DK1592441T3 - Listeria, hvis indtrængen i ikke-phagocytiske celler er svækket, vacciner omfattende listeria og fremgangsmåder til anvendelse deraf - Google Patents
Listeria, hvis indtrængen i ikke-phagocytiske celler er svækket, vacciner omfattende listeria og fremgangsmåder til anvendelse derafInfo
- Publication number
- DK1592441T3 DK1592441T3 DK04749316.8T DK04749316T DK1592441T3 DK 1592441 T3 DK1592441 T3 DK 1592441T3 DK 04749316 T DK04749316 T DK 04749316T DK 1592441 T3 DK1592441 T3 DK 1592441T3
- Authority
- DK
- Denmark
- Prior art keywords
- listeria
- attenuated
- vaccines
- entry
- phagocytic cells
- Prior art date
Links
- 241000186781 Listeria Species 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 230000002238 attenuated effect Effects 0.000 abstract 5
- 101710198693 Invasin Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 210000001539 phagocyte Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/07—Bacillus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44605103P | 2003-02-06 | 2003-02-06 | |
| US44915303P | 2003-02-21 | 2003-02-21 | |
| US49008903P | 2003-07-24 | 2003-07-24 | |
| US51171903P | 2003-10-15 | 2003-10-15 | |
| US51191903P | 2003-10-15 | 2003-10-15 | |
| US51186903P | 2003-10-15 | 2003-10-15 | |
| US54151504P | 2004-02-02 | 2004-02-02 | |
| PCT/US2004/003429 WO2004110481A2 (en) | 2003-02-06 | 2004-02-06 | Listeria attenuated for entry into non-phagocytic cells, vaccines comprising the listeria, and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1592441T3 true DK1592441T3 (da) | 2012-05-14 |
Family
ID=33556840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04749316.8T DK1592441T3 (da) | 2003-02-06 | 2004-02-06 | Listeria, hvis indtrængen i ikke-phagocytiske celler er svækket, vacciner omfattende listeria og fremgangsmåder til anvendelse deraf |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7691393B2 (enExample) |
| EP (1) | EP1592441B1 (enExample) |
| JP (2) | JP4545151B2 (enExample) |
| KR (1) | KR101192652B1 (enExample) |
| AT (1) | ATE552843T1 (enExample) |
| AU (1) | AU2004246999B2 (enExample) |
| CA (1) | CA2515369C (enExample) |
| DK (1) | DK1592441T3 (enExample) |
| ES (1) | ES2382332T3 (enExample) |
| MX (1) | MXPA05008342A (enExample) |
| PT (1) | PT1592441E (enExample) |
| WO (1) | WO2004110481A2 (enExample) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8114414B2 (en) * | 1994-11-08 | 2012-02-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical cancer |
| US7794729B2 (en) * | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
| US20070264279A1 (en) * | 1994-11-08 | 2007-11-15 | Claudia Gravekamp | Compositions and methods comprising a MAGE-b antigen |
| US8791237B2 (en) * | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
| US7820180B2 (en) * | 2004-09-24 | 2010-10-26 | The Trustees Of The University Of Pennsylvania | Listeria-based and LLO-based vaccines |
| US8956621B2 (en) | 1994-11-08 | 2015-02-17 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical dysplasia |
| US7662396B2 (en) * | 2001-03-26 | 2010-02-16 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
| US6099848A (en) * | 1997-11-18 | 2000-08-08 | The Trustees Of The University Of Pennsylvania | Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use |
| US9012141B2 (en) | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| AU2001255196A1 (en) * | 2000-03-29 | 2001-10-08 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing immunogenicity of antigens |
