DK1631574T3 - Colchicosidanaloge - Google Patents

Colchicosidanaloge

Info

Publication number
DK1631574T3
DK1631574T3 DK04739355T DK04739355T DK1631574T3 DK 1631574 T3 DK1631574 T3 DK 1631574T3 DK 04739355 T DK04739355 T DK 04739355T DK 04739355 T DK04739355 T DK 04739355T DK 1631574 T3 DK1631574 T3 DK 1631574T3
Authority
DK
Denmark
Prior art keywords
colchicine
colchicosidanaloge
formula
demethylthio
demethyl
Prior art date
Application number
DK04739355T
Other languages
English (en)
Inventor
Gabriele Fontana
Ezio Bombardelli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of DK1631574T3 publication Critical patent/DK1631574T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/248—Colchicine radicals, e.g. colchicosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK04739355T 2003-06-06 2004-05-26 Colchicosidanaloge DK1631574T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001144A ITMI20031144A1 (it) 2003-06-06 2003-06-06 Analoghi del colchicoside.
PCT/EP2004/005645 WO2004111068A1 (en) 2003-06-06 2004-05-26 Colchicoside analogues

Publications (1)

Publication Number Publication Date
DK1631574T3 true DK1631574T3 (da) 2009-05-25

Family

ID=30131160

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04739355T DK1631574T3 (da) 2003-06-06 2004-05-26 Colchicosidanaloge

Country Status (24)

Country Link
US (1) US7683163B2 (da)
EP (1) EP1631574B1 (da)
JP (1) JP4718449B2 (da)
KR (1) KR101121374B1 (da)
CN (1) CN100348605C (da)
AT (1) ATE425174T1 (da)
AU (1) AU2004247346B2 (da)
BR (1) BRPI0411068B8 (da)
CA (1) CA2528223C (da)
CY (1) CY1109019T1 (da)
DE (1) DE602004019914D1 (da)
DK (1) DK1631574T3 (da)
ES (1) ES2321838T3 (da)
HK (1) HK1090062A1 (da)
IL (1) IL172358A (da)
IT (1) ITMI20031144A1 (da)
MX (1) MXPA05013161A (da)
NO (1) NO330964B1 (da)
NZ (1) NZ543943A (da)
PL (1) PL1631574T3 (da)
PT (1) PT1631574E (da)
RU (1) RU2343157C2 (da)
SI (1) SI1631574T1 (da)
WO (1) WO2004111068A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20051418A1 (it) * 2005-07-22 2007-01-23 Indena Spa Analoghi del tiocolchicoside ad attivita'miorilassante e antiinfiammatoria
WO2008067039A2 (en) * 2006-10-06 2008-06-05 Wisconsin Alumni Research Foundation Colchicine neoglycosides and methods for their synthesis and use
PL2128170T3 (pl) * 2008-05-28 2011-05-31 Indena Spa Sposób glikozydacji kolchicyny i tiokolchicyny
US8722205B2 (en) 2009-03-23 2014-05-13 Universal Display Corporation Heteroleptic iridium complex
US8497290B2 (en) * 2009-05-27 2013-07-30 Takeda Pharmaceuticals U.S.A., Inc. Thiocolchicine derivatives, method of making and methods of use thereof
JP2015514715A (ja) * 2012-03-30 2015-05-21 タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド コルヒチン製剤、その製造方法および使用方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH341831A (fr) * 1955-06-10 1959-10-31 Uclaf Societe Anonyme Procédé de préparation de produits de condensation de saccharides sur l'azote des N-désacétyl-alcoylthiocolchicéines
GB773729A (en) * 1955-06-10 1957-05-01 Roussel Uclaf New derivatives of n-deacetylalkylthiocolchiceines and process for their production
JPS5619357B2 (da) * 1972-05-02 1981-05-07
JP2894366B2 (ja) * 1990-12-25 1999-05-24 有限会社尾源研究所 デアセチルコルヒチンの製造方法
AU634921B2 (en) * 1990-12-25 1993-03-04 Ohgen Research Laboratories Ltd. Deacetylcolchicine derivatives
IT1270124B (it) * 1994-10-05 1997-04-28 Indena Spa Derivati della colchicina e loro impiego terapeutico
IT1276996B1 (it) * 1995-06-27 1997-11-04 Indena Spa Derivati della colchicina, loro uso e formulazioni che li contengono
IT1282584B1 (it) * 1996-02-08 1998-03-31 Indena Spa Processo di glicosidazione di derivati colchicinici e prodotti ottenuti
IT1285777B1 (it) * 1996-10-07 1998-06-18 Indena Spa Processo di biotrasformazione di composti colchicinoidi nei corrispondenti 3-glicosilderivati
CN1208003A (zh) * 1997-08-08 1999-02-17 韩财元 摆翼式直升飞机
FR2779147B1 (fr) * 1998-05-27 2000-06-30 Synthelabo Derive de thiocolchicoside sa preparation et son application en therapeutique

Also Published As

Publication number Publication date
EP1631574B1 (en) 2009-03-11
RU2005137870A (ru) 2006-06-10
BRPI0411068A (pt) 2006-08-01
KR20060057536A (ko) 2006-05-26
US7683163B2 (en) 2010-03-23
JP4718449B2 (ja) 2011-07-06
PL1631574T3 (pl) 2009-07-31
AU2004247346B2 (en) 2008-12-18
US20070129315A1 (en) 2007-06-07
SI1631574T1 (sl) 2009-06-30
EP1631574A1 (en) 2006-03-08
AU2004247346A1 (en) 2004-12-23
RU2343157C2 (ru) 2009-01-10
CA2528223A1 (en) 2004-12-23
NO20055754L (no) 2005-12-05
DE602004019914D1 (de) 2009-04-23
CN100348605C (zh) 2007-11-14
MXPA05013161A (es) 2006-03-17
BRPI0411068B1 (pt) 2017-12-26
CY1109019T1 (el) 2014-07-02
CN1802383A (zh) 2006-07-12
CA2528223C (en) 2011-11-22
PT1631574E (pt) 2009-05-05
KR101121374B1 (ko) 2012-03-09
IL172358A0 (en) 2009-02-11
ATE425174T1 (de) 2009-03-15
ITMI20031144A0 (it) 2003-06-06
BRPI0411068B8 (pt) 2021-05-25
IL172358A (en) 2012-01-31
ITMI20031144A1 (it) 2004-12-07
ES2321838T3 (es) 2009-06-12
NO330964B1 (no) 2011-08-29
WO2004111068A1 (en) 2004-12-23
HK1090062A1 (en) 2006-12-15
NZ543943A (en) 2008-09-26
JP2006527173A (ja) 2006-11-30

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