DK136528B - Analogifremgangsmåde til fremstilling af aromatiske ethere eller disse forbindelsers syreadditionssalte eller de tilsvarende optisk aktive antipoder. - Google Patents
Analogifremgangsmåde til fremstilling af aromatiske ethere eller disse forbindelsers syreadditionssalte eller de tilsvarende optisk aktive antipoder.Info
- Publication number
- DK136528B DK136528B DK680869AA DK680869A DK136528B DK 136528 B DK136528 B DK 136528B DK 680869A A DK680869A A DK 680869AA DK 680869 A DK680869 A DK 680869A DK 136528 B DK136528 B DK 136528B
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- preparation
- acid addition
- addition salts
- optically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
- C07D203/10—Radicals substituted by singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1926968A CH528516A (de) | 1968-12-24 | 1968-12-24 | Verfahren zur Herstellung von aromatischen Äthern |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK136528B true DK136528B (da) | 1977-10-24 |
| DK136528C DK136528C (es) | 1978-03-28 |
Family
ID=4438418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK680869AA DK136528B (da) | 1968-12-24 | 1969-12-22 | Analogifremgangsmåde til fremstilling af aromatiske ethere eller disse forbindelsers syreadditionssalte eller de tilsvarende optisk aktive antipoder. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3701777A (es) |
| JP (3) | JPS495350B1 (es) |
| AT (4) | AT296314B (es) |
| BE (1) | BE743494A (es) |
| CA (1) | CA967965A (es) |
| CH (7) | CH506536A (es) |
| CS (2) | CS159258B2 (es) |
| DE (1) | DE1964423A1 (es) |
| DK (1) | DK136528B (es) |
| ES (1) | ES374836A1 (es) |
| FI (1) | FI53126C (es) |
| FR (1) | FR2027036B1 (es) |
| GB (1) | GB1290490A (es) |
| IL (1) | IL33508A (es) |
| MY (1) | MY7300260A (es) |
| NL (1) | NL6919400A (es) |
| NO (1) | NO126734B (es) |
| SE (1) | SE361666B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1325876A (en) * | 1969-08-15 | 1973-08-08 | Pfizer Ltd | Piperazine derivatives their preparation and pharmaceutical compositions containing them |
| GB1317479A (en) * | 1970-11-10 | 1973-05-16 | Pfizer Ltd | 1-2-hydroxy-3-phenoxy or phenylthiopropyl-4-phenyl-piperazine derivatives |
| US3951983A (en) * | 1970-11-10 | 1976-04-20 | Pfizer Inc. | Phenoxypropanolpiperazines |
| US3930004A (en) * | 1970-11-10 | 1975-12-30 | Pfizer | Method of using phenoxypropanolpiperazine compounds to lower blood pressure |
| FR2154493B1 (es) * | 1971-09-13 | 1975-10-31 | Kali Chemie Ag | |
| BE792187A (fr) * | 1971-12-03 | 1973-03-30 | Sumitomo Chemical Co | Nouveaux derives d'alkylamines |
| NL175059C (nl) * | 1974-02-23 | Boehringer Mannheim Gmbh | Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten. | |
| GB1583372A (en) * | 1977-04-04 | 1981-01-28 | Degussa | 1-(3-(3,4,5-trimethoxyphenoxy)-2-hydroxypropyl)-4-aryl piperazine derivatives |
| US4336382A (en) * | 1979-09-06 | 1982-06-22 | Hoffmann-La Roche Inc. | 1,4-Disubstituted piperazine compounds |
| JPS58164583A (ja) * | 1982-03-18 | 1983-09-29 | Nippon Shinyaku Co Ltd | フエノキシプロパノ−ルアミン誘導体 |
| US4616017A (en) * | 1984-06-04 | 1986-10-07 | Merck & Co., Inc. | Aminohydroxypropoxy substituted aryl compounds |
| FR2568878B1 (fr) * | 1984-08-07 | 1986-11-21 | Cortial | Nouveaux derives de (phenylpiperazinylethylamine ethoxy)-4 phenol, leur methode de preparation et leur application therapeutique |
| EP0179009A1 (fr) * | 1984-09-19 | 1986-04-23 | Cortial S.A. | Nouvelles n1-(aminoalcoxy)-4 isopropyl-5 phénoxy)-2 éthyl n4-phényl pipérazines, leur méthode de préparation et leur application thérapeutique |
| GB8619472D0 (en) * | 1986-08-09 | 1986-09-17 | Pfizer Ltd | Anti-arrhythmia agents |
| US4906634A (en) * | 1988-03-08 | 1990-03-06 | Schering A.G. | Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents |
| FR2632641B1 (fr) * | 1988-06-13 | 1990-10-12 | Irceba | ((aryl-4-piperazinyl-1)-2 ethoxy)-3 p-cymene, les derives ortho, meta, para monosubstitues ou disubstitues sur le noyau phenyle dudit produit, le procede de preparation desdits derives, et les medicaments contenant lesdits composes comme principe actif |
