DK146787A - Heterocykliske forbindelser, deres fremstilling og anvendelse - Google Patents
Heterocykliske forbindelser, deres fremstilling og anvendelseInfo
- Publication number
- DK146787A DK146787A DK146787A DK146787A DK146787A DK 146787 A DK146787 A DK 146787A DK 146787 A DK146787 A DK 146787A DK 146787 A DK146787 A DK 146787A DK 146787 A DK146787 A DK 146787A
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- preparation
- heterocyclic compounds
- chem
- so2nh2
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyrrole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK146787A DK146787A (da) | 1987-03-23 | 1987-03-23 | Heterocykliske forbindelser, deres fremstilling og anvendelse |
IL85328A IL85328A (en) | 1987-03-23 | 1988-02-05 | Pharmaceutical compositions containing 2,3-dihydroxy- (phenyl, pyridyl or cyclohexenanyl)- quinoxaline derivatives, their preparation and certain novel such quinoxalines |
US07/156,539 US4889855A (en) | 1987-03-23 | 1988-02-16 | Heterocyclic compounds and their preparation and use |
ZA881139A ZA881139B (en) | 1987-03-23 | 1988-02-18 | Heterocyclic compounds and their preparation and use |
IE43988A IE60002B1 (en) | 1987-03-23 | 1988-02-18 | Heterocyclic compounds and their preparation and use |
FI880816A FI92582C (fi) | 1987-03-23 | 1988-02-22 | Menetelmä uusien terapeuttisesti käyttökelpoisten kinoksaliinijohdannaisten valmistamiseksi |
PH36561A PH23979A (en) | 1987-03-23 | 1988-02-26 | 2,3-dihydroxy-quinolines and pharmaceutical composition containing them |
NZ223776A NZ223776A (en) | 1987-03-23 | 1988-03-07 | Substituted quinoxaline derivatives and pharmaceutical compositions |
DK142188A DK159434C (da) | 1987-03-23 | 1988-03-16 | Quinoxalinforbindelser, fremgangsmaade til deres fremstilling, en anvendelse af forbindelserne og farmaceutiske praeparater hvori forbindelserne indgaar |
CA000561757A CA1315789C (en) | 1987-03-23 | 1988-03-17 | Quinoxaline glutamate-antagonistic compounds and pharmaceutical compositions thereof |
ES198888104379T ES2037753T3 (es) | 1987-03-23 | 1988-03-18 | Compuestos heterociclicos y su preparacion y uso. |
EP88104379A EP0283959B1 (en) | 1987-03-23 | 1988-03-18 | Heterocyclic compounds and their preparation and use |
AT88104379T ATE71090T1 (de) | 1987-03-23 | 1988-03-18 | Heterocyclische verbindungen und deren herstellung und verwendung. |
DE8888104379T DE3867268D1 (de) | 1987-03-23 | 1988-03-18 | Heterocyclische verbindungen und deren herstellung und verwendung. |
AU13260/88A AU596737B2 (en) | 1987-03-23 | 1988-03-18 | Heterocyclic dihydroquinoxaline compounds and their preparation and use |
NO881264A NO174549C (no) | 1987-03-23 | 1988-03-22 | Analogifremgangsmåte for fremstilling av terapeutisk aktive, asymmetrisk substituerte, heterocykliske forbindelser |
KR1019880003024A KR960003324B1 (ko) | 1987-03-23 | 1988-03-22 | 헤테로사이클릭 화합물, 이의 제조방법 및 이를 함유하는 약제학적 조성물 |
PT87063A PT87063B (pt) | 1987-03-23 | 1988-03-23 | Processo de preparacao de compostos heterociclicosdi-hidroxiquinoxalina e de composicoes farmaceuticas que os contem |
US07/347,141 US4912108A (en) | 1987-03-23 | 1989-05-03 | Pyridoquinoxaline compounds and their preparation and use as glutamate antagonists |
GR920400325T GR3003910T3 (ko) | 1987-03-23 | 1992-02-27 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK146787A DK146787A (da) | 1987-03-23 | 1987-03-23 | Heterocykliske forbindelser, deres fremstilling og anvendelse |
Publications (2)
Publication Number | Publication Date |
---|---|
DK146787D0 DK146787D0 (da) | 1987-03-23 |
DK146787A true DK146787A (da) | 1988-09-24 |
Family
