DK1359934T3 - Tripeptider og tripeptidderivater til behandling af neurodegenerative sygdomme - Google Patents
Tripeptider og tripeptidderivater til behandling af neurodegenerative sygdommeInfo
- Publication number
- DK1359934T3 DK1359934T3 DK02711833T DK02711833T DK1359934T3 DK 1359934 T3 DK1359934 T3 DK 1359934T3 DK 02711833 T DK02711833 T DK 02711833T DK 02711833 T DK02711833 T DK 02711833T DK 1359934 T3 DK1359934 T3 DK 1359934T3
- Authority
- DK
- Denmark
- Prior art keywords
- sub
- alkyl
- alkoxy
- tripeptides
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10105041A DE10105041A1 (de) | 2001-02-05 | 2001-02-05 | Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
PCT/EP2002/001180 WO2002062828A2 (fr) | 2001-02-05 | 2002-02-05 | Tripeptides derives de tripeptides utilises dans le traitement d'affections neurodegeneratives |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1359934T3 true DK1359934T3 (da) | 2007-03-12 |
Family
ID=7672834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02711833T DK1359934T3 (da) | 2001-02-05 | 2002-02-05 | Tripeptider og tripeptidderivater til behandling af neurodegenerative sygdomme |
Country Status (11)
Country | Link |
---|---|
US (1) | US7129213B2 (fr) |
EP (1) | EP1359934B1 (fr) |
JP (1) | JP4169597B2 (fr) |
AT (1) | ATE344673T1 (fr) |
AU (1) | AU2002231771A1 (fr) |
CY (1) | CY1107990T1 (fr) |
DE (2) | DE10105041A1 (fr) |
DK (1) | DK1359934T3 (fr) |
ES (1) | ES2275849T3 (fr) |
PT (1) | PT1359934E (fr) |
WO (1) | WO2002062828A2 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10105040A1 (de) * | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
DE10105041A1 (de) | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
DE10105038B4 (de) | 2001-02-05 | 2005-07-07 | Neurotell Ag | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
CA2491041A1 (fr) * | 2002-07-02 | 2004-01-15 | Novartis Ag | Inhibiteurs peptidiques de la liaison de la proteine smac avec les proteines inhibitrices de l'apoptose (iap) |
US20100166859A1 (en) * | 2006-01-16 | 2010-07-01 | Luppo Edens | Novel nutraceutical compositions and use thereof |
US7838971B2 (en) * | 2006-07-11 | 2010-11-23 | Atmel Corporation | Method to provide substrate-ground coupling for semiconductor integrated circuit dice constructed from SOI and related materials in stacked-die packages |
JP2013500986A (ja) | 2009-07-29 | 2013-01-10 | ザ・ユニバーシティ・オブ・シカゴ | 肝臓x受容体アゴニスト |
JP6344796B2 (ja) * | 2014-09-30 | 2018-06-20 | 森永乳業株式会社 | 高齢者用アルツハイマー型認知症改善剤 |
JP6589011B2 (ja) * | 2018-05-17 | 2019-10-09 | 森永乳業株式会社 | 脳機能障害改善用経口組成物 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1323301C (fr) | 1987-06-05 | 1993-10-19 | Alan I. Faden | Hormones de synthese liberant de la thyrotropine pour le traitement de lesions du systeme nerveux central |
FR2622581B1 (fr) * | 1987-11-03 | 1990-02-16 | Inorgan Sa Rech Develop Pharm | Nouveaux derives de l-proline, leur preparation et leurs applications biologiques |
DE69124274T2 (de) * | 1990-02-27 | 1997-08-14 | Agency Ind Science Techn | Oligopeptide, sie enthaltende pharmazeutische und Futterzusammensetzung und Benützung von Oligopeptiden |
DE4007869A1 (de) | 1990-03-13 | 1991-09-19 | Merck Patent Gmbh | Aminosaeurederivate |
JPH045240A (ja) * | 1990-04-20 | 1992-01-09 | Taisho Pharmaceut Co Ltd | 抗痴呆剤 |
US5091391A (en) * | 1990-08-16 | 1992-02-25 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Method of resisting neurodegenerative disorders |
AU667463B2 (en) * | 1990-12-28 | 1996-03-28 | Cortex Pharmaceuticals, Inc. | Use of calpain inhibitors in the inhibition and treatment of neurodegeneration |
WO1992013549A1 (fr) * | 1991-02-07 | 1992-08-20 | Research Corporation Technologies, Inc. | Inhibition de la proliferation des cellules a l'aide de peptides hydrophobes |
US6235929B1 (en) * | 1991-12-27 | 2001-05-22 | Georgia Tech Research Corporation | Tripeptide α-ketoamides |
PL322706A1 (en) * | 1993-11-09 | 1998-02-16 | Merck & Co Inc | Piperidines, pyrolidines and hexahydro-1h-azepins enhancing growth hormone liberation |
