DK166381C - Analogifremgangsmaade til fremstilling af (3-aminopropoxy)-bibenzylderivater og farmaceutisk acceptable salte deraf - Google Patents
Analogifremgangsmaade til fremstilling af (3-aminopropoxy)-bibenzylderivater og farmaceutisk acceptable salte derafInfo
- Publication number
- DK166381C DK166381C DK365682A DK365682A DK166381C DK 166381 C DK166381 C DK 166381C DK 365682 A DK365682 A DK 365682A DK 365682 A DK365682 A DK 365682A DK 166381 C DK166381 C DK 166381C
- Authority
- DK
- Denmark
- Prior art keywords
- aminopropoxy
- analogue
- preparation
- acceptable salts
- pharmaceutical acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56130704A JPS5832847A (ja) | 1981-08-20 | 1981-08-20 | (3−アミノプロポキシ)ビベンジル類 |
JP13070481 | 1981-08-20 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK365682A DK365682A (da) | 1983-02-21 |
DK166381B DK166381B (da) | 1993-05-10 |
DK166381C true DK166381C (da) | 1993-09-27 |
Family
ID=15040620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK365682A DK166381C (da) | 1981-08-20 | 1982-08-13 | Analogifremgangsmaade til fremstilling af (3-aminopropoxy)-bibenzylderivater og farmaceutisk acceptable salte deraf |
Country Status (9)
Country | Link |
---|---|
US (2) | US4485258A (de) |
EP (1) | EP0072942B1 (de) |
JP (1) | JPS5832847A (de) |
CA (1) | CA1193264A (de) |
DD (1) | DD202531A5 (de) |
DE (1) | DE3275540D1 (de) |
DK (1) | DK166381C (de) |
HU (1) | HU186560B (de) |
NO (1) | NO156525C (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5832847A (ja) * | 1981-08-20 | 1983-02-25 | Mitsubishi Chem Ind Ltd | (3−アミノプロポキシ)ビベンジル類 |
US4616017A (en) * | 1984-06-04 | 1986-10-07 | Merck & Co., Inc. | Aminohydroxypropoxy substituted aryl compounds |
JPH02304022A (ja) * | 1989-05-18 | 1990-12-17 | Mitsubishi Kasei Corp | セロトニン拮抗剤 |
HUT70031A (en) * | 1992-11-30 | 1995-09-28 | Sankyo Co | Alfa, omega-diarylalkane derivatives, their preparation and pharmaceutical compositions containing them |
JP4063341B2 (ja) * | 1994-07-06 | 2008-03-19 | メイ株式会社 | 緑内障治療剤及び眼圧降下剤 |
EP0813878B1 (de) * | 1996-06-17 | 2002-02-06 | Mitsubishi Chemical Corporation | Mittel zur Beschleunigung des Tränenflusses enthaltend einen Serotonin-Liganden, insbesondere Aminoalkoxybibenzyle |
AU6367399A (en) | 1998-11-02 | 2000-05-22 | Welfide Corporation | Pyrrolidine compounds and medicinal utilization thereof |
EP1430890A4 (de) * | 2001-09-26 | 2007-01-17 | Mitsubishi Pharma Corp | Thrombus/thrombogenese-hemmer |
CN1824647B (zh) * | 2005-02-22 | 2011-04-20 | 田边三菱制药株式会社 | (±)2-(二甲基氨基)-1-{[O-(m-甲氧基苯乙基)苯氧基]甲基}乙基氢琥珀酸酯盐酸盐的晶体 |
KR101393178B1 (ko) * | 2005-02-22 | 2014-05-08 | 미쓰비시 타나베 파마 코퍼레이션 | (±)2-(디메틸아미노)-1-{[O-(m-메톡시페네틸)페녹시]메틸}에틸 수소 숙시네이트 염산염의 결정 |
JP2006160764A (ja) * | 2005-02-22 | 2006-06-22 | Mitsubishi Pharma Corp | (±)2−(ジメチルアミノ)−1−{〔O−(m−メトキシフェネチル)フェノキシ〕メチル}エチル水素サクシナート塩酸塩の結晶 |
US8123513B2 (en) | 2005-06-03 | 2012-02-28 | Rheon Automatic Machinery Co., Ltd. | Apparatus for rolling food dough |
CN101239920B (zh) * | 2007-02-05 | 2013-05-22 | 南京康然医药科技有限公司 | 一种盐酸沙格雷酯的制备方法 |
JP5090770B2 (ja) * | 2007-04-06 | 2012-12-05 | ダイト株式会社 | 塩酸サルポグレラートの工業的製造方法 |
KR100881890B1 (ko) | 2007-05-03 | 2009-02-04 | 주식회사 엔지켐 | 사포그렐레이트 염산염의 제조방법 |
WO2009060952A1 (ja) * | 2007-11-09 | 2009-05-14 | Mitsubishi Tanabe Pharma Corporation | 新規製剤 |
JP5116025B2 (ja) | 2008-01-21 | 2013-01-09 | レオン自動機株式会社 | 食品生地延展成形装置および食品生地延展成形方法 |
KR20100050371A (ko) * | 2008-11-10 | 2010-05-13 | 주식회사 참조아 | 염산((±)-2-(디메칠아미노)-1-[[o-(m-메톡시펜에틸)페녹시]메틸]에틸하이드로겐 숙시네이트의 신규 결정 및 이 신규결정을 유효성분으로 함유하는 의약조성물 |
