DK239383A - Mikrobiologisk fremstillede alfa- og beta-interferoner, dna-sekvenser, der koder for disse interferoner, mikroorganismer, som indeholder denne genetiske information, og fremgangsmaade til deres fremstilling - Google Patents

Mikrobiologisk fremstillede alfa- og beta-interferoner, dna-sekvenser, der koder for disse interferoner, mikroorganismer, som indeholder denne genetiske information, og fremgangsmaade til deres fremstilling Download PDF

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Publication number
DK239383A
DK239383A DK239383A DK239383A DK239383A DK 239383 A DK239383 A DK 239383A DK 239383 A DK239383 A DK 239383A DK 239383 A DK239383 A DK 239383A DK 239383 A DK239383 A DK 239383A
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DK
Denmark
Prior art keywords
interferones
microbiologically
alfa
interferons
beta
Prior art date
Application number
DK239383A
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English (en)
Other versions
DK164742B (da
DK239383D0 (da
DK164742C (da
Inventor
Eva Dworkin-Rastl
Marc-Bruce Dworkin
Guenther Adolf
Peter Meindl
Gerhard Bodo
Peter Swetly
Original Assignee
Thomae Gmbh Dr K
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Publication date
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Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
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Publication of DK239383A publication Critical patent/DK239383A/da
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/142—Interferon
DK239383A 1982-05-28 1983-05-27 Dna-sekvens, der koder for ifn-alfa2(arg), pbr322-plasmid indeholdende en saadan dna-sekvens, fremgangsmaade til fremstilling af en klon indeholdende naevnte plasmid, og tilsvarende mikroorganisme, samt fremgangsmaader til fremstilling af henholdsvis ifn-alfa2(arg), naevnte mikroorganisme og naevnte dna-sekvens DK164742C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823220116 DE3220116A1 (de) 1982-05-28 1982-05-28 Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung
DE3220116 1982-05-28

Publications (4)

Publication Number Publication Date
DK239383D0 DK239383D0 (da) 1983-05-27
DK239383A true DK239383A (da) 1983-11-29
DK164742B DK164742B (da) 1992-08-10
DK164742C DK164742C (da) 1992-12-28

Family

ID=6164725

Family Applications (1)

Application Number Title Priority Date Filing Date
DK239383A DK164742C (da) 1982-05-28 1983-05-27 Dna-sekvens, der koder for ifn-alfa2(arg), pbr322-plasmid indeholdende en saadan dna-sekvens, fremgangsmaade til fremstilling af en klon indeholdende naevnte plasmid, og tilsvarende mikroorganisme, samt fremgangsmaader til fremstilling af henholdsvis ifn-alfa2(arg), naevnte mikroorganisme og naevnte dna-sekvens

Country Status (22)

