DK356788D0 - Heterocykliske forbindelser, deres fremstilling og anvendelse - Google Patents

Heterocykliske forbindelser, deres fremstilling og anvendelse

Info

Publication number
DK356788D0
DK356788D0 DK356788A DK356788A DK356788D0 DK 356788 D0 DK356788 D0 DK 356788D0 DK 356788 A DK356788 A DK 356788A DK 356788 A DK356788 A DK 356788A DK 356788 D0 DK356788 D0 DK 356788D0
Authority
DK
Denmark
Prior art keywords
compounds
preparation
heterocyclic compounds
hydrogen
so2nh2
Prior art date
Application number
DK356788A
Other languages
English (en)
Other versions
DK160941B (da
DK356788A (da
DK160941C (da
Inventor
Poul Jacobsen
Flemming Elmelund Nielsen
Tage Honore
Joergen Drejer
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan As filed Critical Ferrosan As
Publication of DK356788D0 publication Critical patent/DK356788D0/da
Priority to DK356788A priority Critical patent/DK160941C/da
Priority to IE200889A priority patent/IE64289B1/en
Priority to US07/369,762 priority patent/US4977155A/en
Priority to IL9073389A priority patent/IL90733A/en
Priority to CA000603702A priority patent/CA1326670C/en
Priority to ES89111622T priority patent/ES2059636T3/es
Priority to EP89111622A priority patent/EP0348872B1/en
Priority to DE89111622T priority patent/DE68909513T2/de
Priority to AT89111622T priority patent/ATE95181T1/de
Priority to NZ229730A priority patent/NZ229730A/en
Priority to AU37077/89A priority patent/AU619863B2/en
Priority to NO892680A priority patent/NO169390C/no
Priority to ZA894903A priority patent/ZA894903B/xx
Priority to KR1019890008933A priority patent/KR910000735A/ko
Priority to PT91010A priority patent/PT91010B/pt
Priority to JP1164091A priority patent/JPH0248578A/ja
Priority to FI893170A priority patent/FI91259C/fi
Priority to PH38872A priority patent/PH27565A/en
Publication of DK356788A publication Critical patent/DK356788A/da
Priority to US07/570,019 priority patent/US5075306A/en
Priority to US07/570,903 priority patent/US5057516A/en
Priority to US07/570,819 priority patent/US5109001A/en
Priority to US07/572,172 priority patent/US5079250A/en
Publication of DK160941B publication Critical patent/DK160941B/da
Application granted granted Critical
Publication of DK160941C publication Critical patent/DK160941C/da
Priority to FI931891A priority patent/FI93838C/fi
Priority to FI931894A priority patent/FI93839C/fi
Priority to FI931893A priority patent/FI93840C/fi
Priority to FI931892A priority patent/FI93841C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK356788A 1988-06-28 1988-06-28 Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar DK160941C (da)

Priority Applications (26)

