DK143278C - Analogifremgangsmaade til fremstilling af n-(r-tetrahydrofurfuryl)-noroxymorphon eller syreadditionssalte deraf - Google Patents
Analogifremgangsmaade til fremstilling af n-(r-tetrahydrofurfuryl)-noroxymorphon eller syreadditionssalte derafInfo
- Publication number
- DK143278C DK143278C DK386876A DK386876A DK143278C DK 143278 C DK143278 C DK 143278C DK 386876 A DK386876 A DK 386876A DK 386876 A DK386876 A DK 386876A DK 143278 C DK143278 C DK 143278C
- Authority
- DK
- Denmark
- Prior art keywords
- noroxymorphone
- tetrahydrofurfuryl
- analogue
- preparation
- acid addition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752538075 DE2538075A1 (de) | 1975-08-27 | 1975-08-27 | N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung |
| DE2538075 | 1975-08-27 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK386876A DK386876A (da) | 1977-02-28 |
| DK143278B DK143278B (da) | 1981-08-03 |
| DK143278C true DK143278C (da) | 1981-12-07 |
Family
ID=5954931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK386876A DK143278C (da) | 1975-08-27 | 1976-08-26 | Analogifremgangsmaade til fremstilling af n-(r-tetrahydrofurfuryl)-noroxymorphon eller syreadditionssalte deraf |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US4100288A (ro) |
| JP (1) | JPS5231100A (ro) |
| AT (1) | AT350737B (ro) |
| AU (1) | AU499926B2 (ro) |
| BE (1) | BE845563A (ro) |
| BG (2) | BG27546A4 (ro) |
| CA (1) | CA1068266A (ro) |
| CH (5) | CH622521A5 (ro) |
| CS (2) | CS192599B2 (ro) |
| DD (1) | DD127145A5 (ro) |
| DE (1) | DE2538075A1 (ro) |
| DK (1) | DK143278C (ro) |
| ES (5) | ES450897A1 (ro) |
| FI (1) | FI762430A (ro) |
| FR (1) | FR2321888A1 (ro) |
| GB (1) | GB1519719A (ro) |
| GR (1) | GR61158B (ro) |
| HU (1) | HU176929B (ro) |
| IE (1) | IE44069B1 (ro) |
| IL (1) | IL50355A (ro) |
| LU (1) | LU75667A1 (ro) |
| MX (1) | MX4133E (ro) |
| NL (1) | NL7609485A (ro) |
| NO (1) | NO145793C (ro) |
| NZ (1) | NZ181864A (ro) |
| PH (1) | PH13780A (ro) |
| PL (2) | PL110724B1 (ro) |
| PT (1) | PT65521B (ro) |
| RO (1) | RO69457A (ro) |
| SE (1) | SE7609495L (ro) |
| SU (2) | SU612631A3 (ro) |
| YU (1) | YU208176A (ro) |
| ZA (1) | ZA765120B (ro) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4272541A (en) * | 1978-06-02 | 1981-06-09 | Miles Laboratories, Inc. | 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them |
| US4272540A (en) * | 1979-04-24 | 1981-06-09 | Sisa, Incorporated | 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them |
| DE3220831A1 (de) * | 1982-06-03 | 1983-12-08 | Boehringer Ingelheim KG, 6507 Ingelheim | N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
| NZ572252A (en) * | 2006-04-21 | 2011-09-30 | Nektar Therapeutics | Stereoselective reduction of a morphinone |
| JP5728084B2 (ja) * | 2010-07-08 | 2015-06-03 | アルカーメス ファーマ アイルランド リミテッド | 置換モルフィナンの合成のための方法 |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| ES2770978T3 (es) | 2013-05-24 | 2020-07-06 | Alkermes Pharma Ireland Ltd | Análogos de morfanos y morfinanos y métodos de uso |
| WO2014190271A2 (en) | 2013-05-24 | 2014-11-27 | Alkermes Pharma Ireland Limted | Methods for treating depressive symptoms |
| MX2020008706A (es) * | 2018-02-23 | 2020-09-25 | Rhodes Tech | Nuevos compuestos de opioides y sus usos. |
