ATE309007T1 - Transplantate für die wiederherstellung von osteochondralen schäden - Google Patents

Transplantate für die wiederherstellung von osteochondralen schäden

Info

Publication number
ATE309007T1
ATE309007T1 AT02726105T AT02726105T ATE309007T1 AT E309007 T1 ATE309007 T1 AT E309007T1 AT 02726105 T AT02726105 T AT 02726105T AT 02726105 T AT02726105 T AT 02726105T AT E309007 T1 ATE309007 T1 AT E309007T1
Authority
AT
Austria
Prior art keywords
transplants
restoration
dimensional matrix
osteochondral damage
constituted
Prior art date
Application number
AT02726105T
Other languages
English (en)
Inventor
Alessandra Pavesio
Lanfranco Callegaro
Original Assignee
Fidia Advanced Biopolymers Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Advanced Biopolymers Srl filed Critical Fidia Advanced Biopolymers Srl
Application granted granted Critical
Publication of ATE309007T1 publication Critical patent/ATE309007T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
AT02726105T 2001-02-09 2002-02-06 Transplantate für die wiederherstellung von osteochondralen schäden ATE309007T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001PD000032A ITPD20010032A1 (it) 2001-02-09 2001-02-09 Innesti ingegnerizzati per la riparazione di difetti osteocondrali
PCT/EP2002/001224 WO2002070030A1 (en) 2001-02-09 2002-02-06 Grafts for the repair of osteochondral defects

Publications (1)

Publication Number Publication Date
ATE309007T1 true ATE309007T1 (de) 2005-11-15

Family

ID=11452207

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02726105T ATE309007T1 (de) 2001-02-09 2002-02-06 Transplantate für die wiederherstellung von osteochondralen schäden

Country Status (11)

Country Link
US (1) US7968111B2 (de)
EP (1) EP1357953B1 (de)
JP (1) JP2004524904A (de)
AT (1) ATE309007T1 (de)
AU (1) AU2002256617B8 (de)
CA (1) CA2437440C (de)
DE (1) DE60207198T2 (de)
DK (1) DK1357953T3 (de)
ES (1) ES2250642T3 (de)
IT (1) ITPD20010032A1 (de)
WO (1) WO2002070030A1 (de)

