DK146787A - Heterocykliske forbindelser, deres fremstilling og anvendelse - Google Patents

Heterocykliske forbindelser, deres fremstilling og anvendelse

Info

Publication number
DK146787A
DK146787A DK146787A DK146787A DK146787A DK 146787 A DK146787 A DK 146787A DK 146787 A DK146787 A DK 146787A DK 146787 A DK146787 A DK 146787A DK 146787 A DK146787 A DK 146787A
Authority
DK
Denmark
Prior art keywords
compounds
preparation
heterocyclic compounds
chem
so2nh2
Prior art date
Application number
DK146787A
Other languages
Danish (da)
English (en)
Other versions
DK146787D0 (da
Inventor
Poul Jacobsen
Flemming Elmelund Nielsen
Tage Honore
Original Assignee
Ferrosan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of DK146787D0 publication Critical patent/DK146787D0/da
Priority to DK146787A priority Critical patent/DK146787A/da
Application filed by Ferrosan filed Critical Ferrosan
Priority to IL85328A priority patent/IL85328A/xx
Priority to US07/156,539 priority patent/US4889855A/en
Priority to ZA881139A priority patent/ZA881139B/xx
Priority to IE43988A priority patent/IE60002B1/en
Priority to FI880816A priority patent/FI92582C/fi
Priority to PH36561A priority patent/PH23979A/en
Priority to NZ223776A priority patent/NZ223776A/xx
Priority to DK142188A priority patent/DK159434C/da
Priority to CA000561757A priority patent/CA1315789C/en
Priority to EP88104379A priority patent/EP0283959B1/en
Priority to AT88104379T priority patent/ATE71090T1/de
Priority to DE8888104379T priority patent/DE3867268D1/de
Priority to AU13260/88A priority patent/AU596737B2/en
Priority to ES198888104379T priority patent/ES2037753T3/es
Priority to NO881264A priority patent/NO174549C/no
Priority to KR1019880003024A priority patent/KR960003324B1/ko
Priority to PT87063A priority patent/PT87063B/pt
Publication of DK146787A publication Critical patent/DK146787A/da
Priority to US07/347,141 priority patent/US4912108A/en
Priority to GR920400325T priority patent/GR3003910T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK146787A 1987-03-23 1987-03-23 Heterocykliske forbindelser, deres fremstilling og anvendelse DK146787A (da)

Priority Applications (20)

Application Number Priority Date Filing Date Title
DK146787A DK146787A (da) 1987-03-23 1987-03-23 Heterocykliske forbindelser, deres fremstilling og anvendelse
IL85328A IL85328A (en) 1987-03-23 1988-02-05 Pharmaceutical compositions containing 2,3-dihydroxy- (phenyl, pyridyl or cyclohexenanyl)- quinoxaline derivatives, their preparation and certain novel such quinoxalines
US07/156,539 US4889855A (en) 1987-03-23 1988-02-16 Heterocyclic compounds and their preparation and use
ZA881139A ZA881139B (en) 1987-03-23 1988-02-18 Heterocyclic compounds and their preparation and use
IE43988A IE60002B1 (en) 1987-03-23 1988-02-18 Heterocyclic compounds and their preparation and use
FI880816A FI92582C (fi) 1987-03-23 1988-02-22 Menetelmä uusien terapeuttisesti käyttökelpoisten kinoksaliinijohdannaisten valmistamiseksi
PH36561A PH23979A (en) 1987-03-23 1988-02-26 2,3-dihydroxy-quinolines and pharmaceutical composition containing them
NZ223776A NZ223776A (en) 1987-03-23 1988-03-07 Substituted quinoxaline derivatives and pharmaceutical compositions
DK142188A DK159434C (da) 1987-03-23 1988-03-16 Quinoxalinforbindelser, fremgangsmaade til deres fremstilling, en anvendelse af forbindelserne og farmaceutiske praeparater hvori forbindelserne indgaar
CA000561757A CA1315789C (en) 1987-03-23 1988-03-17 Quinoxaline glutamate-antagonistic compounds and pharmaceutical compositions thereof
ES198888104379T ES2037753T3 (es) 1987-03-23 1988-03-18 Compuestos heterociclicos y su preparacion y uso.
EP88104379A EP0283959B1 (en) 1987-03-23 1988-03-18 Heterocyclic compounds and their preparation and use
AT88104379T ATE71090T1 (de) 1987-03-23 1988-03-18 Heterocyclische verbindungen und deren herstellung und verwendung.
DE8888104379T DE3867268D1 (de) 1987-03-23 1988-03-18 Heterocyclische verbindungen und deren herstellung und verwendung.
AU13260/88A AU596737B2 (en) 1987-03-23 1988-03-18 Heterocyclic dihydroquinoxaline compounds and their preparation and use
NO881264A NO174549C (no) 1987-03-23 1988-03-22 Analogifremgangsmåte for fremstilling av terapeutisk aktive, asymmetrisk substituerte, heterocykliske forbindelser
KR1019880003024A KR960003324B1 (ko) 1987-03-23 1988-03-22 헤테로사이클릭 화합물, 이의 제조방법 및 이를 함유하는 약제학적 조성물
PT87063A PT87063B (pt) 1987-03-23 1988-03-23 Processo de preparacao de compostos heterociclicosdi-hidroxiquinoxalina e de composicoes farmaceuticas que os contem
US07/347,141 US4912108A (en) 1987-03-23 1989-05-03 Pyridoquinoxaline compounds and their preparation and use as glutamate antagonists
GR920400325T GR3003910T3 (ko) 1987-03-23 1992-02-27

