DK1487840T3 - Krystallinsk polymorf form af irinotecan hydrochlorid - Google Patents
Krystallinsk polymorf form af irinotecan hydrochloridInfo
- Publication number
- DK1487840T3 DK1487840T3 DK03743335T DK03743335T DK1487840T3 DK 1487840 T3 DK1487840 T3 DK 1487840T3 DK 03743335 T DK03743335 T DK 03743335T DK 03743335 T DK03743335 T DK 03743335T DK 1487840 T3 DK1487840 T3 DK 1487840T3
- Authority
- DK
- Denmark
- Prior art keywords
- polymorphic form
- irinotecan hydrochloride
- crystalline polymorphic
- crystalline
- irinotecan
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36068402P | 2002-03-01 | 2002-03-01 | |
| PCT/EP2003/001948 WO2003074527A1 (en) | 2002-03-01 | 2003-02-26 | Crystalline polymorphic form of irinotecan hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1487840T3 true DK1487840T3 (da) | 2007-07-16 |
Family
ID=27789001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03743335T DK1487840T3 (da) | 2002-03-01 | 2003-02-26 | Krystallinsk polymorf form af irinotecan hydrochlorid |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1487840B1 (xx) |
| JP (1) | JP2005525367A (xx) |
| KR (1) | KR20040091083A (xx) |
| CN (1) | CN1276923C (xx) |
| AR (1) | AR038618A1 (xx) |
| AT (1) | ATE364610T1 (xx) |
| AU (1) | AU2003215594A1 (xx) |
| BR (1) | BR0308133A (xx) |
| CA (1) | CA2477926A1 (xx) |
| DE (1) | DE60314378T2 (xx) |
| DK (1) | DK1487840T3 (xx) |
| ES (1) | ES2287495T3 (xx) |
| HK (1) | HK1075044A1 (xx) |
| IL (1) | IL163820A0 (xx) |
| MX (1) | MXPA04008484A (xx) |
| NO (1) | NO20044138L (xx) |
| NZ (1) | NZ534999A (xx) |
| PE (1) | PE20030923A1 (xx) |
| PL (1) | PL372318A1 (xx) |
| PT (1) | PT1487840E (xx) |
| RU (1) | RU2300535C2 (xx) |
| TW (1) | TWI270374B (xx) |
| WO (1) | WO2003074527A1 (xx) |
| ZA (1) | ZA200406927B (xx) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0407791A (pt) | 2003-02-25 | 2006-02-14 | Yakult Honsa Kk | método para preparação de polimorfismo de cloridrato de irinotecan |
| ES2245891B1 (es) * | 2004-07-09 | 2006-11-16 | Clinmet S.L. | "metodo para la obtencion de un excipiente universal para la administracion oral de principios activos farmaceuticos y composiciones de excipientes resultantes del metodo". |
| ME01495B (me) | 2004-12-21 | 2014-04-20 | Sigma Tau Ind Farmaceuti | STEREOSELEKT IVNI POSTUPAK l KRISTALNI OBLICI KAMPTOTECINA |
| CA2591081C (en) | 2005-02-07 | 2014-10-28 | Fermion Oy | Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin |
| US7767813B2 (en) | 2005-02-08 | 2010-08-03 | Fermion Oy | Preparation method |
| US7662964B2 (en) | 2005-02-08 | 2010-02-16 | Fermion Oy | Process for producing [1,4′] bipiperidinyl-1′-carbonyl chloride or hydrochloride thereof |
| JP5119153B2 (ja) * | 2005-09-20 | 2013-01-16 | シノファーム シンガポール ピーティーイー，リミテッド | イリノテカン塩酸塩の新規結晶形 |
| CN101318964B (zh) * | 2007-06-07 | 2010-12-15 | 上海迪赛诺医药发展有限公司 | 盐酸伊立替康新晶型及其制备方法 |
| FR2918279B1 (fr) * | 2007-07-05 | 2010-10-22 | Aventis Pharma Sa | Combinaisons antitumorales contenant un agent inhibiteur de vegf et de l'irinotecan |
| IT1391757B1 (it) * | 2008-11-11 | 2012-01-27 | Antibioticos Spa | Irinotecan cloridrato cristallino e metodi per la sua preparazione |
| CN101659667B (zh) * | 2009-09-07 | 2011-11-02 | 重庆泰濠制药有限公司 | 一种盐酸伊立替康的纯化方法 |
| US8546573B2 (en) | 2009-11-18 | 2013-10-01 | Cadila Healthcare Limited | Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate |
| JO3283B1 (ar) | 2011-04-26 | 2018-09-16 | Sanofi Sa | تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI) |
| CN102866126B (zh) * | 2011-07-05 | 2016-03-23 | 重庆华邦制药有限公司 | 一种定量测定化合物中晶型比例的方法 |
| CN102311443B (zh) * | 2011-08-24 | 2014-07-16 | 上海北卡医药技术有限公司 | 盐酸伊立替康的新晶型及其制备方法 |
| RU2529831C2 (ru) * | 2012-11-30 | 2014-09-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский университет дружбы народов" (РУДН) | Способ лечения рака толстой кишки |
| EP3170005B1 (en) | 2014-07-18 | 2019-04-10 | Sanofi | Method for predicting the outcome of a treatment with aflibercept of a patient suspected to suffer from a cancer |
| KR102293907B1 (ko) * | 2015-06-30 | 2021-08-26 | 한미약품 주식회사 | 이리노테칸 함유 경구용 고형제제 및 그 제조방법 |
| KR102066402B1 (ko) * | 2017-12-22 | 2020-01-15 | 대화제약 주식회사 | 이리노테칸 또는 그의 약제학적으로 허용가능한 염을 포함하는 경구투여용 약제학적 조성물 |
| US10919905B2 (en) * | 2019-05-16 | 2021-02-16 | Scinopharm Taiwan, Ltd. | Polymorphism for irinotecan free base |
-
2003
- 2003-02-26 ES ES03743335T patent/ES2287495T3/es not_active Expired - Lifetime
- 2003-02-26 DK DK03743335T patent/DK1487840T3/da active
- 2003-02-26 EP EP03743335A patent/EP1487840B1/en not_active Expired - Lifetime
- 2003-02-26 CN CNB038072726A patent/CN1276923C/zh not_active Expired - Fee Related
- 2003-02-26 BR BR0308133-8A patent/BR0308133A/pt not_active IP Right Cessation
- 2003-02-26 MX MXPA04008484A patent/MXPA04008484A/es not_active Application Discontinuation
- 2003-02-26 PT PT03743335T patent/PT1487840E/pt unknown
- 2003-02-26 NZ NZ534999A patent/NZ534999A/en unknown
- 2003-02-26 JP JP2003572995A patent/JP2005525367A/ja not_active Withdrawn
- 2003-02-26 AT AT03743335T patent/ATE364610T1/de not_active IP Right Cessation
- 2003-02-26 KR KR10-2004-7013621A patent/KR20040091083A/ko not_active Application Discontinuation
- 2003-02-26 WO PCT/EP2003/001948 patent/WO2003074527A1/en active IP Right Grant
- 2003-02-26 CA CA002477926A patent/CA2477926A1/en not_active Abandoned
- 2003-02-26 PL PL03372318A patent/PL372318A1/xx not_active Application Discontinuation
- 2003-02-26 DE DE60314378T patent/DE60314378T2/de not_active Expired - Fee Related
- 2003-02-26 AU AU2003215594A patent/AU2003215594A1/en not_active Abandoned
- 2003-02-26 RU RU2004129307/04A patent/RU2300535C2/ru not_active IP Right Cessation
- 2003-02-26 IL IL16382003A patent/IL163820A0/xx unknown
- 2003-02-27 TW TW092104194A patent/TWI270374B/zh not_active IP Right Cessation
- 2003-02-28 PE PE2003000196A patent/PE20030923A1/es not_active Application Discontinuation
- 2003-02-28 AR ARP030100656A patent/AR038618A1/es unknown
-
2004
- 2004-08-31 ZA ZA200406927A patent/ZA200406927B/en unknown
- 2004-09-29 NO NO20044138A patent/NO20044138L/no not_active Application Discontinuation
-
2005
- 2005-08-22 HK HK05107303A patent/HK1075044A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PE20030923A1 (es) | 2003-10-29 |
| KR20040091083A (ko) | 2004-10-27 |
| WO2003074527A1 (en) | 2003-09-12 |
| NZ534999A (en) | 2007-03-30 |
| PT1487840E (pt) | 2007-09-11 |
| TWI270374B (en) | 2007-01-11 |
| EP1487840B1 (en) | 2007-06-13 |
| CN1276923C (zh) | 2006-09-27 |
| TW200303753A (en) | 2003-09-16 |
| CN1642958A (zh) | 2005-07-20 |
| BR0308133A (pt) | 2005-01-04 |
| ES2287495T3 (es) | 2007-12-16 |
| NO20044138L (no) | 2004-11-29 |
| IL163820A0 (en) | 2005-12-18 |
| RU2300535C2 (ru) | 2007-06-10 |
| MXPA04008484A (es) | 2004-12-06 |
| AR038618A1 (es) | 2005-01-19 |
| ATE364610T1 (de) | 2007-07-15 |
| JP2005525367A (ja) | 2005-08-25 |
| HK1075044A1 (en) | 2005-12-02 |
| CA2477926A1 (en) | 2003-09-12 |
| AU2003215594A1 (en) | 2003-09-16 |
| ZA200406927B (en) | 2006-06-28 |
| PL372318A1 (en) | 2005-07-11 |
| EP1487840A1 (en) | 2004-12-22 |
| DE60314378T2 (de) | 2008-02-28 |
| RU2004129307A (ru) | 2005-04-10 |
| DE60314378D1 (en) | 2007-07-26 |
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