DK1458697T3 - Biphenylmethylthiazolidindioner og dermed analoge forbindelser og deres anvendelse som PPAR-gamma-aktivatorer - Google Patents
Biphenylmethylthiazolidindioner og dermed analoge forbindelser og deres anvendelse som PPAR-gamma-aktivatorerInfo
- Publication number
- DK1458697T3 DK1458697T3 DK02805790T DK02805790T DK1458697T3 DK 1458697 T3 DK1458697 T3 DK 1458697T3 DK 02805790 T DK02805790 T DK 02805790T DK 02805790 T DK02805790 T DK 02805790T DK 1458697 T3 DK1458697 T3 DK 1458697T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- aryl
- aralkyl
- phenyl
- benzothiazolyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0116750A FR2833949B1 (fr) | 2001-12-21 | 2001-12-21 | NOUVEAUX LIGANDS ACTIVATEURS DES RECEPTEURS PPARy, LEUR PROCEDE DE PREPARATION ET LEUR UTILISATION EN MEDECINE HUMAINE AINSI QU'EN COSMETIQUE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1458697T3 true DK1458697T3 (da) | 2007-01-15 |
Family
ID=8870902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02805790T DK1458697T3 (da) | 2001-12-21 | 2002-12-09 | Biphenylmethylthiazolidindioner og dermed analoge forbindelser og deres anvendelse som PPAR-gamma-aktivatorer |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1458697B1 (pt) |
| JP (1) | JP2005518394A (pt) |
| KR (1) | KR20040072676A (pt) |
| CN (1) | CN100360512C (pt) |
| AT (1) | ATE338753T1 (pt) |
| AU (1) | AU2002364985A1 (pt) |
| BR (1) | BR0214239A (pt) |
| CA (1) | CA2468796C (pt) |
| CY (1) | CY1106255T1 (pt) |
| DE (1) | DE60214595T2 (pt) |
| DK (1) | DK1458697T3 (pt) |
| ES (1) | ES2272820T3 (pt) |
| FR (1) | FR2833949B1 (pt) |
| HU (1) | HUP0402616A3 (pt) |
| MX (1) | MXPA04006051A (pt) |
| PL (1) | PL372881A1 (pt) |
| PT (1) | PT1458697E (pt) |
| RU (1) | RU2323212C2 (pt) |
| WO (1) | WO2003055867A1 (pt) |
| ZA (1) | ZA200403797B (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI311133B (en) | 2001-04-20 | 2009-06-21 | Eisai R&D Man Co Ltd | Carboxylic acid derivativeand the salt thereof |
| JPWO2002098840A1 (ja) | 2001-06-04 | 2004-09-16 | エーザイ株式会社 | カルボン酸誘導体及びその塩もしくはそのエステルからなる医薬 |
| JP2006516550A (ja) * | 2002-11-25 | 2006-07-06 | ガルデルマ・リサーチ・アンド・デヴェロップメント・エス・エヌ・セ | ＰＰＡＲγ＋タイプ受容体を活性化する新規な二芳香族化合物および化粧品組成物または医薬組成物でのその使用 |
| ATE458485T1 (de) | 2003-07-11 | 2010-03-15 | Proteologics Inc | Ubiquitin-ligase-hemmer und verwandte verfahren |
| FR2862870A1 (fr) * | 2003-12-01 | 2005-06-03 | Galderma Res & Dev | Utilisation d'activateurs de recepteurs ppar en cosmetique et dermatologie. |
| EP1734963A4 (en) | 2004-04-02 | 2008-06-18 | Merck & Co Inc | METHOD FOR TREATING PEOPLE WITH METABOLIC AND ANTHROPOMETRIC DISORDER |
| CA2575039A1 (en) | 2004-08-11 | 2006-02-16 | Kyorin Pharmaceutical Co., Ltd. | Novel cyclic amino benzoic acid derivative |
| FR2874378B1 (fr) * | 2004-08-17 | 2006-10-27 | Galderma Res & Dev | Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppar et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
| CA2575029C (en) * | 2004-08-17 | 2013-11-12 | Galderma Research & Development, S.N.C. | Novel biaromatic compounds which activate receptors of ppar type and their use in cosmetic or pharmaceutical compositions |
| DE602005010444D1 (de) * | 2004-08-17 | 2008-11-27 | Galderma Res & Dev | Neuartige biaromatische ppar-rezeptoren aktivierende zusammensetzungen und ihre verwendung in kosmetischen oder pharmazeutischen zusammensetzungen |
| FR2874379B1 (fr) * | 2004-08-17 | 2006-10-27 | Galderma Res & Dev | Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppar et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
| MX2007006014A (es) * | 2004-11-19 | 2007-11-14 | Galderma Res & Dev | Compuestos que modulan receptores tipo ppar-gamma y uso de los mismos en composiciones cosmeticas y farmaceuticas. |
