DK1482973T3 - Fremgangsmåde til modulering af CD200-receptorer - Google Patents
Fremgangsmåde til modulering af CD200-receptorerInfo
- Publication number
- DK1482973T3 DK1482973T3 DK03716515T DK03716515T DK1482973T3 DK 1482973 T3 DK1482973 T3 DK 1482973T3 DK 03716515 T DK03716515 T DK 03716515T DK 03716515 T DK03716515 T DK 03716515T DK 1482973 T3 DK1482973 T3 DK 1482973T3
- Authority
- DK
- Denmark
- Prior art keywords
- modulating
- receptors
- methods
- agonists
- antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Virology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36451302P | 2002-03-15 | 2002-03-15 | |
| PCT/US2003/007647 WO2003077947A1 (en) | 2002-03-15 | 2003-03-13 | Methods of modulating cd200 receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1482973T3 true DK1482973T3 (da) | 2009-12-07 |
Family
ID=28041929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03716515T DK1482973T3 (da) | 2002-03-15 | 2003-03-13 | Fremgangsmåde til modulering af CD200-receptorer |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US20030223991A1 (enExample) |
| EP (3) | EP1482973B1 (enExample) |
| JP (4) | JP2005529587A (enExample) |
| AT (1) | ATE439861T1 (enExample) |
| AU (3) | AU2003220219A1 (enExample) |
| CA (1) | CA2478803A1 (enExample) |
| CY (1) | CY1109521T1 (enExample) |
| DE (1) | DE60328870D1 (enExample) |
| DK (1) | DK1482973T3 (enExample) |
| ES (1) | ES2330211T3 (enExample) |
| MX (1) | MXPA04008937A (enExample) |
| NZ (2) | NZ570998A (enExample) |
| PT (1) | PT1482973E (enExample) |
| SI (1) | SI1482973T1 (enExample) |
| WO (1) | WO2003077947A1 (enExample) |
| ZA (2) | ZA200407384B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2336321A1 (en) * | 1999-05-13 | 2011-06-22 | Medical Research Council | Ox2 receptor homolog |
| JP4381140B2 (ja) * | 2001-10-12 | 2009-12-09 | シェーリング コーポレイション | 免疫応答を調節するための二重特異性抗体の使用 |
| US20030223991A1 (en) * | 2002-03-15 | 2003-12-04 | Cherwinski Holly M. | Methods of modulating CD200 receptors |
| US20050287603A1 (en) * | 2002-06-07 | 2005-12-29 | Gorczynski Reginald M | Modulation of bone development |
| WO2004060295A2 (en) * | 2002-12-27 | 2004-07-22 | Schering Corporation | Methods of inducing and maintaining immune tolerance |
| JP2007518827A (ja) * | 2004-02-02 | 2007-07-12 | シェーリング コーポレイション | Cd200およびcd200rを調節する方法 |
| JP4919453B2 (ja) * | 2005-04-07 | 2012-04-18 | 独立行政法人理化学研究所 | 炎症性疾患の予防又は治療剤 |
| HUE030850T2 (en) | 2006-06-16 | 2017-06-28 | Univ Pennsylvania | Prostaglandin D2 receptor antagonists for the treatment of hair loss |
| BRPI0720841A2 (pt) | 2006-12-22 | 2014-03-04 | Schering Corp | Anticorpos para cd200r |
| WO2008089022A2 (en) * | 2007-01-11 | 2008-07-24 | Boehringer Ingelheim International Gmbh | Cd200 and its receptor, cd200r, modulate bone mass via the differentiation of osteoclasts |
| WO2009004339A2 (en) * | 2007-07-03 | 2009-01-08 | Imperial Innovations Limited | Compositions and methods relating to manipulation of the myeloid immune compartment during respiratory infection |
| US20120128673A1 (en) | 2009-05-20 | 2012-05-24 | Schering Corporation | Modulation of pilr receptors to treat microbial infections |
