DK1372551T3 - Faciale amphifile polymerer som anti-infektionsmidler - Google Patents

Faciale amphifile polymerer som anti-infektionsmidler

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Publication number
DK1372551T3
DK1372551T3 DK02761083T DK02761083T DK1372551T3 DK 1372551 T3 DK1372551 T3 DK 1372551T3 DK 02761083 T DK02761083 T DK 02761083T DK 02761083 T DK02761083 T DK 02761083T DK 1372551 T3 DK1372551 T3 DK 1372551T3
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DK
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Prior art keywords
polymers
amphiphilic polymers
infective agents
disclosed
facial
Prior art date
Application number
DK02761083T
Other languages
Danish (da)
English (en)
Inventor
W F Degrado
Gregory N Tew
M L Klein
Dahui Liu
Jing Yuan
Original Assignee
Univ Pennsylvania
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Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
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Publication of DK1372551T3 publication Critical patent/DK1372551T3/da

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    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
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    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/40—Polyesters derived from ester-forming derivatives of polycarboxylic acids or of polyhydroxy compounds, other than from esters thereof
    • C08G63/44—Polyamides; Polynitriles
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Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4170214B2 (ja) * 2001-03-08 2008-10-22 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア 抗感染用剤としての表面両親媒性ポリマー
EP1535235A1 (en) * 2002-05-28 2005-06-01 The Trustees of The University of Pennsylvania Methods, systems, and computer program products for computational analysis and design of amphiphilic polymers
GB0212667D0 (en) * 2002-05-31 2002-07-10 Psimedica Ltd Orthopaedic scaffolds for tissue engineering
AU2003301284A1 (en) * 2002-10-18 2004-05-04 Ciba Specialty Chemicals Holding Inc. The use of biomimic polymers in personal care compositions
EP1567559A4 (en) * 2002-11-12 2008-04-16 Polymer Technology Group Inc REGULATION OF MOLECULAR POLYMER SURFACE ARCHITECTURE USING AMPHIPATHIC TERMINAL GROUPS
CN102432511B (zh) 2003-03-17 2016-06-08 宾夕法尼亚州大学理事会 表面两亲聚合物和低聚物及其应用
AU2013263761B2 (en) * 2003-03-17 2016-06-09 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers and oligomers and uses thereof
ATE356515T1 (de) * 2003-09-03 2007-03-15 Research In Motion Ltd Verfahren und vorrichtungen zur anzeige eines heimnetzwerknamens
TW201509411A (zh) * 2004-01-20 2015-03-16 Univ Pennsylvania 面部兩性聚合物和寡聚物及其用途
KR20120107142A (ko) * 2004-01-23 2012-09-28 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 표면적으로 친양쪽성인 폴리아릴 및 폴리아릴알키닐 중합체와 올리고머, 그리고 이들의 용도
US8067073B2 (en) * 2004-03-25 2011-11-29 Boston Scientific Scimed, Inc. Thermoplastic medical device
ES2433663T3 (es) 2004-06-15 2013-12-12 Polymedix, Inc. Compuestos policatiónicos y usos de los mismos
EP2325218A1 (en) 2004-07-23 2011-05-25 The Trustees Of The University Of Pennsylvania Antimicrobial copolymers and uses thereof
EP1793838A2 (en) 2004-08-18 2007-06-13 Polymedix, Inc. Amphiphilic polynorbornene derivatives and methods of using the same
US20070055013A1 (en) * 2005-02-21 2007-03-08 Noriho Kamiya Substrate and method of immobilizing protein
EP2298074A3 (en) 2005-02-25 2011-10-26 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer
US8349991B2 (en) * 2005-04-19 2013-01-08 Massachusetts Institute Of Technology Amphiphilic polymers and methods of use thereof
