DK150472C - Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive cycloalkylmethylphenyleddikesyrederivater eller farmaceutisk acceptablesalte deraf - Google Patents
Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive cycloalkylmethylphenyleddikesyrederivater eller farmaceutisk acceptablesalte derafInfo
- Publication number
- DK150472C DK150472C DK148478A DK148478A DK150472C DK 150472 C DK150472 C DK 150472C DK 148478 A DK148478 A DK 148478A DK 148478 A DK148478 A DK 148478A DK 150472 C DK150472 C DK 150472C
- Authority
- DK
- Denmark
- Prior art keywords
- cycloylmethylphenyledic
- racemic
- analogue
- preparation
- acetic acid
- Prior art date
Links
- 150000001242 acetic acid derivatives Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
- C07C251/60—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3890677 | 1977-04-05 | ||
| JP3890777A JPS6034539B2 (ja) | 1977-04-05 | 1977-04-05 | オキシム置換フエニル酢酸誘導体及びその製法 |
| JP3890777 | 1977-04-05 | ||
| JP3890677A JPS584699B2 (ja) | 1977-04-05 | 1977-04-05 | 置換フエニル酢酸誘導体及びその製法 |
| JP6846877A JPS6034540B2 (ja) | 1977-06-10 | 1977-06-10 | オキシム置換フエニル酢酸誘導体の製造法 |
| JP6846877 | 1977-06-10 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK148478A DK148478A (da) | 1978-10-06 |
| DK150472B DK150472B (da) | 1987-03-09 |
| DK150472C true DK150472C (da) | 1987-12-14 |
Family
ID=27289981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK148478A DK150472C (da) | 1977-04-05 | 1978-04-04 | Analogifremgangsmaade til fremstilling af racemiske eller optisk aktive cycloalkylmethylphenyleddikesyrederivater eller farmaceutisk acceptablesalte deraf |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4161538A (hu) |
| BE (1) | BE869097A (hu) |
| CA (1) | CA1113113A (hu) |
| CH (1) | CH633515A5 (hu) |
| DE (1) | DE2814556C2 (hu) |
| DK (1) | DK150472C (hu) |
| ES (1) | ES468578A1 (hu) |
| FR (1) | FR2395256A1 (hu) |
| GB (1) | GB1580113A (hu) |
| NL (1) | NL190519C (hu) |
| SE (1) | SE437261B (hu) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD141422A5 (de) * | 1978-01-27 | 1980-04-30 | Schering Ag | Verfahren zur herstellung von phenylessigsaeure-derivaten |
| DE2861078D1 (en) * | 1978-07-21 | 1981-12-03 | Schering Ag | Indan-1-carboxylic acid derivatives,process for their preparation and pharmaceutical preparations containing these compounds |
| CH645539A5 (de) * | 1980-06-09 | 1984-10-15 | Sankyo Co | Antiinflammatorische mittel fuer die aeusserliche anwendung. |
| US4423068A (en) * | 1982-07-14 | 1983-12-27 | Syntex (U.S.A.) Inc. | (3.2.0) Bicycloheptanone oxime ethers with therapeutic properties |
| JPS59196839A (ja) * | 1983-04-21 | 1984-11-08 | Sankyo Co Ltd | フエニル酢酸誘導体 |
| JPS6038323A (ja) * | 1983-08-10 | 1985-02-27 | Sankyo Co Ltd | 眼科用消炎剤 |
| SE8400239D0 (sv) * | 1984-01-19 | 1984-01-19 | Pharmacia Ab | Nya arylettiksyraderivat |
| JPS61268621A (ja) * | 1985-05-21 | 1986-11-28 | Sankyo Co Ltd | シロツプ製剤 |
| US5179124A (en) * | 1988-01-25 | 1993-01-12 | University Of Iowa Research Foundation | Anti-inflammatory for use in external and internal eye inflammations |
| US4968718A (en) * | 1988-01-25 | 1990-11-06 | University Of Iowa Research Foundation | Topically effective, nonsteroidal drug for use in external and internal eye inflammations |
| JP3775796B2 (ja) * | 1993-10-06 | 2006-05-17 | ニコックス エス エイ | 抗炎症活性及び／又は鎮痛活性を有する硝酸エステル類及びそれらの製造方法 |
| IT1282660B1 (it) * | 1996-02-21 | 1998-03-31 | Chemi Spa | Processo per produrre l'acido (t) 2- 4-2-oxociclopentilmetil) fenilpropionico ed i suoi sali |
| IT1308633B1 (it) | 1999-03-02 | 2002-01-09 | Nicox Sa | Nitrossiderivati. |
| KR100695334B1 (ko) * | 2000-02-10 | 2007-03-15 | 니뽄 세키유 가가쿠 가부시키가이샤 | 2-치환 프로피온산의 제조방법 |
| IT1318673B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Farmaci per le disfunzioni sessuali. |
| IT1318674B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Faramaci per l'incontinenza. |
| MY144587A (en) * | 2001-06-21 | 2011-10-14 | Kao Corp | Polishing composition |
