DK136981B - Analogifremgangsmåde til fremstilling af basisk substituerede benzylphthalazon-derivater. - Google Patents

Analogifremgangsmåde til fremstilling af basisk substituerede benzylphthalazon-derivater.

Info

Publication number
DK136981B
DK136981B DK30272AA DK30272A DK136981B DK 136981 B DK136981 B DK 136981B DK 30272A A DK30272A A DK 30272AA DK 30272 A DK30272 A DK 30272A DK 136981 B DK136981 B DK 136981B
Authority
DK
Denmark
Prior art keywords
benzylphthalazone
derivatives
preparation
analogous process
basic substituted
Prior art date
Application number
DK30272AA
Other languages
Danish (da)
English (en)
Other versions
DK136981C (enrdf_load_stackoverflow
Inventor
Dietrich Vogelsang
Gerhard Scheffler
Norbert Brock
Dieter Lenke
Original Assignee
Asta Werke Ag Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab
Publication of DK136981B publication Critical patent/DK136981B/da
Application granted granted Critical
Publication of DK136981C publication Critical patent/DK136981C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK30272AA 1971-01-22 1972-01-21 Analogifremgangsmåde til fremstilling af basisk substituerede benzylphthalazon-derivater. DK136981B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH101271A CH572914A5 (enrdf_load_stackoverflow) 1971-01-22 1971-01-22

Publications (2)

Publication Number Publication Date
DK136981B true DK136981B (da) 1977-12-27
DK136981C DK136981C (enrdf_load_stackoverflow) 1978-06-05

Family

ID=4200381

Family Applications (1)

Application Number Title Priority Date Filing Date
DK30272AA DK136981B (da) 1971-01-22 1972-01-21 Analogifremgangsmåde til fremstilling af basisk substituerede benzylphthalazon-derivater.

Country Status (21)

Country Link
AR (1) AR197293A1 (enrdf_load_stackoverflow)
AT (1) AT313288B (enrdf_load_stackoverflow)
AU (1) AU3767472A (enrdf_load_stackoverflow)
BE (1) BE778269A (enrdf_load_stackoverflow)
CA (1) CA1010041A (enrdf_load_stackoverflow)
CH (1) CH572914A5 (enrdf_load_stackoverflow)
DE (1) DE2164058C3 (enrdf_load_stackoverflow)
DK (1) DK136981B (enrdf_load_stackoverflow)
ES (1) ES398949A1 (enrdf_load_stackoverflow)
FI (1) FI53704C (enrdf_load_stackoverflow)
FR (1) FR2122517B1 (enrdf_load_stackoverflow)
GB (1) GB1377231A (enrdf_load_stackoverflow)
HK (1) HK62577A (enrdf_load_stackoverflow)
HU (1) HU163979B (enrdf_load_stackoverflow)
IL (1) IL38496A (enrdf_load_stackoverflow)
NL (1) NL177116C (enrdf_load_stackoverflow)
OA (1) OA04087A (enrdf_load_stackoverflow)
PL (1) PL88930B1 (enrdf_load_stackoverflow)
SE (1) SE404604B (enrdf_load_stackoverflow)
YU (1) YU35361B (enrdf_load_stackoverflow)
ZA (1) ZA718712B (enrdf_load_stackoverflow)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE49205T1 (de) * 1984-09-14 1990-01-15 Asta Pharma Ag Substituierte benzylphthalazinon-derivate.
DE3836579A1 (de) * 1987-11-13 1989-05-24 Asta Pharma Ag Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge
ATE106883T1 (de) * 1987-11-13 1994-06-15 Asta Medica Ag Azelastin-embonat, verfahren zu seiner herstellung und pharmazeutische zubereitungen, die als wirkstoff azelastin-embonat enthalten.
PT88984B (pt) * 1987-11-13 1993-01-29 Asta Medica Ag Processo para a preparação de embonato de azelastina e de composições earmacâutxcas que 0 contêm como ingrediente activo
DE3877904D1 (de) * 1987-11-13 1993-03-11 Asta Pharma Ag Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge.
DE3912292A1 (de) * 1988-04-20 1989-11-09 Asta Pharma Ag Azelastin enthaltende arzneimittel mit kontrollierter wirkstoffabgabe
US5110814A (en) * 1989-01-11 1992-05-05 Asta Pharma Ag Azelastine and its salts used to combat psoriasis
EP0396069B1 (de) * 1989-05-05 1994-06-22 ASTA Medica Aktiengesellschaft Salze des Azelastins mit verbesserter Löslichkeit
DE4207234A1 (de) * 1992-03-07 1993-09-09 Asta Medica Ag Neue aminocarbonsaeure-derivate mit antiallergischer/antiasthmatischer wirkung und verfahren zu deren herstellung
DE4345224C2 (de) * 1993-12-18 1999-07-01 Asta Medica Ag Verfahren zur Herstellung von Säureadditionssalzen des Azelastins und Flezelastins
DE4343409C2 (de) * 1993-12-18 1997-03-20 Asta Medica Ag Verbessertes Verfahren zur Herstellung von Hexahydroazepinonen und Hexahydroazepinolen
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
PL2486942T3 (pl) 2004-11-24 2019-05-31 Meda Pharmaceuticals Inc Kompozycje zawierające azelastynę oraz sposoby ich stosowania
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
CA2649029A1 (en) * 2006-04-20 2007-11-01 Glaxo Group Limited 2-substituted 4-benzylphthalazinone derivatives as histamine h1 and h3 antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1046625B (de) * 1957-08-15 1958-12-18 Hydrierwerk Rodleben Veb Verfahren zur Herstellung basisch substituierter Phthalazone
GB1100911A (en) * 1963-08-20 1968-01-24 Benger Lab Ltd Phthalazine derivatives
DK119061B (da) * 1966-10-28 1970-11-09 Hydrierwerk Rodleben Veb Fremgangsmåde til fremstilling af basisk substituerede phthalazoner eller salte eller kvaternære ammoniumforbindelser deraf.

Also Published As

Publication number Publication date
CH572914A5 (enrdf_load_stackoverflow) 1976-02-27
FR2122517A1 (enrdf_load_stackoverflow) 1972-09-01
CA1010041A (en) 1977-05-10
GB1377231A (en) 1974-12-11
SU440838A3 (enrdf_load_stackoverflow) 1974-08-25
OA04087A (fr) 1979-10-30
NL177116B (nl) 1985-03-01
AT313288B (de) 1974-02-11
HK62577A (en) 1977-12-30
PL88930B1 (enrdf_load_stackoverflow) 1976-10-30
FI53704B (enrdf_load_stackoverflow) 1978-03-31
FR2122517B1 (enrdf_load_stackoverflow) 1975-08-01
DE2164058B2 (de) 1980-10-23
IL38496A (en) 1975-05-22
YU35361B (en) 1980-12-31
SE404604B (sv) 1978-10-16
ZA718712B (en) 1972-09-27
NL7200400A (enrdf_load_stackoverflow) 1972-07-25
AU3767472A (en) 1973-07-12
IL38496A0 (en) 1972-03-28
DE2164058A1 (de) 1972-07-27
DK136981C (enrdf_load_stackoverflow) 1978-06-05
YU11272A (en) 1980-06-30
FI53704C (fi) 1978-07-10
HU163979B (enrdf_load_stackoverflow) 1973-12-28
AR197293A1 (es) 1974-03-29
BE778269A (fr) 1972-07-19
NL177116C (nl) 1985-08-01
DE2164058C3 (de) 1981-08-13
ES398949A1 (es) 1975-06-01

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