| US8771702B2 (en) | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
| US7700344B2 (en) | 2001-03-26 | 2010-04-20 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
| JP2005527240A (ja) * | 2002-05-29 | 2005-09-15 | ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 弱毒リステリア種とこれを使用する方法 |
| US7695725B2 (en) | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| ES2382332T3 (es) * | 2003-02-06 | 2012-06-07 | Aduro Biotech | Listeria atenuada para entrar en células no fagocíticas, vacunas que comprenden esta listeria y métodos de uso de las mismas |
| AU2004224425B2 (en) * | 2003-02-06 | 2010-06-24 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| US20050175630A1 (en) * | 2003-12-23 | 2005-08-11 | Eyal Raz | Immunogenic compositions and methods of use thereof |
| US7842289B2 (en) * | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| US20060003454A1 (en) * | 2004-07-02 | 2006-01-05 | Conjugon, Inc. | Non-dividing donor cells for gene transfer |
| WO2006045110A2 (en) * | 2004-10-18 | 2006-04-27 | Medimmune, Inc. | High cell density process for growth of listeria |
| US20060270040A1 (en) * | 2005-05-26 | 2006-11-30 | Conjugon, Inc. | Compositions and methods for treating tissue |
| US7935804B2 (en) | 2006-03-01 | 2011-05-03 | Aduro Biotech | Engineered Listeria and methods of use thereof |
| US20070207171A1 (en) * | 2006-03-01 | 2007-09-06 | Cerus Corporation | Engineered listeria and methods of use thereof |
| DK1991263T3 (en) * | 2006-03-01 | 2015-03-30 | Aduro Biotech | Prepared listeria and methods of use thereof |
| US8926993B2 (en) * | 2006-07-17 | 2015-01-06 | Aduro Biotech | Methods and compositions using Listeria for enhancing immunogenicity by prime boost |
| JP2009545330A (ja) * | 2006-08-04 | 2009-12-24 | ザ トラスティーズ オブ ザ ユニバーシティー オブ ぺンシルべニア | Ige依存性疾患を治療するための方法および組成物 |
| US8241636B2 (en) * | 2006-08-15 | 2012-08-14 | The Trustees Of The University Of Pennsylvania | Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof |
| US8268326B2 (en) * | 2006-08-15 | 2012-09-18 | The Trustees Of The University Of Pennsylvania | Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof |
| WO2008066774A2 (en) * | 2006-11-22 | 2008-06-05 | The Regents Of The University Of California | INTERFERON-β PRODUCTION MODULATING LISTERIA STRAINS AND METHODS FOR USING SAME |
| JP2010530005A (ja) * | 2007-06-15 | 2010-09-02 | イミュアールエックス・インコーポレーテッド | Tnf−rアゴニスト療法レジメンの毒性を緩和するためのtlrアゴニスト及び/又は1型インターフェロンの使用 |
| WO2009018465A1 (en) * | 2007-07-31 | 2009-02-05 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Vaccination with killed but metabolically active (kbma) protozoans with toll-like receptor agonists |
| WO2009143085A1 (en) | 2008-05-19 | 2009-11-26 | Anza Therapeutics, Inc. | Compositions comprising prfa*mutant listeria and methods of use thereof |
| ES2741730T3 (es) | 2008-05-19 | 2020-02-12 | Advaxis Inc | Sistema de administración doble para antígenos heterólogos que comprende una cepa de Listeria recombinante atenuada por la mutación de dal/dat y la deleción de ActA que comprende una molécula de ácido nucleico que codifica una proteína de fusión de listeriolisina O - antígeno prostático específico |
| US9017660B2 (en) * | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| ES2637068T3 (es) | 2009-03-04 | 2017-10-10 | The Trustees Of The University Of Pennsylvania | Composiciones que comprenden factores angiogénicos y métodos de uso de las mismas |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| US9161974B2 (en) | 2010-05-23 | 2015-10-20 | Aduro Biotech, Inc. | Methods and compositions using listeria for adjuvant treatment of cancer |