Country Link
US (1) US4820638A (da)
EP (1) EP0095702B1 (da)
JP (2) JPH0774238B2 (da)
KR (1) KR920006349B1 (da)
AT (1) ATE42114T1 (da)
AU (1) AU565479B2 (da)
DD (1) DD211359C4 (da)
DE (2) DE3220116A1 (da)
DK (1) DK164742C (da)
ES (2) ES8403522A1 (da)
FI (1) FI82072C (da)
GR (1) GR79236B (da)
HK (1) HK112893A (da)
HU (1) HU196452B (da)
IL (1) IL68790A (da)
MX (1) MX9202815A (da)
NO (1) NO168538C (da)
NZ (1) NZ204384A (da)
SG (1) SG38692G (da)
SU (1) SU1346048A3 (da)
UA (1) UA8037A1 (da)
ZA (1) ZA833845B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US4709324A (en) * 1985-11-27 1987-11-24 Motorola, Inc. Data processor control unit having an interrupt service using instruction prefetch redirection
CA2025180A1 (en) * 1989-10-12 1991-04-13 William G. Weisburg Nucleic acid probes and methods for detecting pathogenic candida yeasts
US6685933B1 (en) 1998-07-28 2004-02-03 The United States Of America As Represented By The Department Of Health And Human Services Interferon α hybrids
AU2587002A (en) * 2000-11-03 2002-05-15 Biomedicines Inc Method for short-term and long-term drug dosimetry
FR2817559B1 (fr) * 2000-12-06 2003-12-12 Genodyssee Procede de determination d'un ou plusieurs polymorphisme(s) fontionnel(s) dans la sequence nucleique d'un gene "candidat" fonctionnel preselectionne et ses applications
FR2821625B1 (fr) * 2001-03-01 2003-05-16 Genodyssee Nouveaux polynucleotides comportant un polymorphisme de type snp fonctionnel dans la sequence nucleotidique du gene ifn-alpha-2 ainsi que de nouveaux polypeptides codes par ces polynucleotides et leurs utilisations therapeutiques
FR2823220B1 (fr) * 2001-04-04 2003-12-12 Genodyssee Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)
ATE481135T1 (de) * 2001-11-09 2010-10-15 Intarcia Therapeutics Inc Kombinationstherapie mit omega-interferon zur behandlung von hepatitis c virus oder gelbfieber virus infektionen
US20040063912A1 (en) * 2002-03-15 2004-04-01 The Brigham And Women's Hospital, Inc. Central airway administration for systemic delivery of therapeutics
AU2002304965A1 (en) 2002-05-24 2003-12-12 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
WO2004022593A2 (en) * 2002-09-09 2004-03-18 Nautilus Biotech Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
NZ586034A (en) 2004-02-02 2011-10-28 Ambrx Inc Modified human growth hormone polypeptides and their uses
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
DK2020990T3 (da) 2006-05-30 2010-12-13 Intarcia Therapeutics Inc Strømningsmodulator med en indre kanal til et todelt osmotisk fremføringssystem
EP2049081B1 (en) 2006-08-09 2012-11-14 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
US20080260820A1 (en) * 2007-04-19 2008-10-23 Gilles Borrelly Oral dosage formulations of protease-resistant polypeptides
CN101715340A (zh) 2007-04-23 2010-05-26 精达制药公司 促胰岛素释放肽的混悬制剂及其应用
WO2009102467A2 (en) 2008-02-13 2009-08-20 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
JP5718925B2 (ja) 2009-09-28 2015-05-13 インターシア セラピューティクス，インコーポレイティド 実質的な定常状態薬物送達の迅速な確立及び／又は停止
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2013024158A1 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of protein kinase inhibitors and interferons or of protein kinase inhibitors and direct acting antivirals for the treatment and the prevention of hcv infection
WO2014033266A1 (en) 2012-08-31 2014-03-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
WO2016196851A2 (en) 2015-06-03 2016-12-08 Intarcia Therapeutics, Inc. Implant placement and removal systems
WO2017200943A1 (en) 2016-05-16 2017-11-23 Intarcia Therapeutics, Inc. Glucagon-receptor selective polypeptides and methods of use thereof
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
KR20190104039A (ko) 2017-01-03 2019-09-05 인타르시아 세라퓨틱스 인코포레이티드 Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2906160A1 (de) * 1979-02-17 1980-09-04 Thomae Gmbh Dr K Verbessertes verfahren zur herstellung von humaninterferon
AU538665B2 (en) * 1979-10-30 1984-08-23 Juridical Foundation, Japanese Foundation For Cancer Research Human interferon dna
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
PT72322B (en) * 1980-01-08 1982-09-23 Biogen Nv Process for preparation of recombinant dna molecules and of polipeptides similar to human interferon
GB2068970B (en) * 1980-02-06 1983-06-22 Searle & Co Recombinant dna technique for the preparation of a protein resembling human interferon
DE3005843A1 (de) * 1980-02-16 1981-09-10 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
ES506955A0 (es) * 1980-11-10 1983-02-01 Genentech Inc Un procedimiento para producir un polipeptido antiviral.
DE3106982A1 (de) * 1981-02-25 1982-09-09 Dr. Karl Thomae Gmbh, 7950 Biberach "neues tridecadeoxynukleotid, verfahren zu seiner herstellung und verwendung"
IL63327A (en) * 1981-07-16 1985-11-29 Yeda Res & Dev Production of interferon beta1 and alpha-phage recombinants for its production in host bacteria
GB2108510B (en) 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof

Also Published As

Publication number Publication date
NO168538C (no) 1992-03-04
NO168538B (no) 1991-11-25
ES529360A0 (es) 1984-10-01
JPH0774238B2 (ja) 1995-08-09
HU196452B (en) 1988-11-28
ZA833845B (en) 1985-01-30
DE3379591D1 (en) 1989-05-18
DD211359C4 (de) 1986-09-24
AU565479B2 (en) 1987-09-17
IL68790A0 (en) 1983-09-30
NO831903L (no) 1983-11-29
HK112893A (en) 1993-10-29
DK164742B (da) 1992-08-10
DD211359A5 (de) 1984-07-11
IL68790A (en) 1991-06-10
JPS5925689A (ja) 1984-02-09
ATE42114T1 (de) 1989-04-15
JPH0678774A (ja) 1994-03-22
SU1346048A3 (ru) 1987-10-15
KR920006349B1 (ko) 1992-08-03
AU1504483A (en) 1983-12-01
GR79236B (da) 1984-10-22
DK239383D0 (da) 1983-05-27
FI831818A0 (fi) 1983-05-23
ES522762A0 (es) 1984-03-16
UA8037A1 (uk) 1995-12-26
DK164742C (da) 1992-12-28
JP2558422B2 (ja) 1996-11-27
SG38692G (en) 1992-09-04
EP0095702B1 (de) 1989-04-12
DE3220116A1 (de) 1983-12-01
ES8500321A1 (es) 1984-10-01
FI82072C (fi) 1991-01-10
US4820638A (en) 1989-04-11
MX9202815A (es) 1992-06-30
DE3220116C2 (da) 1993-02-18
ES8403522A1 (es) 1984-03-16
FI82072B (fi) 1990-09-28
EP0095702A1 (de) 1983-12-07
NZ204384A (en) 1986-11-12
FI831818L (fi) 1983-11-29
KR840004944A (ko) 1984-10-31

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