| US5051423A (en) * | 1988-07-13 | 1991-09-24 | Schering Ag | Derivatized alkanolamines as cardiovascular agents |
| US5614526A (en) * | 1995-06-09 | 1997-03-25 | Hoffmann-La Roche Inc. | Use of phenoxy-piperzine derivatives |
| ES2241169T3 (es) | 1997-10-31 | 2005-10-16 | Daiichi Suntory Pharma Co., Ltd. | Derivados de arilpiperidinopropanol y arilpiperazinopropanol y productos farmaceuticos que los contienen. |
| WO2013169964A1 (en) * | 2012-05-09 | 2013-11-14 | Sunovion Pharmaceuticals Inc. | Heteroaryl compounds and methods of use thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1382420A (fr) * | 1963-01-14 | 1964-12-18 | Ciba Geigy | Procédé pour la préparation de diaza-cyclo-alcanes, entre autres de la 1-(2-hydroxy-3-phénoxy-propyl)-4-(2-méthyl-phényl)-pipérazine |
-
0
- CA CA069*7A patent/CA967965A/en not_active Expired
-
1968
- 1968-12-24 CH CH257471A patent/CH506536A/de not_active IP Right Cessation
- 1968-12-24 CH CH256971A patent/CH521354A/de not_active IP Right Cessation
- 1968-12-24 CH CH257171A patent/CH521356A/de not_active IP Right Cessation
- 1968-12-24 CH CH1926968A patent/CH528516A/de not_active IP Right Cessation
- 1968-12-24 CH CH257071A patent/CH521355A/de not_active IP Right Cessation
- 1968-12-24 CH CH257271A patent/CH506534A/de not_active IP Right Cessation
- 1968-12-24 CH CH257371A patent/CH506535A/de not_active IP Right Cessation
-
1969
- 1969-12-04 US US882297A patent/US3701777A/en not_active Expired - Lifetime
- 1969-12-09 IL IL6933508A patent/IL33508A/xx unknown
- 1969-12-16 GB GB1290490D patent/GB1290490A/en not_active Expired
- 1969-12-19 FI FI3703/69A patent/FI53126C/fi active
- 1969-12-22 DK DK680869AA patent/DK136528B/da unknown
- 1969-12-22 BE BE743494D patent/BE743494A/xx unknown
- 1969-12-22 CS CS845769A patent/CS159258B2/cs unknown
- 1969-12-22 CS CS798972*1A patent/CS159259B2/cs unknown
- 1969-12-23 SE SE17878/69A patent/SE361666B/xx unknown
- 1969-12-23 FR FR696944582A patent/FR2027036B1/fr not_active Expired
- 1969-12-23 AT AT1199569A patent/AT296314B/de not_active IP Right Cessation
- 1969-12-23 NO NO695111A patent/NO126734B/no unknown
- 1969-12-23 AT AT199271A patent/AT296318B/de not_active IP Right Cessation
- 1969-12-23 AT AT199171A patent/AT296317B/de not_active IP Right Cessation
- 1969-12-23 ES ES374836A patent/ES374836A1/es not_active Expired
- 1969-12-23 AT AT01993/71A patent/AT296319B/de not_active IP Right Cessation
- 1969-12-23 DE DE19691964423 patent/DE1964423A1/de active Pending
- 1969-12-24 NL NL6919400A patent/NL6919400A/xx unknown
-
1971
- 1971-03-16 JP JP46014651A patent/JPS495350B1/ja active Pending
- 1971-03-16 JP JP46014649A patent/JPS495348B1/ja active Pending
- 1971-03-16 JP JP46014650A patent/JPS495349B1/ja active Pending
-
1973
- 1973-12-30 MY MY260/73A patent/MY7300260A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2027036B1 (es) | 1973-01-12 |
| IL33508A (en) | 1974-05-16 |
| NL6919400A (es) | 1970-06-26 |
| CS159259B2 (es) | 1974-12-27 |
| FI53126B (es) | 1977-10-31 |
| JPS495350B1 (es) | 1974-02-06 |
| CH506535A (de) | 1971-04-30 |
| CH506536A (de) | 1971-04-30 |
| CH528516A (de) | 1972-09-30 |
| NO126734B (es) | 1973-03-19 |
| DK136528C (es) | 1978-03-28 |
| AT296318B (de) | 1972-02-10 |
| IL33508A0 (en) | 1970-02-19 |
| FI53126C (es) | 1978-02-10 |
| AT296319B (de) | 1972-01-15 |
| SE361666B (es) | 1973-11-12 |
| CH506534A (de) | 1971-04-30 |
| US3701777A (en) | 1972-10-31 |
| ES374836A1 (es) | 1972-01-16 |
| DE1964423A1 (de) | 1970-07-30 |
| CH521355A (de) | 1972-04-15 |
| BE743494A (es) | 1970-06-22 |
| FR2027036A1 (es) | 1970-09-25 |
| GB1290490A (es) | 1972-09-27 |
| CS159258B2 (es) | 1974-12-27 |
| CA967965A (en) | 1975-05-20 |
| JPS495348B1 (es) | 1974-02-06 |
| JPS495349B1 (es) | 1974-02-06 |
| AT296314B (de) | 1972-02-10 |
| CH521354A (de) | 1972-04-15 |
| AT296317B (de) | 1972-02-10 |
| CH521356A (de) | 1972-04-15 |
| MY7300260A (en) | 1973-12-31 |
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