DK1467983T3 - Fremgangsmåde til fremstilling af ren thioctsyre - Google Patents

Fremgangsmåde til fremstilling af ren thioctsyre

Info

Publication number
DK1467983T3
DK1467983T3 DK03729427T DK03729427T DK1467983T3 DK 1467983 T3 DK1467983 T3 DK 1467983T3 DK 03729427 T DK03729427 T DK 03729427T DK 03729427 T DK03729427 T DK 03729427T DK 1467983 T3 DK1467983 T3 DK 1467983T3
Authority
DK
Denmark
Prior art keywords
preparation
thioctic acid
pure
pure thioctic
acid
Prior art date
Application number
DK03729427T
Other languages
Danish (da)
English (en)
Inventor
Peter Meisel
Gilbert Mueller
Gunter Laban
Original Assignee
Viatris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viatris Gmbh filed Critical Viatris Gmbh
Application granted granted Critical
Publication of DK1467983T3 publication Critical patent/DK1467983T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treating Waste Gases (AREA)
DK03729427T 2002-01-16 2003-01-07 Fremgangsmåde til fremstilling af ren thioctsyre DK1467983T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10201464A DE10201464B4 (de) 2002-01-16 2002-01-16 Verfahren zur Herstellung reiner Thioctsäure

Publications (1)

Publication Number Publication Date
DK1467983T3 true DK1467983T3 (da) 2006-08-07

Family

ID=7712279

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03729427T DK1467983T3 (da) 2002-01-16 2003-01-07 Fremgangsmåde til fremstilling af ren thioctsyre

Country Status (11)

Country Link
US (1) US7208609B2 (es)
EP (1) EP1467983B1 (es)
JP (1) JP2005515228A (es)
AT (1) ATE322489T1 (es)
AU (1) AU2003210152A1 (es)
CY (1) CY1105255T1 (es)
DE (2) DE10201464B4 (es)
DK (1) DK1467983T3 (es)
ES (1) ES2260625T3 (es)
PT (1) PT1467983E (es)
WO (1) WO2003059902A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20050466A1 (it) * 2005-03-22 2006-09-23 Laboratorio Chimico Int Spa Processo di purificazione in acqua di acido tiottico
US20090078581A1 (en) * 2007-09-24 2009-03-26 Applied Intellectual Capital Configurations and Methods of Reduction of Lipoic Acid
KR20110103987A (ko) * 2008-12-01 2011-09-21 인베이스크 테라퓨틱, 인크. 레닌-안지오텐신 알도스테론계 억제제 및 리포산 화합물을 포함하는 조성물, 및 레닌-안지오텐신 알도스테론계 관련 질환의 치료를 위한 이의 용도
JP2013155145A (ja) * 2012-01-31 2013-08-15 Sumitomo Seika Chem Co Ltd 環状ジスルフィド化合物の製造方法
CN105524040A (zh) * 2016-02-19 2016-04-27 苏州富士莱医药股份有限公司 一种r-硫辛酸的制备方法
CN105622571A (zh) * 2016-03-08 2016-06-01 苏州富士莱医药股份有限公司 一种r-硫辛酸氨基丁三醇盐的制备方法
CN112480065A (zh) * 2020-12-15 2021-03-12 苏州富士莱医药股份有限公司 一种硫辛酸杂质的制备方法
CN113292533B (zh) * 2021-05-25 2024-04-16 四川智强医药科技开发有限公司 硫辛酸中聚合物杂质的纯化方法
CN114149324B (zh) * 2021-12-07 2023-08-22 厦门金达威维生素有限公司 一种6-羟基-8-氯辛酸乙酯、6,8-二氯辛酸乙酯及硫辛酸的合成方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797298A (en) * 1980-01-21 1989-01-10 Pfizer, Inc. Branched amides of L-aspartyl-D-amino acid dipeptides
DE19533881A1 (de) * 1995-09-13 1997-03-20 Dresden Arzneimittel Herstellung und Verwendung der reinen Enantiomere der 8-Chlor-6-sulfonyloxy-octansäuren und ihrer Alkylester und der reinen Enantiomere der 6,8-Dichlor-octansäure und ihrer Alkylester
DE19601787C1 (de) 1996-01-19 1997-07-24 Asta Medica Ag Herstellung und Verwendung von Salzen der 6,8-Bis(amidiniumthio)-octansäure
DE19709069C2 (de) 1997-03-06 2000-04-06 Asta Medica Ag Enantiomerenreine 3-Hydroxyoctandisäurediester, Verfahren zur Herstellung derselben durch asymmetrische katalytische Hydrierung sowie Verfahren zur Herstellung von R-(+)- und S-(-)-alpha-Liponsäure
AU728488B2 (en) * 1997-04-02 2001-01-11 Sankyo Company Limited Dithiolan derivatives, their preparation and their therapeutic effect
DE19834608A1 (de) * 1998-07-31 2000-02-03 Basf Ag Kristallmodifikation der Liponsäure
US6288106B1 (en) * 1999-05-25 2001-09-11 Chronorx, Llc Processes for the synthesis and use of various α-lipoic acid complexes
DE19938621A1 (de) * 1999-08-14 2001-02-22 Sueddeutsche Kalkstickstoff Verfahren zur Herstellung von lösemittelfreier alpha-Liponsäure
IT1319196B1 (it) * 2000-10-10 2003-09-26 Laboratorio Chimico Int Spa Sintesi dell'acido r(+)alfa-lipoico.
IT1319194B1 (it) * 2000-10-10 2003-09-26 Laboratorio Chimico Int Spa Processo per la produzione dell'acido tiottico racemo.
JP2004514716A (ja) * 2000-11-30 2004-05-20 ビーエーエスエフ　アクチェンゲゼルシャフト リポ酸およびジヒドロリポ酸の調製方法
DE10137381A1 (de) * 2001-07-31 2003-02-13 Viatris Gmbh Neue Modifikationen des Trometamolsalzes der R-Thioctsäure sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
AU2003210152A1 (en) 2003-07-30
DE10201464A1 (de) 2003-07-31
WO2003059902A1 (de) 2003-07-24
DE50302888D1 (de) 2006-05-18
ES2260625T3 (es) 2006-11-01
EP1467983A1 (de) 2004-10-20
PT1467983E (pt) 2006-08-31
DE10201464B4 (de) 2005-06-16
US20050107620A1 (en) 2005-05-19
CY1105255T1 (el) 2010-03-03
JP2005515228A (ja) 2005-05-26
EP1467983B1 (de) 2006-04-05
ATE322489T1 (de) 2006-04-15
US7208609B2 (en) 2007-04-24

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