IL257056A - Methods for producing alpha-galactosidase a compositions - Google Patents

Methods for producing alpha-galactosidase a compositions

Info

Publication number
IL257056A
IL257056A IL257056A IL25705618A IL257056A IL 257056 A IL257056 A IL 257056A IL 257056 A IL257056 A IL 257056A IL 25705618 A IL25705618 A IL 25705618A IL 257056 A IL257056 A IL 257056A
Authority
IL
Israel
Prior art keywords
methods
galactosidase
compositions
producing alpha
alpha galactosidase
Prior art date
Application number
IL257056A
Other languages
Hebrew (he)
Other versions
IL257056B (en
Original Assignee
Shire Human Genetic Therapies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Human Genetic Therapies filed Critical Shire Human Genetic Therapies
Publication of IL257056A publication Critical patent/IL257056A/en
Publication of IL257056B publication Critical patent/IL257056B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01022Alpha-galactosidase (3.2.1.22)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Obesity (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)

Abstract

The invention provides methods of treating alpha galactosidase A deficiency. Dosage forms, methods of administration, and methods of analyzing human alpha galactosidase A are also included.
IL257056A 2002-04-25 2018-01-21 Methods for producing alpha-galactosidase a compositions IL257056B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37558402P 2002-04-25 2002-04-25
PCT/US2003/013063 WO2003090695A2 (en) 2002-04-25 2003-04-25 TREATMENT OF α-GALACTOSIDASE A DEFICIENCY

Publications (2)

Publication Number Publication Date
IL257056A true IL257056A (en) 2018-06-28
IL257056B IL257056B (en) 2021-03-25

Family

ID=29270665

Family Applications (4)

Application Number Title Priority Date Filing Date
IL16475704A IL164757A0 (en) 2002-04-25 2004-10-21 Method for analyzing an alpha-galactosidase a preparation
IL220043A IL220043B (en) 2002-04-25 2012-05-29 Methods for producing α-galactosidase a compositions and uses thereof
IL257056A IL257056B (en) 2002-04-25 2018-01-21 Methods for producing alpha-galactosidase a compositions
IL280818A IL280818B (en) 2002-04-25 2021-02-11 Methods for producing alpha-galactosidase a compositions

Family Applications Before (2)

Application Number Title Priority Date Filing Date
IL16475704A IL164757A0 (en) 2002-04-25 2004-10-21 Method for analyzing an alpha-galactosidase a preparation
IL220043A IL220043B (en) 2002-04-25 2012-05-29 Methods for producing α-galactosidase a compositions and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL280818A IL280818B (en) 2002-04-25 2021-02-11 Methods for producing alpha-galactosidase a compositions

Country Status (13)

Country Link
US (6) US20040071686A1 (en)
EP (2) EP1503788B1 (en)
JP (5) JP5570677B2 (en)
AT (1) ATE514430T1 (en)
AU (2) AU2003228722B2 (en)
BR (2) BR122017016940B8 (en)
CA (1) CA2483270C (en)
DK (1) DK1503788T3 (en)
ES (1) ES2367257T3 (en)
HK (1) HK1073608A1 (en)
IL (4) IL164757A0 (en)
NZ (1) NZ536361A (en)
WO (1) WO2003090695A2 (en)

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WO2009024977A2 (en) 2007-08-20 2009-02-26 Protalix Ltd. Saccharide-containing protein conjugates and uses thereof
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US9194011B2 (en) 2009-11-17 2015-11-24 Protalix Ltd. Stabilized alpha-galactosidase and uses thereof
US20120230974A1 (en) * 2009-11-17 2012-09-13 Protalix Ltd Alkaline alpha galactosidase for the treatment of fabry disease
ES2896060T3 (en) * 2010-06-25 2022-02-23 Shire Human Genetic Therapies Methods and compositions for CNS administration of arylsulfatase A
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Also Published As

Publication number Publication date
US20170216411A1 (en) 2017-08-03
US20160184409A1 (en) 2016-06-30
EP1503788A2 (en) 2005-02-09
HK1073608A1 (en) 2005-10-14
BRPI0309665B8 (en) 2021-05-25
US20060177433A1 (en) 2006-08-10
JP2018016630A (en) 2018-02-01
JP2016180003A (en) 2016-10-13
CA2483270C (en) 2015-03-31
US7833742B2 (en) 2010-11-16
IL280818B (en) 2021-12-01
IL164757A0 (en) 2005-12-18
JP6492139B2 (en) 2019-03-27
JP2012140431A (en) 2012-07-26
US20040071686A1 (en) 2004-04-15
WO2003090695A3 (en) 2004-05-06
AU2009217430A1 (en) 2009-10-15
IL257056B (en) 2021-03-25
JP5570677B2 (en) 2014-08-13
CA2483270A1 (en) 2003-11-06
IL280818A (en) 2021-04-29
BRPI0309665B1 (en) 2019-07-16
EP2361631A1 (en) 2011-08-31
AU2003228722A1 (en) 2003-11-10
BR122017016940B1 (en) 2020-11-10
EP1503788B1 (en) 2011-06-29
US10245304B2 (en) 2019-04-02
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US11116823B2 (en) 2021-09-14
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IL220043A0 (en) 2012-06-28
JP2005538941A (en) 2005-12-22
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US20190255156A1 (en) 2019-08-22
BR0309665A (en) 2005-08-16
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JP2014196343A (en) 2014-10-16
AU2003228722B2 (en) 2009-06-25
US20110002908A1 (en) 2011-01-06
JP6225224B2 (en) 2017-11-01
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