ATE425174T1 - Colchicosidanaloge - Google Patents

Colchicosidanaloge

Info

Publication number
ATE425174T1
ATE425174T1 AT04739355T AT04739355T ATE425174T1 AT E425174 T1 ATE425174 T1 AT E425174T1 AT 04739355 T AT04739355 T AT 04739355T AT 04739355 T AT04739355 T AT 04739355T AT E425174 T1 ATE425174 T1 AT E425174T1
Authority
AT
Austria
Prior art keywords
colchicoside
analogues
colchicine
formula
demethylthio
Prior art date
Application number
AT04739355T
Other languages
English (en)
Inventor
Ezio Bombardelli
Gabriele Fontana
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of ATE425174T1 publication Critical patent/ATE425174T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/248—Colchicine radicals, e.g. colchicosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
AT04739355T 2003-06-06 2004-05-26 Colchicosidanaloge ATE425174T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001144A ITMI20031144A1 (it) 2003-06-06 2003-06-06 Analoghi del colchicoside.

Publications (1)

Publication Number Publication Date
ATE425174T1 true ATE425174T1 (de) 2009-03-15

Family

ID=30131160

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04739355T ATE425174T1 (de) 2003-06-06 2004-05-26 Colchicosidanaloge

Country Status (24)

Country Link
US (1) US7683163B2 (de)
EP (1) EP1631574B1 (de)
JP (1) JP4718449B2 (de)
KR (1) KR101121374B1 (de)
CN (1) CN100348605C (de)
AT (1) ATE425174T1 (de)
AU (1) AU2004247346B2 (de)
BR (1) BRPI0411068B8 (de)
CA (1) CA2528223C (de)
CY (1) CY1109019T1 (de)
DE (1) DE602004019914D1 (de)
DK (1) DK1631574T3 (de)
ES (1) ES2321838T3 (de)
HK (1) HK1090062A1 (de)
IL (1) IL172358A (de)
IT (1) ITMI20031144A1 (de)
MX (1) MXPA05013161A (de)
NO (1) NO330964B1 (de)
NZ (1) NZ543943A (de)
PL (1) PL1631574T3 (de)
PT (1) PT1631574E (de)
RU (1) RU2343157C2 (de)
SI (1) SI1631574T1 (de)
WO (1) WO2004111068A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20051418A1 (it) * 2005-07-22 2007-01-23 Indena Spa Analoghi del tiocolchicoside ad attivita'miorilassante e antiinfiammatoria
WO2008067039A2 (en) * 2006-10-06 2008-06-05 Wisconsin Alumni Research Foundation Colchicine neoglycosides and methods for their synthesis and use
ES2356494T3 (es) * 2008-05-28 2011-04-08 Indena S.P.A. Procedimiento para la glucosidación de colchicina y tiocolchicina.
US8722205B2 (en) 2009-03-23 2014-05-13 Universal Display Corporation Heteroleptic iridium complex
CN102448930A (zh) * 2009-05-27 2012-05-09 共有药物有限公司 硫代秋水仙碱衍生物、其制造方法和使用方法
JP2015514715A (ja) * 2012-03-30 2015-05-21 タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド コルヒチン製剤、その製造方法および使用方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB773729A (en) * 1955-06-10 1957-05-01 Roussel Uclaf New derivatives of n-deacetylalkylthiocolchiceines and process for their production
CH341831A (fr) 1955-06-10 1959-10-31 Uclaf Societe Anonyme Procédé de préparation de produits de condensation de saccharides sur l'azote des N-désacétyl-alcoylthiocolchicéines
JPS5619357B2 (de) * 1972-05-02 1981-05-07
AU634921B2 (en) * 1990-12-25 1993-03-04 Ohgen Research Laboratories Ltd. Deacetylcolchicine derivatives
JP2894366B2 (ja) * 1990-12-25 1999-05-24 有限会社尾源研究所 デアセチルコルヒチンの製造方法
IT1270124B (it) * 1994-10-05 1997-04-28 Indena Spa Derivati della colchicina e loro impiego terapeutico
IT1276996B1 (it) * 1995-06-27 1997-11-04 Indena Spa Derivati della colchicina, loro uso e formulazioni che li contengono
IT1282584B1 (it) 1996-02-08 1998-03-31 Indena Spa Processo di glicosidazione di derivati colchicinici e prodotti ottenuti
IT1285777B1 (it) * 1996-10-07 1998-06-18 Indena Spa Processo di biotrasformazione di composti colchicinoidi nei corrispondenti 3-glicosilderivati
CN1208003A (zh) * 1997-08-08 1999-02-17 韩财元 摆翼式直升飞机
FR2779147B1 (fr) * 1998-05-27 2000-06-30 Synthelabo Derive de thiocolchicoside sa preparation et son application en therapeutique

Also Published As

Publication number Publication date
WO2004111068A1 (en) 2004-12-23
MXPA05013161A (es) 2006-03-17
EP1631574A1 (de) 2006-03-08
AU2004247346A1 (en) 2004-12-23
ITMI20031144A1 (it) 2004-12-07
HK1090062A1 (en) 2006-12-15
CY1109019T1 (el) 2014-07-02
NO330964B1 (no) 2011-08-29
BRPI0411068A (pt) 2006-08-01
IL172358A (en) 2012-01-31
SI1631574T1 (sl) 2009-06-30
PT1631574E (pt) 2009-05-05
ITMI20031144A0 (it) 2003-06-06
US20070129315A1 (en) 2007-06-07
KR20060057536A (ko) 2006-05-26
NO20055754L (no) 2005-12-05
EP1631574B1 (de) 2009-03-11
NZ543943A (en) 2008-09-26
DK1631574T3 (da) 2009-05-25
CN100348605C (zh) 2007-11-14
US7683163B2 (en) 2010-03-23
IL172358A0 (en) 2009-02-11
ES2321838T3 (es) 2009-06-12
CA2528223C (en) 2011-11-22
CN1802383A (zh) 2006-07-12
CA2528223A1 (en) 2004-12-23
JP2006527173A (ja) 2006-11-30
JP4718449B2 (ja) 2011-07-06
BRPI0411068B8 (pt) 2021-05-25
DE602004019914D1 (de) 2009-04-23
PL1631574T3 (pl) 2009-07-31
RU2005137870A (ru) 2006-06-10
KR101121374B1 (ko) 2012-03-09
BRPI0411068B1 (pt) 2017-12-26
AU2004247346B2 (en) 2008-12-18
RU2343157C2 (ru) 2009-01-10

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