| US9226958B2 (en) | 2010-10-01 | 2016-01-05 | University Of Georgia Research Foundation, Inc. | Use of Listeria vaccine vectors to reverse vaccine unresponsiveness in parasitically infected individuals |
| EP2640842B1 (en) | 2010-11-17 | 2018-05-30 | Aduro Biotech, Inc. | Methods and compositions for inducing an immune response to egfrviii |
| AU2012229218B2 (en) * | 2011-03-11 | 2017-03-02 | Advaxis, Inc. | Listeria-based adjuvants |
| BR112013029916B1 (pt) | 2011-05-23 | 2021-02-09 | Lego Ns | sistema de construção de brinquedo, método implementado por computador para gerar uma imagem de um modelo de construção de brinquedo, sistema de processamento de dados, meio legível por computador, e conjunto de construção de brinquedo |
| HK1205944A1 (en) * | 2012-03-12 | 2015-12-31 | 阿德瓦希斯公司 | Suppressor cell function inhibition following listeria vaccine treatment |
| WO2013143555A1 (en) * | 2012-03-26 | 2013-10-03 | Biontech Ag | Rna formulation for immunotherapy |
| EP3207142A4 (en) | 2014-10-14 | 2018-07-04 | The Trustees Of The University Of Pennsylvania | Recombinant listeria vaccine strains and methods of using the same in cancer immunotherapy |
| EP3215139B1 (en) | 2014-11-03 | 2020-08-19 | Cerus Corporation | Compositions and methods for improved car-t cell therapies |
| SG11201708360TA (en) | 2015-04-13 | 2017-11-29 | Aduro Biotech Inc | Epidermal growth factor receptor variant iii-mesothelin fusions and methods of using the same |
| HK1250731A1 (zh) | 2015-04-13 | 2019-01-11 | 艾杜罗生物科技公司 | 用於治疗癌症的免疫原性融合蛋白 |
| EP4410318A3 (en) | 2015-06-26 | 2024-10-09 | Cerus Corporation | Cryoprecipitate compositions and methods of preparation thereof |
| ES2972443T3 (es) | 2015-10-23 | 2024-06-12 | Cerus Corp | Plasma pobre en crioprecipitado inactivado para patógenos y métodos de uso del mismo |
| EP3389630B1 (en) | 2015-12-16 | 2023-11-08 | Gritstone bio, Inc. | Neoantigen identification, manufacture, and use |
| WO2018119462A1 (en) | 2016-12-23 | 2018-06-28 | Cerus Corporation | Systems and methods for testing and screening using compound bound substrates |
| CA3055203A1 (en) | 2017-03-03 | 2018-09-07 | Cerus Corporation | Kits and methods for preparing pathogen-inactivated platelet compositions |
| AU2018336988B2 (en) | 2017-09-19 | 2023-06-22 | Advaxis, Inc. | Compositions and methods for lyophilization of bacteria or Listeria strains |
| JP7227237B2 (ja) | 2017-10-10 | 2023-02-21 | グリットストーン バイオ インコーポレイテッド | ホットスポットを利用した新生抗原の特定 |
| CN111630602A (zh) | 2017-11-22 | 2020-09-04 | 磨石肿瘤生物技术公司 | 减少新抗原的接合表位呈递 |
| SG11202006158TA (en) | 2017-12-29 | 2020-07-29 | Cerus Corp | Systems and methods for treating biological fluids |
| CN112074737A (zh) | 2018-03-09 | 2020-12-11 | 阿德瓦希斯公司 | 用于评估李斯特菌菌株的减毒和感染性的组合物和方法 |
| EP3785029A1 (en) | 2018-04-27 | 2021-03-03 | Advaxis, Inc. | Compositions and methods for evaluating potency of listeria-based immunotherapeutics |
| US20210236545A1 (en) * | 2018-08-02 | 2021-08-05 | Suzhou Royaltech Med Co., Ltd | Tumor immunotherapy composition based on antigen-presenting cells activated by attenuated listeria monocytogenes, preparation method therefor and application thereof |
| WO2020263759A2 (en) | 2019-06-22 | 2020-12-30 | Cerus Corporation | Biological fluid treatment systems |