| EP2432805A1 (en) * | 2009-05-20 | 2012-03-28 | Schering Corporation | Modulation of pilr receptors to treat sepsis |
| WO2011084357A1 (en) | 2009-12-17 | 2011-07-14 | Schering Corporation | Modulation of pilr to treat immune disorders |
| US10745467B2 (en) | 2010-03-26 | 2020-08-18 | The Trustees Of Dartmouth College | VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders |
| US20150231215A1 (en) | 2012-06-22 | 2015-08-20 | Randolph J. Noelle | VISTA Antagonist and Methods of Use |
| CN103119054B (zh) | 2010-03-26 | 2017-01-18 | 达特茅斯大学理事会 | Vista调节性t细胞介体蛋白、vista结合剂及其用途 |
| US9890215B2 (en) | 2012-06-22 | 2018-02-13 | King's College London | Vista modulators for diagnosis and treatment of cancer |
| CN104619722B (zh) * | 2012-06-22 | 2022-10-04 | 达特茅斯大学理事会 | 新型vista-ig构建体和vista-ig用于治疗自身免疫性、过敏性和炎性疾病的用途 |
| CA2884704C (en) | 2012-09-07 | 2023-04-04 | Randolph J. Noelle | Vista modulators for diagnosis and treatment of cancer |
| JP5854432B2 (ja) * | 2012-09-28 | 2016-02-09 | 森永乳業株式会社 | アレルギー反応検出法 |
| US11014987B2 (en) | 2013-12-24 | 2021-05-25 | Janssen Pharmaceutics Nv | Anti-vista antibodies and fragments, uses thereof, and methods of identifying same |
| US10273301B2 (en) | 2013-12-24 | 2019-04-30 | Janssen Pharmaceutica Nv | Anti-vista antibodies and fragments |
| JP6997619B2 (ja) | 2014-06-11 | 2022-01-17 | キャシー・エイ・グリーン | 液性免疫の抑制または増進のための、vistaアゴニスト及びvistaアンタゴニストの使用 |
| MX2017007136A (es) | 2014-12-05 | 2017-12-04 | Immunext Inc | Identificacion de vsig8 como el receptor vista putativo y su uso para producir moduladores vista/vsig8. |
| EP3722314A1 (en) | 2015-06-24 | 2020-10-14 | Janssen Pharmaceutica NV | Anti-vista antibodies and fragments |
| US10899836B2 (en) | 2016-02-12 | 2021-01-26 | Janssen Pharmaceutica Nv | Method of identifying anti-VISTA antibodies |
| PE20190115A1 (es) | 2016-04-15 | 2019-01-16 | Immunext Inc | Anticuerpos vista antihumanos y su uso |
| TWI749367B (zh) * | 2018-09-14 | 2021-12-11 | 美商美國禮來大藥廠 | Cd200r促效劑抗體及其用途 |
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| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5202267A (en) | 1988-04-04 | 1993-04-13 | Hygeia Sciences, Inc. | Sol capture immunoassay kit and procedure |
| US5468468A (en) | 1989-02-09 | 1995-11-21 | The United States Of America, As Represented By The Secretary Of The Department Of Health & Human Services | Method for making a monoclonal antibody, monoclonal antibodies to α PD |
| US6176962B1 (en) | 1990-02-28 | 2001-01-23 | Aclara Biosciences, Inc. | Methods for fabricating enclosed microchannel structures |
| EP0469477B1 (en) * | 1990-08-02 | 1995-09-20 | F. Hoffmann-La Roche Ag | Antiallergic combination |
| US5856457A (en) | 1991-03-29 | 1999-01-05 | Genentech, Inc. | Nucleic acids encoding a human IL-8 receptor |
| US5440021A (en) | 1991-03-29 | 1995-08-08 | Chuntharapai; Anan | Antibodies to human IL-8 type B receptor |
| US5932448A (en) | 1991-11-29 | 1999-08-03 | Protein Design Labs., Inc. | Bispecific antibody heterodimers |