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK146787A DK146787A (da) 1987-03-23 1987-03-23 Heterocykliske forbindelser, deres fremstilling og anvendelse

Publications (2)

Publication Number Publication Date
DK146787D0 DK146787D0 (da) 1987-03-23
DK146787A true DK146787A (da) 1988-09-24

Family

ID=8105140

Family Applications (1)

Application Number Title Priority Date Filing Date
DK146787A DK146787A (da) 1987-03-23 1987-03-23 Heterocykliske forbindelser, deres fremstilling og anvendelse

Country Status (18)

Country Link
US (2) US4889855A (ko)
EP (1) EP0283959B1 (ko)
KR (1) KR960003324B1 (ko)
AT (1) ATE71090T1 (ko)
AU (1) AU596737B2 (ko)
CA (1) CA1315789C (ko)
DE (1) DE3867268D1 (ko)
DK (1) DK146787A (ko)
ES (1) ES2037753T3 (ko)
FI (1) FI92582C (ko)
GR (1) GR3003910T3 (ko)
IE (1) IE60002B1 (ko)
IL (1) IL85328A (ko)
NO (1) NO174549C (ko)
NZ (1) NZ223776A (ko)
PH (1) PH23979A (ko)
PT (1) PT87063B (ko)
ZA (1) ZA881139B (ko)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743607A (en) * 1987-05-29 1988-05-10 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic imidazolones
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
US5308845A (en) * 1988-12-22 1994-05-03 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
PT99864B (pt) 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
DK73091D0 (da) * 1991-04-22 1991-04-22 Novo Nordisk As Quinoxalinforbindelser, deres fremstilling og anvendelse
DE69224069T2 (de) * 1991-09-09 1998-07-02 Warner-Lambert Co., Ann Arbor, Mich. Pharmazeutisches kombinationspräparat, das ein uricosurisches mittel und einen excitatorischen aminosäure-antagonisten enthält
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
ES2313714T3 (es) * 1992-06-22 2009-03-01 The Regents Of The University Of California Antagonistas de receptores de glicina y uso de los mismos.
EP0664807B1 (en) * 1992-10-13 1997-09-10 Warner-Lambert Company Quinoxalinedione derivatives as eaa antagonists
DK12293D0 (da) * 1993-02-02 1993-02-02 Novo Nordisk As Heterocykliske forbindelser og deres fremstilling og anvendelse
ATE161259T1 (de) * 1993-05-13 1998-01-15 Neurosearch As Ampa antagonisten und behandlungsmethode
US5843945A (en) * 1993-05-13 1998-12-01 Neurosearch A/S AMPA antagonists and a method of treatment
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
GB9419318D0 (en) * 1994-09-24 1994-11-09 Pfizer Ltd Therapeutic agents
DE4436852A1 (de) * 1994-10-14 1996-04-18 Basf Ag Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
WO1996017832A1 (en) * 1994-12-07 1996-06-13 Warner-Lambert Company Novel glutamate receptor antagonists: fused cycloalkylquinoxalinediones