ID=8105140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK146787A DK146787A (da) | 1987-03-23 | 1987-03-23 | Heterocykliske forbindelser, deres fremstilling og anvendelse |
Country Status (18)
Country | Link |
---|---|
US (2) | US4889855A (ko) |
EP (1) | EP0283959B1 (ko) |
KR (1) | KR960003324B1 (ko) |
AT (1) | ATE71090T1 (ko) |
AU (1) | AU596737B2 (ko) |
CA (1) | CA1315789C (ko) |
DE (1) | DE3867268D1 (ko) |
DK (1) | DK146787A (ko) |
ES (1) | ES2037753T3 (ko) |
FI (1) | FI92582C (ko) |
GR (1) | GR3003910T3 (ko) |
IE (1) | IE60002B1 (ko) |
IL (1) | IL85328A (ko) |
NO (1) | NO174549C (ko) |
NZ (1) | NZ223776A (ko) |
PH (1) | PH23979A (ko) |
PT (1) | PT87063B (ko) |
ZA (1) | ZA881139B (ko) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4743607A (en) * | 1987-05-29 | 1988-05-10 | Merrell Dow Pharmaceuticals Inc. | Cardiotonic tricyclic imidazolones |
NO179551C (no) * | 1987-11-10 | 1996-10-30 | Novo Nordisk As | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
DK160941C (da) * | 1988-06-28 | 1991-10-21 | Novo Nordisk As | Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar |
US5308845A (en) * | 1988-12-22 | 1994-05-03 | Novo Nordisk A/S | Quinoxaline compounds and their preparation and use |
DK715888D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
DK716188D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
PT99864B (pt) | 1990-12-21 | 1999-06-30 | Schering Ag | Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato |
DK73091D0 (da) * | 1991-04-22 | 1991-04-22 | Novo Nordisk As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
DE69224069T2 (de) * | 1991-09-09 | 1998-07-02 | Warner-Lambert Co., Ann Arbor, Mich. | Pharmazeutisches kombinationspräparat, das ein uricosurisches mittel und einen excitatorischen aminosäure-antagonisten enthält |
DE4217952A1 (de) * | 1992-05-30 | 1993-12-02 | Basf Ag | Chinoxalin-2,3(1H,4H)-dione |
ES2313714T3 (es) * | 1992-06-22 | 2009-03-01 | The Regents Of The University Of California | Antagonistas de receptores de glicina y uso de los mismos. |
EP0664807B1 (en) * | 1992-10-13 | 1997-09-10 | Warner-Lambert Company | Quinoxalinedione derivatives as eaa antagonists |
DK12293D0 (da) * | 1993-02-02 | 1993-02-02 | Novo Nordisk As | Heterocykliske forbindelser og deres fremstilling og anvendelse |
ATE161259T1 (de) * | 1993-05-13 | 1998-01-15 | Neurosearch As | Ampa antagonisten und behandlungsmethode |
US5843945A (en) * | 1993-05-13 | 1998-12-01 | Neurosearch A/S | AMPA antagonists and a method of treatment |
US5631373A (en) * | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
GB9419318D0 (en) * | 1994-09-24 | 1994-11-09 | Pfizer Ltd | Therapeutic agents |
DE4436852A1 (de) * | 1994-10-14 | 1996-04-18 | Basf Ag | Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung |
WO1996017832A1 (en) * | 1994-12-07 | 1996-06-13 | Warner-Lambert Company | Novel glutamate receptor antagonists: fused cycloalkylquinoxalinediones |
US5721234A (en) * | 1994-12-07 | 1998-02-24 | Warner-Lambert Company | Glutamate receptor antagonists: fused cycloalkylouinoxalinediones |
EP0809624B1 (en) * | 1995-02-15 | 2001-08-29 | Bearsden Bio, Inc. | Alkylcarboxy amino acids-modulators of the kainate receptor |
AU4423496A (en) * | 1995-03-14 | 1996-10-02 | Warner-Lambert Company | Novel glutamate (ampa/kainate) receptor antagonists: n-substituted fused azacycloalkylquinoxalinediones |
US5719153A (en) * | 1995-08-15 | 1998-02-17 | American Home Products Corporation | 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones |
WO1998005651A1 (en) * | 1996-08-01 | 1998-02-12 | Warner-Lambert Company | Novel glutamate receptor antagonists: fused cycloalkyl quinoxalinediones |