| EP4243768A1 (en) | 2020-11-12 | 2023-09-20 | Alkermes Pharma Ireland Limited | Immediate release multilayer tablet |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH446370A (de) | 1964-03-05 | 1967-11-15 | Hoffmann La Roche | Verfahren zur Herstellung von Phenanthren-Derivaten |
| DE2238839A1 (de) * | 1972-08-07 | 1974-02-14 | Boehringer Sohn Ingelheim | Neue morphinon-derivate, deren saeureadditionssalze, verfahren zu ihrer herstellung sowie ihre verwendung zur herstellung von arzneimitteln |
-
1975
- 1975-08-27 DE DE19752538075 patent/DE2538075A1/de not_active Withdrawn
-
1976
- 1976-07-28 AT AT553976A patent/AT350737B/de not_active IP Right Cessation
- 1976-08-12 PH PH18780A patent/PH13780A/en unknown
- 1976-08-13 RO RO7687297A patent/RO69457A/ro unknown
- 1976-08-13 US US05/714,045 patent/US4100288A/en not_active Expired - Lifetime
- 1976-08-21 ES ES450897A patent/ES450897A1/es not_active Expired
- 1976-08-23 SU SU762389512A patent/SU612631A3/ru active
- 1976-08-24 FI FI762430A patent/FI762430A/fi not_active Application Discontinuation
- 1976-08-25 CS CS778646A patent/CS192599B2/cs unknown
- 1976-08-25 CH CH1079676A patent/CH622521A5/de not_active IP Right Cessation
- 1976-08-25 IL IL50355A patent/IL50355A/xx unknown
- 1976-08-25 BG BG7634743A patent/BG27546A4/xx unknown
- 1976-08-25 BG BG7634062A patent/BG27545A3/xx unknown
- 1976-08-25 CS CS765528A patent/CS192564B2/cs unknown
- 1976-08-25 DD DD194461A patent/DD127145A5/xx unknown
- 1976-08-26 JP JP51102168A patent/JPS5231100A/ja active Pending
- 1976-08-26 NZ NZ181864A patent/NZ181864A/xx unknown
- 1976-08-26 HU HU76BO1629A patent/HU176929B/hu unknown
- 1976-08-26 CA CA259,909A patent/CA1068266A/en not_active Expired
- 1976-08-26 MX MX764858U patent/MX4133E/es unknown
- 1976-08-26 SE SE7609495A patent/SE7609495L/xx not_active Application Discontinuation
- 1976-08-26 PT PT65521A patent/PT65521B/pt unknown
- 1976-08-26 NO NO762932A patent/NO145793C/no unknown
- 1976-08-26 LU LU75667A patent/LU75667A1/xx unknown
- 1976-08-26 BE BE170118A patent/BE845563A/xx unknown
- 1976-08-26 IE IE1911/76A patent/IE44069B1/en unknown
- 1976-08-26 YU YU02081/76A patent/YU208176A/xx unknown
- 1976-08-26 GR GR51547A patent/GR61158B/el unknown
- 1976-08-26 AU AU17201/76A patent/AU499926B2/en not_active Expired
- 1976-08-26 PL PL1976213963A patent/PL110724B1/pl unknown
- 1976-08-26 PL PL1976192020A patent/PL109091B1/pl unknown
- 1976-08-26 GB GB35603/76A patent/GB1519719A/en not_active Expired
- 1976-08-26 DK DK386876A patent/DK143278C/da active
- 1976-08-26 ZA ZA00765120A patent/ZA765120B/xx unknown
- 1976-08-26 NL NL7609485A patent/NL7609485A/xx not_active Application Discontinuation
- 1976-08-27 FR FR7625985A patent/FR2321888A1/fr active Granted
- 1976-12-09 ES ES454086A patent/ES454086A1/es not_active Expired
- 1976-12-09 ES ES454087A patent/ES454087A2/es not_active Expired
- 1976-12-09 ES ES454084A patent/ES454084A1/es not_active Expired
- 1976-12-09 ES ES454085A patent/ES454085A1/es not_active Expired
-
1977
- 1977-05-31 SU SU772485952A patent/SU638262A3/ru active
-
1980
- 1980-09-18 CH CH699580A patent/CH624116A5/de not_active IP Right Cessation
- 1980-09-18 CH CH699680A patent/CH624117A5/de not_active IP Right Cessation
- 1980-09-18 CH CH699380A patent/CH624114A5/de not_active IP Right Cessation
- 1980-09-18 CH CH699480A patent/CH624115A5/de not_active IP Right Cessation
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