US20070036743A1 (en) * 2005-08-10 2007-02-15 Isp Investments Inc. Antimicrobial polymers
US20070048249A1 (en) 2005-08-24 2007-03-01 Purdue Research Foundation Hydrophilized bactericidal polymers
US8343473B2 (en) 2005-08-24 2013-01-01 Purdue Research Foundation Hydrophilized antimicrobial polymers
US20070172434A1 (en) * 2006-01-24 2007-07-26 Jernberg Gary R Antimicrobial dental materials, restorations, and prostheses
US8778376B2 (en) * 2006-06-09 2014-07-15 Advanced Cardiovascular Systems, Inc. Copolymer comprising elastin pentapeptide block and hydrophilic block, and medical device and method of treating
FR2908414B1 (fr) 2006-11-13 2012-01-20 Centre Nat Rech Scient Immobilisation de proteines membranaires sur un support par l'intermediaire d'une molecule amphiphile
US20090092574A1 (en) * 2006-12-29 2009-04-09 Scott Richard W Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
US8119764B2 (en) 2007-09-11 2012-02-21 Solvay Advanced Polymers, L.L.C. Medical devices made of a polymer material
US7923486B2 (en) * 2007-10-04 2011-04-12 Board Of Regents, The University Of Texas System Bio-polymer and scaffold-sheet method for tissue engineering
US8742064B2 (en) * 2007-10-23 2014-06-03 Solvay Advanced Polymers, L.L.C. Medical tubings made of a polymer material
TWI478915B (zh) 2008-10-27 2015-04-01 Cellceutix Corp 宿主防禦之合成模擬物及其用途
CN102612508A (zh) 2009-10-22 2012-07-25 波利梅伊公司 用于制备聚合化合物的方法
EP2316498A1 (en) * 2009-10-30 2011-05-04 Unomedical A/S A medical hollow tube article
RU2012133562A (ru) * 2010-01-07 2014-02-20 Полимедикс Инк. Антигепариновые соединения
US8790379B2 (en) 2010-06-23 2014-07-29 Zimmer, Inc. Flexible plate fixation of bone fractures
WO2011163387A2 (en) 2010-06-23 2011-12-29 Apex Biomedical Company, Llc Flexible plate fixation of bone fractures
WO2012158672A2 (en) 2011-05-16 2012-11-22 Polymedix, Inc. Compounds for use in treatment of mucositis
TWI487543B (zh) 2011-12-12 2015-06-11 Ind Tech Res Inst 梳狀結構高分子、醫療裝置的改質方法及醫療裝置
SG11201403215TA (en) 2011-12-13 2014-09-26 Cellceutix Corp Cyclic compounds and methods of making and using the same
US9295508B2 (en) 2012-02-03 2016-03-29 Zimmer, Inc. Bone plate for elastic osteosynthesis
WO2013130738A1 (en) * 2012-02-29 2013-09-06 Polymedix, Inc. Compounds and methods for treating malaria
JP2013241551A (ja) * 2012-05-23 2013-12-05 National Institute Of Advanced Industrial Science & Technology 基体表面を有機分子で修飾することにより、菌体を除去できる表面処理剤及び該有機分子による表面処理方法並びに抗菌処理した基体
EP3346840A4 (en) * 2015-09-08 2019-03-13 Nanyang Technological University PROCESS FOR INHIBITING QUORUM DETECTION IN PSEUDOMONAS AERUGINOSA
JP6294443B2 (ja) * 2016-12-06 2018-03-14 国立研究開発法人産業技術総合研究所 基体表面を有機分子で修飾することにより、菌体を除去できる表面処理剤及び該有機分子による表面処理方法並びに抗菌処理した基体
US20180340046A1 (en) 2017-05-27 2018-11-29 Poly Group LLC Dispersible antimicrobial complex and coatings therefrom
US20180362678A1 (en) 2017-06-16 2018-12-20 Poly Group LLC Polymeric antimicrobial surfactant
GB201711555D0 (en) * 2017-07-18 2017-08-30 Kent Innovation & Entpr Antibacterial compounds
EP3691775A1 (en) 2017-10-05 2020-08-12 Fresenius Medical Care Holdings, Inc. Polysulfone-urethane copolymer, membranes and products incorporating same, and methods for making and using same
US11324538B2 (en) 2019-12-04 2022-05-10 Biomet Manufacturing, Llc Active bone plate
WO2021248008A1 (en) 2020-06-05 2021-12-09 Innovation Pharmaceuticals Inc. Arylamide compounds for treatment and prevention of viral infections

Family Cites Families (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH525898A (de) 1961-09-11 1972-07-31 Wander Ag Dr A Verfahren zur Herstellung mehrbasischer Verbindungen
