DK1527065T3 - Fremgangsmåde til fremstilling af (S) - 3 methylamino-1-(thien-2-yl) propan-1-o1 - Google Patents
Fremgangsmåde til fremstilling af (S) - 3 methylamino-1-(thien-2-yl) propan-1-o1Info
- Publication number
- DK1527065T3 DK1527065T3 DK03766383T DK03766383T DK1527065T3 DK 1527065 T3 DK1527065 T3 DK 1527065T3 DK 03766383 T DK03766383 T DK 03766383T DK 03766383 T DK03766383 T DK 03766383T DK 1527065 T3 DK1527065 T3 DK 1527065T3
- Authority
- DK
- Denmark
- Prior art keywords
- thien
- propan
- preparation
- methylamino
- ylpropionitrile
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10235206A DE10235206A1 (de) | 2002-08-01 | 2002-08-01 | Verfahren zur Herstellung von (S)-3-Methylmino-1-(thien-2-yl)propan-1-ol |
PCT/EP2003/008492 WO2004013123A1 (de) | 2002-08-01 | 2003-07-31 | Verfahren zur herstellung von (s)-3-methylamino-1-(thien-2-yl)propan-1-ol |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1527065T3 true DK1527065T3 (da) | 2007-03-26 |
Family
ID=30469326
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03766383T DK1527065T3 (da) | 2002-08-01 | 2003-07-31 | Fremgangsmåde til fremstilling af (S) - 3 methylamino-1-(thien-2-yl) propan-1-o1 |
Country Status (11)
Country | Link |
---|---|
US (1) | US7435563B2 (da) |
EP (1) | EP1527065B1 (da) |
JP (1) | JP4528620B2 (da) |
CN (1) | CN1301989C (da) |
AT (1) | ATE346061T1 (da) |
AU (1) | AU2003251677A1 (da) |
CA (1) | CA2493451C (da) |
DE (2) | DE10235206A1 (da) |
DK (1) | DK1527065T3 (da) |
ES (1) | ES2278203T3 (da) |
WO (1) | WO2004013123A1 (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004055194A1 (en) * | 2002-12-16 | 2004-07-01 | Council Of Scientific And Industrial Research | Chemoenzymatic process for stereoselective preparation of r and s enatiomers of 2-hydroxy-3-(2-thienyl) propanenitrile |
DE102004004719A1 (de) * | 2004-01-29 | 2005-08-18 | Basf Ag | Verfahren zur Herstellung von enantiomerenreinen Aminoalkoholen |
US20050197503A1 (en) * | 2004-03-05 | 2005-09-08 | Boehringer Ingelheim International Gmbh | Process for the preparation of N-alkyl-N-methyl-3-hydroxy-3-(2-thienyl)-propylamines |
CA2656128A1 (en) | 2006-07-03 | 2008-01-10 | Ranbaxy Laboratories Limited | Process for the preparation of enantiomerically pure salts of n-methyl-3(1-naphthaleneoxy)-3-(2-thienyl)propanamine |
CN101657438A (zh) | 2006-12-22 | 2010-02-24 | 斯索恩有限公司 | 制备度洛西汀和相关化合物的方法 |
US8288141B2 (en) * | 2008-08-27 | 2012-10-16 | Codexis, Inc. | Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
ES2560459T3 (es) | 2008-08-27 | 2016-02-19 | Codexis, Inc. | Polipéptidos cetorreductasa para la producción de una 3-aril-3-hidroxipropanamina a partir de una 3-aril-3-cetopropanamina |
WO2010123067A1 (ja) * | 2009-04-23 | 2010-10-28 | 株式会社カネカ | (s)-1-置換プロパン-1-オール誘導体の製造方法 |
EP2558455B1 (en) | 2010-04-13 | 2017-08-09 | KRKA, D.D., Novo Mesto | Synthesis of duloxetine and/or pharmaceutically acceptable salts thereof |
CN105758970B (zh) * | 2016-05-17 | 2018-05-15 | 泰山医学院 | 一种气相色谱法检测3-甲胺基-1,2-丙二醇纯度的方法 |