| FR2878247B1 (fr) | 2004-11-19 | 2008-10-03 | Galderma Res & Dev | Nouveaux composes modulateurs des recepteurs de type ppary et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
| FR2887444A1 (fr) * | 2005-06-28 | 2006-12-29 | Oreal | Composes benzylidene-1,3-thiazolidine-2,4-diones, leurs utilisations et compositions pour stimuler ou induire la pousse des fibres keratiniques et/ou freiner leur chute et/ou augmenter leur densite. |
| FR2892412B1 (fr) | 2005-10-26 | 2008-05-16 | Galderma Res & Dev | Composes biaromatiques modulateurs des ppars |
| EP2998314B1 (en) | 2007-06-04 | 2020-01-22 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8034782B2 (en) | 2008-07-16 | 2011-10-11 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| FR2917086B1 (fr) * | 2007-06-05 | 2009-07-17 | Galderma Res & Dev | Nouveaux derives d'acide 3-phenyl acrylique activateurs des recepteurs de type ppar, leur methode de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques. |
| FR2917084B1 (fr) * | 2007-06-05 | 2009-07-17 | Galderma Res & Dev | Nouveaux derives d'acide 3-phenyl propanoique activateurs des recpteurs de type ppar, leur methode de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques. |
| IE20070928A1 (en) * | 2007-12-21 | 2009-09-30 | Giuliani Int Ltd | Multi target ligands |
| ES2627848T3 (es) | 2008-06-04 | 2017-07-31 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| CN101774941A (zh) | 2009-01-13 | 2010-07-14 | 浙江九洲药业股份有限公司 | 2-酰基氨基-3-联苯基丙酸的制备及拆分方法 |
| WO2012027331A1 (en) | 2010-08-27 | 2012-03-01 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| PL3004138T3 (pl) | 2013-06-05 | 2024-07-29 | Bausch Health Ireland Limited | Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie |
| CN118206473A (zh) * | 2023-03-22 | 2024-06-18 | 沈阳药科大学 | 一种化合物及其制备方法和在制备sEH抑制剂与PPARs激动剂中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2767525B1 (fr) * | 1997-08-21 | 1999-11-12 | Cird Galderma | Derives biphenyliques substitues par un radical aromatique ou heteroaromatique et compositions pharmaceutiques et cosmetiques les contenant |
| ATE451346T1 (de) * | 1998-03-10 | 2009-12-15 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| CN1155586C (zh) * | 1999-08-23 | 2004-06-30 | 杏林制药株式会社 | 取代的苄基噻唑烷-2,4-二酮衍生物 |
| FR2812876B1 (fr) * | 2000-08-08 | 2002-09-27 | Galderma Res & Dev | Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppar-gamma et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
-
2001
- 2001-12-21 FR FR0116750A patent/FR2833949B1/fr not_active Expired - Fee Related
-
2002
- 2002-12-09 CA CA2468796A patent/CA2468796C/fr not_active Expired - Fee Related
- 2002-12-09 DK DK02805790T patent/DK1458697T3/da active
- 2002-12-09 RU RU2004122394/04A patent/RU2323212C2/ru not_active IP Right Cessation
- 2002-12-09 BR BR0214239-2A patent/BR0214239A/pt not_active IP Right Cessation
- 2002-12-09 JP JP2003556398A patent/JP2005518394A/ja not_active Withdrawn
- 2002-12-09 AU AU2002364985A patent/AU2002364985A1/en not_active Abandoned
- 2002-12-09 KR KR10-2004-7009903A patent/KR20040072676A/ko not_active Application Discontinuation
- 2002-12-09 WO PCT/FR2002/004232 patent/WO2003055867A1/fr active IP Right Grant
- 2002-12-09 CN CNB028254899A patent/CN100360512C/zh not_active Expired - Fee Related
- 2002-12-09 DE DE60214595T patent/DE60214595T2/de not_active Expired - Lifetime
- 2002-12-09 AT AT02805790T patent/ATE338753T1/de not_active IP Right Cessation
- 2002-12-09 MX MXPA04006051A patent/MXPA04006051A/es active IP Right Grant
- 2002-12-09 ES ES02805790T patent/ES2272820T3/es not_active Expired - Lifetime
- 2002-12-09 PL PL02372881A patent/PL372881A1/xx not_active Application Discontinuation
- 2002-12-09 HU HU0402616A patent/HUP0402616A3/hu unknown
- 2002-12-09 EP EP02805790A patent/EP1458697B1/fr not_active Expired - Lifetime
- 2002-12-09 PT PT02805790T patent/PT1458697E/pt unknown
-
2004
- 2004-05-18 ZA ZA200403797A patent/ZA200403797B/en unknown