| US6129914A (en) | 1992-03-27 | 2000-10-10 | Protein Design Labs, Inc. | Bispecific antibody effective to treat B-cell lymphoma and cell line |
| US5532210A (en) | 1994-06-08 | 1996-07-02 | E. I. Du Pont De Nemours And Company | High temperature superconductor dielectric slow wave structures for accelerators and traveling wave tubes |
| US6132764A (en) | 1994-08-05 | 2000-10-17 | Targesome, Inc. | Targeted polymerized liposome diagnostic and treatment agents |
| US5919816A (en) | 1994-11-14 | 1999-07-06 | Bionumerik Pharmaceuticals, Inc. | Formulations and methods of reducing toxicity of antineoplastic agents |
| US5888530A (en) | 1995-07-21 | 1999-03-30 | The General Hospital Corporation | Method of enhancing delivery of a pharmaceutical formulation |
| US6096728A (en) | 1996-02-09 | 2000-08-01 | Amgen Inc. | Composition and method for treating inflammatory diseases |
| AU725682B2 (en) | 1996-05-27 | 2000-10-19 | Medical & Biological Laboratories Co., Ltd. | Anti-human lect2 antibody, cells producing the same, and method and kit for assaying the same |
| US6056973A (en) | 1996-10-11 | 2000-05-02 | Sequus Pharmaceuticals, Inc. | Therapeutic liposome composition and method of preparation |
| JPH10212242A (ja) * | 1996-11-27 | 1998-08-11 | Tosoh Corp | 新規血小板増多剤 |
| US6294170B1 (en) | 1997-08-08 | 2001-09-25 | Amgen Inc. | Composition and method for treating inflammatory diseases |
| US5948627A (en) | 1997-05-30 | 1999-09-07 | One Lambda | Immunobead flow cytometric detection of anti-HLA panel-reactive antibody |
| US6342220B1 (en) | 1997-08-25 | 2002-01-29 | Genentech, Inc. | Agonist antibodies |
| US6989435B2 (en) * | 1997-09-11 | 2006-01-24 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| US5842787A (en) | 1997-10-09 | 1998-12-01 | Caliper Technologies Corporation | Microfluidic systems incorporating varied channel dimensions |
| JPH11246435A (ja) * | 1997-10-29 | 1999-09-14 | Ajinomoto Co Inc | 免疫調整剤 |
| US6312689B1 (en) | 1998-07-23 | 2001-11-06 | Millennium Pharmaceuticals, Inc. | Anti-CCR2 antibodies and methods of use therefor |
| EP1100869A4 (en) * | 1998-07-30 | 2005-04-27 | Human Genome Sciences Inc | 98 HUMAN SECRETED PROTEINS |
| WO2000032634A1 (en) | 1998-12-01 | 2000-06-08 | Protein Design Labs, Inc. | Humanized antibodies to gamma-interferon |
| EP2336321A1 (en) * | 1999-05-13 | 2011-06-22 | Medical Research Council | Ox2 receptor homolog |
| CA2417874C (en) * | 2000-08-03 | 2012-10-02 | Transplantation Technologies Inc. | Use of ox-2 inhibitors for the treatment of cancer |
| US7186818B2 (en) * | 2001-04-26 | 2007-03-06 | Immunex Corporation | DNA encoding soluble variants of human OX2 receptors |
| WO2002095030A2 (en) * | 2001-05-24 | 2002-11-28 | Trillium Therapeutics Inc. | Modulation of cd200 receptors |
| JP4381140B2 (ja) * | 2001-10-12 | 2009-12-09 | シェーリング コーポレイション | 免疫応答を調節するための二重特異性抗体の使用 |
| US20040126777A1 (en) * | 2002-01-28 | 2004-07-01 | Bhatt Ramesh Rajani | Lp mammalian proteins; related reagents |
| US20030223991A1 (en) * | 2002-03-15 | 2003-12-04 | Cherwinski Holly M. | Methods of modulating CD200 receptors |
-
2003