CH479557A (de) 1961-09-11 1969-10-15 Wander Ag Dr A Verfahren zur Herstellung neuer mehrbasischer Verbindungen
GB1033776A (en) * 1963-06-06 1966-06-22 Sterling Drug Inc Iodinated acid amides and esters and salts thereof
CH475331A (de) * 1965-07-05 1969-07-15 Ciba Geigy Verfahren zum Härten von Gelatine
US3484407A (en) * 1967-01-13 1969-12-16 Monsanto Co Linear condensation polymers containing carbonamide and heterocyclic linkages
GB1324087A (en) 1969-07-18 1973-07-18 Commw Scient Ind Res Org Copolymers and veterinary compositions treated therewith
US4118232A (en) * 1971-04-07 1978-10-03 Ciba-Geigy Ag Photographic material containing sulphonic acid group containing disazo dyestuffs
US3829563A (en) * 1972-11-30 1974-08-13 Hoffmann La Roche Emollient cleansing compositions
US4038416A (en) 1975-09-11 1977-07-26 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition and method of the use thereof
JPS5285133A (en) 1976-01-05 1977-07-15 Chugai Pharmaceut Co Ltd Bis-(benzamide)-benzene derivatives
DE2616479C2 (de) 1976-04-14 1986-12-04 Brickl, Rolf, Dr., 7951 Warthausen Substituierte Fluoracylresorcine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel und Kosmetika
US4392848A (en) * 1979-06-25 1983-07-12 The Procter & Gamble Company Catheterization
US4343788A (en) * 1979-06-29 1982-08-10 The Procter & Gamble Company Antimicrobial polymer compositions
US4252951A (en) * 1979-10-09 1981-02-24 Eli Lilly And Company Isolation of syn-7-(2-amino-4-thiazolyl)-(methoxyimino)acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid
JPS5928521B2 (ja) 1980-03-04 1984-07-13 兼商株式会社 殺線虫組成物
FR2527618A1 (fr) * 1982-05-25 1983-12-02 Thomson Csf Polymeres contenant des heterocycles et des noyaux aromatiques et materiaux organiques conducteurs formes a partir de ces polymeres
US4515910A (en) * 1983-01-26 1985-05-07 Rawls Henry R Interpolymeric resin for treatment of teeth
JPS59177558U (ja) 1983-05-14 1984-11-27 ヤンマーディーゼル株式会社 農用トラクタ−のパワ−ステアリング装置
DE3533612A1 (de) 1985-09-20 1987-04-02 Johannes Reinmueller Neuartige verwendung von taurolin
CA1290490C (en) 1985-11-20 1991-10-08 Masakazu Uekita Amphiphilic high polymer and process for producing the same
JPS6322067A (ja) * 1986-03-10 1988-01-29 Nippon Soda Co Ltd ピロ−ル誘導体のｌｂ膜およびその製造方法
JPS62224090A (ja) 1986-03-26 1987-10-02 Polyplastics Co 高分子圧電材料
JPH0739457B2 (ja) * 1986-05-14 1995-05-01 タキロン株式会社 両親媒性セグメントポリウレタン
US4826829A (en) * 1986-07-23 1989-05-02 Fmc Corporation 2-Substituted ethynyl thiophene pesticides
US4847353A (en) * 1986-11-20 1989-07-11 Nippon Steel Chemical Co., Ltd. Resins of low thermal expansivity
US6083602A (en) * 1988-03-14 2000-07-04 Nextec Applications, Inc. Incontinent garments
US5912116A (en) * 1988-03-14 1999-06-15 Nextec Applications, Inc. Methods of measuring analytes with barrier webs
US5856245A (en) * 1988-03-14 1999-01-05 Nextec Applications, Inc. Articles of barrier webs
US6040251A (en) * 1988-03-14 2000-03-21 Nextec Applications Inc. Garments of barrier webs
US5874164A (en) * 1988-03-14 1999-02-23 Nextec Applications, Inc. Barrier webs having bioactive surfaces
JPH0229436A (ja) * 1988-07-19 1990-01-31 Ricoh Co Ltd 導電性ピロール類重合膜の光化学的製造方法
JP2597160B2 (ja) * 1988-09-02 1997-04-02 富士写真フイルム株式会社 電子写真感光体
US4943624A (en) * 1988-10-28 1990-07-24 Lehigh University Supramolecular surfactants: amphiphilic polymers designed to disrupt lipid membranes
US5071648A (en) * 1989-04-06 1991-12-10 Merocel Corporation Polymeric broad-spectrum antimicrobial materials
US5073564A (en) * 1990-07-06 1991-12-17 Fmc Corporation Ethynylbenzothiophene pesticides
