ZA894903B - Fused 2,3-dihydroxypyrazines,their preparation and use - Google Patents

Fused 2,3-dihydroxypyrazines,their preparation and use

Info

Publication number
ZA894903B
ZA894903B ZA894903A ZA894903A ZA894903B ZA 894903 B ZA894903 B ZA 894903B ZA 894903 A ZA894903 A ZA 894903A ZA 894903 A ZA894903 A ZA 894903A ZA 894903 B ZA894903 B ZA 894903B
Authority
ZA
South Africa
Prior art keywords
compounds
dihydroxypyrazines
fused
preparation
hydrogen
Prior art date
Application number
ZA894903A
Other languages
English (en)
Inventor
Poul Jocobsen
Jocobsen Poul
Flemming Elmelund Nielsen
Elmelund Nielsen Flemming
Tage Honore
Honore Tage
Joergen Dreijer
Dreijer Joergen
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan As filed Critical Ferrosan As
Publication of ZA894903B publication Critical patent/ZA894903B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Luminescent Compositions (AREA)
ZA894903A 1988-06-28 1989-06-28 Fused 2,3-dihydroxypyrazines,their preparation and use ZA894903B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK356788A DK160941C (da) 1988-06-28 1988-06-28 Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar

Publications (1)

Publication Number Publication Date
ZA894903B true ZA894903B (en) 1990-03-28

Family

ID=8124358

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894903A ZA894903B (en) 1988-06-28 1989-06-28 Fused 2,3-dihydroxypyrazines,their preparation and use

Country Status (18)

Country Link
US (5) US4977155A (xx)
EP (1) EP0348872B1 (xx)
JP (1) JPH0248578A (xx)
KR (1) KR910000735A (xx)
AT (1) ATE95181T1 (xx)
AU (1) AU619863B2 (xx)
CA (1) CA1326670C (xx)
DE (1) DE68909513T2 (xx)
DK (1) DK160941C (xx)
ES (1) ES2059636T3 (xx)
FI (1) FI91259C (xx)
IE (1) IE64289B1 (xx)
IL (1) IL90733A (xx)
NO (1) NO169390C (xx)
NZ (1) NZ229730A (xx)
PH (1) PH27565A (xx)
PT (1) PT91010B (xx)
ZA (1) ZA894903B (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153195A (en) * 1988-12-22 1992-10-06 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
PT99864B (pt) 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
US5196421A (en) * 1991-06-05 1993-03-23 Eli Lilly And Company Excitatory amino acid receptor antagonists in methods for the use thereof
DK162491D0 (da) * 1991-09-20 1991-09-20 Novo Nordisk As Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
DE69334237D1 (de) * 1992-06-22 2008-09-25 State Of Oregon Through Oregon Glycinrezeptorantagonisten und ihre verwendung
DE69313866T2 (de) 1992-10-13 1998-03-05 Warner Lambert Co Chinoxalinderivate als eaa antagonisten
DE4310523A1 (de) * 1993-03-31 1994-10-06 Basf Ag Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
US5576323A (en) * 1993-12-03 1996-11-19 Eli Lilly And Company Excitatory amino acid receptor antagonists
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative
US5476851A (en) * 1994-09-08 1995-12-19 Rhone-Poulenc Rorer Pharmaceuticals, Inc. Pyrazolo[3,4-g]quinoxaline compounds which inhibit PDGF receptor protein tyrosine kinase
US5719153A (en) * 1995-08-15 1998-02-17 American Home Products Corporation 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
AU733880B2 (en) 1996-09-27 2001-05-31 Eisai Inc. Naaladase compositions and methods for treating glutamate abnormality and effecting neuronal activity in animals
TR199901710T2 (xx) * 1997-01-23 1999-09-21 Smithkline Beecham Corporation IL-8 resept�r antagonistleri.
US6288075B1 (en) 1998-02-26 2001-09-11 Rhone-Poulenc Rorer S.A. Thiazolo[5,4,3-ij]quinolines, preparation and medicines containing the same
FR2760237B1 (fr) * 1997-02-28 1999-04-16 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
FR2766487B1 (fr) * 1997-07-28 1999-08-27 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
US6262044B1 (en) 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
WO1999046267A1 (en) * 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
JP2009286778A (ja) * 2008-04-30 2009-12-10 Sumitomo Chemical Co Ltd ｔｅｒｔ−ブチル３−アミノピペリジン−１−カルボキシレートの製造方法およびその中間体
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions
CN113549087A (zh) * 2020-04-26 2021-10-26 北京鼎材科技有限公司 一种化合物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1246578A (en) * 1982-03-29 1988-12-13 John H. Musser 2-oxo-1,3-oxazolo[4,5]quinolines useful as anti-allergy agents
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
NO892680D0 (no) 1989-06-27
DK356788D0 (da) 1988-06-28
AU3707789A (en) 1990-01-04
EP0348872A1 (en) 1990-01-03
DK160941B (da) 1991-05-06
PH27565A (en) 1993-08-18
NO169390B (no) 1992-03-09
DK356788A (da) 1990-03-21
NZ229730A (en) 1991-07-26
PT91010B (pt) 1995-01-31
NO169390C (no) 1992-06-17
ATE95181T1 (de) 1993-10-15
AU619863B2 (en) 1992-02-06
JPH0248578A (ja) 1990-02-19
ES2059636T3 (es) 1994-11-16
NO892680L (no) 1989-12-29
KR910000735A (ko) 1991-01-30
DK160941C (da) 1991-10-21
IL90733A (en) 1994-02-27
FI91259C (fi) 1994-06-10
US4977155A (en) 1990-12-11
IE64289B1 (en) 1995-07-26
US5057516A (en) 1991-10-15
US5079250A (en) 1992-01-07
CA1326670C (en) 1994-02-01
US5075306A (en) 1991-12-24
PT91010A (pt) 1989-12-29
DE68909513T2 (de) 1994-01-20
IE892008L (en) 1989-12-28
US5109001A (en) 1992-04-28
FI893170A (fi) 1989-12-29
DE68909513D1 (de) 1993-11-04
FI91259B (fi) 1994-02-28
EP0348872B1 (en) 1993-09-29
FI893170A0 (fi) 1989-06-28
IL90733A0 (en) 1990-01-18

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