DK1394272T3 - Fremgangsmåde til påvisning af ki-ras-mutationer - Google Patents

Fremgangsmåde til påvisning af ki-ras-mutationer

Info

Publication number
DK1394272T3
DK1394272T3 DK03020560T DK03020560T DK1394272T3 DK 1394272 T3 DK1394272 T3 DK 1394272T3 DK 03020560 T DK03020560 T DK 03020560T DK 03020560 T DK03020560 T DK 03020560T DK 1394272 T3 DK1394272 T3 DK 1394272T3
Authority
DK
Denmark
Prior art keywords
detecting
ras mutations
pcr
tissue
allele specific
Prior art date
Application number
DK03020560T
Other languages
Danish (da)
English (en)
Inventor
Arve Ulrik
Jan Jacob Koornstra
Dagfinn Ogreid
Original Assignee
Nordiag As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordiag As filed Critical Nordiag As
Application granted granted Critical
Publication of DK1394272T3 publication Critical patent/DK1394272T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Holo Graphy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Electrically Operated Instructional Devices (AREA)
  • Saccharide Compounds (AREA)
DK03020560T 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af ki-ras-mutationer DK1394272T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO954667A NO954667D0 (no) 1995-11-17 1995-11-17 Fremgangsmåte til deteksjon av Ki-ras mutasjoner
EP96939373A EP0868529B1 (en) 1995-11-17 1996-11-15 Method for detection of ki-ras mutations and kit to perform it

Publications (1)

Publication Number Publication Date
DK1394272T3 true DK1394272T3 (da) 2006-07-03

Family

ID=19898772

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96939373T DK0868529T3 (da) 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af Ki-ras-mutationer og et kit til udførelse deraf
DK03020560T DK1394272T3 (da) 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af ki-ras-mutationer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK96939373T DK0868529T3 (da) 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af Ki-ras-mutationer og et kit til udførelse deraf

Country Status (12)