| WO2020264421A1 (en) | 2019-06-28 | 2020-12-30 | Cerus Corporation | System and methods for implementing a biological fluid treatment device |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| US20240093318A1 (en) | 2020-06-23 | 2024-03-21 | The Regents Of The University Of Colorado, A Body Corporate | Method for diagnosing respiratory pathogens and predicting covid-19 related outcomes |
| CN113845589B (zh) * | 2021-08-20 | 2023-04-07 | 扬州大学 | SmcL单克隆抗体、分泌该抗体的杂交瘤细胞株及其应用和竞争ELISA检测方法 |
| CN114250244A (zh) * | 2021-12-14 | 2022-03-29 | 浙江农林大学 | 以重组减毒单増李斯特菌为载体的结肠癌疫苗及制备方法 |
Family Cites Families (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4545987A (en) * | 1983-12-20 | 1985-10-08 | Advanced Genetics Research Institute | Psoralen inactivated double-stranded RNA viral vaccines |
| US5106619A (en) * | 1983-12-20 | 1992-04-21 | Diamond Scientific Co. | Preparation of inactivated viral vaccines |
| US4556556A (en) * | 1984-03-23 | 1985-12-03 | Advanced Genetics Research Institute | Vaccine for the prevention of vesicular stomatitis virus infection |
| US5171568A (en) * | 1984-04-06 | 1992-12-15 | Chiron Corporation | Recombinant herpes simplex gb-gd vaccine |
| US4791062A (en) * | 1985-02-28 | 1988-12-13 | Diamond Scientific Co. | FVR vaccine |
| DE318216T1 (de) | 1987-11-18 | 1990-06-13 | Chiron Corp., Emeryville, Calif. | Nanbv-diagnostika und vakzine. |
| DK189788D0 (da) | 1988-04-07 | 1988-04-07 | Wolf Watz Hans | Vaccine |
| HU225068B1 (en) | 1989-03-17 | 2006-05-29 | Chiron Corp | Process for producing diagnostics and vaccine of nanbh |
| HUT59964A (en) | 1989-05-18 | 1992-07-28 | Chiron Corp | Process for producing new nanbv diagnostica for determining hepatitis c virus |
| US5180819A (en) * | 1989-12-22 | 1993-01-19 | The Trustees Of Columbia University In The City Of New York | Purified myeloblastin, nucleic acid molecule encoding same, and uses thereof |
| US5830702A (en) * | 1990-10-31 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Live, recombinant listeria monocytogenes and production of cytotoxic T-cell response |
| FR2686896B1 (fr) * | 1992-01-31 | 1995-01-06 | Pasteur Institut | Mutant attenue de listeria monocytogenes; souche recombinante de listeria monocytogenes, utilisation comme vecteurs heterologues d'antigenes vaccinal et utilisation comme vaccin ou composition diagnostique. |
| US5399719A (en) * | 1993-06-28 | 1995-03-21 | Steritech, Inc. | Compounds for the photodecontamination of pathogens in blood |
| US5593823A (en) * | 1993-06-28 | 1997-01-14 | Cerus Corporation | Method for inactivating pathogens in blood using photoactivation of 4'-primary amino-substituted psoralens |
| US6051237A (en) * | 1994-11-08 | 2000-04-18 | The Trustees Of The University Of Pennsylvania | Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector |
| US5691132A (en) * | 1994-11-14 | 1997-11-25 | Cerus Corporation | Method for inactivating pathogens in red cell compositions using quinacrine mustard |
| US6682729B1 (en) * | 1995-05-03 | 2004-01-27 | University Of Maryland, Baltimore | Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same |
| US6150170A (en) * | 1998-05-03 | 2000-11-21 | University Of Maryland At Baltimore | Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors for use in the same |
| US5877159A (en) | 1995-05-03 | 1999-03-02 | University Of Maryland At Baltimore | Method for introducing and expressing genes in animal cells and live invasive bacterial vectors for use in the same |
| US6177441B1 (en) * | 1995-06-05 | 2001-01-23 | Cerus Corporation | Treating red blood cell solutions with anti-viral agents |
| WO1996039818A1 (en) | 1995-06-07 | 1996-12-19 | Cerus Corporation | Treating red blood cell solutions with anti-viral agents |
