DK1357953T3 - Transplantater til reparation af osteochondrale defekter - Google Patents

Transplantater til reparation af osteochondrale defekter

Info

Publication number
DK1357953T3
DK1357953T3 DK02726105T DK02726105T DK1357953T3 DK 1357953 T3 DK1357953 T3 DK 1357953T3 DK 02726105 T DK02726105 T DK 02726105T DK 02726105 T DK02726105 T DK 02726105T DK 1357953 T3 DK1357953 T3 DK 1357953T3
Authority
DK
Denmark
Prior art keywords
transplants
repair
osteochondral defects
dimensional matrix
constituted
Prior art date
Application number
DK02726105T
Other languages
Danish (da)
English (en)
Inventor
Lanfranco Callegaro
Alessandra Pavesio
Original Assignee
Fidia Advanced Biopolymers Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Advanced Biopolymers Srl filed Critical Fidia Advanced Biopolymers Srl
Application granted granted Critical
Publication of DK1357953T3 publication Critical patent/DK1357953T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817Cartilage-forming cells, e.g. pre-chondrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843Connective tissue
    • A61L27/3852Cartilage, e.g. meniscus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Urology & Nephrology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Dental Preparations (AREA)
  • Earth Drilling (AREA)
  • Excavating Of Shafts Or Tunnels (AREA)
  • Cultivation Of Seaweed (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Cosmetics (AREA)
DK02726105T 2001-02-09 2002-02-06 Transplantater til reparation af osteochondrale defekter DK1357953T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001PD000032A ITPD20010032A1 (it) 2001-02-09 2001-02-09 Innesti ingegnerizzati per la riparazione di difetti osteocondrali

Publications (1)

Publication Number Publication Date
DK1357953T3 true DK1357953T3 (da) 2006-01-16

Family

ID=11452207

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02726105T DK1357953T3 (da) 2001-02-09 2002-02-06 Transplantater til reparation af osteochondrale defekter

Country Status (11)