FR2752163B1 (fr) * | 1996-08-12 | 1998-10-30 | Pf Medicament | Utilisation de l'efaroxan pour la fabricaton de medicament destine au traitement de la maladie de huntington |
US5968928A (en) * | 1996-09-19 | 1999-10-19 | Warner-Lambert Company | Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof |
EP3427729A1 (en) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid for use in treating epileptic diseases, disorders or conditions |
EP4403185A1 (en) | 2021-09-15 | 2024-07-24 | University of The Ryukyus | Pharmaceutical composition for treating cognitive decline or for treating overweightness or obesity |
WO2023042887A1 (ja) | 2021-09-15 | 2023-03-23 | 国立大学法人 琉球大学 | 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3431111A (en) * | 1963-06-10 | 1969-03-04 | Eastman Kodak Co | Cyanine dyes |
US3772273A (en) * | 1969-01-17 | 1973-11-13 | Allied Chem | Derivatives of quinoxaline |
US3962440A (en) * | 1973-12-26 | 1976-06-08 | Eli Lilly And Company | Quinoxaline compounds as hypnotic agents |
US4430502A (en) * | 1982-08-13 | 1984-02-07 | The Upjohn Company | Pyridinyl substituted benzimidazoles and quinoxalines |
FR2583751B1 (fr) * | 1985-06-20 | 1989-10-13 | Panmedica | Nouveaux antibacteriens contenant des derives des acides oxo-4-pyridine carboxyliques et leur procede de preparation |
-
1987
- 1987-03-23 DK DK146787A patent/DK146787A/da not_active IP Right Cessation
-
1988
- 1988-02-05 IL IL85328A patent/IL85328A/xx not_active IP Right Cessation
- 1988-02-16 US US07/156,539 patent/US4889855A/en not_active Expired - Lifetime
- 1988-02-18 IE IE43988A patent/IE60002B1/en not_active IP Right Cessation
- 1988-02-18 ZA ZA881139A patent/ZA881139B/xx unknown
- 1988-02-22 FI FI880816A patent/FI92582C/fi not_active IP Right Cessation
- 1988-02-26 PH PH36561A patent/PH23979A/en unknown
- 1988-03-07 NZ NZ223776A patent/NZ223776A/xx unknown
- 1988-03-17 CA CA000561757A patent/CA1315789C/en not_active Expired - Fee Related
- 1988-03-18 ES ES198888104379T patent/ES2037753T3/es not_active Expired - Lifetime
- 1988-03-18 AT AT88104379T patent/ATE71090T1/de not_active IP Right Cessation
- 1988-03-18 DE DE8888104379T patent/DE3867268D1/de not_active Expired - Fee Related
- 1988-03-18 EP EP88104379A patent/EP0283959B1/en not_active Expired - Lifetime
- 1988-03-18 AU AU13260/88A patent/AU596737B2/en not_active Ceased
- 1988-03-22 KR KR1019880003024A patent/KR960003324B1/ko not_active IP Right Cessation
- 1988-03-22 NO NO881264A patent/NO174549C/no unknown
- 1988-03-23 PT PT87063A patent/PT87063B/pt active IP Right Grant
-
1989
- 1989-05-03 US US07/347,141 patent/US4912108A/en not_active Expired - Lifetime
-
1992
- 1992-02-27 GR GR920400325T patent/GR3003910T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0283959B1 (en) | 1992-01-02 |
ATE71090T1 (de) | 1992-01-15 |
US4889855A (en) | 1989-12-26 |
DK146787D0 (da) | 1987-03-23 |
AU1326088A (en) | 1988-09-22 |
US4912108A (en) | 1990-03-27 |
NO881264D0 (no) | 1988-03-22 |
IL85328A (en) | 1993-06-10 |
NO174549C (no) | 1994-05-25 |
DE3867268D1 (de) | 1992-02-13 |
NO881264L (no) | 1988-09-26 |
FI92582C (fi) | 1994-12-12 |
IE60002B1 (en) | 1994-05-18 |
AU596737B2 (en) | 1990-05-10 |
KR880011125A (ko) | 1988-10-26 |
FI880816A0 (fi) | 1988-02-22 |
CA1315789C (en) | 1993-04-06 |
PT87063B (pt) | 1992-07-31 |
NO174549B (no) | 1994-02-14 |
FI880816A (fi) | 1988-09-24 |
PT87063A (pt) | 1988-04-01 |
ES2037753T3 (es) | 1993-07-01 |
GR3003910T3 (ko) | 1993-03-16 |
KR960003324B1 (ko) | 1996-03-08 |
FI92582B (fi) | 1994-08-31 |
ZA881139B (en) | 1988-08-15 |
NZ223776A (en) | 1990-10-26 |
EP0283959A1 (en) | 1988-09-28 |
IE880439L (en) | 1988-09-23 |
PH23979A (en) | 1990-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment | ||
PBP | Patent lapsed |