CY1107483T1 - Παραγωγα πυριδαζινης, η χρηση τους ως φαρμακευτικα σκευασματα και η διαδικασια παρασκευης τους - Google Patents
Παραγωγα πυριδαζινης, η χρηση τους ως φαρμακευτικα σκευασματα και η διαδικασια παρασκευης τουςInfo
- Publication number
- CY1107483T1 CY1107483T1 CY20061101281T CY061101281T CY1107483T1 CY 1107483 T1 CY1107483 T1 CY 1107483T1 CY 20061101281 T CY20061101281 T CY 20061101281T CY 061101281 T CY061101281 T CY 061101281T CY 1107483 T1 CY1107483 T1 CY 1107483T1
- Authority
- CY
- Cyprus
- Prior art keywords
- preparation process
- pharmaceutical preparations
- pyridazine derivatives
- pyridazine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Η εφεύρεση έχει ως αντικείμενο τα προϊόντα της φόρμουλας : στην οποία το R1 αναπαριστά ένα άτομο υδρογόνου ή μια ομάδα COR, COOR, αρυλίου, αραλκυλίου, που τελικά αντικαθίσταται, το R2 αναπαριστά μια ομάδα που απαντά στην ακόλουθη φόρμουλα (II) στην οποία το n τιμάται 0, 1, 2 ή 3, το Χ μπορεί να είναι μια ομάδα μονοκυκλικού ή δικυκλικού ετερόκυκλου κορεσμένου ή ακόρεστου, ή μια ομάδα αρυλίου, ή μια ομάδα NR4R5, ή μια ομάδα COR, το R3 είναι ομάδα της φόρμουλας -Υ -(CH2)m-C (CN) R6R7, στην οποία το Υ είναι ένα άτομο οξυγόνου ή μια ομάδα -N(R8)-, το m τιμάται 0, 1,2 ή 3. Τα προϊόντα αυτά προορίζονται για την πρόληψη ή τη θεραπεία νόσων στις οποίες εμπλέκονται μεταβολικά ένζυμα που επιλέγονται ανάμεσα στις πρωτεάσεις και τις κινάσεις.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0201632A FR2835835B1 (fr) | 2002-02-11 | 2002-02-11 | Nouveaux derives de la pyridazine, leur utilisation comme medicaments, compositions pharmaceutiques et leur procede de preparation |
| EP03717380A EP1476434B1 (fr) | 2002-02-11 | 2003-02-07 | Derives de la pyridazine, leur utilisation comme medicaments, et leur procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1107483T1 true CY1107483T1 (el) | 2013-03-13 |
Family
ID=27620073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061101281T CY1107483T1 (el) | 2002-02-11 | 2006-09-07 | Παραγωγα πυριδαζινης, η χρηση τους ως φαρμακευτικα σκευασματα και η διαδικασια παρασκευης τους |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7223758B2 (el) |
| EP (1) | EP1476434B1 (el) |
| JP (1) | JP4447324B2 (el) |
| AT (1) | ATE329907T1 (el) |
| AU (1) | AU2003222363A1 (el) |
| BR (1) | BR0307565A (el) |
| CA (1) | CA2475439A1 (el) |
| CY (1) | CY1107483T1 (el) |
| DE (1) | DE60306122T2 (el) |
| DK (1) | DK1476434T3 (el) |
| ES (1) | ES2266806T3 (el) |
| FR (1) | FR2835835B1 (el) |
| MX (1) | MXPA04007186A (el) |
| PT (1) | PT1476434E (el) |
| WO (1) | WO2003068140A2 (el) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2839309B1 (fr) * | 2002-05-03 | 2004-07-23 | Aventis Pharma Sa | Nouveaux derives de l'acide hexahydro-pyridazine-3- carboxylique, chimiotheques les contenant, leur utilisation comme medicaments, compositions pharmaceutiques les contenant et leurs procedes de preparation |
| JP2008531503A (ja) * | 2005-02-23 | 2008-08-14 | スミスクライン ビーチャム コーポレーション | グルココルチコイド受容体のモジュレーターとしてのナフタレン誘導体 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0621270T3 (da) * | 1991-11-08 | 2000-07-17 | Sankyo Co | Piperazinderivater som collagenaseinhibitorer |
-
2002
- 2002-02-11 FR FR0201632A patent/FR2835835B1/fr not_active Expired - Fee Related
-
2003
- 2003-02-07 CA CA002475439A patent/CA2475439A1/fr not_active Abandoned
- 2003-02-07 MX MXPA04007186A patent/MXPA04007186A/es unknown
- 2003-02-07 AU AU2003222363A patent/AU2003222363A1/en not_active Abandoned
- 2003-02-07 ES ES03717380T patent/ES2266806T3/es not_active Expired - Lifetime
- 2003-02-07 WO PCT/FR2003/000381 patent/WO2003068140A2/fr active IP Right Grant
- 2003-02-07 BR BR0307565-6A patent/BR0307565A/pt not_active IP Right Cessation
- 2003-02-07 AT AT03717380T patent/ATE329907T1/de active
- 2003-02-07 JP JP2003567325A patent/JP4447324B2/ja not_active Expired - Fee Related
- 2003-02-07 DE DE60306122T patent/DE60306122T2/de not_active Expired - Lifetime
- 2003-02-07 PT PT03717380T patent/PT1476434E/pt unknown
- 2003-02-07 EP EP03717380A patent/EP1476434B1/fr not_active Expired - Lifetime
- 2003-02-07 DK DK03717380T patent/DK1476434T3/da active
-
2004
- 2004-08-11 US US10/916,175 patent/US7223758B2/en not_active Expired - Lifetime
-
2006
- 2006-09-07 CY CY20061101281T patent/CY1107483T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1476434T3 (da) | 2006-10-16 |
| JP2005525334A (ja) | 2005-08-25 |
| DE60306122T2 (de) | 2007-06-06 |
| EP1476434A2 (fr) | 2004-11-17 |
| MXPA04007186A (es) | 2004-10-29 |
| ATE329907T1 (de) | 2006-07-15 |
| US7223758B2 (en) | 2007-05-29 |
| FR2835835B1 (fr) | 2004-04-16 |
| EP1476434B1 (fr) | 2006-06-14 |
| WO2003068140A3 (fr) | 2004-04-08 |
| BR0307565A (pt) | 2004-12-21 |
| CA2475439A1 (fr) | 2003-08-21 |
| US20050165017A1 (en) | 2005-07-28 |
| DE60306122D1 (de) | 2006-07-27 |
| FR2835835A1 (fr) | 2003-08-15 |
| AU2003222363A1 (en) | 2003-09-04 |
| JP4447324B2 (ja) | 2010-04-07 |
| ES2266806T3 (es) | 2007-03-01 |
| PT1476434E (pt) | 2006-10-31 |
| WO2003068140A2 (fr) | 2003-08-21 |
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