DK154607C - Fremgangsmaade til fremstilling af en laegemiddelform til oral administration af ergotalkaloider - Google Patents

Fremgangsmaade til fremstilling af en laegemiddelform til oral administration af ergotalkaloider

Info

Publication number
DK154607C
DK154607C DK529879A DK529879A DK154607C DK 154607 C DK154607 C DK 154607C DK 529879 A DK529879 A DK 529879A DK 529879 A DK529879 A DK 529879A DK 154607 C DK154607 C DK 154607C
Authority
DK
Denmark
Prior art keywords
ergotal
kaloids
preparing
procedure
oral administration
Prior art date
Application number
DK529879A
Other languages
Danish (da)
English (en)
Other versions
DK529879A (da
DK154607B (da
Inventor
Joachim Franz
Ludwig Patt
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK529879A publication Critical patent/DK529879A/da
Publication of DK154607B publication Critical patent/DK154607B/da
Application granted granted Critical
Publication of DK154607C publication Critical patent/DK154607C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/48Ergoline derivatives, e.g. lysergic acid, ergotamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5015Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK529879A 1978-12-21 1979-12-12 Fremgangsmaade til fremstilling af en laegemiddelform til oral administration af ergotalkaloider DK154607C (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
CH1301978 1978-12-21
CH1302178 1978-12-21
CH1301978 1978-12-21
CH1302178 1978-12-21
CH56779 1979-01-19
CH56679 1979-01-19
CH56679 1979-01-19
CH56779 1979-01-19

Publications (3)

Publication Number Publication Date
DK529879A DK529879A (da) 1980-06-22
DK154607B DK154607B (da) 1988-12-05
DK154607C true DK154607C (da) 1989-06-05

Family

ID=27427929

Family Applications (1)

Application Number Title Priority Date Filing Date
DK529879A DK154607C (da) 1978-12-21 1979-12-12 Fremgangsmaade til fremstilling af en laegemiddelform til oral administration af ergotalkaloider

Country Status (23)

Country Link
AT (1) AT372279B (sv)
AU (1) AU534051B2 (sv)
CA (1) CA1139222A (sv)
CH (1) CH642259A5 (sv)
CY (1) CY1330A (sv)
DE (1) DE2950154A1 (sv)
DK (1) DK154607C (sv)
FI (1) FI793888A (sv)
FR (1) FR2444463A1 (sv)
GB (1) GB2038181B (sv)
HK (1) HK37986A (sv)
HU (1) HU182577B (sv)
IE (1) IE49323B1 (sv)
IL (1) IL59003A (sv)
IT (1) IT1164029B (sv)
KE (1) KE3617D (sv)
MY (1) MY8500129A (sv)
NL (1) NL187229C (sv)
NZ (1) NZ192457A (sv)
PH (1) PH25178A (sv)
PT (1) PT70614A (sv)
SE (1) SE442265B (sv)
WO (1) WO1980001242A1 (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0064485B1 (en) * 1981-04-27 1985-07-24 Aktiebolaget Hässle New pharmaceutical preparation
US4366145A (en) * 1981-06-24 1982-12-28 Sandoz, Inc. Soft gelatin capsule with a liquid ergot alkaloid center fill solution and method of preparation
HU192050B (en) * 1983-04-22 1987-05-28 Sandoz Ag Process for production of medical preparative containing co-dergocrin and one piridin-dicarbonic acid diesthertype calcium-antagonist
DE3413955A1 (de) * 1983-04-22 1984-10-25 Sandoz-Patent-GmbH, 7850 Lörrach Pharmazeutisches praeparat enthaltend co-dergocrine und einen calcium-antagonisten
HU198844B (en) * 1984-06-14 1989-12-28 Sandoz Ag Process for producing new galenic pharmaceutical composition ensuring retarded release of active ingredient
GB8426922D0 (en) * 1984-10-24 1984-11-28 Sandoz Ltd Galenic formulation
AT388101B (de) * 1985-02-05 1989-05-10 Sandoz Ag Verfahren zur herstellung einer pharmazeutischen zusammensetzung zur oralen verabreichung mit kontrollierter wirkstofffreisetzung
CN1003978B (zh) * 1987-09-05 1989-04-26 广州陈李济药厂 一种补脾益肠丸的制备工艺

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3432593A (en) * 1963-09-18 1969-03-11 Key Pharm Inc Delayed and sustained release type pharmaceutical preparation
DE2528257C2 (de) * 1974-07-04 1986-02-13 Sandoz-Patent-GmbH, 7850 Lörrach Neue galenische Zubereitung
DE2546577B2 (de) * 1975-10-17 1981-04-02 Sandoz-Patent-GmbH, 7850 Lörrach Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden

Also Published As

Publication number Publication date
IT7951153A0 (it) 1979-12-20
AU5403179A (en) 1980-06-26
FR2444463B1 (sv) 1983-02-25
HK37986A (en) 1986-05-30
DE2950154A1 (de) 1980-07-10
DE2950154C2 (sv) 1989-05-11
NL7909105A (nl) 1980-06-24
KE3617D (en) 1986-04-18
PT70614A (fr) 1980-01-01
HU182577B (en) 1984-02-28
SE7910227L (sv) 1980-06-22
CH642259A5 (de) 1984-04-13
AU534051B2 (en) 1984-01-05
GB2038181B (en) 1983-05-11
SE442265B (sv) 1985-12-16
WO1980001242A1 (en) 1980-06-26
CA1139222A (en) 1983-01-11
IT1164029B (it) 1987-04-08
GB2038181A (en) 1980-07-23
CY1330A (en) 1986-06-27
NZ192457A (en) 1983-06-17
FR2444463A1 (fr) 1980-07-18
DK529879A (da) 1980-06-22
IE792471L (en) 1980-06-21
DK154607B (da) 1988-12-05
ATA803679A (de) 1983-02-15
PH25178A (en) 1991-03-27
IL59003A (en) 1982-12-31
AT372279B (de) 1983-09-26
FI793888A (fi) 1980-06-22
MY8500129A (en) 1985-12-31
IE49323B1 (en) 1985-09-18
NL187229C (nl) 1991-07-16

Similar Documents

Publication Publication Date Title
DK153440C (da) Fremgangsmaade til fremstilling af et nasalt farmaceutisk ergotpeptidalkaloid-praeparat
DK153773C (da) Fremgangsmaade til fremstillling af et farmaceutisk praeparat til forlaenget frigoerelse af et laegemiddel
DK562276A (da) Fremgangsmaade til fremstilling af en farmaceutisk administrationsform
RO75336A (ro) Procedeu pentru prepararea unei forme farmaceutice destinate administrarii transdermale a clonidinei
SE433804B (sv) Forfarande for framstellning av en farmaceutisk lekemedelsberedning i kapselform med retardeffekt
DK162877C (da) Depotplaster til indgift af et laegemiddel
FI65914B (fi) Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
ES503132A0 (es) Un procedimiento de preparacion de una composicion farmaceu-tica de un esteroide
DK143221C (da) Fremgangsmaade til fremstilling af et laegemiddel i folieform til oral eller topisk anvendelse
DK664387D0 (da) Fremgangsmaade til fremstilling af et anti-inflammatorisk farmaceutisk praeparat
DK588476A (da) Fremgangsmade til fremstilling af et oralt administrerbart farmaceutisk preparat
DK160739C (da) Fremgangsmaade til fremstilling af et stabilt prostaglandinindeholdende praeparat til laegemiddelanvendelse
DK271677A (da) Fremgangsmade til fremstilling af et farmaceutisk indsetningspreparat
DK528879A (da) Fremgangsmaade til fremstilling af et farmaceutisk praeparat indeholdende isosorbiddinitrat
DK152173C (da) Fremgangsmaade til fremstilling af en farmaceutisk zinkkompleksoploesning til oral indgift
DK152333C (da) Indretning til oral indgivelse til droevtyggere
DK302880A (da) Fremgangsmaade til fremstilling af et farmaceutisk praeparat indeholdende en 3-amino1-aryl-2-pyrazolin
DK645788A (da) Anvendelse af ergolinderivater til fremstilling af et farmaceutisk praeparat
DK203879A (da) Fremgangsmaade til fremstilling af en farmaceutisk doseringskomponent
NO146044C (no) Fremgangsmaate for fremstilling av et farmasoeytisk insulin-preparat for rektal bruk
DK154607C (da) Fremgangsmaade til fremstilling af en laegemiddelform til oral administration af ergotalkaloider
DK98076A (da) Fremgangsmade til fremstilling af et farmaceutisk preparat
DK352578A (da) Fremgangsmaade til fremstilling af et farmaceutisk praeparat
DK7679A (da) Fremgangsmaade til fremstilling af et prostaglandinholdigt praeparat
DK523277A (da) Fremgangsmaade til fremstilling af et farmaceutisk praeparat med protraheret virkning

Legal Events

Date Code Title Description
PBP Patent lapsed