Country Link
US (1) US6440661B1 (enExample)
EP (2) EP0868529B1 (enExample)
JP (1) JP2000500346A (enExample)
AT (2) ATE318934T1 (enExample)
AU (1) AU723980C (enExample)
DE (2) DE69635848T2 (enExample)
DK (2) DK0868529T3 (enExample)
ES (2) ES2262930T3 (enExample)
NO (2) NO954667D0 (enExample)
NZ (1) NZ322619A (enExample)
PT (2) PT868529E (enExample)
WO (1) WO1997019191A1 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9715034D0 (en) * 1997-07-18 1997-09-24 Zeneca Ltd Assay
JP4794052B2 (ja) * 1999-04-09 2011-10-12 ジェンザイム・コーポレーション 癌の指標である核酸を検出するための方法
US6531302B1 (en) * 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
US7368233B2 (en) * 1999-12-07 2008-05-06 Exact Sciences Corporation Methods of screening for lung neoplasm based on stool samples containing a nucleic acid marker indicative of a neoplasm
US6605451B1 (en) * 2000-06-06 2003-08-12 Xtrana, Inc. Methods and devices for multiplexing amplification reactions
EP2351853A1 (en) * 2000-06-06 2011-08-03 Life Technologies Corporation Method and devices for multiplexing amplification reactions
US7087414B2 (en) 2000-06-06 2006-08-08 Applera Corporation Methods and devices for multiplexing amplification reactions
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
EP1594975A4 (en) * 2002-12-04 2006-08-02 Applera Corp MULTIPLEX AMPLIFICATION OF POLYNUCLEOTIDES
WO2005113769A1 (en) * 2004-05-14 2005-12-01 Exact Sciences Corporation Method for stabilizing biological samples for nucleic acid analysis
US20070134709A1 (en) * 2005-12-14 2007-06-14 Xiping Xu Usages of MTHFR gene polymorphisms in predicting homocysteine level, disease risk, and treatment effects and related methods and kit
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
CN103424541B (zh) 2006-05-18 2018-01-30 分子压型学会股份有限公司 确定针对病状的个性化医疗介入的系统和方法
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
US8583380B2 (en) 2008-09-05 2013-11-12 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
CN107254538A (zh) 2008-11-12 2017-10-17 卡里斯生命科学瑞士控股有限责任公司 使用外来体来确定表现型的方法和系统
US20130005598A1 (en) * 2009-12-31 2013-01-03 The Regents Of The University Of Michigan Methods for Diagnosing The Malignant Potential of Pancreatic Cystic Lesions
KR20130056855A (ko) 2010-03-01 2013-05-30 카리스 라이프 사이언스 룩셈부르크 홀딩스 치료진단용 생물학적 지표들
KR20130043104A (ko) 2010-04-06 2013-04-29 카리스 라이프 사이언스 룩셈부르크 홀딩스 질병용 순환 생물학적 지표들
CN103228798B (zh) 2010-09-24 2015-12-09 斯坦福大学托管董事会 使用固定的引物直接捕获、扩增及测序靶标dna
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
CN102796811B (zh) * 2011-05-26 2013-12-18 上海赛安生物医药科技有限公司 检测kras突变的试剂及方法
AU2012273121B2 (en) 2011-06-19 2016-08-25 Abogen, Inc. Devices, solutions and methods for sample collection
US9637796B2 (en) * 2011-11-17 2017-05-02 The Johns Hopkins University Differential identification of pancreatic cysts
MX2015006757A (es) * 2012-11-30 2015-11-30 Applied Proteomics Inc Método para la evaluación de la presencia de o riesgo de tumores de colon.
SG11201607364RA (en) 2014-03-07 2016-10-28 Dna Genotek Inc Composition and method for stabilizing nucleic acids in biological samples
EP3281016A1 (en) 2015-04-10 2018-02-14 Applied Proteomics Inc. Protein biomarker panels for detecting colorectal cancer and advanced adenoma
US10753936B2 (en) 2016-07-22 2020-08-25 Van Andel Research Institute Method of detecting the level of a glycan
EP3810182A4 (en) 2018-06-19 2022-08-24 BioNTech US Inc. Neoantigens and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871838A (en) * 1985-07-23 1989-10-03 The Board Of Rijks Universiteit Leiden Probes and methods for detecting activated ras oncogenes
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and reagent for determining specific nucleotide variations
EP0672181B1 (en) 1992-04-01 2003-11-05 The Johns Hopkins University School Of Medicine Methods of detecting mammalian nucleic acids isolated from stool specimen and reagents therefor
ATE198358T1 (de) * 1992-04-27 2001-01-15 Dartmouth College Detektion von gensequenzen in biologischen flüssigkeiten
JPH06167492A (ja) * 1992-11-30 1994-06-14 Otsuka Pharmaceut Co Ltd 変異癌遺伝子の検出測定方法
DE19512369A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh Vorrichtung zur Isolierung von Nukleinsäuren

Also Published As

Publication number Publication date
NO982246D0 (no) 1998-05-15
AU7656996A (en) 1997-06-11
AU723980C (en) 2002-10-24
EP1394272B1 (en) 2006-03-01
PT1394272E (pt) 2006-07-31
WO1997019191A1 (en) 1997-05-29
DE69630234T2 (de) 2004-08-19
ES2262930T3 (es) 2006-12-01
JP2000500346A (ja) 2000-01-18
EP0868529B1 (en) 2003-10-01
NO324963B1 (no) 2008-01-14
DE69635848D1 (de) 2006-04-27
DE69630234D1 (de) 2003-11-06
ATE318934T1 (de) 2006-03-15
EP1394272A1 (en) 2004-03-03
ATE251222T1 (de) 2003-10-15
NZ322619A (en) 1999-04-29
PT868529E (pt) 2004-02-27
ES2208766T3 (es) 2004-06-16
DE69635848T2 (de) 2006-11-30
US6440661B1 (en) 2002-08-27
EP0868529A1 (en) 1998-10-07
AU723980B2 (en) 2000-09-07
DK0868529T3 (da) 2004-02-02
NO982246L (no) 1998-07-07
NO954667D0 (no) 1995-11-17

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