DK141874B - Analogifremgangsmåde til fremstilling af D-6-alkyl-8-cyanmethylergolin-1'er eller farmaceutisk acceptable salte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af D-6-alkyl-8-cyanmethylergolin-1'er eller farmaceutisk acceptable salte deraf. Download PDF

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Publication number
DK141874B
DK141874B DK553376AA DK553376A DK141874B DK 141874 B DK141874 B DK 141874B DK 553376A A DK553376A A DK 553376AA DK 553376 A DK553376 A DK 553376A DK 141874 B DK141874 B DK 141874B
Authority
DK
Denmark
Prior art keywords
cyanomethylergoline
alkyl
mmol
general formula
acid
Prior art date
Application number
DK553376AA
Other languages
Danish (da)
English (en)
Other versions
DK553376A (de
DK141874C (de
Inventor
Antonin Cerny
Karel Rezabek
Miroslav Seda
Miroslav Semonsky
Rudolf Kotva
Marie Auskova
Original Assignee
Spofa Vereinigte Pharma Werke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Vereinigte Pharma Werke filed Critical Spofa Vereinigte Pharma Werke
Publication of DK553376A publication Critical patent/DK553376A/da
Publication of DK141874B publication Critical patent/DK141874B/da
Application granted granted Critical
Publication of DK141874C publication Critical patent/DK141874C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK553376AA 1975-12-12 1976-12-09 Analogifremgangsmåde til fremstilling af D-6-alkyl-8-cyanmethylergolin-1'er eller farmaceutisk acceptable salte deraf. DK141874B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CS758472A CS188414B1 (en) 1975-12-12 1975-12-12 New d-6-alkyl-8-cyanmethyl ergolines,their salts and method of producing
CS847275 1975-12-12

Publications (3)

Publication Number Publication Date
DK553376A DK553376A (de) 1977-06-13
DK141874B true DK141874B (da) 1980-07-07
DK141874C DK141874C (de) 1980-12-15

Family

ID=5435273

Family Applications (1)

Application Number Title Priority Date Filing Date
DK553376AA DK141874B (da) 1975-12-12 1976-12-09 Analogifremgangsmåde til fremstilling af D-6-alkyl-8-cyanmethylergolin-1'er eller farmaceutisk acceptable salte deraf.

Country Status (15)

Country Link
US (1) US4321380A (de)
JP (1) JPS5285195A (de)
AT (1) AT356293B (de)
AU (1) AU502928B2 (de)
BE (1) BE849318A (de)
CA (1) CA1069502A (de)
CH (1) CH622259A5 (de)
CS (1) CS188414B1 (de)
DE (1) DE2656093A1 (de)
DK (1) DK141874B (de)
FI (1) FI61189C (de)
FR (1) FR2334360A1 (de)
GB (1) GB1505800A (de)
NL (1) NL7613843A (de)
SE (1) SE419986B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3913756A1 (de) * 1989-04-21 1990-10-25 Schering Ag 8(beta)-substituierte ergoline, verfahren zu ihrer herstellung und ihre verwendung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE712054A (de) * 1967-03-16 1968-07-15
US3920664A (en) * 1972-07-21 1975-11-18 Lilly Co Eli D-2-halo-6-alkyl-8-substituted ergolines and related compounds
US3880856A (en) * 1973-06-29 1975-04-29 Lilly Co Eli Ergoline dimers
CS171480B1 (de) * 1974-03-19 1976-10-29
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
US3992385A (en) * 1975-01-20 1976-11-16 Eli Lilly And Company 2,3-Dihydroergolines

Also Published As

Publication number Publication date
FI61189B (fi) 1982-02-26
NL7613843A (nl) 1977-06-14
DE2656093A1 (de) 1977-06-23
GB1505800A (en) 1978-03-30
AT356293B (de) 1980-04-25
AU502928B2 (en) 1979-08-16
SE419986B (sv) 1981-09-07
FI763442A (de) 1977-06-13
US4321380A (en) 1982-03-23
JPS5285195A (en) 1977-07-15
SE7613673L (sv) 1977-06-13
DK553376A (de) 1977-06-13
CS188414B1 (en) 1979-03-30
FR2334360B1 (de) 1980-03-07
DK141874C (de) 1980-12-15
CA1069502A (en) 1980-01-08
ATA881776A (de) 1979-09-15
FI61189C (fi) 1982-06-10
CH622259A5 (de) 1981-03-31
AU2037776A (en) 1978-06-15
BE849318A (fr) 1977-04-01
FR2334360A1 (fr) 1977-07-08

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