US5219965A (en) * 1990-11-27 1993-06-15 Bausch & Lomb Incorporated Surface modification of polymer objects
EP0489660B1 (fr) 1990-12-06 1994-11-02 Roussel-Uclaf Utilisation de thiazolylalkoxy acrylates pour la fabrication de compositions insecticides et/ou acaricides
US5648070A (en) * 1991-12-04 1997-07-15 Cobe Laboratories, Inc. Biocompatible anion exchange materials
US5424063A (en) 1992-01-09 1995-06-13 The Dow Chemical Company Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process
US5262476A (en) * 1992-03-10 1993-11-16 The Dow Chemical Company Polycarbonate/polyester blends modified with poly(phenylene ether)
DE19709075A1 (de) * 1997-03-06 1998-09-10 Huels Chemische Werke Ag Verfahren zur Herstellung antimikrobieller Kunststoffe
US5847047A (en) * 1993-06-22 1998-12-08 E. I. Du Pont De Nemours And Company Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type
WO1995002617A1 (fr) * 1993-07-14 1995-01-26 Nippon Chemical Industrial Co., Ltd. Polymere antimicrobien, lentille de contact et produits d'entretien de lentilles de contact
WO1995019974A2 (en) 1994-01-24 1995-07-27 Harris Stephen J Calixarene-based compounds having antibacterial, antifungal, anticancer-hiv activity
ATE198119T1 (de) 1994-09-01 2001-01-15 Novo Nordisk As Eine grundlegende proteinzusammensetzung zur abtötung oder inhibierung mikrobieller zellen
GB9419206D0 (en) 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
JP2000507997A (ja) * 1996-02-09 2000-06-27 サーフェス ソルーションズ ラボラトリーズ インコーポレイテッド 水性の親水性被覆組成物及びそれから製造した物品
US6034129A (en) 1996-06-24 2000-03-07 Geltex Pharmaceuticals, Inc. Ionic polymers as anti-infective agents
FR2753094B1 (fr) 1996-09-06 1998-10-16 Oreal Composition de teinture d'oxydation pour fibres keratiniques comprenant un polymere amphiphile anionique
US5962521A (en) * 1997-04-04 1999-10-05 Guilford Pharmaceuticals Inc. Hydroxamic acid derivatives
AU4722197A (en) 1996-10-22 1998-05-15 Daiichi Pharmaceutical Co., Ltd. Novel remedies for infectious diseases
US6107397A (en) * 1997-03-24 2000-08-22 Basf Aktiengesellschaft Aqueous copolymer dispersions of water-soluble monomers with N-vinyl groups and hydrophobic monomers
US6217886B1 (en) 1997-07-14 2001-04-17 The Board Of Trustees Of The University Of Illinois Materials and methods for making improved micelle compositions
DE19735715A1 (de) * 1997-08-18 1999-02-25 Huels Chemische Werke Ag Amphiphile Polymere auf Basis von Polyestern mit einkondensierten acetalischen Gruppen, die bei Raumtemperatur flüssig sind, sowie ihr Einsatz in Wasch- und Reinigungsmitteln
US5994340A (en) * 1997-08-29 1999-11-30 Synphar Laboratories, Inc. Azetidinone derivatives as β-lactamase inhibitors
JPH11152329A (ja) 1997-11-21 1999-06-08 Hitachi Chem Co Ltd ポリアミド又はその誘導体の製造法
GB2333454B (en) 1998-03-26 2000-08-09 Us Army Substituted aromatic compounds for treatment of antibiotic resistant infections
CA2234410C (en) * 1998-05-01 2002-07-16 Jih Ru Hwu Novel phloroglucide derivatives and their pharmaceutical use
US6399629B1 (en) * 1998-06-01 2002-06-04 Microcide Pharmaceuticals, Inc. Efflux pump inhibitors
US6686345B2 (en) * 1998-07-16 2004-02-03 Research Development Foundation DNA-cleaving antitumor agents
DE19845358A1 (de) * 1998-10-02 2000-04-06 Roehm Gmbh Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe
AR024237A1 (es) 1998-12-21 2002-09-25 Novartis Ag Copolimeros en bloque anfifilicos, procedimiento y precursores para su preparacion, y articulo moldeado obtenible a partir de los mismos
ES2223464T3 (es) * 1999-02-01 2005-03-01 Eisai Co., Ltd. Compuestos adyuvantes inmunologicos.
