DK161080C - Krystallinsk hydrat af oralt anvendeligt cephalosporin og praeparat dermed - Google Patents

Krystallinsk hydrat af oralt anvendeligt cephalosporin og praeparat dermed

Info

Publication number
DK161080C
DK161080C DK336487A DK336487A DK161080C DK 161080 C DK161080 C DK 161080C DK 336487 A DK336487 A DK 336487A DK 336487 A DK336487 A DK 336487A DK 161080 C DK161080 C DK 161080C
Authority
DK
Denmark
Prior art keywords
crystallic
hydrate
preparation
oral
used cephalosporin
Prior art date
Application number
DK336487A
Other languages
Danish (da)
English (en)
Other versions
DK161080B (da
DK336487D0 (da
DK336487A (da
Inventor
Yoshio Hamashima
Kyoji Minami
Kyozo Kawata
Teruo Sakamoto
Toyohiko Takeda
Yusuke Suzuki
Masanori Tujikawa
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61156954A external-priority patent/JP2544113B2/ja
Priority claimed from JP21626086A external-priority patent/JPH0717651B2/ja
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of DK336487D0 publication Critical patent/DK336487D0/da
Publication of DK336487A publication Critical patent/DK336487A/da
Publication of DK161080B publication Critical patent/DK161080B/da
Application granted granted Critical
Publication of DK161080C publication Critical patent/DK161080C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
DK336487A 1986-07-02 1987-06-30 Krystallinsk hydrat af oralt anvendeligt cephalosporin og praeparat dermed DK161080C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP61156954A JP2544113B2 (ja) 1986-07-02 1986-07-02 安定なカプセル製剤
JP15695486 1986-07-02
JP21626086A JPH0717651B2 (ja) 1986-09-12 1986-09-12 経口投与用セフアロスポリン水和物結晶
JP21626086 1986-09-12

Publications (4)

Publication Number Publication Date
DK336487D0 DK336487D0 (da) 1987-06-30
DK336487A DK336487A (da) 1988-01-03
DK161080B DK161080B (da) 1991-05-27
DK161080C true DK161080C (da) 1991-11-11

Family

ID=26484565

Family Applications (1)

Application Number Title Priority Date Filing Date
DK336487A DK161080C (da) 1986-07-02 1987-06-30 Krystallinsk hydrat af oralt anvendeligt cephalosporin og praeparat dermed

Country Status (27)

