DK148824C - Analogifremgangsmaade til fremstilling af farmakologisk virksomme n-(2-morpholinoethyl)-benzamider eller syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af farmakologisk virksomme n-(2-morpholinoethyl)-benzamider eller syreadditionssalte deraf

Info

Publication number
DK148824C
DK148824C DK51677A DK51677A DK148824C DK 148824 C DK148824 C DK 148824C DK 51677 A DK51677 A DK 51677A DK 51677 A DK51677 A DK 51677A DK 148824 C DK148824 C DK 148824C
Authority
DK
Denmark
Prior art keywords
benzamides
morpholinoethyl
analogue
preparation
acid addition
Prior art date
Application number
DK51677A
Other languages
Danish (da)
English (en)
Other versions
DK51677A (da
DK148824B (da
Inventor
Willy Burkard
Pierre-Charles Wyss
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK51677A publication Critical patent/DK51677A/da
Publication of DK148824B publication Critical patent/DK148824B/da
Application granted granted Critical
Publication of DK148824C publication Critical patent/DK148824C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK51677A 1976-02-16 1977-02-08 Analogifremgangsmaade til fremstilling af farmakologisk virksomme n-(2-morpholinoethyl)-benzamider eller syreadditionssalte deraf DK148824C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT107076A AT345842B (de) 1976-02-16 1976-02-16 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxyden und salzen
AT107076 1976-02-16

Publications (3)

Publication Number Publication Date
DK51677A DK51677A (da) 1977-08-17
DK148824B DK148824B (da) 1985-10-14
DK148824C true DK148824C (da) 1986-04-21

Family

ID=3505951

Family Applications (1)

Application Number Title Priority Date Filing Date
DK51677A DK148824C (da) 1976-02-16 1977-02-08 Analogifremgangsmaade til fremstilling af farmakologisk virksomme n-(2-morpholinoethyl)-benzamider eller syreadditionssalte deraf

Country Status (28)

Country Link
JP (1) JPS52100476A (xx)
AR (2) AR214307A1 (xx)
AT (5) AT345842B (xx)
AU (1) AU506427B2 (xx)
BE (1) BE851422A (xx)
CA (1) CA1076112A (xx)
CH (5) CH623317A5 (xx)
DE (1) DE2706179C2 (xx)
DK (1) DK148824C (xx)
ES (4) ES455907A1 (xx)
FI (1) FI65426C (xx)
FR (1) FR2340940A1 (xx)
GB (1) GB1512194A (xx)
GR (1) GR62413B (xx)
HR (1) HRP930495B1 (xx)
IE (1) IE44482B1 (xx)
IL (1) IL51406A (xx)
LU (2) LU76771A1 (xx)
MC (1) MC1136A1 (xx)
NL (2) NL179382C (xx)
NO (2) NO148417C (xx)
NZ (1) NZ183316A (xx)
PH (1) PH12847A (xx)
PT (1) PT66195B (xx)
SE (1) SE426822B (xx)
SI (1) SI7710060A8 (xx)
YU (1) YU39983B (xx)
ZA (1) ZA77746B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4829506B2 (ja) * 2004-02-17 2011-12-07 石原産業株式会社 チオアミド系化合物又はその塩、並びにそれらを含有するサイトカイン産生抑制剤
ATE414694T1 (de) * 2005-05-03 2008-12-15 Bayer Cropscience Sa Neue heterocyclylethylbenzamid-derivate
RU2570898C2 (ru) * 2014-03-27 2015-12-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский химико-технологический университет имени Д.И. Менделеева (РХТУ им. Д.И. Менделеева)" Способ получения n-[2-(морфолин-4-ил)этил]-4-хлорбензамида (варианты)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH451142A (de) * 1965-01-19 1968-05-15 Sandoz Ag Verfahren zur Herstellung neuer basisch substituierter Benzoesäureamide
FR1501846A (fr) * 1966-09-26 1967-11-18 Bellon Labor Sa Roger Procédé amélioré pour la préparation des thioamides
US3787419A (en) * 1971-07-01 1974-01-22 American Home Prod N-substituted-alpha,alpha,alpha-trifluoro-m-toluamides

Also Published As

Publication number Publication date
IL51406A0 (en) 1977-04-29
CA1076112A (en) 1980-04-22
DK51677A (da) 1977-08-17
ES467449A1 (es) 1978-10-16
HRP930495B1 (en) 1996-10-31
ES455907A1 (es) 1978-05-01
NL179382B (nl) 1986-04-01
ATA107076A (de) 1978-02-15
IE44482B1 (en) 1981-12-16
AT345842B (de) 1978-10-10
AT349481B (de) 1979-04-10
SE7701669L (sv) 1977-08-17
NL930082I2 (nl) 1994-08-16
LU88300I2 (de) 1994-09-09
YU6077A (en) 1983-01-21
MC1136A1 (fr) 1977-11-18
NL930082I1 (nl) 1993-09-16
AT349479B (de) 1979-04-10
NZ183316A (en) 1979-04-26
BE851422A (fr) 1977-08-16
SE426822B (sv) 1983-02-14
FI65426C (fi) 1984-05-10
ZA77746B (en) 1977-12-28
JPS6215547B2 (xx) 1987-04-08
FR2340940B1 (xx) 1981-01-09
LU76771A1 (xx) 1978-04-13
GR62413B (en) 1979-04-11
ATA25778A (de) 1978-09-15
AR212554A1 (es) 1978-07-31
NO1994008I1 (no) 1994-08-03
IL51406A (en) 1979-12-30
DK148824B (da) 1985-10-14
AU506427B2 (en) 1980-01-03
AR214307A1 (es) 1979-05-31
PH12847A (en) 1979-09-12
GB1512194A (en) 1978-05-24
ATA25878A (de) 1978-09-15
NO148417C (no) 1983-10-12
DE2706179C2 (de) 1984-02-02
CH623576A5 (en) 1981-06-15
PT66195B (fr) 1979-01-17
IE44482L (en) 1977-08-16
NL7701144A (nl) 1977-08-18
NO148417B (no) 1983-06-27
AT349480B (de) 1979-04-10
ATA25678A (de) 1978-09-15
CH623577A5 (en) 1981-06-15
FR2340940A1 (fr) 1977-09-09
NL179382C (nl) 1986-09-01
CH623317A5 (en) 1981-05-29
PT66195A (fr) 1977-03-01
FI65426B (fi) 1984-01-31
YU39983B (en) 1985-06-30
DE2706179A1 (de) 1977-08-18
FI770356A (xx) 1977-08-17
CH622787A5 (en) 1981-04-30
AU2109977A (en) 1978-07-13
ES467455A1 (es) 1978-10-16
AT349482B (de) 1979-04-10
SI7710060A8 (en) 1996-12-31
ATA25578A (de) 1978-09-15
CH622786A5 (en) 1981-04-30
JPS52100476A (en) 1977-08-23
NO770488L (no) 1977-08-17
ES467448A1 (es) 1978-10-16

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Legal Events

Date Code Title Description
CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 1993 00022, 930609

CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 1993 00022, 930609

PUP Patent expired