DK1394272T3 - Fremgangsmåde til påvisning af ki-ras-mutationer - Google Patents

Fremgangsmåde til påvisning af ki-ras-mutationer

Info

Publication number
DK1394272T3
DK1394272T3 DK03020560T DK03020560T DK1394272T3 DK 1394272 T3 DK1394272 T3 DK 1394272T3 DK 03020560 T DK03020560 T DK 03020560T DK 03020560 T DK03020560 T DK 03020560T DK 1394272 T3 DK1394272 T3 DK 1394272T3
Authority
DK
Denmark
Prior art keywords
detecting
ras mutations
pcr
tissue
allele specific
Prior art date
Application number
DK03020560T
Other languages
Danish (da)
English (en)
Inventor
Arve Ulrik
Jan Jacob Koornstra
Dagfinn Ogreid
Original Assignee
Nordiag As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordiag As filed Critical Nordiag As
Application granted granted Critical
Publication of DK1394272T3 publication Critical patent/DK1394272T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Saccharide Compounds (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Holo Graphy (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrically Operated Instructional Devices (AREA)
DK03020560T 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af ki-ras-mutationer DK1394272T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO954667A NO954667D0 (no) 1995-11-17 1995-11-17 Fremgangsmåte til deteksjon av Ki-ras mutasjoner
EP96939373A EP0868529B1 (en) 1995-11-17 1996-11-15 Method for detection of ki-ras mutations and kit to perform it

Publications (1)

Publication Number Publication Date
DK1394272T3 true DK1394272T3 (da) 2006-07-03

Family

ID=19898772

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03020560T DK1394272T3 (da) 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af ki-ras-mutationer
DK96939373T DK0868529T3 (da) 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af Ki-ras-mutationer og et kit til udførelse deraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK96939373T DK0868529T3 (da) 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af Ki-ras-mutationer og et kit til udførelse deraf

Country Status (12)

Country Link
US (1) US6440661B1 (enExample)
EP (2) EP1394272B1 (enExample)
JP (1) JP2000500346A (enExample)
AT (2) ATE318934T1 (enExample)
AU (1) AU723980C (enExample)
DE (2) DE69635848T2 (enExample)
DK (2) DK1394272T3 (enExample)
ES (2) ES2208766T3 (enExample)
NO (2) NO954667D0 (enExample)
NZ (1) NZ322619A (enExample)
PT (2) PT1394272E (enExample)
WO (1) WO1997019191A1 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9715034D0 (en) * 1997-07-18 1997-09-24 Zeneca Ltd Assay
AU767983B2 (en) * 1999-04-09 2003-11-27 Esoterix Genetic Laboratories, Llc Methods for detecting nucleic acids indicative of cancer
US6531302B1 (en) * 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
CA2394921A1 (en) 1999-12-07 2001-06-14 Anthony P. Shuber Supracolonic aerodigestive neoplasm detection
US7087414B2 (en) 2000-06-06 2006-08-08 Applera Corporation Methods and devices for multiplexing amplification reactions
US6605451B1 (en) * 2000-06-06 2003-08-12 Xtrana, Inc. Methods and devices for multiplexing amplification reactions
EP2351853A1 (en) * 2000-06-06 2011-08-03 Life Technologies Corporation Method and devices for multiplexing amplification reactions
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
EP2031070B1 (en) 2002-12-04 2013-07-17 Life Technologies Corporation Multiplex amplification of polynucleotides
WO2005113769A1 (en) * 2004-05-14 2005-12-01 Exact Sciences Corporation Method for stabilizing biological samples for nucleic acid analysis
US20070134709A1 (en) * 2005-12-14 2007-06-14 Xiping Xu Usages of MTHFR gene polymorphisms in predicting homocysteine level, disease risk, and treatment effects and related methods and kit
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
EP2032980A4 (en) 2006-05-18 2012-01-04 Molecular Profiling Inst Inc SYSTEM AND METHOD FOR DETERMINING INDIVIDUALIZED MEDICAL USE AGAINST A SICKNESS STATE
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
EP3216874A1 (en) 2008-09-05 2017-09-13 TOMA Biosciences, Inc. Methods for stratifying and annotating cancer drug treatment options
US7897356B2 (en) 2008-11-12 2011-03-01 Caris Life Sciences Methods and systems of using exosomes for determining phenotypes
WO2011082321A1 (en) * 2009-12-31 2011-07-07 Van Andel Research Institute Methods for diagnosing the malignant potential of pancreatic cystic lesions
AU2011223789A1 (en) 2010-03-01 2012-09-20 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
US9469876B2 (en) 2010-04-06 2016-10-18 Caris Life Sciences Switzerland Holdings Gmbh Circulating biomarkers for metastatic prostate cancer
KR20130113447A (ko) 2010-09-24 2013-10-15 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 고정된 프라이머들을 이용하여 표적 dna의 직접적인 캡쳐, 증폭 및 서열화
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
CN102796811B (zh) * 2011-05-26 2013-12-18 上海赛安生物医药科技有限公司 检测kras突变的试剂及方法
KR20140040239A (ko) 2011-06-19 2014-04-02 아보젠, 인크. 샘플 수집을 위한 장치, 용액 및 방법
JP5947392B2 (ja) * 2011-11-17 2016-07-06 ザ ジョンズ ホプキンス ユニバーシティー 膵嚢胞の鑑別
US20140234854A1 (en) * 2012-11-30 2014-08-21 Applied Proteomics, Inc. Method for evaluation of presence of or risk of colon tumors
ES2880310T3 (es) 2014-03-07 2021-11-24 Dna Genotek Inc Composición y método para estabilizar ácidos nucleicos en muestras biológicas
US9689874B2 (en) 2015-04-10 2017-06-27 Applied Proteomics, Inc. Protein biomarker panels for detecting colorectal cancer and advanced adenoma
US10753936B2 (en) 2016-07-22 2020-08-25 Van Andel Research Institute Method of detecting the level of a glycan
US12246067B2 (en) 2018-06-19 2025-03-11 Biontech Us Inc. Neoantigens and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871838A (en) * 1985-07-23 1989-10-03 The Board Of Rijks Universiteit Leiden Probes and methods for detecting activated ras oncogenes
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and reagent for determining specific nucleotide variations
WO1993020235A1 (en) 1992-04-01 1993-10-14 The Johns Hopkins University School Of Medicine Methods of detecting mammalian nucleic acids isolated from stool specimen and reagents therefor
CA2134552A1 (en) 1992-04-27 1993-11-11 George D. Sorenson Detection of gene sequences in biological fluids
JPH06167492A (ja) * 1992-11-30 1994-06-14 Otsuka Pharmaceut Co Ltd 変異癌遺伝子の検出測定方法
DE19512369A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh Vorrichtung zur Isolierung von Nukleinsäuren

