ES455907A1 - Un procedimiento para la preparacion de derivados de benza- mida. - Google Patents

Un procedimiento para la preparacion de derivados de benza- mida.

Info

Publication number
ES455907A1
ES455907A1 ES455907A ES455907A ES455907A1 ES 455907 A1 ES455907 A1 ES 455907A1 ES 455907 A ES455907 A ES 455907A ES 455907 A ES455907 A ES 455907A ES 455907 A1 ES455907 A1 ES 455907A1
Authority
ES
Spain
Prior art keywords
benzamides
halogen
denotes
benzoylaziridines
haloethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES455907A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES455907A1 publication Critical patent/ES455907A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un procedimiento para la preparación de derivados de benzamida, de la fórmula general: **(fórmula)** en donde X representa un átomo de halógeno o un grupo trifluorometílico o alquílico de C{sub,3-4} o Y representa un átomo de hidrógeno o de halógeno o un grupo nitro; y sus N-óxidos y sales de adición de ácido, caracterizado porque comprende hacer reaccionar N-(2-aminoetil)-morfolino con un ácido.
ES455907A 1976-02-16 1977-02-15 Un procedimiento para la preparacion de derivados de benza- mida. Expired ES455907A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT107076A AT345842B (de) 1976-02-16 1976-02-16 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxyden und salzen

Publications (1)

Publication Number Publication Date
ES455907A1 true ES455907A1 (es) 1978-05-01

Family

ID=3505951

Family Applications (4)

Application Number Title Priority Date Filing Date
ES455907A Expired ES455907A1 (es) 1976-02-16 1977-02-15 Un procedimiento para la preparacion de derivados de benza- mida.
ES467448A Expired ES467448A1 (es) 1976-02-16 1978-03-01 Un procedimiento para la preparacion de derivados de benza- mida.
ES467455A Expired ES467455A1 (es) 1976-02-16 1978-03-01 Un procedimiento para la preparacion de derivados de benza- mida.
ES467449A Expired ES467449A1 (es) 1976-02-16 1978-03-01 Un procedimiento para la preparacion de derivados de benza- mida.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES467448A Expired ES467448A1 (es) 1976-02-16 1978-03-01 Un procedimiento para la preparacion de derivados de benza- mida.
ES467455A Expired ES467455A1 (es) 1976-02-16 1978-03-01 Un procedimiento para la preparacion de derivados de benza- mida.
ES467449A Expired ES467449A1 (es) 1976-02-16 1978-03-01 Un procedimiento para la preparacion de derivados de benza- mida.

Country Status (28)

Country Link
JP (1) JPS52100476A (es)
AR (2) AR214307A1 (es)
AT (5) AT345842B (es)
AU (1) AU506427B2 (es)
BE (1) BE851422A (es)
CA (1) CA1076112A (es)
CH (5) CH623317A5 (es)
DE (1) DE2706179C2 (es)
DK (1) DK148824C (es)
ES (4) ES455907A1 (es)
FI (1) FI65426C (es)
FR (1) FR2340940A1 (es)
GB (1) GB1512194A (es)
GR (1) GR62413B (es)
HR (1) HRP930495B1 (es)
IE (1) IE44482B1 (es)
IL (1) IL51406A (es)
LU (2) LU76771A1 (es)
MC (1) MC1136A1 (es)
NL (2) NL179382C (es)
NO (2) NO148417C (es)
NZ (1) NZ183316A (es)
PH (1) PH12847A (es)
PT (1) PT66195B (es)
SE (1) SE426822B (es)
SI (1) SI7710060A8 (es)
YU (1) YU39983B (es)
ZA (1) ZA77746B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4829506B2 (ja) * 2004-02-17 2011-12-07 石原産業株式会社 チオアミド系化合物又はその塩、並びにそれらを含有するサイトカイン産生抑制剤
ATE414694T1 (de) * 2005-05-03 2008-12-15 Bayer Cropscience Sa Neue heterocyclylethylbenzamid-derivate
RU2570898C2 (ru) * 2014-03-27 2015-12-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский химико-технологический университет имени Д.И. Менделеева (РХТУ им. Д.И. Менделеева)" Способ получения n-[2-(морфолин-4-ил)этил]-4-хлорбензамида (варианты)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH451142A (de) * 1965-01-19 1968-05-15 Sandoz Ag Verfahren zur Herstellung neuer basisch substituierter Benzoesäureamide
FR1501846A (fr) * 1966-09-26 1967-11-18 Bellon Labor Sa Roger Procédé amélioré pour la préparation des thioamides
US3787419A (en) * 1971-07-01 1974-01-22 American Home Prod N-substituted-alpha,alpha,alpha-trifluoro-m-toluamides

Also Published As

Publication number Publication date
IL51406A0 (en) 1977-04-29
CA1076112A (en) 1980-04-22
DK51677A (da) 1977-08-17
ES467449A1 (es) 1978-10-16
HRP930495B1 (en) 1996-10-31
NL179382B (nl) 1986-04-01
ATA107076A (de) 1978-02-15
IE44482B1 (en) 1981-12-16
AT345842B (de) 1978-10-10
AT349481B (de) 1979-04-10
SE7701669L (sv) 1977-08-17
NL930082I2 (nl) 1994-08-16
LU88300I2 (de) 1994-09-09
YU6077A (en) 1983-01-21
MC1136A1 (fr) 1977-11-18
NL930082I1 (nl) 1993-09-16
AT349479B (de) 1979-04-10
NZ183316A (en) 1979-04-26
BE851422A (fr) 1977-08-16
SE426822B (sv) 1983-02-14
FI65426C (fi) 1984-05-10
ZA77746B (en) 1977-12-28
JPS6215547B2 (es) 1987-04-08
FR2340940B1 (es) 1981-01-09
LU76771A1 (es) 1978-04-13
GR62413B (en) 1979-04-11
ATA25778A (de) 1978-09-15
AR212554A1 (es) 1978-07-31
NO1994008I1 (no) 1994-08-03
IL51406A (en) 1979-12-30
DK148824B (da) 1985-10-14
AU506427B2 (en) 1980-01-03
AR214307A1 (es) 1979-05-31
PH12847A (en) 1979-09-12
DK148824C (da) 1986-04-21
GB1512194A (en) 1978-05-24
ATA25878A (de) 1978-09-15
NO148417C (no) 1983-10-12
DE2706179C2 (de) 1984-02-02
CH623576A5 (en) 1981-06-15
PT66195B (fr) 1979-01-17
IE44482L (en) 1977-08-16
NL7701144A (nl) 1977-08-18
NO148417B (no) 1983-06-27
AT349480B (de) 1979-04-10
ATA25678A (de) 1978-09-15
CH623577A5 (en) 1981-06-15
FR2340940A1 (fr) 1977-09-09
NL179382C (nl) 1986-09-01
CH623317A5 (en) 1981-05-29
PT66195A (fr) 1977-03-01
FI65426B (fi) 1984-01-31
YU39983B (en) 1985-06-30
DE2706179A1 (de) 1977-08-18
FI770356A (es) 1977-08-17
CH622787A5 (en) 1981-04-30
AU2109977A (en) 1978-07-13
ES467455A1 (es) 1978-10-16
AT349482B (de) 1979-04-10
SI7710060A8 (en) 1996-12-31
ATA25578A (de) 1978-09-15
CH622786A5 (en) 1981-04-30
JPS52100476A (en) 1977-08-23
NO770488L (no) 1977-08-17
ES467448A1 (es) 1978-10-16

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