| GB9521568D0 (en) * | 1995-10-20 | 1995-12-20 | Lynxvale Ltd | Delivery of biologically active polypeptides |
| AU1152397A (en) | 1995-12-20 | 1997-07-14 | Board Of Trustees Of The Leland Stanford Junior University | Methods for in vivo t cell activation by antigen-pulsed dendritic cells |
| AU703769B2 (en) * | 1996-01-05 | 1999-04-01 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Mesothelium antigen and methods and kits for targeting it |
| US5843459A (en) * | 1996-01-19 | 1998-12-01 | Human Gene Therapy Research Institute | Differential inactivation of nucleic acids by chemical modification |
| EP0896506A4 (en) * | 1996-03-22 | 2003-06-18 | Univ Yale | METHOD FOR INDUCING IMMUNE RESPONSE ABILITY IN A SUBJECT |
| BR9708387A (pt) * | 1996-03-28 | 2000-01-04 | Genitrix Llc | Processo para vacinação de um mamìfero a um antìgeno selecionado, células patogênica e hospedeira, composição de vacina, ácido nucleico, e, opsonina engenheirada. |
| EP0808897A1 (en) * | 1996-05-21 | 1997-11-26 | I.D.M. Immuno-Designed Molecules | New antigen presenting cells, a process for preparing the same and their use as cellular vaccines |
| IL127912A0 (en) * | 1996-07-10 | 1999-11-30 | Immunex Corp | Method of activating dendritic cells |
| GB9615022D0 (en) | 1996-07-17 | 1996-09-04 | Mini Agriculture & Fisheries | Vaccine preparations |
| US7273753B2 (en) * | 1996-08-02 | 2007-09-25 | Center Of Blood Research | Purification and uses of dendritic cells and monocytes |
| US6194204B1 (en) * | 1996-08-02 | 2001-02-27 | Center For Blood Research, Inc. | Enrichment of dendritic cells from blood |
| DE19635676A1 (de) * | 1996-09-03 | 1998-03-05 | Basf Ag | Feste geschäumte Wirkstoffzubereitungen |
| TW555562B (en) * | 1996-12-27 | 2003-10-01 | Kirin Brewery | Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof |
| US6514987B1 (en) * | 1997-01-06 | 2003-02-04 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| US6093725A (en) * | 1997-01-06 | 2000-07-25 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| AU744089C (en) | 1997-01-06 | 2003-07-31 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| GB9700939D0 (en) | 1997-01-17 | 1997-03-05 | Microbial Technics Limited | Therapy |
| WO1998033386A1 (en) | 1997-01-31 | 1998-08-06 | Vanderbilt University | Method of delivering antigens for vaccination with a live vector |
| AU748074B2 (en) | 1997-07-21 | 2002-05-30 | Cerus Corporation | Method of treating leukocytes, leukocyte compositions and methods of use thereof |
| EP0902086A1 (en) * | 1997-08-22 | 1999-03-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Tuberculosis vaccine |
| US6099848A (en) | 1997-11-18 | 2000-08-08 | The Trustees Of The University Of Pennsylvania | Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use |
| ATE252830T1 (de) | 1997-11-20 | 2003-11-15 | Cerus Corp | Neue psoralene zur inaktivierung von pathogenen |
| DE19754938B4 (de) | 1997-12-11 | 2006-04-20 | Christoph von Dr. Eichel-Streiber | TGC-Verfahren zur Induktion einer zielgerichteten, somatischen Transgenität |
| US6143551A (en) * | 1997-12-29 | 2000-11-07 | Schering Aktiengesellschaft | Delivery of polypeptide-encoding plasmid DNA into the cytosol of macrophages by attenuated listeria suicide bacteria |
| ES2224415T3 (es) * | 1998-01-06 | 2005-03-01 | Cerus Corporation | Metodos para inhibir desactivadores patogenos en materiales biologicos. |