-
2006
- 2006-11-23 CY CY20061101695T patent/CY1106255T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE338753T1 (de) | 2006-09-15 |
| FR2833949B1 (fr) | 2005-08-05 |
| EP1458697B1 (fr) | 2006-09-06 |
| HUP0402616A2 (hu) | 2005-03-29 |
| KR20040072676A (ko) | 2004-08-18 |
| CN100360512C (zh) | 2008-01-09 |
| CA2468796A1 (fr) | 2003-07-10 |
| HUP0402616A3 (en) | 2009-01-28 |
| BR0214239A (pt) | 2004-09-21 |
| CA2468796C (fr) | 2012-07-17 |
| MXPA04006051A (es) | 2004-09-27 |
| RU2323212C2 (ru) | 2008-04-27 |
| CY1106255T1 (el) | 2011-06-08 |
| DE60214595T2 (de) | 2007-09-13 |
| FR2833949A1 (fr) | 2003-06-27 |
| ZA200403797B (en) | 2004-12-22 |
| RU2004122394A (ru) | 2005-03-27 |
| AU2002364985A1 (en) | 2003-07-15 |
| CN1639138A (zh) | 2005-07-13 |
| PL372881A1 (en) | 2005-08-08 |
| EP1458697A1 (fr) | 2004-09-22 |
| DE60214595D1 (de) | 2006-10-19 |
| PT1458697E (pt) | 2007-01-31 |
| JP2005518394A (ja) | 2005-06-23 |
| WO2003055867A1 (fr) | 2003-07-10 |
| ES2272820T3 (es) | 2007-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1458697T3 (da) | Biphenylmethylthiazolidindioner og dermed analoge forbindelser og deres anvendelse som PPAR-gamma-aktivatorer | |
| AR036115A1 (es) | Compuesto de n-aroilaminas, composiciones farmaceuticas formuladas con dichos compuestos; uso de los compuestos mencionados en la preparacion de composiciones farmaceuticas para tratar,prevenir enfermedades o trastornos donde se requiere la aplicacion de antagonistas de receptores de la orexina huma | |
| PE20050142A1 (es) | 2-hidroxi-3-diaminoalcanos de benzamida | |
| ATE167482T1 (de) | Peptidbindungen enthaltende essigsäurederivate | |
| RS51444B (sr) | JEDINJENJA KOJA SADRŽE LAKTAM I NJIHOVI DERIVATI KAO INHIBITORI FAKTORA Xa | |
| ATE213727T1 (de) | In position 3 durch eine stickstoffgruppe substituierte 1,3-dihydroindol-2-on derivate als vasopressin und/oder ocytocin agonisten und/oder antagonisten | |
| ATE269312T1 (de) | N-(amidinophenyl)-n'-(subst.)-3h-2,4- benzodiazepin-3-on derivative als faktor xa inhibitoren | |
| KR960014121A (ko) | 아로일-피페리딘 유도체 | |
| UA41251C2 (uk) | Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі | |
| WO2002038553A3 (en) | Triazole derivatives and their use as peroxisome proliferator activated receptor alpha agonists | |
| HRP20090162T1 (en) | Quinolinone-carboxamide compounds as 5-ht4 receptor agonists | |
| ES2052387T3 (es) | Utilizacion de derivados de pirimidina-3-oxido para frenar la caida de los cabellos y composiciones topicas empleadas. | |
| MXPA04006581A (es) | Derivados de sulfonato y su empleo como acidos latentes. | |
| BR0316607A (pt) | Derivados de hidroxifenil benzofenona substituìdos com amino | |
| ATE438396T1 (de) | Pyrrolopyridin-derivate und deren verwendung als ppar-rezeptormodulatoren | |
| DE69408962D1 (de) | Naphthalen-Derivate mit Affinität für Melatonin-Rezeptoren, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen | |
| DK1313716T3 (da) | Oxazolyl-arylpropionsyrederivater og anvendelse deraf som PPAR-agonister | |
| FR2850114B1 (fr) | Nouvelles compositions contenant des hydrocarbures fluores et des solvants oxygenes | |
| NO984047D0 (no) | Nye svovelderivater omfattende en amidbinding, metode for fremstilling av disse, anvendelse derav som legemidler og farmas°ytiske preparater inneholdende slike derivater | |
| JP2007512259A5 (pt) | ||
| DK1219621T3 (da) | Azaindolizinonderivater og cerebral funktionsforbedrende midler indeholdende disse som den aktive bestanddel | |
| ATE239034T1 (de) | Mechanismus-orientierte inhibitoren der dipeptidylpeptidase i | |
| DE602004009306D1 (de) | 3,4-dihydro-1h-chinolin-2-onderivate als norepinephrin-wiederaufnahme-hemmern | |
| HRP20030653B1 (en) | Novel benzoylguanidine salt | |
| SE1050530T3 (sv) | 1-aza-2-alkyl-6-aryl-cykloalkaner anvaendbara som minnesfoerhoejande aemnen |