KR100911720B1 (ko) | 2009-04-10 | 2009-08-10 | 주식회사 한서켐 | 결정형 염산 사포그릴레이트의 제조방법 |
KR101653816B1 (ko) | 2014-06-25 | 2016-09-06 | 주식회사 대희화학 | 결정형 사포그릴레이트 옥살산염 일수화물 또는 이의 무수물 |
CN105237411A (zh) * | 2014-09-23 | 2016-01-13 | 山东齐都药业有限公司 | 一种盐酸沙格雷酯光降解杂质iii的制备方法 |
KR101905865B1 (ko) | 2017-04-11 | 2018-10-08 | 아주대학교산학협력단 | 사포그릴레이트를 유효성분으로 포함하는 감각신경성 난청의 예방 또는 치료용 조성물 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL301580A (de) * | 1962-12-11 | |||
DE2001431C3 (de) * | 1970-01-06 | 1974-12-12 | Helopharm W. Petrik & Co Kg, 1000 Berlin | 2-(2'-Hydroxy-3'-alkylaminopropoxy)-Omega-phenyl-propiophenone und Verfahren zur Herstellung derselben |
SE386892B (sv) * | 1972-07-06 | 1976-08-23 | Haessle Ab | Forfarande for framstellning av oxaminoforeningar |
GB1486001A (en) * | 1974-07-30 | 1977-09-14 | Beecham Group Ltd | 7-aminoalkoxy substituted benzopyrans benzo thiopyrans and naphthalenes |
GB1493998A (en) * | 1975-06-03 | 1977-12-07 | Beecham Group Ltd | Propanolamine derivatives |
US4071552A (en) * | 1976-05-19 | 1978-01-31 | Ayerst Mckenna And Harrison Ltd. | Aryloxy aminobutanols, their preparation and use thereof |
JPS5365836A (en) * | 1976-11-26 | 1978-06-12 | Teijin Ltd | Preparation of aminopropanol derivs. or their salts |
US4220603A (en) * | 1977-10-07 | 1980-09-02 | Mitsubishi Chemical Industries, Limited | Pharmaceutically active (omega-aminoalkoxy)bibenzyls |
JPS6045632B2 (ja) * | 1978-03-09 | 1985-10-11 | 三菱化学株式会社 | ω−アミノアルコキシスチルベン類及びその酸付加塩 |
JPS5531136A (en) * | 1978-08-25 | 1980-03-05 | Hitachi Metals Ltd | Fe-cr-co type magnet alloy |
JPS5629549A (en) * | 1979-08-18 | 1981-03-24 | Tsutomu Kunishige | Preparation of 1-aryloxy-3-isopropylaminopropan-2-ol |
JPS5629550A (en) * | 1979-08-18 | 1981-03-24 | Tsutomu Kunishige | Novel preparation of 1-aryloxy-3-isopropylaminopropan-2-ol |
JPS56123954A (en) * | 1980-03-05 | 1981-09-29 | Sagami Chem Res Center | Preparation of aminoalcohol derivative |
JPS5770844A (en) * | 1980-10-20 | 1982-05-01 | Paamakemu Asia:Kk | Preparation of aminopropanol derivative |
JPS5832847A (ja) * | 1981-08-20 | 1983-02-25 | Mitsubishi Chem Ind Ltd | (3−アミノプロポキシ)ビベンジル類 |
JPS6123954A (ja) * | 1984-07-12 | 1986-02-01 | Hitachi Ltd | Nmrイメ−ジング装置 |
-
1981
- 1981-08-20 JP JP56130704A patent/JPS5832847A/ja active Granted
-
1982
- 1982-07-29 US US06/403,119 patent/US4485258A/en not_active Expired - Lifetime
- 1982-08-04 DE DE8282107067T patent/DE3275540D1/de not_active Expired
- 1982-08-04 EP EP82107067A patent/EP0072942B1/de not_active Expired
- 1982-08-10 CA CA000409074A patent/CA1193264A/en not_active Expired
- 1982-08-13 DK DK365682A patent/DK166381C/da active
- 1982-08-17 HU HU822634A patent/HU186560B/hu unknown
- 1982-08-18 DD DD82242600A patent/DD202531A5/de not_active IP Right Cessation
- 1982-08-19 NO NO822833A patent/NO156525C/no not_active IP Right Cessation
-
1984
- 1984-07-09 US US06/629,061 patent/US4599419A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
HU186560B (en) | 1985-08-28 |
US4485258A (en) | 1984-11-27 |
DE3275540D1 (en) | 1987-04-09 |
DK365682A (da) | 1983-02-21 |
EP0072942A2 (de) | 1983-03-02 |
JPS6313427B2 (de) | 1988-03-25 |
US4599419A (en) | 1986-07-08 |
DD202531A5 (de) | 1983-09-21 |
EP0072942A3 (en) | 1984-06-06 |
NO822833L (no) | 1983-02-21 |
JPS5832847A (ja) | 1983-02-25 |
CA1193264A (en) | 1985-09-10 |
EP0072942B1 (de) | 1987-03-04 |
NO156525B (no) | 1987-06-29 |
DK166381B (da) | 1993-05-10 |
NO156525C (no) | 1987-10-07 |
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