| AU756911B2 (en) | 1998-03-20 | 2003-01-23 | Biopolo S.C.R.L. | Processes for improved presentation of antigens by dendritic cells |
| CA2347067C (en) * | 1998-03-31 | 2013-09-17 | Geron Corporation | Dendritic cell vaccine containing telomerase reverse transcriptase for the treatment of cancer |
| US20020155108A1 (en) * | 1998-05-04 | 2002-10-24 | Biocrystal, Ltd. | Method for ex vivo loading of antigen presenting cells with antigen, and a vaccine comprising the loaded cells |
| US6254863B1 (en) | 1998-08-12 | 2001-07-03 | Loma Linda University | Non-virulent Porphyromonas gingivalis mutant |
| US6004815A (en) * | 1998-08-13 | 1999-12-21 | The Regents Of The University Of California | Bacteria expressing nonsecreted cytolysin as intracellular microbial delivery vehicles to eukaryotic cells |
| GB9918283D0 (en) | 1999-08-03 | 1999-10-06 | Int Centre Genetic Eng & Bio | Hsv vaccines |
| AU7856100A (en) | 1999-10-04 | 2001-05-10 | Vion Pharmaceuticals, Inc. | Methods for treating solid tumors with irradiation and bacteria |
| DE19949594A1 (de) * | 1999-10-14 | 2001-04-26 | Deutsches Krebsforsch | Rekombinante attenuierte Listerien zur Immuntherapie |
| US20030077263A1 (en) * | 1999-10-29 | 2003-04-24 | Immunex Corporation | Method of activating dendritic cells |
| GB0007150D0 (en) * | 2000-03-24 | 2000-05-17 | Lamellar Therapeutics Limited | Immunotherapeutic methods and compositions |
| AU2001255196A1 (en) | 2000-03-29 | 2001-10-08 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing immunogenicity of antigens |
| US6855320B2 (en) * | 2000-03-29 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity |
| MXPA02010826A (es) * | 2000-05-04 | 2006-03-09 | Harvard College | Compuestos y metodos para el tratamiento y la prevencion de infeccion bacteriana. |
| CA2460014A1 (en) * | 2000-09-21 | 2002-03-28 | The Regents Of The University Of California | Spas-1 cancer antigen |
| US7405076B2 (en) * | 2000-11-14 | 2008-07-29 | Universite Libre De Bruxelles | Generation and use of dendritic cells |
| CA2434256A1 (en) * | 2000-12-21 | 2003-07-31 | David Cook | Methods for inactivation of pathogens in biological materials |
| US6783765B2 (en) * | 2001-03-23 | 2004-08-31 | Council Of Scientific And Industrial Research | Process for the preparation of a vaccine for the treatment of tuberculosis and other intracellular infections diseases and the vaccine produced by the process |
| WO2002083879A2 (en) * | 2001-04-02 | 2002-10-24 | Alimentary Health Limited | Immunotherapy based on dendritic cells |
| US7566568B2 (en) * | 2001-04-27 | 2009-07-28 | Istituto Superiore Di Sanita | Method for generating highly active human dendritic cells from peripheral blood mononuclear cells |
| US20040022761A1 (en) * | 2001-05-11 | 2004-02-05 | Banchereau Jacques F | Compositions and methods for producing antigen-presenting cells |
| WO2003012085A1 (en) * | 2001-07-30 | 2003-02-13 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Antigen presenting cells, method for their preparation and their use for cancer vaccines |
| US7413869B2 (en) * | 2002-04-05 | 2008-08-19 | Dendreon Corporation | Method for determining potency of antigenic presenting cell based vaccines |
| US7425449B2 (en) * | 2002-04-30 | 2008-09-16 | The Regents Of The University Of California | Site specific Listeria integration vectors and methods for using the same |
| JP2005527240A (ja) * | 2002-05-29 | 2005-09-15 | ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 弱毒リステリア種とこれを使用する方法 |