US6166172A (en) * 1999-02-10 2000-12-26 Carnegie Mellon University Method of forming poly-(3-substituted) thiophenes
DE19908184A1 (de) * 1999-02-25 2000-08-31 Basf Ag Verfahren zur Herstellung wässriger Dispersionen von Copolymerisaten aus hydrophilen und hydrophoben Monomeren sowie daraus erhältliche Copolymerisate und deren Anwendungen
DE19921902A1 (de) 1999-05-12 2000-11-16 Creavis Tech & Innovation Gmbh Mikrobizide Copolymere
US6309633B1 (en) 1999-06-19 2001-10-30 Nobex Corporation Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same
JP2001133975A (ja) 1999-08-23 2001-05-18 Toray Ind Inc ポジ型感光性樹脂前駆体組成物
AU2001239725A1 (en) 2000-01-13 2001-07-24 Tularik, Inc. Antibacterial agents
PL357010A1 (en) 2000-01-28 2004-07-12 Novo Nordisk A/S Propionic acid derivatives and their use in the treatment of diabetes and obesity
US6768009B1 (en) 2000-03-24 2004-07-27 The Regents Of The University Of California N-halamine vinyl compounds and their polymeric biocides
JP4170214B2 (ja) * 2001-03-08 2008-10-22 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア 抗感染用剤としての表面両親媒性ポリマー
AU2002316148A1 (en) 2001-05-21 2002-12-03 Molecular Electronics Corporation Lipase catalyzed esterification, transesterification, and hydrolysis of arylthiols and aryl-thioesters
JP2002363261A (ja) 2001-06-06 2002-12-18 Sumitomo Bakelite Co Ltd 難燃性エポキシ樹脂組成物、半導体封止材料及び半導体装置
CN1170816C (zh) 2001-07-19 2004-10-13 温州师范学院 N、n'－二取代苯胺基芳香二甲酰胺及其衍生物、制备方法和用途
AU2002319677B8 (en) 2001-07-23 2009-04-30 Atwater Management Llc Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods
JP2003165805A (ja) 2001-11-28 2003-06-10 Mitsubishi Rayon Co Ltd 両親媒性重合体の製造方法
US20030130454A1 (en) * 2001-11-07 2003-07-10 Mitsubishi Rayon Co., Ltd. Process for producing amphipathic polymers
EP1535235A1 (en) * 2002-05-28 2005-06-01 The Trustees of The University of Pennsylvania Methods, systems, and computer program products for computational analysis and design of amphiphilic polymers
JP2005529604A (ja) * 2002-06-13 2005-10-06 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア 粗粒度モデルを用いる生体膜をシミュレートするための方法、システム、およびコンピュータプログラム製品
WO2004014903A1 (en) 2002-08-02 2004-02-19 Ab Science 2-(3-aminoaryl)amino-4-aryl-thiazoles and their use as c-kit inhibitors
US7378479B2 (en) * 2002-09-13 2008-05-27 Lubrizol Advanced Materials, Inc. Multi-purpose polymers, methods and compositions
US7141519B2 (en) 2002-09-20 2006-11-28 Kimberly-Clark Worldwide, Inc. Ion triggerable, cationic polymers, a method of making same and items using same
JP3836420B2 (ja) 2002-11-18 2006-10-25 孝志 澤口 両親媒性メタクリレート及びその重合体
CN102432511B (zh) * 2003-03-17 2016-06-08 宾夕法尼亚州大学理事会 表面两亲聚合物和低聚物及其应用
JP2004323688A (ja) 2003-04-25 2004-11-18 Mitsubishi Rayon Co Ltd 両親媒性重合体およびその製造方法