Country Link
US (2) US4812561A (es)
KR (1) KR950005302B1 (es)
CN (1) CN1015106B (es)
AR (1) AR243893A1 (es)
AT (1) AT392472B (es)
AU (1) AU594167B2 (es)
BE (1) BE1001691A4 (es)
CA (1) CA1283405C (es)
CH (1) CH672788A5 (es)
DE (1) DE3721913A1 (es)
DK (1) DK161080C (es)
ES (2) ES2004952A6 (es)
FI (1) FI89052C (es)
FR (1) FR2601014B1 (es)
GB (1) GB2192183B (es)
GR (1) GR871014B (es)
HK (1) HK47893A (es)
HU (1) HU200777B (es)
IE (1) IE59613B1 (es)
IL (1) IL83059A (es)
IT (1) IT1211469B (es)
NL (1) NL193136C (es)
NO (1) NO170889C (es)
NZ (1) NZ220764A (es)
PL (1) PL159180B1 (es)
RU (1) RU1829932C (es)
SE (1) SE466257B (es)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089270A (en) * 1990-05-15 1992-02-18 L. Perrigo Company Capsule-shaped tablet
CZ283428B6 (cs) * 1992-04-30 1998-04-15 Schering Corporation Stabilní hydratovaný suchý práškový cefalosporin vhodný pro orální aplikaci ve formě suspenze
DE69924965T3 (de) * 1998-10-27 2023-03-09 Westlake Longview Corp. Verfahren zur polymerisierung von olefine; polyethylene, und filme, und gegenstände damit hergestellt
US6544555B2 (en) * 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
AT412213B (de) * 2000-05-30 2004-11-25 Sandoz Ag Verfahren zur trocknung von amoxicillin oder amoxicillin-hältigen, oralen, festen pharmazeutischen zusammensetzungen unter verwendung eines gases mit einer definierten gasfeuchte
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
EP1648418A4 (en) * 2003-07-21 2011-11-16 Middlebrook Pharmaceuticals Inc ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION
WO2005009365A2 (en) * 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
CA2533292C (en) * 2003-07-21 2013-12-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
US8758820B2 (en) * 2003-08-11 2014-06-24 Shionogi Inc. Robust pellet
CA2535398C (en) * 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
CA2535780A1 (en) * 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
AU2004273830B2 (en) * 2003-09-15 2011-03-24 Shionogi, Inc. Antibiotic product, use and formulation thereof
AU2004308419B2 (en) * 2003-12-24 2011-06-02 Victory Pharma, Inc. Enhanced absorption of modified release dosage forms
EP1771158A4 (en) * 2004-07-02 2008-03-12 Advancis Pharmaceutical Corp TABLET FOR PULSED DELIVERY
US20110104109A1 (en) * 2005-07-13 2011-05-05 Frank Bennett Tetracyclic indole derivatives and their use for treating or preventing viral infections
EP3173084B1 (en) 2005-11-11 2019-10-23 Boehringer Ingelheim International GmbH Quinazoline derivatives for the treatment of cancer diseases
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) * 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
AR062927A1 (es) * 2006-10-11 2008-12-17 Bayer Healthcare Ag 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
US8546420B2 (en) * 2006-12-22 2013-10-01 Merck Sharp & Dohme Corp. 4, 5-ring annulated indole derivatives for treating or preventing of HCV and related viral infections
US8557848B2 (en) 2006-12-22 2013-10-15 Merck Sharp & Dohme Corp. 4,5-ring annulated indole derivatives for treating or preventing of HCV and related viral infections
CA2674831A1 (en) 2006-12-22 2008-11-13 Schering Corporation 5,6-ring annulated indole derivatives and methods of use thereof
WO2009032125A1 (en) * 2007-08-29 2009-03-12 Schering Corporation 2,3-substituted azaindole derivatives for treating viral infections
KR20100049667A (ko) * 2007-08-29 2010-05-12 쉐링 코포레이션 바이러스 감염 치료용 2,3-치환된 인돌 유도체
BRPI0815811A2 (pt) * 2007-08-29 2015-02-18 Schering Corp Derivados de indol substituído e métodos de uso dos mesmos
WO2009064852A1 (en) * 2007-11-16 2009-05-22 Schering Corporation 3-aminosulfonyl substituted indole derivatives and methods of use thereof
CA2705586A1 (en) * 2007-11-16 2009-05-22 Schering Corporation 3-heterocyclic substituted indole derivatives and methods of use thereof
