DK1480970T3 - Quinolinderivater - Google Patents

Quinolinderivater

Info

Publication number
DK1480970T3
DK1480970T3 DK03714784T DK03714784T DK1480970T3 DK 1480970 T3 DK1480970 T3 DK 1480970T3 DK 03714784 T DK03714784 T DK 03714784T DK 03714784 T DK03714784 T DK 03714784T DK 1480970 T3 DK1480970 T3 DK 1480970T3
Authority
DK
Denmark
Prior art keywords
quinoline
Prior art date
Application number
DK03714784T
Other languages
Danish (da)
English (en)
Inventor
Peter Gull
Villar Esteban Pombo
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK1480970T3 publication Critical patent/DK1480970T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK03714784T 2002-03-07 2003-03-06 Quinolinderivater DK1480970T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02005117 2002-03-07
EP02005115 2002-03-07
PCT/EP2003/002321 WO2003074511A1 (fr) 2002-03-07 2003-03-06 Derives de quinoline

Publications (1)

Publication Number Publication Date
DK1480970T3 true DK1480970T3 (da) 2007-03-05

Family

ID=27790094

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03714784T DK1480970T3 (da) 2002-03-07 2003-03-06 Quinolinderivater

Country Status (29)

Country Link
US (2) US7399768B2 (fr)
EP (1) EP1480970B1 (fr)
JP (2) JP2005519117A (fr)
KR (1) KR101027977B1 (fr)
CN (2) CN1939915A (fr)
AR (1) AR038730A1 (fr)
AU (1) AU2003219023B2 (fr)
BR (1) BR0308201A (fr)
CA (2) CA2477720C (fr)
CO (1) CO5611196A2 (fr)
CY (1) CY1106409T1 (fr)
DE (1) DE60311233T2 (fr)
DK (1) DK1480970T3 (fr)
EC (1) ECSP045271A (fr)
EG (1) EG24415A (fr)
ES (1) ES2279100T3 (fr)
HK (1) HK1071364A1 (fr)
IL (1) IL163769A0 (fr)
MX (1) MXPA04008666A (fr)
MY (1) MY134325A (fr)
NO (1) NO20044117L (fr)
NZ (1) NZ534732A (fr)
PE (1) PE20030927A1 (fr)
PL (2) PL215012B1 (fr)
PT (1) PT1480970E (fr)
RU (1) RU2345991C2 (fr)
SI (1) SI1480970T1 (fr)
TW (1) TW200406401A (fr)
WO (1) WO2003074511A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1757601B1 (fr) * 2002-03-07 2009-08-05 Novartis AG Dérivés de quinoline et leur utilisation en glaucome et myopie
US10729710B2 (en) 2017-11-24 2020-08-04 H. Lundbeck A/S Catecholamine prodrugs for use in the treatment of Parkinson's disease
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100555A (en) * 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
GB9326010D0 (en) * 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
TW378209B (en) * 1996-07-08 2000-01-01 Novartis Ag Benzo[g]quinoline derivatives, their preparation and the pharmaceutical composition containing them
PE20030240A1 (es) * 2001-07-09 2003-04-16 Novartis Ag DERIVADOS DE BENZO [g] QUINOLINA

Also Published As

Publication number Publication date
HK1071364A1 (en) 2005-07-15
EP1480970B1 (fr) 2007-01-17
ES2279100T3 (es) 2007-08-16
IL163769A0 (en) 2005-12-18
ECSP045271A (es) 2004-10-26
CN1639148A (zh) 2005-07-13
AU2003219023A1 (en) 2003-09-16
PT1480970E (pt) 2007-03-30
KR101027977B1 (ko) 2011-04-13
CN1939915A (zh) 2007-04-04
PL370915A1 (en) 2005-06-13
MXPA04008666A (es) 2004-12-06
US20080255176A1 (en) 2008-10-16
SI1480970T1 (sl) 2007-06-30
US7399768B2 (en) 2008-07-15
TW200406401A (en) 2004-05-01
AU2003219023B2 (en) 2006-11-30
PL210336B1 (pl) 2012-01-31
PL394208A1 (pl) 2011-08-16
BR0308201A (pt) 2005-01-04
DE60311233T2 (de) 2007-11-15
CA2477720A1 (fr) 2003-09-12
RU2345991C2 (ru) 2009-02-10
RU2004129767A (ru) 2005-06-27
US20050234085A1 (en) 2005-10-20
EP1480970A1 (fr) 2004-12-01
JP2010095550A (ja) 2010-04-30
WO2003074511A1 (fr) 2003-09-12
CA2706618A1 (fr) 2003-09-12
PE20030927A1 (es) 2003-12-26
CA2477720C (fr) 2010-09-21
JP2005519117A (ja) 2005-06-30
DE60311233D1 (de) 2007-03-08
EG24415A (en) 2009-05-25
PL215012B1 (pl) 2013-10-31
NO20044117L (no) 2004-09-28
KR20040089615A (ko) 2004-10-21
CO5611196A2 (es) 2006-02-28
CN1293070C (zh) 2007-01-03
CY1106409T1 (el) 2011-10-12
AR038730A1 (es) 2005-01-26
NZ534732A (en) 2006-05-26
MY134325A (en) 2007-12-31

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