DK164742C - Dna-sekvens, der koder for ifn-alfa2(arg), pbr322-plasmid indeholdende en saadan dna-sekvens, fremgangsmaade til fremstilling af en klon indeholdende naevnte plasmid, og tilsvarende mikroorganisme, samt fremgangsmaader til fremstilling af henholdsvis ifn-alfa2(arg), naevnte mikroorganisme og naevnte dna-sekvens - Google Patents
Dna-sekvens, der koder for ifn-alfa2(arg), pbr322-plasmid indeholdende en saadan dna-sekvens, fremgangsmaade til fremstilling af en klon indeholdende naevnte plasmid, og tilsvarende mikroorganisme, samt fremgangsmaader til fremstilling af henholdsvis ifn-alfa2(arg), naevnte mikroorganisme og naevnte dna-sekvensInfo
- Publication number
- DK164742C DK164742C DK239383A DK239383A DK164742C DK 164742 C DK164742 C DK 164742C DK 239383 A DK239383 A DK 239383A DK 239383 A DK239383 A DK 239383A DK 164742 C DK164742 C DK 164742C
- Authority
- DK
- Denmark
- Prior art keywords
- dna sequence
- plasmid
- microsmanism
- alfa2
- ifn
- Prior art date
Links
- 108091028043 Nucleic acid sequence Proteins 0.000 title 3
- 239000013612 plasmid Substances 0.000 title 2
- 244000005700 microbiome Species 0.000 title 1
- 108010047761 Interferon-alpha Proteins 0.000 abstract 3
- 102000006992 Interferon-alpha Human genes 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
- Y10S930/142—Interferon
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823220116 DE3220116A1 (de) | 1982-05-28 | 1982-05-28 | Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung |
| DE3220116 | 1982-05-28 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK239383D0 DK239383D0 (da) | 1983-05-27 |
| DK239383A DK239383A (da) | 1983-11-29 |
| DK164742B DK164742B (da) | 1992-08-10 |
| DK164742C true DK164742C (da) | 1992-12-28 |
Family
ID=6164725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK239383A DK164742C (da) | 1982-05-28 | 1983-05-27 | Dna-sekvens, der koder for ifn-alfa2(arg), pbr322-plasmid indeholdende en saadan dna-sekvens, fremgangsmaade til fremstilling af en klon indeholdende naevnte plasmid, og tilsvarende mikroorganisme, samt fremgangsmaader til fremstilling af henholdsvis ifn-alfa2(arg), naevnte mikroorganisme og naevnte dna-sekvens |
Country Status (22)
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3247922A1 (de) * | 1982-12-24 | 1984-06-28 | Boehringer Ingelheim International GmbH, 6507 Ingelheim | Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten |
| DE3515336C2 (de) * | 1985-04-27 | 1994-01-20 | Boehringer Ingelheim Int | Verfahren zur Herstellung und Reinigung von â-Interferon |
| US4709324A (en) * | 1985-11-27 | 1987-11-24 | Motorola, Inc. | Data processor control unit having an interrupt service using instruction prefetch redirection |
| CA2025180A1 (en) * | 1989-10-12 | 1991-04-13 | William G. Weisburg | Nucleic acid probes and methods for detecting pathogenic candida yeasts |
| US6685933B1 (en) | 1998-07-28 | 2004-02-03 | The United States Of America As Represented By The Department Of Health And Human Services | Interferon α hybrids |
| BR0115392A (pt) * | 2000-11-03 | 2004-06-15 | Biomedicines Inc | Método para o tratamento de uma doença sensìvel a interferona em um animal de sangue quente, método para individualizar as dosagens de uma interferona no tratamento, método para a fabricação de um dispositivo de liberação de efeito terapêutico de longa duração de uma droga ao longo de um perìodo de tempo, e conjunto útil para a ministração de uma quantidade relativamente constante de uma droga |
| FR2817559B1 (fr) * | 2000-12-06 | 2003-12-12 | Genodyssee | Procede de determination d'un ou plusieurs polymorphisme(s) fontionnel(s) dans la sequence nucleique d'un gene "candidat" fonctionnel preselectionne et ses applications |
| FR2821625B1 (fr) * | 2001-03-01 | 2003-05-16 | Genodyssee | Nouveaux polynucleotides comportant un polymorphisme de type snp fonctionnel dans la sequence nucleotidique du gene ifn-alpha-2 ainsi que de nouveaux polypeptides codes par ces polynucleotides et leurs utilisations therapeutiques |
| FR2823220B1 (fr) * | 2001-04-04 | 2003-12-12 | Genodyssee | Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo) |