AR072088A1 (es) * 2008-06-13 2010-08-04 Schering Corp Derivados de indol triciclicos y sus metodos de uso
WO2010022125A1 (en) 2008-08-20 2010-02-25 Schering Corporation Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
CA2734486A1 (en) 2008-08-20 2010-02-25 Southern Research Institute Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
AU2009282574B2 (en) 2008-08-20 2014-08-21 Merck Sharp & Dohme Corp. Ethenyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
AU2009282572B2 (en) 2008-08-20 2014-09-11 Merck Sharp & Dohme Corp. Azo-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
CA2763140A1 (en) 2009-05-29 2010-12-02 Schering Corporation Antiviral compounds composed of three linked aryl moieties to treat diseases such as hepatitis c
PT2451445T (pt) 2009-07-06 2019-07-10 Boehringer Ingelheim Int Processo para secagem de bibw2992, dos seus sais e de formulações farmacêuticas sólidas compreendendo este ingrediente ativo
CA2782024A1 (en) 2009-11-25 2011-06-03 Schering Corporation Fused tricyclic compounds and derivatives thereof useful for the treatment of viral diseases
JP2013515068A (ja) 2009-12-22 2013-05-02 メルク・シャープ・アンド・ドーム・コーポレーション ウイルス性疾患の治療のための縮合三環式化合物およびその使用方法
US9433621B2 (en) 2010-02-18 2016-09-06 Merck Sharp & Dohme Corp. Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
MX2012010392A (es) 2010-03-09 2012-10-03 Merck Sharp & Dohme Compuesto de sililo triciclicos fusionados y metodos de uso de los mismos para el tratamiento de enfermedades virales.
EP2566449B1 (en) 2010-05-04 2014-10-08 Mahmut Bilgic Pharmaceutical compositions comprising ceftibuten
EP2598149A4 (en) 2010-07-26 2014-09-10 Merck Sharp & Dohme SUBSTITUTED BIPHENYLENE COMPOUNDS AND METHOD FOR USE THEREOF FOR THE TREATMENT OF VIRUS DISEASES
CA2812779A1 (en) 2010-09-29 2012-04-19 Merck Sharp & Dohme Corp. Fused tetracycle derivatives and methods of use thereof for the treatment of viral diseases
JP2014515023A (ja) 2011-04-13 2014-06-26 メルク・シャープ・アンド・ドーム・コーポレーション ２’−置換ヌクレオシド誘導体およびウイルス疾患の処置のためのその使用方法
EP2697242B1 (en) 2011-04-13 2018-10-03 Merck Sharp & Dohme Corp. 2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
WO2013033900A1 (en) 2011-09-08 2013-03-14 Merck Sharp & Dohme Corp. Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases
WO2013033899A1 (en) 2011-09-08 2013-03-14 Merck Sharp & Dohme Corp. Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
WO2013033901A1 (en) 2011-09-08 2013-03-14 Merck Sharp & Dohme Corp. Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases
EP2755981A4 (en) 2011-09-14 2015-03-25 Merck Sharp & Dohme HETEROCYCLIC COMPOUNDS CONTAINING SILYL AND METHODS OF USING THE SAME FOR TREATING VIRAL DISEASES
EP2833874A1 (en) * 2012-04-04 2015-02-11 Mahmut Bilgic Capsule formulations comprising ceftibuten
EP2815743A1 (en) 2013-06-21 2014-12-24 Sanovel Ilac Sanayi ve Ticaret A.S. Ceftibuten formulations
WO2015065817A1 (en) 2013-10-30 2015-05-07 Merck Sharp & Dohme Corp. Pseudopolymorphs of an hcv ns5a inhibitor and uses thereof
US9242965B2 (en) 2013-12-31 2016-01-26 Boehringer Ingelheim International Gmbh Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors
CN103948932B (zh) * 2014-04-17 2016-03-16 海南日中天制药有限公司 一种头孢克肟组合物及其制备方法
EP3031450A1 (en) 2014-12-12 2016-06-15 Sanovel Ilac Sanayi ve Ticaret A.S. Ceftibuten capsule compositions
BR112018073424A2 (pt) 2016-05-13 2019-03-26 Aeromics, Inc. cristais
CN106397455B (zh) * 2016-08-30 2018-08-31 山东罗欣药业集团恒欣药业有限公司 一种抗感染药物头孢布烯晶体化合物及其组合物
CN106397454B (zh) * 2016-08-30 2018-08-24 山东罗欣药业集团股份有限公司 一种抗感染药物头孢布烯晶型化合物及其组合物
CN106432271A (zh) * 2016-09-21 2017-02-22 临沂草之美医药科技有限公司 一种治疗外科手术感染的药物头孢布烯晶体化合物
CN106397457A (zh) * 2016-09-21 2017-02-15 临沂草之美医药科技有限公司 一种治疗外科手术感染的药物头孢布烯晶体化合物
CN106432270A (zh) * 2016-09-21 2017-02-22 临沂草之美医药科技有限公司 一种制备治疗外科手术感染的药物头孢布烯晶体化合物的方法
CN106432272A (zh) * 2016-09-21 2017-02-22 临沂草之美医药科技有限公司 一种制备治疗外科手术感染的药物头孢布烯晶体化合物的方法
EP4362950A1 (en) * 2021-07-01 2024-05-08 Qpex Biopharma, Inc. Crystalline forms of ceftibuten

