DK157757C - Analogifremgangsmaade til fremstilling af terapeutisk virksomme pyrimidooe1,6-aaaindol-5-eddikesyrederivater eller salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af terapeutisk virksomme pyrimidooe1,6-aaaindol-5-eddikesyrederivater eller salte deraf

Info

Publication number
DK157757C
DK157757C DK095081A DK95081A DK157757C DK 157757 C DK157757 C DK 157757C DK 095081 A DK095081 A DK 095081A DK 95081 A DK95081 A DK 95081A DK 157757 C DK157757 C DK 157757C
Authority
DK
Denmark
Prior art keywords
salts
pyrimidooe
indol
aaa
analogy
Prior art date
Application number
DK095081A
Other languages
Danish (da)
English (en)
Other versions
DK95081A (da
DK157757B (da
Inventor
Ulrich Renner
Knut A Jaeggi
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK95081A publication Critical patent/DK95081A/da
Publication of DK157757B publication Critical patent/DK157757B/da
Application granted granted Critical
Publication of DK157757C publication Critical patent/DK157757C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Gasification And Melting Of Waste (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Dental Preparations (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DK095081A 1980-03-04 1981-03-03 Analogifremgangsmaade til fremstilling af terapeutisk virksomme pyrimidooe1,6-aaaindol-5-eddikesyrederivater eller salte deraf DK157757C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH170380 1980-03-04
CH170380 1980-03-04

Publications (3)

Publication Number Publication Date
DK95081A DK95081A (da) 1981-09-05
DK157757B DK157757B (da) 1990-02-12
DK157757C true DK157757C (da) 1990-07-16

Family

ID=4216625

Family Applications (1)

Application Number Title Priority Date Filing Date
DK095081A DK157757C (da) 1980-03-04 1981-03-03 Analogifremgangsmaade til fremstilling af terapeutisk virksomme pyrimidooe1,6-aaaindol-5-eddikesyrederivater eller salte deraf

Country Status (24)

Country Link
EP (1) EP0035474B1 (xx)
JP (1) JPS56138188A (xx)
KR (5) KR850000045B1 (xx)
AT (1) ATE13673T1 (xx)
AU (1) AU544236B2 (xx)
CA (1) CA1161433A (xx)
CY (1) CY1340A (xx)
DD (1) DD156599A5 (xx)
DE (1) DE3170801D1 (xx)
DK (1) DK157757C (xx)
ES (3) ES8301989A1 (xx)
FI (1) FI74007C (xx)
GB (1) GB2070608B (xx)
GR (1) GR74470B (xx)
HK (1) HK80086A (xx)
HU (1) HU186385B (xx)
IE (1) IE50985B1 (xx)
IL (1) IL62249A (xx)
KE (1) KE3646A (xx)
MY (1) MY8600361A (xx)
NO (1) NO156012C (xx)
NZ (1) NZ196393A (xx)
PT (1) PT72597B (xx)
ZA (1) ZA811398B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444768A (en) * 1980-03-04 1984-04-24 Ciba-Geigy Corporation Pyrimido[1,6-a]indoles, pharmaceutical preparations containing them, and methods of treating pain and inflammation with them
DE3270406D1 (en) * 1981-08-03 1986-05-15 Ciba Geigy Ag Amidines, process for their preparation, pharmaceutical compounds containing them and their use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307234A (en) * 1978-09-11 1981-12-22 American Home Products Corp. Pyrimido[1,6-a]indole derivatives

Also Published As

Publication number Publication date
NO810719L (no) 1981-09-07
NZ196393A (en) 1983-12-16
IL62249A (en) 1985-08-30
KR850000044B1 (ko) 1985-02-14
DK95081A (da) 1981-09-05
FI74007C (fi) 1987-12-10
DD156599A5 (de) 1982-09-08
GR74470B (xx) 1984-06-28
ES8305763A1 (es) 1983-04-16
KR850000045B1 (ko) 1985-02-14
MY8600361A (en) 1986-12-31
KR850000060B1 (ko) 1985-02-15
PT72597B (en) 1982-03-26
AU544236B2 (en) 1985-05-23
AU6801681A (en) 1981-09-10
JPS56138188A (en) 1981-10-28
ZA811398B (en) 1982-04-28
CA1161433A (en) 1984-01-31
ATE13673T1 (de) 1985-06-15
IE50985B1 (en) 1986-09-03
ES499973A0 (es) 1983-01-16
KR850000062B1 (ko) 1985-02-15
GB2070608A (en) 1981-09-09
ES514590A0 (es) 1983-04-16
KR830005226A (ko) 1983-08-03
GB2070608B (en) 1983-11-02
HK80086A (en) 1986-10-31
JPH0338273B2 (xx) 1991-06-10
ES509645A0 (es) 1984-01-16
EP0035474A1 (de) 1981-09-09
ES8402301A1 (es) 1984-01-16
EP0035474B1 (de) 1985-06-05
KR850000061B1 (ko) 1985-02-15
HU186385B (en) 1985-07-29
CY1340A (en) 1987-01-16
DE3170801D1 (en) 1985-07-11
NO156012C (no) 1987-07-08
FI810647L (fi) 1981-09-05
KE3646A (en) 1986-07-11
NO156012B (no) 1987-03-30
IE810455L (en) 1981-09-04
FI74007B (fi) 1987-08-31
PT72597A (en) 1981-04-01
ES8301989A1 (es) 1983-01-16
DK157757B (da) 1990-02-12

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
PBP Patent lapsed