Also Published As

Publication number Publication date
ATE318934T1 (de) 2006-03-15
DE69635848T2 (de) 2006-11-30
EP1394272A1 (en) 2004-03-03
DE69630234T2 (de) 2004-08-19
ES2262930T3 (es) 2006-12-01
NZ322619A (en) 1999-04-29
PT868529E (pt) 2004-02-27
DE69635848D1 (de) 2006-04-27
PT1394272E (pt) 2006-07-31
DE69630234D1 (de) 2003-11-06
ES2208766T3 (es) 2004-06-16
DK0868529T3 (da) 2004-02-02
US6440661B1 (en) 2002-08-27
NO324963B1 (no) 2008-01-14
JP2000500346A (ja) 2000-01-18
AU723980C (en) 2002-10-24
AU7656996A (en) 1997-06-11
WO1997019191A1 (en) 1997-05-29
NO954667D0 (no) 1995-11-17
EP0868529A1 (en) 1998-10-07
NO982246L (no) 1998-07-07
AU723980B2 (en) 2000-09-07
NO982246D0 (no) 1998-05-15
EP1394272B1 (en) 2006-03-01
EP0868529B1 (en) 2003-10-01
ATE251222T1 (de) 2003-10-15

Similar Documents

Publication Publication Date Title
DK1394272T3 (da) Fremgangsmåde til påvisning af ki-ras-mutationer
DE60238493D1 (de) Is von seltenen zellen verwendete markierte zellen
ATE191513T1 (de) Verfahren zur amplifikation von nukleinsäuren
DK0518650T3 (da) Sekvensspecifik DNA-binding med p53
EP0668777A4 (en) PROSTATE SPECIFIC MEMBRANE ANTIGEN.
EP0961833A4 (en) HYALURONIDASE FROM HUMAN PLASMA
EP0357611A4 (en) A method of detection of carcinogenic human papillomavirus
EP1026262A3 (en) Oligonucleotide primers for efficient detection of hepatitis C virus (HCV) and methods of use thereof
AU2002303444A1 (en) Detection of microsatellite instability and its use in diagnosis of tumors
AU2003226052A1 (en) Methods for detecting abnormally methylated nucleic acid in heterogeneous biological samples
DE69120936D1 (de) Genetischer test für zytochrom-p450
DE68925727D1 (de) Methode zur Bestimmung der optimalen Arbeitsbedingungen in einem elektrochemischen Detektor und elektrochemischer Detektor, diese Methode benutzend
DE69019886D1 (de) Katheter und Instrumentarium zur extrakorporalen Zirkulation.
ES2155428T3 (es) Procedimiento de regulacion de la aireacion durante el tratamiento biologico de aguas residuales.
ATE360092T1 (de) Nukleinsäureprimer und -sonden zur detektion onkogener humaner papillomaviren
DK0477972T3 (enExample)
DK1228241T3 (da) Genetisk test til at bestemme non-responsevne på statinlægemiddelbehandling
DE3884695D1 (de) Träger für gegossene Teile und Methode zur Verwendung des Trägers.
ATE56990T1 (de) Verfahren und reagenz zur bestimmung von gesamt- bilirubin.
DE59006412D1 (de) Vorrichtung zur Bestimmung der biochemischen Sauerstoffverbrauchsrate und deren Verwendung.
AU2283792A (en) Direct detection of hepatitis c virus rna
DE69531505D1 (de) Verfahren zur zellerkennung
IT1282626B1 (it) Processo di preparazione di perfluoropolieteri perossidici
ATE355301T1 (de) Moraxella catharralis proteine
DK1313850T3 (da) Nucleinsyre og tilsvarende protein med navnet 85PB3 anvendelige til behandling og påvisning af cancer