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3819620A (en) * 1972-06-01 1974-06-25 Squibb & Sons Inc 7-(d-alpha-amino-1,4-cyclohexadien-1-ylacet-amido)desacetoxycephalosporanic acid dihydrate
JPS5726692A (en) * 1980-07-22 1982-02-12 Fujisawa Pharmaceut Co Ltd Preparation of stable crystal of salt of ceftizoxime
DE3037997A1 (de) * 1980-10-08 1982-05-13 Bayer Ag (beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
AU575854B2 (en) * 1983-10-04 1988-08-11 Shionogi & Co., Ltd. 7beta-(carboxyalkenamido) cephalosporins
AU580855B2 (en) * 1985-03-29 1989-02-02 Shionogi & Co., Ltd. Alkeneamidocephalosporin esters

Also Published As

Publication number Publication date
KR880001670A (ko) 1988-04-26
NL193136C (nl) 1998-12-04
FI89052B (fi) 1993-04-30
IE871738L (en) 1988-01-02
SE8702705L (sv) 1988-01-03
PL159180B1 (pl) 1992-11-30
FR2601014B1 (fr) 1990-09-14
NZ220764A (en) 1989-09-27
NL193136B (nl) 1998-08-03
NO872729D0 (no) 1987-06-30
RU1829932C (ru) 1993-07-23
HK47893A (en) 1993-05-27
US4933443A (en) 1990-06-12
SE466257B (sv) 1992-01-20
CN87105009A (zh) 1988-03-23
NO170889C (no) 1992-12-23
GR871014B (en) 1987-11-02
IE59613B1 (en) 1994-03-09
GB2192183A (en) 1988-01-06
BE1001691A4 (fr) 1990-02-13
AR243893A1 (es) 1993-09-30
DK161080B (da) 1991-05-27
AT392472B (de) 1991-04-10
IT1211469B (it) 1989-11-03
SE8702705D0 (sv) 1987-06-30
CH672788A5 (es) 1989-12-29
IL83059A (en) 1992-03-29
CN1015106B (zh) 1991-12-18
FI89052C (fi) 1993-08-10
IL83059A0 (en) 1987-12-31
GB8715064D0 (en) 1987-08-05
FR2601014A1 (fr) 1988-01-08
PL266567A1 (en) 1988-07-21
CA1283405C (en) 1991-04-23
NO872729L (no) 1988-01-04
NL8701507A (nl) 1988-02-01
HU200777B (en) 1990-08-28
AU7504087A (en) 1988-01-07
DK336487D0 (da) 1987-06-30
HUT44257A (en) 1988-02-29
ES2004952A6 (es) 1989-02-16
AU594167B2 (en) 1990-03-01
US4812561A (en) 1989-03-14
FI872903A (fi) 1988-01-03
FI872903A0 (fi) 1987-07-01
DE3721913A1 (de) 1988-01-07
GB2192183B (en) 1990-05-16
DK336487A (da) 1988-01-03
ATA165887A (de) 1990-09-15
ES2008759A6 (es) 1989-08-01
KR950005302B1 (ko) 1995-05-23
IT8767566A0 (it) 1987-07-01
NO170889B (no) 1992-09-14

Similar Documents

Publication Publication Date Title
DK161080C (da) Krystallinsk hydrat af oralt anvendeligt cephalosporin og praeparat dermed
DK263288D0 (da) Farmaceutisk praeparat af cefuroxim-axetil
DK385388D0 (da) Anvendelse af 5ht-3-antagonister
DK350489D0 (da) Elektrisk resonator og anvendelse af resonator
DK196986D0 (da) Fremstilling af polysaccharider
DK154648C (da) Blandingssalte af glukosaminsulfat og fremgangsmaade til fremstilling deraf
DK481987A (da) Keramisk skum og fremgangsmaade til fremstilling af keramisk genstand
DK549688D0 (da) Fremstilling af peptider
PT88440A (pt) Salbutamol-containing plaster and method of producing
DK108190D0 (da) Stereoselektiv fremstilling af 3-substituerede 4-(phenylanilo)piperidinforbindelser og derivater
DK115288A (da) Pesticid anvendelse af 2-phenylimidazolderivater samt 2-phenyl-imidazolderivater og fremgangsmaader til deres fremstilling
DK87888D0 (da) Terapeutisk anvendelse af tindijoddeuteroporfyrin
DK119688A (da) 23-oxo- (-keto-) og 23-imino-derivater af mono- og diepoxy-ll-f28249-forbindelser
DK625684A (da) Praeparater af i vand tungtoploeselige anthelmintika og fremgangsmaadertil deres fremstilling
DK300488D0 (da) Mono- og polyhydroxyacylderivater af polyoxygenerede labdaner, deres fremstilling og anvendelse
DK446388D0 (da) Pyrazinoxidforbindelse af nf-1616 -904 og farmaceutisk praeparat indeholdende denne
IT1231426B (it) Preparazione di polifluoroenolati
DK626984A (da) Estere af cephalosporinderivater, deres fremstilling og anvendelse
DK135387D0 (da) Fremstilling af proteiner
DK79886A (da) Krystallinsk form af 7-(dimethylaminomethylen)-amino-9a-methoxymitosan
DK119488D0 (da) Mono- og diepoxidderivater af 23-deoxy-ll-f28249-forbindelser
DK626784A (da) Fremgangsmaade og rensning af alkylerede antraquinoner
DK151588A (da) Imidazol-2-thionpraeparat til mundskylning af reperfusionsskader
DK26986A (da) Sammenkobling af fortrinsvis langstrakte elementer
DK321986D0 (da) Fremstilling af proteiner

Legal Events

Date Code Title Description
PUP Patent expired