| ITMI20020773A1 (it) * | 2002-04-11 | 2003-10-13 | Nicox Sa | Farmaci per il trattamento dell'artrite |
| TW200827343A (en) * | 2006-09-11 | 2008-07-01 | Fuji Yakuhin Co Ltd | Novel phenylacetic acid derivative |
| JP5390883B2 (ja) | 2009-02-26 | 2014-01-15 | 国立大学法人 熊本大学 | ロキソプロフェン誘導体及びそれを含有する医薬 |
| WO2014167509A2 (en) * | 2013-04-10 | 2014-10-16 | Shasun Pharmaceuticals Limited | Loxoprofen polymorphs and process for preparation of the same |
| EP2926810A1 (en) | 2014-03-31 | 2015-10-07 | Sanovel Ilac Sanayi ve Ticaret A.S. | Oral liquid pharmaceutical formulations of loxoprofen |
| EP2926832A1 (en) | 2014-03-31 | 2015-10-07 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical formulations of loxoprofen for topical use |
| EP2939666A1 (en) | 2014-04-29 | 2015-11-04 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical formulations of loxoprofen |
| EP2959889A1 (en) | 2014-06-25 | 2015-12-30 | Sanovel Ilac Sanayi ve Ticaret A.S. | Orally disintegrating formulations of loxoprofen |
| EA201692424A1 (ru) | 2014-06-30 | 2017-04-28 | Сановель Илач Санайи Ве Тиджарет А.Ш. | Комбинации локсопрофена и агониста рецепторов гамма-аминомасляной кислоты |
| WO2016046189A1 (en) | 2014-09-24 | 2016-03-31 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Loxoprofen and antispastic drug combinations |
| WO2016156354A1 (en) | 2015-03-31 | 2016-10-06 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Pharmaceutical composition comprising loxoprofen, glucosamine, chondroitin, hyaluronic acid for joint and cartilage disorders |
| CN109467506B (zh) * | 2017-09-07 | 2021-12-07 | 江苏瑞科医药科技有限公司 | 一种取代苯乙酸衍生物的制备方法 |
| CN108997119B (zh) * | 2018-07-13 | 2020-10-20 | 湖北迅达药业股份有限公司 | 洛索洛芬钠合成工艺中缩合反应中间体的纯化方法 |
| CN112851500B (zh) * | 2021-02-10 | 2022-11-29 | 南京知和医药科技有限公司 | S-洛索洛芬衍生物及其制备方法、药物组合物和用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
| US4008269A (en) * | 1970-05-05 | 1977-02-15 | William H. Rorer, Inc. | Phenylacetic acids |
| US3894080A (en) * | 1970-05-05 | 1975-07-08 | Rorer Inc William H | Phenylacetic acids |
| US3825587A (en) * | 1970-05-05 | 1974-07-23 | Rorer Inc William H | Substituted phenylacetic acid compounds |
| US3864384A (en) * | 1970-05-05 | 1975-02-04 | Rorer Inc William H | Substituted phenylacetic acid compounds |
| GB1364075A (en) * | 1971-09-04 | 1974-08-21 | Logeais Labor Jacques | Phenylacetic acid derivatives process for their preparation and therapeutic compositions |
| FR2243680B2 (hu) * | 1973-09-17 | 1977-01-28 | Logeais Labor Jacques |
-
1978
- 1978-03-10 US US05/885,527 patent/US4161538A/en not_active Expired - Lifetime
- 1978-04-04 DE DE2814556A patent/DE2814556C2/de not_active Expired
- 1978-04-04 DK DK148478A patent/DK150472C/da not_active IP Right Cessation
- 1978-04-05 CA CA300,479A patent/CA1113113A/en not_active Expired
- 1978-04-05 NL NLAANVRAGE7803644,A patent/NL190519C/xx not_active IP Right Cessation
- 1978-04-05 CH CH367678A patent/CH633515A5/de not_active IP Right Cessation
- 1978-04-05 FR FR7810126A patent/FR2395256A1/fr active Granted
- 1978-04-05 ES ES468578A patent/ES468578A1/es not_active Expired
- 1978-04-05 GB GB13355/78A patent/GB1580113A/en not_active Expired
- 1978-04-05 SE SE7803848A patent/SE437261B/sv not_active IP Right Cessation
- 1978-07-18 BE BE189363A patent/BE869097A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2395256B1 (hu) | 1982-12-10 |
| CH633515A5 (de) | 1982-12-15 |
| DK148478A (da) | 1978-10-06 |
| DE2814556C2 (de) | 1987-03-12 |
| BE869097A (fr) | 1979-01-18 |
| FR2395256A1 (fr) | 1979-01-19 |
| SE7803848L (sv) | 1978-10-06 |
| GB1580113A (en) | 1980-11-26 |
| NL7803644A (nl) | 1978-10-09 |
| ES468578A1 (es) | 1979-09-16 |
| DK150472B (da) | 1987-03-09 |
| NL190519C (nl) | 1994-04-05 |
| US4161538A (en) | 1979-07-17 |
| NL190519B (nl) | 1993-11-01 |
| CA1113113A (en) | 1981-11-24 |
| DE2814556A1 (de) | 1978-10-12 |
| SE437261B (sv) | 1985-02-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed | ||
| PUP | Patent expired |