DK148744C - Analogifremgangsmaade til fremstilling af den enkelte isomere eller en isomerblanding af spiro-(1,3-dioxolan-4,3') quinuclidiner eller farmaceutisk acceptable syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af den enkelte isomere eller en isomerblanding af spiro-(1,3-dioxolan-4,3') quinuclidiner eller farmaceutisk acceptable syreadditionssalte deraf

Info

Publication number
DK148744C
DK148744C DK507276A DK507276A DK148744C DK 148744 C DK148744 C DK 148744C DK 507276 A DK507276 A DK 507276A DK 507276 A DK507276 A DK 507276A DK 148744 C DK148744 C DK 148744C
Authority
DK
Denmark
Prior art keywords
isomer
quinuclidines
dioxolan
spiro
analogue
Prior art date
Application number
DK507276A
Other languages
Danish (da)
English (en)
Other versions
DK507276A (da
DK148744B (da
Inventor
Sasson Cohen
Abraham Fisher
Original Assignee
Mundipharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mundipharma Ag filed Critical Mundipharma Ag
Publication of DK507276A publication Critical patent/DK507276A/da
Priority to DK281985A priority Critical patent/DK281985A/da
Publication of DK148744B publication Critical patent/DK148744B/da
Application granted granted Critical
Publication of DK148744C publication Critical patent/DK148744C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK507276A 1975-11-11 1976-11-10 Analogifremgangsmaade til fremstilling af den enkelte isomere eller en isomerblanding af spiro-(1,3-dioxolan-4,3') quinuclidiner eller farmaceutisk acceptable syreadditionssalte deraf DK148744C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK281985A DK281985A (da) 1975-11-11 1985-06-21 Analogifremgangsmaade til fremstilling af 2,2-diphenyl-spiro-(1,3-dioxolan-4,3')quinuclidin eller farmaceutisk acceptable syreadditionssalte deraf

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL48452A IL48452A (en) 1975-11-11 1975-11-11 Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them
IL4845275 1975-11-11

Publications (3)

Publication Number Publication Date
DK507276A DK507276A (da) 1977-05-12
DK148744B DK148744B (da) 1985-09-16
DK148744C true DK148744C (da) 1986-02-03

Family

ID=11048545

Family Applications (1)

Application Number Title Priority Date Filing Date
DK507276A DK148744C (da) 1975-11-11 1976-11-10 Analogifremgangsmaade til fremstilling af den enkelte isomere eller en isomerblanding af spiro-(1,3-dioxolan-4,3') quinuclidiner eller farmaceutisk acceptable syreadditionssalte deraf

Country Status (20)

Country Link
US (1) US4104397A (ja)
JP (1) JPS5277092A (ja)
AR (2) AR213102A1 (ja)
AT (1) AT356652B (ja)
AU (1) AU507660B2 (ja)
BE (1) BE848228A (ja)
CA (1) CA1071629A (ja)
CH (1) CH626085A5 (ja)
DE (1) DE2650845A1 (ja)
DK (1) DK148744C (ja)
ES (2) ES453161A1 (ja)
FI (1) FI60015C (ja)
FR (1) FR2331343A1 (ja)
GB (1) GB1542494A (ja)
IL (1) IL48452A (ja)
MX (1) MX4395E (ja)
NL (1) NL7612426A (ja)
NO (1) NO145618C (ja)
NZ (1) NZ182555A (ja)
ZA (1) ZA766662B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2454056A1 (fr) * 1979-03-15 1980-11-07 Geissmann Robert Cheminee cinetique pouvant etre utilisee comme rotissoire
EP0189370A3 (de) * 1985-01-16 1988-01-27 Sandoz Ag Spiro-dioxolane, -dithiolane und -oxothiolane
JPS61167130A (ja) * 1985-01-17 1986-07-28 Nissan Motor Co Ltd 内燃機関の吸気装置
US4855290A (en) * 1985-05-10 1989-08-08 State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research Derivatives of quinuclidine
ES2074441T3 (es) * 1987-10-05 1995-09-16 Yamanouchi Pharma Co Ltd Compuestos espiro heterociclicos y su preparacion.
US4876260A (en) * 1987-10-28 1989-10-24 State Of Israel, Israel Institute Of Biological Research Oxathiolanes
JPH01164409A (ja) * 1987-12-18 1989-06-28 Nippon Paint Co Ltd 浄化装置
GB8808433D0 (en) * 1988-04-11 1988-05-11 Merck Sharp & Dohme Therapeutic agents
GB8816299D0 (en) * 1988-07-08 1988-08-10 Merck Sharp & Dohme Therapeutic agents
US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
US5852029A (en) * 1990-04-10 1998-12-22 Israel Institute For Biological Research Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity
EP0984970B1 (en) 1997-05-30 2003-11-19 Neurosearch A/S Spiro-quinuclidine derivatives, their preparation and use
JP4564135B2 (ja) * 1999-07-26 2010-10-20 住友化学株式会社 高純度フェノチアジン化合物とその製造方法、およびその中間体の製造方法、並びにその中間体の原料の水和物と新規結晶
WO2008073067A1 (en) * 2006-08-02 2008-06-19 Janssen Pharmaceutica N.V. Novel spiro-quinuclidinyl derivatives for the treatment of the central nervous system disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681363A (en) * 1970-08-20 1972-08-01 Univ Temple Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones

Also Published As

Publication number Publication date
AU1955476A (en) 1978-05-18
FI60015C (fi) 1981-11-10
IL48452A (en) 1979-07-25
NO145618C (no) 1982-04-28
GB1542494A (en) 1979-03-21
US4104397A (en) 1978-08-01
DE2650845A1 (de) 1977-05-18
AT356652B (de) 1980-05-12
AR214652A1 (es) 1979-07-13
FI60015B (fi) 1981-07-31
NO763819L (ja) 1977-05-12
NZ182555A (en) 1979-01-11
ATA839376A (de) 1979-10-15
AU507660B2 (en) 1980-02-21
IL48452A0 (en) 1976-01-30
CH626085A5 (ja) 1981-10-30
DK507276A (da) 1977-05-12
NO145618B (no) 1982-01-18
NL7612426A (nl) 1977-05-13
JPS5277092A (en) 1977-06-29
ZA766662B (en) 1977-10-26
FI763151A (ja) 1977-05-12
MX4395E (es) 1982-04-23
ES453161A1 (es) 1977-11-01
BE848228A (fr) 1977-03-01
JPS6259113B2 (ja) 1987-12-09
CA1071629A (en) 1980-02-12
FR2331343B1 (ja) 1980-04-04
AR213102A1 (es) 1978-12-15
DK148744B (da) 1985-09-16
ES460286A1 (es) 1978-04-01
FR2331343A1 (fr) 1977-06-10

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