| US20040009194A1 (en) * | 2002-06-21 | 2004-01-15 | Jean-Marie Andrieu | Methods, and compositions for a therapeutic antigen presenting cell vaccine for treatment of immunodeficiency virus |
| AU2002950473A0 (en) | 2002-07-26 | 2002-09-12 | Commonwealth Scientific And Industrial Research Organisation | Expression system |
| ES2382332T3 (es) * | 2003-02-06 | 2012-06-07 | Aduro Biotech | Listeria atenuada para entrar en células no fagocíticas, vacunas que comprenden esta listeria y métodos de uso de las mismas |
| AU2004224425B2 (en) * | 2003-02-06 | 2010-06-24 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| US7695725B2 (en) | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| AU2004281834A1 (en) * | 2003-10-15 | 2005-04-28 | Cerus Corporation | Listeria-based EphA2 vaccines |
| US20050175630A1 (en) * | 2003-12-23 | 2005-08-11 | Eyal Raz | Immunogenic compositions and methods of use thereof |
| US7842289B2 (en) * | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| EP1708741B1 (en) | 2003-12-24 | 2016-03-30 | Aduro Biotech | Recombinant nucleic acid molecules encoding fusion proteins comprising antigens and bacterial secretory signal polypeptides, expression cassettes, and bacteria, and methods of use thereof |
| WO2005067460A2 (en) | 2003-12-24 | 2005-07-28 | Medimmune, Inc. | Epha2 vaccines |
| WO2005092372A2 (en) | 2004-02-06 | 2005-10-06 | Cerus Corporation | Modified bacillus anthracis vaccine compositions and methods of use thereof |
| US20070031457A1 (en) * | 2004-02-06 | 2007-02-08 | Dubensky Thomas W Jr | Modified Bacillus anthracis, vaccine compositions and methods of use thereof |
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2004
- 2004-02-06 ES ES04749316T patent/ES2382332T3/es not_active Expired - Lifetime
- 2004-02-06 CA CA2515369A patent/CA2515369C/en not_active Expired - Fee Related
- 2004-02-06 US US10/773,792 patent/US7691393B2/en active Active
- 2004-02-06 WO PCT/US2004/003429 patent/WO2004110481A2/en not_active Ceased
- 2004-02-06 AT AT04749316T patent/ATE552843T1/de active
- 2004-02-06 JP JP2006532281A patent/JP4545151B2/ja not_active Expired - Fee Related
- 2004-02-06 DK DK04749316.8T patent/DK1592441T3/da active
- 2004-02-06 AU AU2004246999A patent/AU2004246999B2/en not_active Ceased
- 2004-02-06 PT PT04749316T patent/PT1592441E/pt unknown
- 2004-02-06 EP EP04749316A patent/EP1592441B1/en not_active Expired - Lifetime
- 2004-02-06 MX MXPA05008342A patent/MXPA05008342A/es active IP Right Grant
- 2004-02-06 KR KR1020057014538A patent/KR101192652B1/ko not_active Expired - Fee Related
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2007
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Also Published As
| Publication number | Publication date |
|---|---|
| PT1592441E (pt) | 2012-05-21 |
| US8287883B2 (en) | 2012-10-16 |
| US20040228877A1 (en) | 2004-11-18 |
| KR101192652B1 (ko) | 2012-10-19 |
| AU2004246999A1 (en) | 2004-12-23 |
| HK1082187A1 (en) | 2006-06-02 |
| EP1592441A2 (en) | 2005-11-09 |
| JP4545151B2 (ja) | 2010-09-15 |
| JP2007125040A (ja) | 2007-05-24 |
| ES2382332T3 (es) | 2012-06-07 |
| US7691393B2 (en) | 2010-04-06 |
| CA2515369A1 (en) | 2004-12-23 |
| EP1592441B1 (en) | 2012-04-11 |
| JP2007503846A (ja) | 2007-03-01 |
| CA2515369C (en) | 2015-03-31 |
| US20110201092A1 (en) | 2011-08-18 |
| ATE552843T1 (de) | 2012-04-15 |
| KR20050105460A (ko) | 2005-11-04 |
| WO2004110481A3 (en) | 2005-03-03 |
| WO2004110481A2 (en) | 2004-12-23 |
| AU2004246999B2 (en) | 2010-06-10 |
| MXPA05008342A (es) | 2006-02-28 |
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