Application Number Priority Date Filing Date Title
DK356788A DK160941C (da) 1988-06-28 1988-06-28 Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
IE200889A IE64289B1 (en) 1988-06-28 1989-06-21 Heterocyclic compounds and their preparation and use
US07/369,762 US4977155A (en) 1988-06-28 1989-06-22 1,2,3-triazolo compounds
IL9073389A IL90733A (en) 1988-06-28 1989-06-23 Pharmaceutical preparations containing 2,3-new dihydroxyquinoxals and certain new compounds of this type
CA000603702A CA1326670C (en) 1988-06-28 1989-06-23 Fused 2,3-dihydroxypyrazines their preparation and use
ES89111622T ES2059636T3 (es) 1988-06-28 1989-06-26 Compuestos heterociclicos y su preparacion y empleo.
EP89111622A EP0348872B1 (en) 1988-06-28 1989-06-26 Fused dihydroxyquinoxalines and their use as glutamate antagonists
DE89111622T DE68909513T2 (de) 1988-06-28 1989-06-26 Kondensierte Dihydroxychinoxaline und ihre Verwendung als Glutamatantagonisten.
AT89111622T ATE95181T1 (de) 1988-06-28 1989-06-26 Kondensierte dihydroxychinoxaline und ihre verwendung als glutamatantagonisten.
NZ229730A NZ229730A (en) 1988-06-28 1989-06-27 Substituted fused quinoxaline derivatives: pharmaceutical compositions and methods of treatment
AU37077/89A AU619863B2 (en) 1988-06-28 1989-06-27 Fused 2,3-dihydroxypyrazines and their preparation and use
NO892680A NO169390C (no) 1988-06-28 1989-06-27 Analogifremgangsmaate for fremstilling av terapeutisk aktive kinoxalinderivater
KR1019890008933A KR910000735A (ko) 1988-06-28 1989-06-28 융합된 2, 3-디하이드록시피라진 및 이의 제조방법
PH38872A PH27565A (en) 1988-06-28 1989-06-28 Fused 2,3-dihydropyrazines there preparation and use
ZA894903A ZA894903B (en) 1988-06-28 1989-06-28 Fused 2,3-dihydroxypyrazines,their preparation and use
PT91010A PT91010B (pt) 1988-06-28 1989-06-28 Processo de preparacao de derivados substituidos de quinoxalina
JP1164091A JPH0248578A (ja) 1988-06-28 1989-06-28 複素環式化合物、その製造方法並びにその使用
FI893170A FI91259C (fi) 1988-06-28 1989-06-28 Menetelmä uusien terapeuttisesti käyttökelpoisten 1,2,3-triatsolo/4,5-f/kinoksaliinijohdannaisten valmistamiseksi
US07/570,019 US5075306A (en) 1988-06-28 1990-08-20 Thiazoloquinoxalines
US07/570,903 US5057516A (en) 1988-06-28 1990-08-22 7,8-dihydroxy-1H-pyrazolo[3,4-f]quinoxalines
US07/570,819 US5109001A (en) 1988-06-28 1990-08-22 Fused 2,3-dihydroxydiazolo compounds and their preparation and use
US07/572,172 US5079250A (en) 1988-06-28 1990-08-23 Tricyclic heterocyclic diols and their preparation and use
FI931892A FI93841C (fi) 1988-06-28 1993-04-27 Menetelmä uusien terapeuttisesti käyttökelpoisten tiatsolo/5,4-f/- ja tieno/3,2-f/kinoksaliinijohdannaisten valmistamiseksi
FI931891A FI93838C (fi) 1988-06-28 1993-04-27 Menetelmä uusien terapeuttisesti käyttökelpoisten 7,8-dihydroksi-1H-imidatso- ja pyratsolo/3,4-f/kinoksaliinijohdannaisten valmistamiseksi
FI931894A FI93839C (fi) 1988-06-28 1993-04-27 Menetelmä uusien terapeuttisesti käyttökelpoisten 2,3-dihydroksi-pyratsino/2,3-f/kinoksaliini- ja pyratsino/2,3-g//1,5/bentsodiatsepiinijohdannaisten valmistamiseksi
FI931893A FI93840C (fi) 1988-06-28 1993-04-27 Menetelmä uusien terapeuttisesti käyttökelpoisten 7,8-dihydroksi-1,2,5-oksa-, tia- ja seleenidiatsolo/3,4-f/kinoksaliinijohdannaisten valmistamiseksi

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK356788 1988-06-28
DK356788A DK160941C (da) 1988-06-28 1988-06-28 Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar

Publications (4)

Publication Number Publication Date
DK356788D0 true DK356788D0 (da) 1988-06-28
DK356788A DK356788A (da) 1990-03-21
DK160941B DK160941B (da) 1991-05-06
DK160941C DK160941C (da) 1991-10-21

Family

ID=8124358

Family Applications (1)

Application Number Title Priority Date Filing Date
DK356788A DK160941C (da) 1988-06-28 1988-06-28 Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar

Country Status (18)