| KR20040053291A (ko) * | 2001-11-09 | 2004-06-23 | 바이오메디신즈 인코포레이티드 | 오메가 인터페론을 이용한 질환 치료 방법 |
| US20040063912A1 (en) * | 2002-03-15 | 2004-04-01 | The Brigham And Women's Hospital, Inc. | Central airway administration for systemic delivery of therapeutics |
| WO2003099320A1 (en) | 2002-05-24 | 2003-12-04 | Zensun (Shanghai) Sci-Tech.Ltd | Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy |
| ATE466085T1 (de) * | 2002-09-09 | 2010-05-15 | Hanall Pharmaceutical Co Ltd | Protease-resistente modifizierte interferon alpha polypeptide |
| NZ586034A (en) * | 2004-02-02 | 2011-10-28 | Ambrx Inc | Modified human growth hormone polypeptides and their uses |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| ATE481963T1 (de) | 2006-05-30 | 2010-10-15 | Intarcia Therapeutics Inc | Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem |
| CA2670821C (en) | 2006-08-09 | 2012-05-15 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
| US20080260820A1 (en) * | 2007-04-19 | 2008-10-23 | Gilles Borrelly | Oral dosage formulations of protease-resistant polypeptides |
| WO2008133908A2 (en) | 2007-04-23 | 2008-11-06 | Intarcia Therapeutics, Inc. | Suspension formulations of insulinotropic peptides and uses thereof |
| EP2240155B1 (en) | 2008-02-13 | 2012-06-06 | Intarcia Therapeutics, Inc | Devices, formulations, and methods for delivery of multiple beneficial agents |
| PL2462246T3 (pl) | 2009-09-28 | 2018-02-28 | Intarcia Therapeutics, Inc | Szybkie ustalenie i/lub zakończenie dostarczania leku zasadniczo w stanie równowagi dynamicznej |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| WO2013024156A2 (en) | 2011-08-17 | 2013-02-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection |
| WO2013024158A1 (en) | 2011-08-17 | 2013-02-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Combinations of protein kinase inhibitors and interferons or of protein kinase inhibitors and direct acting antivirals for the treatment and the prevention of hcv infection |
| WO2014033266A1 (en) | 2012-08-31 | 2014-03-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| MA44390A (fr) | 2015-06-03 | 2019-01-23 | Intarcia Therapeutics Inc | Systèmes de mise en place et de retrait d'implant |
| KR20240037175A (ko) | 2016-05-16 | 2024-03-21 | 인타르시아 세라퓨틱스 인코포레이티드 | 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법 |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| EP3565580B1 (en) | 2017-01-03 | 2024-03-06 | i2o Therapeutics, Inc. | Continuous administration of exenatide and co-adminstration of acetaminophen, ethinylestradiol or levonorgestrel |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2906160A1 (de) * | 1979-02-17 | 1980-09-04 | Thomae Gmbh Dr K | Verbessertes verfahren zur herstellung von humaninterferon |
| AU538665B2 (en) * | 1979-10-30 | 1984-08-23 | Juridical Foundation, Japanese Foundation For Cancer Research | Human interferon dna |
| IL58765A (en) * | 1979-11-21 | 1986-09-30 | Yeda Res & Dev | Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta |
| DK170236B1 (da) * | 1980-01-08 | 1995-07-10 | Biogen Inc | Rekombinante DNA-molekyler, fremgangsmåde til fremstilling af et polypeptid af IFN-alfa typen og fremgangsmåde til udvælgelse af DNA-sekvenser, der koder for polypeptider af IFN-alfa typen |
| US4530901A (en) * | 1980-01-08 | 1985-07-23 | Biogen N.V. | Recombinant DNA molecules and their use in producing human interferon-like polypeptides |
| GB2068970B (en) * | 1980-02-06 | 1983-06-22 | Searle & Co | Recombinant dna technique for the preparation of a protein resembling human interferon |
| DE3005843A1 (de) * | 1980-02-16 | 1981-09-10 | Hoechst Ag, 6000 Frankfurt | Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus |
| DE3005897A1 (de) * | 1980-02-16 | 1981-09-03 | Hoechst Ag, 6000 Frankfurt | Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus |
| ES506955A0 (es) * | 1980-11-10 | 1983-02-01 | Genentech Inc | Un procedimiento para producir un polipeptido antiviral. |
| DE3106982A1 (de) * | 1981-02-25 | 1982-09-09 | Dr. Karl Thomae Gmbh, 7950 Biberach | "neues tridecadeoxynukleotid, verfahren zu seiner herstellung und verwendung" |