US5721234A (en) * 1994-12-07 1998-02-24 Warner-Lambert Company Glutamate receptor antagonists: fused cycloalkylouinoxalinediones
EP0809624B1 (en) * 1995-02-15 2001-08-29 Bearsden Bio, Inc. Alkylcarboxy amino acids-modulators of the kainate receptor
AU4423496A (en) * 1995-03-14 1996-10-02 Warner-Lambert Company Novel glutamate (ampa/kainate) receptor antagonists: n-substituted fused azacycloalkylquinoxalinediones
US5719153A (en) * 1995-08-15 1998-02-17 American Home Products Corporation 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones
WO1998005651A1 (en) * 1996-08-01 1998-02-12 Warner-Lambert Company Novel glutamate receptor antagonists: fused cycloalkyl quinoxalinediones
FR2752163B1 (fr) * 1996-08-12 1998-10-30 Pf Medicament Utilisation de l'efaroxan pour la fabricaton de medicament destine au traitement de la maladie de huntington
US5968928A (en) * 1996-09-19 1999-10-19 Warner-Lambert Company Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions
EP4403185A1 (en) 2021-09-15 2024-07-24 University of The Ryukyus Pharmaceutical composition for treating cognitive decline or for treating overweightness or obesity
WO2023042887A1 (ja) 2021-09-15 2023-03-23 国立大学法人 琉球大学 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431111A (en) * 1963-06-10 1969-03-04 Eastman Kodak Co Cyanine dyes
US3772273A (en) * 1969-01-17 1973-11-13 Allied Chem Derivatives of quinoxaline
US3962440A (en) * 1973-12-26 1976-06-08 Eli Lilly And Company Quinoxaline compounds as hypnotic agents
US4430502A (en) * 1982-08-13 1984-02-07 The Upjohn Company Pyridinyl substituted benzimidazoles and quinoxalines
FR2583751B1 (fr) * 1985-06-20 1989-10-13 Panmedica Nouveaux antibacteriens contenant des derives des acides oxo-4-pyridine carboxyliques et leur procede de preparation

Also Published As

Publication number Publication date
EP0283959B1 (en) 1992-01-02
ATE71090T1 (de) 1992-01-15
US4889855A (en) 1989-12-26
DK146787D0 (da) 1987-03-23
AU1326088A (en) 1988-09-22
US4912108A (en) 1990-03-27
NO881264D0 (no) 1988-03-22
IL85328A (en) 1993-06-10
NO174549C (no) 1994-05-25
DE3867268D1 (de) 1992-02-13
NO881264L (no) 1988-09-26
FI92582C (fi) 1994-12-12
IE60002B1 (en) 1994-05-18
AU596737B2 (en) 1990-05-10
KR880011125A (ko) 1988-10-26
FI880816A0 (fi) 1988-02-22
CA1315789C (en) 1993-04-06
PT87063B (pt) 1992-07-31
NO174549B (no) 1994-02-14
FI880816A (fi) 1988-09-24
PT87063A (pt) 1988-04-01
ES2037753T3 (es) 1993-07-01
GR3003910T3 (ko) 1993-03-16
KR960003324B1 (ko) 1996-03-08
FI92582B (fi) 1994-08-31
ZA881139B (en) 1988-08-15
NZ223776A (en) 1990-10-26
EP0283959A1 (en) 1988-09-28
IE880439L (en) 1988-09-23
PH23979A (en) 1990-02-09

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
PBP Patent lapsed