JP2800877B2 (ja) * | 1993-12-28 | 1998-09-21 | 伊藤ハム株式会社 | 血中トリグリセリド濃度上昇抑制ペプチド及び当該ペプチドを有効成分として含む血中トリグリセリド濃度上昇抑制剤 |
ZA95260B (en) * | 1994-01-13 | 1995-09-28 | Univ Columbia | Synthetic receptors libraries and uses thereof |
US5716929A (en) * | 1994-06-17 | 1998-02-10 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
US5834029A (en) * | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
JPH0940577A (ja) * | 1995-05-24 | 1997-02-10 | Mitsui Toatsu Chem Inc | トリペプチド、ジペプチドを含有する医薬組成物 |
EP0840614A1 (fr) | 1995-06-13 | 1998-05-13 | Sanofi Winthrop, Inc. | Inhibiteurs de la calpaine destines au traitement de maladies neurodegeneratives |
EP0838474B1 (fr) * | 1995-06-23 | 2005-03-30 | Mg Pharma Inc. | Peptide qui inhibe l'elevation du niveau de triglyceride dans le sang, et inhibiteur d'elevation de ce niveau contenant ledit peptide comme principe actif |
JPH09169797A (ja) * | 1995-12-22 | 1997-06-30 | Mitsui Toatsu Chem Inc | プロテアーゼアクティベーター活性を有するペプチド |
US5840838A (en) * | 1996-02-29 | 1998-11-24 | University Of Kentucky Research Foundation | Process for enhancing the activity of amyloid β peptides |
JP2805194B2 (ja) * | 1996-03-22 | 1998-09-30 | 阪急共栄物産株式会社 | 血中トリグリセリド濃度上昇抑制ペプチド及び当該ペプチドを有効成分として含む血中トリグリセリド濃度上昇抑制剤 |
AU743412B2 (en) * | 1996-10-04 | 2002-01-24 | Neuren Pharmaceuticals Limited | Regulation of neural enzymes |
JP4727770B2 (ja) * | 1997-09-26 | 2011-07-20 | カルピス株式会社 | 尿中カテコールアミン低下、尿中ノルアドレナリン低下、尿中ドーパミン低下及びFischer比低下の少なくとも1つの軽減剤 |
JPH11124398A (ja) * | 1997-10-22 | 1999-05-11 | Japan Energy Corp | C型肝炎ウイルス由来の抗原ペプチドとそれを用いる抗体検査薬 |
JP3108675B2 (ja) * | 1998-03-17 | 2000-11-13 | 阪急共栄物産株式会社 | 脂質代謝改善剤 |
US6080848A (en) * | 1998-05-01 | 2000-06-27 | Incyte Pharmaceuticals, Inc. | Human brain associated protein |
WO2001028578A2 (fr) | 1999-10-22 | 2001-04-26 | Wrair | Composition pharmaceutique a base de pglu-glu-pro-nh2 et procede de traitement de maladies et de lesions cerebrales |
JP4633876B2 (ja) * | 1999-11-11 | 2011-02-16 | カルピス株式会社 | トリペプチドの製造方法 |
WO2001068114A1 (fr) * | 2000-03-10 | 2001-09-20 | Monsanto Company | Nouveaux peptides a activite hypotensive |
DE10105038B4 (de) | 2001-02-05 | 2005-07-07 | Neurotell Ag | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
DE10105041A1 (de) | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
US6846641B2 (en) * | 2002-04-23 | 2005-01-25 | Agy Therapeutics, Inc. | In vitro ischemia model |
-
2001
- 2001-02-05 DE DE10105041A patent/DE10105041A1/de not_active Withdrawn
-
2002
- 2002-02-05 JP JP2002563180A patent/JP4169597B2/ja not_active Expired - Fee Related
- 2002-02-05 WO PCT/EP2002/001180 patent/WO2002062828A2/fr active IP Right Grant
- 2002-02-05 AU AU2002231771A patent/AU2002231771A1/en not_active Abandoned
- 2002-02-05 AT AT02711833T patent/ATE344673T1/de not_active IP Right Cessation
- 2002-02-05 EP EP02711833A patent/EP1359934B1/fr not_active Expired - Lifetime
- 2002-02-05 DE DE60215917T patent/DE60215917T2/de not_active Expired - Lifetime
- 2002-02-05 DK DK02711833T patent/DK1359934T3/da active
- 2002-02-05 ES ES02711833T patent/ES2275849T3/es not_active Expired - Lifetime
- 2002-02-05 PT PT02711833T patent/PT1359934E/pt unknown
-
2003
- 2003-08-05 US US10/635,797 patent/US7129213B2/en not_active Expired - Fee Related
-
2007
- 2007-01-08 CY CY20071100018T patent/CY1107990T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO2002062828A3 (fr) | 2002-10-10 |
JP4169597B2 (ja) | 2008-10-22 |
ATE344673T1 (de) | 2006-11-15 |
ES2275849T3 (es) | 2007-06-16 |
US20050101538A1 (en) | 2005-05-12 |
JP2004526704A (ja) | 2004-09-02 |
PT1359934E (pt) | 2007-01-31 |
DE60215917D1 (de) | 2006-12-21 |
EP1359934B1 (fr) | 2006-11-08 |
CY1107990T1 (el) | 2013-09-04 |
AU2002231771A1 (en) | 2002-08-19 |
EP1359934A2 (fr) | 2003-11-12 |
DE10105041A1 (de) | 2002-08-14 |
US7129213B2 (en) | 2006-10-31 |
WO2002062828A2 (fr) | 2002-08-15 |
DE60215917T2 (de) | 2007-09-13 |
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