US7332623B2 (en) * 2003-06-30 2008-02-19 Kaohsiung Medical University Aryl-substituted acyclic enediyne compounds
US20050004211A1 (en) 2003-06-30 2005-01-06 Kaohsiung Medical University Pharmaceutical compositions comprising aryl-substituted acyclic enediyne compounds
US7781498B2 (en) * 2003-07-03 2010-08-24 Mallard Creek Polymers, Inc. Cationic latex as a carrier for bioactive ingredients and methods for making and using the same
US6953974B2 (en) * 2003-08-26 2005-10-11 Texas Instruments Incorporated EEPROM device and method for providing lower programming voltage
ITMI20031790A1 (it) * 2003-09-19 2005-03-20 Consiglio Nazionale Ricerche Antagonistici abiotici dell'eparina.
US20070173752A1 (en) * 2003-11-28 2007-07-26 Troels Schonfeldt Integrated package
KR20120107142A (ko) 2004-01-23 2012-09-28 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 표면적으로 친양쪽성인 폴리아릴 및 폴리아릴알키닐 중합체와 올리고머, 그리고 이들의 용도
ES2433663T3 (es) * 2004-06-15 2013-12-12 Polymedix, Inc. Compuestos policatiónicos y usos de los mismos
EP2325218A1 (en) 2004-07-23 2011-05-25 The Trustees Of The University Of Pennsylvania Antimicrobial copolymers and uses thereof
ES2378999T3 (es) 2004-10-04 2012-04-19 Regents Of The University Of Minnesota Miméticos con conformación peptídica a base de calixareno, métodos de uso, y métodos para obtenerlos
EP2298074A3 (en) 2005-02-25 2011-10-26 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer

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EP1372551A2 (en) 2004-01-02
ES2314087T3 (es) 2009-03-16
KR100904284B1 (ko) 2009-06-25
WO2002100295A2 (en) 2002-12-19
KR100902171B1 (ko) 2009-06-10
US7173102B2 (en) 2007-02-06
DK1372674T3 (da) 2011-09-12
JP4170214B2 (ja) 2008-10-22
AU2002254133B2 (en) 2006-12-21
JP2009155653A (ja) 2009-07-16
WO2002072007A3 (en) 2003-05-22
US8889163B2 (en) 2014-11-18
EP1372674A2 (en) 2004-01-02
CA2452977C (en) 2013-07-16
KR20040011472A (ko) 2004-02-05
CN102295744A (zh) 2011-12-28
WO2002072007A2 (en) 2002-09-19
JP2005507953A (ja) 2005-03-24
EP2289524A1 (en) 2011-03-02
CA2789997A1 (en) 2002-12-19
JP2005502736A (ja) 2005-01-27
CN100506870C (zh) 2009-07-01
EP1372674B1 (en) 2011-05-25
EP1372551B1 (en) 2008-09-17
KR20040011471A (ko) 2004-02-05
EP1372674A4 (en) 2004-05-12
ATE510547T1 (de) 2011-06-15
WO2002100295A3 (en) 2003-05-01
US20040202639A1 (en) 2004-10-14
CN1505646A (zh) 2004-06-16
EP1372551A4 (en) 2004-05-12
US20040185257A1 (en) 2004-09-23
AU2002326375B2 (en) 2006-12-21
DE60228941D1 (en) 2008-10-30
CN1522148A (zh) 2004-08-18
CA2452977A1 (en) 2002-09-19
CA2451117A1 (en) 2002-12-19
ATE408387T1 (de) 2008-10-15
CN102295744B (zh) 2014-07-02

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