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US8173162B2 (en) 2003-02-26 2012-05-08 Zimmer Orthobiologics, Inc. Preparation for repairing cartilage tissue, especially articular cartilage defects
US20050074877A1 (en) * 2003-07-28 2005-04-07 Mao Jeremy Jian Biological engineering of articular structures containing both cartilage and bone
ITPD20030286A1 (it) 2003-11-27 2005-05-28 Fidia Advanced Biopolymers Srl Strutture composite multistrato contenenti acido ialuronico
US7666230B2 (en) 2003-12-08 2010-02-23 Depuy Products, Inc. Implant device for cartilage regeneration in load bearing articulation regions
ITPD20040053A1 (it) * 2004-02-27 2004-05-27 Fidia Advanced Biopolymers Srl Biomateriali costituiti da derivati dell'acido ialuronico come nuova terapia di cura per la protezione e la la riparazione della cartilagine articolare danneggiata per osteoartrosi
CA2577108A1 (en) 2004-08-31 2006-03-09 C.R. Bard, Inc. Self-sealing ptfe graft with kink resistance
JP2008543376A (ja) * 2005-06-08 2008-12-04 シー・アール・バード・インコーポレーテッド 無機生体適合性カルシウム塩を有するグラフト及びステント
ES2625807T3 (es) 2005-06-17 2017-07-20 C.R. Bard, Inc. Injerto vascular con resistencia al retorcimiento tras la sujeción
DE102005030614B4 (de) * 2005-06-30 2014-05-08 Biotissue Ag Zellfreies Transplantat, dessen Verwendung, Verfahren zu dessen Herstellung, dabei hergestellte Matrix mit Gel und Verfahren zur Herstellung dieser Matrix mit Gel
WO2007007062A2 (en) * 2005-07-08 2007-01-18 Depuy International Limited Cartilage repair implant
EP1764117A1 (de) 2005-09-20 2007-03-21 Zimmer GmbH Implantat zur Wiederherstellung von Knorpeldefekten und Verfahren zu seiner Herstellung
WO2007056761A2 (en) 2005-11-09 2007-05-18 C.R. Bard Inc. Grafts and stent grafts having a radiopaque marker
CN100398496C (zh) * 2005-12-29 2008-07-02 武汉理工大学 层状多孔磷酸钙生物陶瓷的制备方法及其应用
JP5538493B2 (ja) * 2006-01-16 2014-07-02 株式会社アイ・ティー・オー 生体内組織用創傷治癒用フィルム及び生体内接着用フィルム
JP5173199B2 (ja) * 2006-01-16 2013-03-27 株式会社アイ・ティー・オー 創傷治癒用高分子組成物
DE102006047346A1 (de) * 2006-10-06 2008-04-10 Transtissue Technologies Gmbh Matrix-Gel-Transplantat ohne Zellen
WO2008063780A2 (en) 2006-10-12 2008-05-29 C.R. Bard Inc. Vascular grafts with multiple channels and methods for making
WO2008049281A1 (fr) * 2006-10-27 2008-05-02 Beijing Institute Of Transfusion Medicine Procédé de construction d'une construction de génie tissulaire hépatique et construction de génie tissulaire hépatique
TWI603736B (zh) * 2007-08-06 2017-11-01 安吉歐公司 活體內產生、修補及／或維持結締組織的方法
AU2013203054B2 (en) * 2007-08-06 2017-05-18 Mesoblast, Inc. Methods of generating, repairing and/or maintaining connective tissue in vivo
US8530415B2 (en) * 2008-01-30 2013-09-10 Histogen, Inc. Repair and/or regeneration of cells with a composition produced by culturing fibroblast cells under hypoxic conditions
US8535913B2 (en) * 2008-01-30 2013-09-17 Histogen, Inc. Soluble composition for promoting hair growth produced by hypoxic culture of fibroblasts cells
AP3129A (en) * 2008-01-30 2015-02-28 Histogen Inc Extracellular matrix compositions
US8524494B2 (en) * 2008-01-30 2013-09-03 Histogen, Inc. Low oxygen tension and BFGF generates a multipotent stem cell from a fibroblast in vitro
ES2872337T3 (es) 2008-06-25 2021-11-02 Mesoblast Inc Células STRO-1bright para su uso en el tratamiento del dolor de espalda baja
KR101834019B1 (ko) * 2009-07-10 2018-03-02 히스토젠, 인코포레이티드 저산소 조건 하에 배양된 세포로부터의 조정 배지 및 세포외 기질 조성물
WO2012051420A2 (en) 2010-10-13 2012-04-19 Cibor, Inc. Synthetic bone grafts constructed from carbon foam materials
WO2012099852A1 (en) 2011-01-17 2012-07-26 Cibor, Inc. Reinforced carbon fiber/carbon foam intervertebral spine fusion device
KR101306748B1 (ko) * 2012-03-29 2013-09-10 주식회사 바이오알파 성장인자 전달속도 조절이 가능한 히알루론산-인산칼슘 복합체 및 그 제조방법
WO2014041516A1 (en) 2012-09-14 2014-03-20 Ecole Polytechnique Federale De Lausanne (Epfl) Biocompatible multi-layered structure comprising foam layers and a functional interface
ES2751398T3 (es) 2013-01-15 2020-03-31 Tepha Inc Implantes para regeneración de tejido blando y tejido duro
WO2018097198A1 (ja) * 2016-11-28 2018-05-31 株式会社バイオ未来工房 間葉系幹細胞の分離方法及びリン酸カルシウム類を含有する不織布の使用
US20200368027A1 (en) 2018-01-02 2020-11-26 Cartiheal (2009) Ltd. Implantation Tool and Protocol for Optimized Solid Substrates Promoting Cell and Tissue Growth
CN112552035A (zh) * 2020-12-11 2021-03-26 湖北联结生物材料有限公司 一种可诱导生物活性3d打印陶瓷及其制备方法
CN115317672B (zh) * 2022-08-27 2023-11-14 四川大学 仿生骨软骨一体化修复植入体及其制备方法与应用

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Also Published As

Publication number Publication date
CA2437440A1 (en) 2002-09-12
AU2002256617B8 (en) 2007-02-15
DK1357953T3 (da) 2006-01-16
WO2002070030A8 (en) 2002-12-05
AU2002256617B2 (en) 2007-02-08
US7968111B2 (en) 2011-06-28
WO2002070030A1 (en) 2002-09-12
ITPD20010032A1 (it) 2002-08-09
DE60207198T2 (de) 2006-06-01
EP1357953A1 (de) 2003-11-05
US20040076656A1 (en) 2004-04-22
EP1357953B1 (de) 2005-11-09
CA2437440C (en) 2012-04-03
JP2004524904A (ja) 2004-08-19
ES2250642T3 (es) 2006-04-16
DE60207198D1 (de) 2005-12-15

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