| IL63327A (en) * | 1981-07-16 | 1985-11-29 | Yeda Res & Dev | Production of interferon beta1 and alpha-phage recombinants for its production in host bacteria |
| GB2108510B (en) | 1981-10-03 | 1984-12-12 | Ciba Geigy Ag | Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof |
-
1982
- 1982-05-28 DE DE19823220116 patent/DE3220116A1/de active Granted
-
1983
- 1983-05-19 US US06/495,944 patent/US4820638A/en not_active Expired - Fee Related
- 1983-05-23 FI FI831818A patent/FI82072C/fi not_active IP Right Cessation
- 1983-05-24 EP EP83105116A patent/EP0095702B1/de not_active Expired
- 1983-05-24 AT AT83105116T patent/ATE42114T1/de not_active IP Right Cessation
- 1983-05-24 GR GR71447A patent/GR79236B/el unknown
- 1983-05-24 DE DE8383105116T patent/DE3379591D1/de not_active Expired
- 1983-05-26 IL IL68790A patent/IL68790A/xx unknown
- 1983-05-26 DD DD83251287A patent/DD211359C4/de not_active IP Right Cessation
- 1983-05-27 ZA ZA833845A patent/ZA833845B/xx unknown
- 1983-05-27 DK DK239383A patent/DK164742C/da not_active IP Right Cessation
- 1983-05-27 NO NO831903A patent/NO168538C/no unknown
- 1983-05-27 AU AU15044/83A patent/AU565479B2/en not_active Ceased
- 1983-05-27 NZ NZ204384A patent/NZ204384A/en unknown
- 1983-05-27 UA UA3598429A patent/UA8037A1/uk unknown
- 1983-05-27 SU SU833598429A patent/SU1346048A3/ru active
- 1983-05-27 ES ES522762A patent/ES522762A0/es active Granted
- 1983-05-27 HU HU831890A patent/HU196452B/hu not_active IP Right Cessation
- 1983-05-27 JP JP58093886A patent/JPH0774238B2/ja not_active Expired - Lifetime
- 1983-05-28 KR KR1019830002362A patent/KR920006349B1/ko not_active Expired
-
1984
- 1984-02-01 ES ES529360A patent/ES529360A0/es active Granted
-
1992
- 1992-04-07 SG SG386/92A patent/SG38692G/en unknown
- 1992-06-12 MX MX9202815A patent/MX9202815A/es unknown
-
1993
- 1993-03-22 JP JP5062065A patent/JP2558422B2/ja not_active Expired - Lifetime
- 1993-10-21 HK HK1128/93A patent/HK112893A/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK164742C (da) | Dna-sekvens, der koder for ifn-alfa2(arg), pbr322-plasmid indeholdende en saadan dna-sekvens, fremgangsmaade til fremstilling af en klon indeholdende naevnte plasmid, og tilsvarende mikroorganisme, samt fremgangsmaader til fremstilling af henholdsvis ifn-alfa2(arg), naevnte mikroorganisme og naevnte dna-sekvens | |
| DK547185D0 (da) | Vektorer til ekspression af hirudin, transformerede celler og fremgangsmaade til fremstilling af hirudin | |
| ZA859437B (en) | Dna sequence encoding a hirudin-like protein and process for preparing such protein | |
| NO175640C (no) | Fusjonsproteiner og DNA som koder for disse | |
| SE8101005L (sv) | Mikrobiologiskt framstelld polypeptid med samma aminosyrasekvens som hos humant interferon, dna och plasmider, som koderar for denna sekvens, mikroorganismer, som innehaller dessa genetiska informationer och forfaran... | |
| ES2009906A6 (es) | Procedimiento de preparacion de transformantes bacterianos. | |
| DK645887A (da) | Gamma-hesteinterferon, fremgangsmaade til fremstilling af, samt anvendelse af en saadan forbindelse | |
| SE8101004L (sv) | Mikrobiologiskt framstelld polypeptid med samma aminosyrasekvens som hos humant interferon, dna och plasmider, som koderar for denna sekvens, mikroorganismer, som innehaller dessa genetiska informationer och forfarande | |
| ATE61631T1 (de) | Gen fuer ein protein mit insektizider wirkung. | |
| DK487787D0 (da) | Aminosyresekvens af l-phenylalaninammoniaklyase, dna-sekevens der koder for samme, rekombinant dna-plasmid og rekombinant mikroorganisme indeholdende dette samt fremgangsmaade til fremstilling af l-phenylalaninammoniaklyase ved dyrkning af denne organisme | |
| DK447083D0 (da) | Dna, som koder for humant interferon-gamma, rekombinant-dna, mikroorganisme indeholdende rekombinant-dna'en og fremgangsmade til fremstilling af humant interferon-gamma-polypeptid | |
| DE3751757D1 (de) | Autonom replizierende DNA Fragmente aus Säugerzellen mit Affinität zu DNA bindenden Proteinen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |