DK507276A - Spiro-(1,3-dioxolan-4,3')quinuclidinforbindelser og fremgangsmade til fremstilling af disse - Google Patents

Spiro-(1,3-dioxolan-4,3')quinuclidinforbindelser og fremgangsmade til fremstilling af disse

Info

Publication number
DK507276A
DK507276A DK507276A DK507276A DK507276A DK 507276 A DK507276 A DK 507276A DK 507276 A DK507276 A DK 507276A DK 507276 A DK507276 A DK 507276A DK 507276 A DK507276 A DK 507276A
Authority
DK
Denmark
Prior art keywords
quinuclidin
dioxolane
spiro
compounds
preparation
Prior art date
Application number
DK507276A
Other languages
English (en)
Other versions
DK148744C (da
DK148744B (da
Inventor
S Cohen
A Fisher
Original Assignee
Mundipharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mundipharma Ag filed Critical Mundipharma Ag
Publication of DK507276A publication Critical patent/DK507276A/da
Priority to DK281985A priority Critical patent/DK281985D0/da
Publication of DK148744B publication Critical patent/DK148744B/da
Application granted granted Critical
Publication of DK148744C publication Critical patent/DK148744C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK507276A 1975-11-11 1976-11-10 Analogifremgangsmaade til fremstilling af den enkelte isomere eller en isomerblanding af spiro-(1,3-dioxolan-4,3') quinuclidiner eller farmaceutisk acceptable syreadditionssalte deraf DK148744C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK281985A DK281985D0 (da) 1975-11-11 1985-06-21 Analogifremgangsmaade til fremstilling af 2,2-diphenyl-spiro-(1,3-dioxolan-4,3')quinuclidin eller farmaceutisk acceptable syreadditionssalte deraf

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL4845275 1975-11-11
IL48452A IL48452A (en) 1975-11-11 1975-11-11 Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them

Publications (3)

Publication Number Publication Date
DK507276A true DK507276A (da) 1977-05-12
DK148744B DK148744B (da) 1985-09-16
DK148744C DK148744C (da) 1986-02-03

Family

ID=11048545

Family Applications (1)

Application Number Title Priority Date Filing Date
DK507276A DK148744C (da) 1975-11-11 1976-11-10 Analogifremgangsmaade til fremstilling af den enkelte isomere eller en isomerblanding af spiro-(1,3-dioxolan-4,3') quinuclidiner eller farmaceutisk acceptable syreadditionssalte deraf

Country Status (20)

Country Link
US (1) US4104397A (da)
JP (1) JPS5277092A (da)
AR (2) AR213102A1 (da)
AT (1) AT356652B (da)
AU (1) AU507660B2 (da)
BE (1) BE848228A (da)
CA (1) CA1071629A (da)
CH (1) CH626085A5 (da)
DE (1) DE2650845A1 (da)
DK (1) DK148744C (da)
ES (2) ES453161A1 (da)
FI (1) FI60015C (da)
FR (1) FR2331343A1 (da)
GB (1) GB1542494A (da)
IL (1) IL48452A (da)
MX (1) MX4395E (da)
NL (1) NL7612426A (da)
NO (1) NO145618C (da)
NZ (1) NZ182555A (da)
ZA (1) ZA766662B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2454056A1 (fr) * 1979-03-15 1980-11-07 Geissmann Robert Cheminee cinetique pouvant etre utilisee comme rotissoire
EP0189370A3 (de) * 1985-01-16 1988-01-27 Sandoz Ag Spiro-dioxolane, -dithiolane und -oxothiolane
JPS61167130A (ja) * 1985-01-17 1986-07-28 Nissan Motor Co Ltd 内燃機関の吸気装置
US4855290A (en) * 1985-05-10 1989-08-08 State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research Derivatives of quinuclidine
EP0311313B1 (en) * 1987-10-05 1995-05-10 Yamanouchi Pharmaceutical Co. Ltd. Heterocyclic spiro compounds and their preparation
US4876260A (en) * 1987-10-28 1989-10-24 State Of Israel, Israel Institute Of Biological Research Oxathiolanes
JPH01164409A (ja) * 1987-12-18 1989-06-28 Nippon Paint Co Ltd 浄化装置
GB8808433D0 (en) * 1988-04-11 1988-05-11 Merck Sharp & Dohme Therapeutic agents
GB8816299D0 (en) * 1988-07-08 1988-08-10 Merck Sharp & Dohme Therapeutic agents
US5852029A (en) * 1990-04-10 1998-12-22 Israel Institute For Biological Research Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity
US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
NZ500643A (en) 1997-05-30 2001-12-21 Neurosearch As Spiro-quinuclidine derivatives and their use in treating conditions responsive to nicotinic ACh receptor modulators
JP4564135B2 (ja) * 1999-07-26 2010-10-20 住友化学株式会社 高純度フェノチアジン化合物とその製造方法、およびその中間体の製造方法、並びにその中間体の原料の水和物と新規結晶
WO2008073067A1 (en) * 2006-08-02 2008-06-19 Janssen Pharmaceutica N.V. Novel spiro-quinuclidinyl derivatives for the treatment of the central nervous system disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681363A (en) * 1970-08-20 1972-08-01 Univ Temple Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones

Also Published As

Publication number Publication date
AU1955476A (en) 1978-05-18
GB1542494A (en) 1979-03-21
AT356652B (de) 1980-05-12
AR213102A1 (es) 1978-12-15
DK148744C (da) 1986-02-03
AU507660B2 (en) 1980-02-21
JPS6259113B2 (da) 1987-12-09
JPS5277092A (en) 1977-06-29
CH626085A5 (da) 1981-10-30
CA1071629A (en) 1980-02-12
ES460286A1 (es) 1978-04-01
NO145618B (no) 1982-01-18
NL7612426A (nl) 1977-05-13
ES453161A1 (es) 1977-11-01
IL48452A0 (en) 1976-01-30
BE848228A (fr) 1977-03-01
DK148744B (da) 1985-09-16
AR214652A1 (es) 1979-07-13
FR2331343B1 (da) 1980-04-04
NO145618C (no) 1982-04-28
MX4395E (es) 1982-04-23
FI60015B (fi) 1981-07-31
FI60015C (fi) 1981-11-10
IL48452A (en) 1979-07-25
NO763819L (da) 1977-05-12
ATA839376A (de) 1979-10-15
US4104397A (en) 1978-08-01
FR2331343A1 (fr) 1977-06-10
ZA766662B (en) 1977-10-26
DE2650845A1 (de) 1977-05-18
NZ182555A (en) 1979-01-11
FI763151A (da) 1977-05-12

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