CN106244505B (zh) * | 2016-10-09 | 2019-08-27 | 北京工商大学 | 吡咯伯克霍尔德氏菌的应用及其产脂肪酶的方法 |
DE102017104480A1 (de) | 2017-03-03 | 2018-09-06 | Nordmark Arzneimittel Gmbh & Co. Kg | Wässrige Lösung von Burlulipase umfassend Kalziumionen |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR880007433A (ko) * | 1986-12-22 | 1988-08-27 | 메리 앤 터커 | 3-아릴옥시-3-치환된 프로판아민 |
CA2042346A1 (en) * | 1990-05-17 | 1991-11-18 | Michael Alexander Staszak | Chiral synthesis of 1-aryl-3-aminopropan-1-ols |
US5254737A (en) * | 1990-09-17 | 1993-10-19 | Texaco Chemical Company | Continuous preparation of secondary amines from nitriles using a two-step process |
US5136078A (en) * | 1991-02-26 | 1992-08-04 | Eli Lilly And Company | Synthesis of b-cyanohydrins |
US5362886A (en) * | 1993-10-12 | 1994-11-08 | Eli Lilly And Company | Asymmetric synthesis |
UA53679C2 (uk) * | 1996-12-16 | 2003-02-17 | Басф Акцієнгезелльшафт | Заміщені піразол-3-ілбензазоли, спосіб їх одержання (варіанти), гербіцидний засіб та спосіб його одержання, засіб для десикації і/або дефоліації рослин та спосіб його одержання, спосіб боротьби з небажаним ростом рослин та спосіб десикації і/або дефоліації рослин |
JP2002513023A (ja) * | 1998-04-29 | 2002-05-08 | ビーエーエスエフ アクチェンゲゼルシャフト | 置換(4−ブロモピラゾール−3−イル)ベンゾアゾール |
DE19931847A1 (de) * | 1999-07-09 | 2001-01-11 | Basf Ag | Immobilisierte Lipase |
JP2004520039A (ja) * | 2001-01-22 | 2004-07-08 | カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ | 3−ヒドロキシ−3−フェニルプロパンニトリルの立体選択的調製 |
-
2002
- 2002-08-01 DE DE10235206A patent/DE10235206A1/de not_active Withdrawn
-
2003
- 2003-07-31 US US10/522,888 patent/US7435563B2/en not_active Expired - Fee Related
- 2003-07-31 AU AU2003251677A patent/AU2003251677A1/en not_active Abandoned
- 2003-07-31 EP EP03766383A patent/EP1527065B1/de not_active Expired - Lifetime
- 2003-07-31 JP JP2004525403A patent/JP4528620B2/ja not_active Expired - Fee Related
- 2003-07-31 WO PCT/EP2003/008492 patent/WO2004013123A1/de active IP Right Grant
- 2003-07-31 CA CA2493451A patent/CA2493451C/en not_active Expired - Fee Related
- 2003-07-31 ES ES03766383T patent/ES2278203T3/es not_active Expired - Lifetime
- 2003-07-31 AT AT03766383T patent/ATE346061T1/de not_active IP Right Cessation
- 2003-07-31 CN CNB038185105A patent/CN1301989C/zh not_active Expired - Fee Related
- 2003-07-31 DE DE50305771T patent/DE50305771D1/de not_active Expired - Lifetime
- 2003-07-31 DK DK03766383T patent/DK1527065T3/da active
Also Published As
Publication number | Publication date |
---|---|
US20050245749A1 (en) | 2005-11-03 |
US7435563B2 (en) | 2008-10-14 |
DE10235206A1 (de) | 2004-02-19 |
CN1301989C (zh) | 2007-02-28 |
JP4528620B2 (ja) | 2010-08-18 |
CA2493451C (en) | 2011-02-22 |
EP1527065B1 (de) | 2006-11-22 |
CA2493451A1 (en) | 2004-02-12 |
WO2004013123A1 (de) | 2004-02-12 |
CN1671687A (zh) | 2005-09-21 |
ATE346061T1 (de) | 2006-12-15 |
DE50305771D1 (de) | 2007-01-04 |
JP2006507234A (ja) | 2006-03-02 |
ES2278203T3 (es) | 2007-08-01 |
EP1527065A1 (de) | 2005-05-04 |
AU2003251677A1 (en) | 2004-02-23 |
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