- 2003-03-13 US US10/389,231 patent/US20030223991A1/en not_active Abandoned
- 2003-03-13 WO PCT/US2003/007647 patent/WO2003077947A1/en not_active Ceased
- 2003-03-13 NZ NZ570998A patent/NZ570998A/en not_active IP Right Cessation
- 2003-03-13 ES ES03716515T patent/ES2330211T3/es not_active Expired - Lifetime
- 2003-03-13 EP EP03716515A patent/EP1482973B1/en not_active Expired - Lifetime
- 2003-03-13 AT AT03716515T patent/ATE439861T1/de active
- 2003-03-13 CA CA002478803A patent/CA2478803A1/en not_active Abandoned
- 2003-03-13 AU AU2003220219A patent/AU2003220219A1/en not_active Abandoned
- 2003-03-13 NZ NZ553470A patent/NZ553470A/en not_active IP Right Cessation
- 2003-03-13 PT PT03716515T patent/PT1482973E/pt unknown
- 2003-03-13 DE DE60328870T patent/DE60328870D1/de not_active Expired - Lifetime
- 2003-03-13 MX MXPA04008937A patent/MXPA04008937A/es active IP Right Grant
- 2003-03-13 JP JP2003576000A patent/JP2005529587A/ja active Pending
- 2003-03-13 SI SI200331692T patent/SI1482973T1/sl unknown
- 2003-03-13 EP EP09163830A patent/EP2100617A1/en not_active Withdrawn
- 2003-03-13 EP EP10183878A patent/EP2322218A1/en not_active Withdrawn
- 2003-03-13 DK DK03716515T patent/DK1482973T3/da active
-
2004
- 2004-09-14 ZA ZA200407384A patent/ZA200407384B/xx unknown
-
2006
- 2006-03-03 JP JP2006058745A patent/JP2006206598A/ja active Pending
- 2006-06-29 US US11/478,778 patent/US20060240010A1/en not_active Abandoned
-
2007
- 2007-06-26 AU AU2007202938A patent/AU2007202938B2/en not_active Ceased
-
2008
- 2008-03-10 US US12/045,153 patent/US8263070B2/en not_active Expired - Fee Related
-
2009
- 2009-10-26 CY CY20091101112T patent/CY1109521T1/el unknown
-
2010
- 2010-03-04 ZA ZA2010/01595A patent/ZA201001595B/en unknown
-
2011
- 2011-04-20 AU AU2011201824A patent/AU2011201824A1/en not_active Abandoned
- 2011-06-16 JP JP2011134635A patent/JP2011178813A/ja not_active Withdrawn
- 2011-06-16 JP JP2011134634A patent/JP2011178812A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CY1109521T1 (el) | 2014-08-13 |
| NZ570998A (en) | 2010-08-27 |
| AU2003220219A1 (en) | 2003-09-29 |
| NZ553470A (en) | 2008-10-31 |
| EP1482973B1 (en) | 2009-08-19 |
| EP1482973A4 (en) | 2006-03-08 |
| US20030223991A1 (en) | 2003-12-04 |
| DE60328870D1 (de) | 2009-10-01 |
| JP2005529587A (ja) | 2005-10-06 |
| ZA200407384B (en) | 2010-05-26 |
| ATE439861T1 (de) | 2009-09-15 |
| EP2322218A1 (en) | 2011-05-18 |
| ES2330211T3 (es) | 2009-12-07 |
| ZA201001595B (en) | 2012-11-28 |
| US20060240010A1 (en) | 2006-10-26 |
| SI1482973T1 (sl) | 2010-01-29 |
| EP2100617A1 (en) | 2009-09-16 |
| US8263070B2 (en) | 2012-09-11 |
| MXPA04008937A (es) | 2005-06-17 |
| EP1482973A1 (en) | 2004-12-08 |
| JP2011178812A (ja) | 2011-09-15 |
| JP2011178813A (ja) | 2011-09-15 |
| JP2006206598A (ja) | 2006-08-10 |
| WO2003077947A1 (en) | 2003-09-25 |
| AU2007202938B2 (en) | 2011-01-20 |
| PT1482973E (pt) | 2009-11-20 |
| AU2011201824A1 (en) | 2011-05-19 |
| CA2478803A1 (en) | 2003-09-25 |
| AU2007202938A1 (en) | 2007-07-19 |
| US20080166353A1 (en) | 2008-07-10 |
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