DK1545574T3 - Fremgangsmåde til rensning af polypeptider ved simuleret moving-bed-chromatografi - Google Patents

Fremgangsmåde til rensning af polypeptider ved simuleret moving-bed-chromatografi

Info

Publication number
DK1545574T3
DK1545574T3 DK03754547.2T DK03754547T DK1545574T3 DK 1545574 T3 DK1545574 T3 DK 1545574T3 DK 03754547 T DK03754547 T DK 03754547T DK 1545574 T3 DK1545574 T3 DK 1545574T3
Authority
DK
Denmark
Prior art keywords
polypeptides
cleaning
procedure
simulated moving
bed chromatography
Prior art date
Application number
DK03754547.2T
Other languages
English (en)
Inventor
Marc Bisschops
Maarten Pennings
Jörg P Thömmes
Alan M Sonnenfeld
John P Pieracci
Lynn Conley
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Application granted granted Critical
Publication of DK1545574T3 publication Critical patent/DK1545574T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B01D15/185—Simulated moving beds characterized by the components to be separated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/468—Flow patterns using more than one column involving switching between different column configurations
DK03754547.2T 2002-09-13 2003-09-12 Fremgangsmåde til rensning af polypeptider ved simuleret moving-bed-chromatografi DK1545574T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41050602P 2002-09-13 2002-09-13
PCT/US2003/028809 WO2004024284A2 (en) 2002-09-13 2003-09-12 Method of purifying polypeptides by simulated moving bed chromatography

Publications (1)

Publication Number Publication Date
DK1545574T3 true DK1545574T3 (da) 2014-09-08

Family

ID=31994146

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03754547.2T DK1545574T3 (da) 2002-09-13 2003-09-12 Fremgangsmåde til rensning af polypeptider ved simuleret moving-bed-chromatografi

Country Status (11)

Country Link
US (2) US7220356B2 (da)
EP (1) EP1545574B8 (da)
JP (1) JP2006507249A (da)
CN (2) CN102050865B (da)
AU (2) AU2003272368C1 (da)
CA (1) CA2498725C (da)
DK (1) DK1545574T3 (da)
HK (1) HK1077228A1 (da)
NZ (2) NZ539297A (da)
SI (1) SI1545574T1 (da)
WO (1) WO2004024284A2 (da)

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Also Published As

Publication number Publication date
US20070215534A1 (en) 2007-09-20
AU2009200842A1 (en) 2009-03-26
AU2003272368C1 (en) 2009-07-23
EP1545574B1 (en) 2014-08-20
CN102050865B (zh) 2014-03-12
CN102050865A (zh) 2011-05-11
EP1545574B8 (en) 2014-09-24
WO2004024284A2 (en) 2004-03-25
WO2004024284A3 (en) 2004-09-23
US8608960B2 (en) 2013-12-17
CN1777435B (zh) 2011-01-12
SI1545574T1 (sl) 2014-10-30
NZ539297A (en) 2008-04-30
AU2003272368A1 (en) 2004-04-30
AU2009200842B2 (en) 2011-06-02
CA2498725C (en) 2014-07-08
US20040241878A1 (en) 2004-12-02
US7220356B2 (en) 2007-05-22
EP1545574A2 (en) 2005-06-29
NZ563078A (en) 2009-07-31
AU2003272368B2 (en) 2008-12-04
CN1777435A (zh) 2006-05-24
CA2498725A1 (en) 2004-03-25
HK1077228A1 (en) 2006-02-10
JP2006507249A (ja) 2006-03-02
EP1545574A4 (en) 2006-07-19

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