Country Link
US (5) US4977155A (da)
EP (1) EP0348872B1 (da)
JP (1) JPH0248578A (da)
KR (1) KR910000735A (da)
AT (1) ATE95181T1 (da)
AU (1) AU619863B2 (da)
CA (1) CA1326670C (da)
DE (1) DE68909513T2 (da)
DK (1) DK160941C (da)
ES (1) ES2059636T3 (da)
FI (1) FI91259C (da)
IE (1) IE64289B1 (da)
IL (1) IL90733A (da)
NO (1) NO169390C (da)
NZ (1) NZ229730A (da)
PH (1) PH27565A (da)
PT (1) PT91010B (da)
ZA (1) ZA894903B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
US5153195A (en) * 1988-12-22 1992-10-06 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
PT99864B (pt) 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
US5196421A (en) * 1991-06-05 1993-03-23 Eli Lilly And Company Excitatory amino acid receptor antagonists in methods for the use thereof
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
DK162491D0 (da) * 1991-09-20 1991-09-20 Novo Nordisk As Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
ATE404201T1 (de) * 1992-06-22 2008-08-15 Univ California Glycinrezeptorantagonisten und ihre verwendung
EP0664807B1 (en) 1992-10-13 1997-09-10 Warner-Lambert Company Quinoxalinedione derivatives as eaa antagonists
DE4310523A1 (de) * 1993-03-31 1994-10-06 Basf Ag Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
US5576323A (en) * 1993-12-03 1996-11-19 Eli Lilly And Company Excitatory amino acid receptor antagonists
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative
US5476851A (en) * 1994-09-08 1995-12-19 Rhone-Poulenc Rorer Pharmaceuticals, Inc. Pyrazolo[3,4-g]quinoxaline compounds which inhibit PDGF receptor protein tyrosine kinase
US5719153A (en) * 1995-08-15 1998-02-17 American Home Products Corporation 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
WO1998013046A1 (en) 1996-09-27 1998-04-02 Guilford Pharmaceuticals Inc. Naaladase compositions and methods for treating glutamate abnormality and effecting neuronal activity in animals
WO1998032439A1 (en) 1997-01-23 1998-07-30 Smithkline Beecham Corporation Il-8 receptor antagonists
FR2760237B1 (fr) * 1997-02-28 1999-04-16 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
US6288075B1 (en) 1998-02-26 2001-09-11 Rhone-Poulenc Rorer S.A. Thiazolo[5,4,3-ij]quinolines, preparation and medicines containing the same
FR2766487B1 (fr) * 1997-07-28 1999-08-27 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
WO1999046267A1 (en) * 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
US6262044B1 (en) 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
JP2009286778A (ja) * 2008-04-30 2009-12-10 Sumitomo Chemical Co Ltd ｔｅｒｔ−ブチル３−アミノピペリジン−１−カルボキシレートの製造方法およびその中間体
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions
CN113549087A (zh) * 2020-04-26 2021-10-26 北京鼎材科技有限公司 一种化合物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1246578A (en) * 1982-03-29 1988-12-13 John H. Musser 2-oxo-1,3-oxazolo[4,5]quinolines useful as anti-allergy agents
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
US5109001A (en) 1992-04-28
DK160941B (da) 1991-05-06
FI893170A (fi) 1989-12-29
AU619863B2 (en) 1992-02-06
CA1326670C (en) 1994-02-01
KR910000735A (ko) 1991-01-30
NO892680L (no) 1989-12-29
PT91010A (pt) 1989-12-29
DK356788A (da) 1990-03-21
IE64289B1 (en) 1995-07-26
FI91259C (fi) 1994-06-10
US5079250A (en) 1992-01-07
FI893170A0 (fi) 1989-06-28
EP0348872B1 (en) 1993-09-29
US4977155A (en) 1990-12-11
NO169390C (no) 1992-06-17
ES2059636T3 (es) 1994-11-16
IE892008L (en) 1989-12-28
DK160941C (da) 1991-10-21
NZ229730A (en) 1991-07-26
NO169390B (no) 1992-03-09
US5057516A (en) 1991-10-15
DE68909513D1 (de) 1993-11-04
PT91010B (pt) 1995-01-31
PH27565A (en) 1993-08-18
NO892680D0 (no) 1989-06-27
IL90733A0 (en) 1990-01-18
ZA894903B (en) 1990-03-28
IL90733A (en) 1994-02-27
JPH0248578A (ja) 1990-02-19
DE68909513T2 (de) 1994-01-20
ATE95181T1 (de) 1993-10-15
AU3707789A (en) 1990-01-04
EP0348872A1 (en) 1990-01-03
FI91259B (fi) 1994-02-28
US5075306A (en) 1991-12-24

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