Country Link
US (1) US7968111B2 (fr)
EP (1) EP1357953B1 (fr)
JP (1) JP2004524904A (fr)
AT (1) ATE309007T1 (fr)
AU (1) AU2002256617B8 (fr)
CA (1) CA2437440C (fr)
DE (1) DE60207198T2 (fr)
DK (1) DK1357953T3 (fr)
ES (1) ES2250642T3 (fr)
IT (1) ITPD20010032A1 (fr)
WO (1) WO2002070030A1 (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10260958A1 (de) * 2002-12-20 2004-07-08 Sustech Gmbh & Co. Kg Kompositmaterialien aus Calciumverbindungen und Glucuronsäure- und/oder Iduronsäurehaltigen Polysacchariden
US8173162B2 (en) 2003-02-26 2012-05-08 Zimmer Orthobiologics, Inc. Preparation for repairing cartilage tissue, especially articular cartilage defects
US20050074877A1 (en) * 2003-07-28 2005-04-07 Mao Jeremy Jian Biological engineering of articular structures containing both cartilage and bone
ITPD20030286A1 (it) * 2003-11-27 2005-05-28 Fidia Advanced Biopolymers Srl Strutture composite multistrato contenenti acido ialuronico
US7666230B2 (en) 2003-12-08 2010-02-23 Depuy Products, Inc. Implant device for cartilage regeneration in load bearing articulation regions
ITPD20040053A1 (it) * 2004-02-27 2004-05-27 Fidia Advanced Biopolymers Srl Biomateriali costituiti da derivati dell'acido ialuronico come nuova terapia di cura per la protezione e la la riparazione della cartilagine articolare danneggiata per osteoartrosi
CA2577108A1 (fr) 2004-08-31 2006-03-09 C.R. Bard, Inc. Greffe en polytetrafluorethylene (ptfe) auto-etanche a resistance au tortillement
EP1887968A4 (fr) * 2005-06-08 2013-01-23 Bard Inc C R Greffes et stents revetus de sel de calcium biocompatible
EP1890641B1 (fr) 2005-06-17 2017-04-19 C.R. Bard, Inc. Greffon vasculaire avec une résistance au pliage après le clampage
DE102005030614B4 (de) * 2005-06-30 2014-05-08 Biotissue Ag Zellfreies Transplantat, dessen Verwendung, Verfahren zu dessen Herstellung, dabei hergestellte Matrix mit Gel und Verfahren zur Herstellung dieser Matrix mit Gel
WO2007007062A2 (fr) * 2005-07-08 2007-01-18 Depuy International Limited Implant pour reparation de cartilage
EP1764117A1 (fr) 2005-09-20 2007-03-21 Zimmer GmbH Implant pour la réparation de défauts cartilagineux et son procédé de préparation
WO2007056761A2 (fr) 2005-11-09 2007-05-18 C.R. Bard Inc. Greffons et stents-greffons presentant un marqueur radio-opaque
CN100398496C (zh) * 2005-12-29 2008-07-02 武汉理工大学 层状多孔磷酸钙生物陶瓷的制备方法及其应用
JP5173199B2 (ja) * 2006-01-16 2013-03-27 株式会社アイ・ティー・オー 創傷治癒用高分子組成物
JP5538493B2 (ja) * 2006-01-16 2014-07-02 株式会社アイ・ティー・オー 生体内組織用創傷治癒用フィルム及び生体内接着用フィルム
DE102006047346A1 (de) * 2006-10-06 2008-04-10 Transtissue Technologies Gmbh Matrix-Gel-Transplantat ohne Zellen
EP2079575B1 (fr) 2006-10-12 2021-06-02 C.R. Bard, Inc. Procédés de fabrication de greffons vasculaires à multiples canaux
WO2008049281A1 (fr) * 2006-10-27 2008-05-02 Beijing Institute Of Transfusion Medicine Procédé de construction d'une construction de génie tissulaire hépatique et construction de génie tissulaire hépatique
JP6062615B2 (ja) * 2007-08-06 2017-01-18 メゾブラスト,インコーポレーテッド インビボで結合組織を生成、修復、および/または維持するための方法
AU2013203054B2 (en) * 2007-08-06 2017-05-18 Mesoblast, Inc. Methods of generating, repairing and/or maintaining connective tissue in vivo
US8535913B2 (en) * 2008-01-30 2013-09-17 Histogen, Inc. Soluble composition for promoting hair growth produced by hypoxic culture of fibroblasts cells
US8530415B2 (en) * 2008-01-30 2013-09-10 Histogen, Inc. Repair and/or regeneration of cells with a composition produced by culturing fibroblast cells under hypoxic conditions
BRPI0906972B1 (pt) * 2008-01-30 2021-09-08 Histogen, Inc Métodos para produção de composições de matriz extracelular e para produção de uma proteína wnt e de um fator de crescimento endotelial vascular
US8524494B2 (en) 2008-01-30 2013-09-03 Histogen, Inc. Low oxygen tension and BFGF generates a multipotent stem cell from a fibroblast in vitro
CN105030828B (zh) 2008-06-25 2020-10-02 麦瑟布莱斯特公司 椎间盘的修复和/或重建
CA2767600C (fr) * 2009-07-10 2022-05-31 Histogen, Inc. Compositions a base de milieu conditionne et de matrice extracellulaire a partir de cellules cultivees dans des conditions hypoxiques
WO2012051420A2 (fr) 2010-10-13 2012-04-19 Cibor, Inc. Greffons osseux synthétiques construits à partir de matériaux alvéolaires à base de carbone
WO2012099852A1 (fr) 2011-01-17 2012-07-26 Cibor, Inc. Dispositif de fusion de colonne vertébrale en fibre de carbone/mousse de carbone renforcée
KR101306748B1 (ko) * 2012-03-29 2013-09-10 주식회사 바이오알파 성장인자 전달속도 조절이 가능한 히알루론산-인산칼슘 복합체 및 그 제조방법
WO2014041516A1 (fr) 2012-09-14 2014-03-20 Ecole Polytechnique Federale De Lausanne (Epfl) Structure multicouche biocompatible comprenant des couches de mousse et une interface fonctionnelle
EP2945655B1 (fr) 2013-01-15 2019-09-25 Tepha, Inc. Implants pour la régénérescence de tissu mou et dur
WO2018097198A1 (fr) * 2016-11-28 2018-05-31 株式会社バイオ未来工房 Procédé de séparation de cellules souches mésenchymateuses, et application de tissu non-tissé comprenant un phosphate de calcium
EP3735204B1 (fr) 2018-01-02 2023-09-06 Cartiheal (2009) Ltd. Outil d'implantation pour substrats solides optimisés favorisant la croissance cellulaire et tissulaire
CN112552035A (zh) * 2020-12-11 2021-03-26 湖北联结生物材料有限公司 一种可诱导生物活性3d打印陶瓷及其制备方法
CN115317672B (zh) * 2022-08-27 2023-11-14 四川大学 仿生骨软骨一体化修复植入体及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9101853D0 (sv) * 1991-06-17 1991-06-17 Jonas Wadstroem Improved tissue ashesive
IT1259090B (it) * 1992-04-17 1996-03-11 Fidia Spa Biomaterialli per protesi d'osso
IT1263316B (it) 1993-02-12 1996-08-05 Fidia Advanced Biopolymers Srl Tessuto non tessuto multistrato in cui uno degli strati e' costituito essenzialmente da esteri dell'acido ialuronico
WO1997045532A1 (fr) * 1996-05-28 1997-12-04 Brown University Research Foundation Charpentes biodegradables a base de hyaluronan destinees a la reparation tissulaire
DE19803673A1 (de) * 1998-01-30 1999-08-05 Norbert M Dr Meenen Biohybrider Gelenkflächenersatz
US6872819B1 (en) 1998-05-27 2005-03-29 Fidia Advanced Biopolymers S.R.L. Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells
ITPD980149A1 (it) 1998-06-17 1999-12-17 Fidia Advanced Biopolymers Srl Protesi tridimensionali comprendenti derivati dell'acido ialuronico per riparare o ricostruire i tessuti danneggiati e processo per la
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
IT1302534B1 (it) 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
US6656489B1 (en) * 1999-02-10 2003-12-02 Isotis N.V. Scaffold for tissue engineering cartilage having outer surface layers of copolymer and ceramic material
IT1306644B1 (it) 1999-04-08 2001-10-02 Fidia Advanced Biopolymers Srl Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico.

Also Published As

Publication number Publication date
WO2002070030A8 (fr) 2002-12-05
DE60207198T2 (de) 2006-06-01
ES2250642T3 (es) 2006-04-16
ATE309007T1 (de) 2005-11-15
ITPD20010032A1 (it) 2002-08-09
AU2002256617B8 (en) 2007-02-15
US20040076656A1 (en) 2004-04-22
WO2002070030A1 (fr) 2002-09-12
JP2004524904A (ja) 2004-08-19
CA2437440C (fr) 2012-04-03
US7968111B2 (en) 2011-06-28
CA2437440A1 (fr) 2002-09-12
EP1357953A1 (fr) 2003-11-05
DE60207198D1 (de) 2005-12-15
AU2002256617B2 (en) 2007-02-08
EP1357953B1 (fr) 2005-11-09

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