DK1343808T3 - Fremgangsmåde til syntese af et LHRA-peptid - Google Patents
Fremgangsmåde til syntese af et LHRA-peptidInfo
- Publication number
- DK1343808T3 DK1343808T3 DK01272223T DK01272223T DK1343808T3 DK 1343808 T3 DK1343808 T3 DK 1343808T3 DK 01272223 T DK01272223 T DK 01272223T DK 01272223 T DK01272223 T DK 01272223T DK 1343808 T3 DK1343808 T3 DK 1343808T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptide
- lhra
- synthesizing
- protecting group
- residue
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 230000002194 synthesizing effect Effects 0.000 title 1
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 125000001041 indolyl group Chemical group 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000010532 solid phase synthesis reaction Methods 0.000 abstract 1
- 125000000430 tryptophan group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/068—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for heterocyclic side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE20001079 | 2000-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1343808T3 true DK1343808T3 (da) | 2006-12-11 |
Family
ID=11042704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01272223T DK1343808T3 (da) | 2000-12-22 | 2001-12-19 | Fremgangsmåde til syntese af et LHRA-peptid |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7122628B2 (cs) |
| EP (1) | EP1343808B1 (cs) |
| JP (1) | JP4064817B2 (cs) |
| KR (1) | KR100591832B1 (cs) |
| CN (2) | CN1481389A (cs) |
| AT (1) | ATE339442T1 (cs) |
| AU (1) | AU2002222439C1 (cs) |
| BR (1) | BR0116447B1 (cs) |
| CA (1) | CA2432708C (cs) |
| CZ (1) | CZ299141B6 (cs) |
| DE (1) | DE60123115T2 (cs) |
| DK (1) | DK1343808T3 (cs) |
| ES (1) | ES2266104T3 (cs) |
| HU (2) | HU229701B1 (cs) |
| IE (1) | IES20011090A2 (cs) |
| IL (2) | IL156258A0 (cs) |
| MX (1) | MXPA03005678A (cs) |
| NO (1) | NO325038B1 (cs) |
| NZ (1) | NZ526990A (cs) |
| PL (1) | PL205949B1 (cs) |
| PT (1) | PT1343808E (cs) |
| RU (1) | RU2276156C2 (cs) |
| WO (1) | WO2002051861A2 (cs) |
| ZA (1) | ZA200304809B (cs) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7091311B2 (en) | 1996-06-07 | 2006-08-15 | Smithkline Beecham Corporation | Peptides and compounds that bind to a receptor |
| PL376085A1 (en) | 2002-09-18 | 2005-12-12 | Ortho-Mcneil Pharmaceutical, Inc. | Methods of increasing platelet and hematopoietic stem cell production |
| EP1675606B1 (en) * | 2003-08-28 | 2017-04-05 | Janssen Pharmaceuticals, Inc. | Peptides and compounds that bind to thrombopoietin receptors |
| EP1968995A1 (en) * | 2005-12-30 | 2008-09-17 | F. Hoffmann-la Roche AG | Methods for the synthesis of arginine-containing peptides |
| CN103517915B (zh) * | 2012-09-27 | 2015-11-25 | 深圳翰宇药业股份有限公司 | 一种制备布舍瑞林的方法 |
| US10308677B2 (en) | 2014-12-19 | 2019-06-04 | Cem Corporation | Coupling method for peptide synthesis at elevated temperatures |
| US9969769B2 (en) | 2014-12-19 | 2018-05-15 | Cem Corporation | Coupling method for peptide synthesis at elevated temperatures |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4211693A (en) * | 1977-09-20 | 1980-07-08 | The Salk Institute For Biological Studies | Peptides with para-substituted phenylalanine |
| US4569927A (en) * | 1984-02-23 | 1986-02-11 | The Salk Institute For Biological Studies | GnRH Antagonists IV |
| IL74827A (en) | 1984-05-21 | 1989-06-30 | Salk Inst For Biological Studi | Peptides active as gnrh antagonists and pharmaceutical compositions containing them |
| IT1203600B (it) | 1985-12-06 | 1989-02-15 | Phidea Srl | Metodo per preparare il (d-trp6)-lhrh |
| GB8822502D0 (en) * | 1988-09-24 | 1988-10-26 | Expansia Sa | New peptide synthesis method |
| US5175254A (en) * | 1988-09-24 | 1992-12-29 | Societe D'expansion Scientifque Expansia | Solid phase peptide synthesis using a polyacrylic support in aqueous solution |
| RU2043362C1 (ru) * | 1991-08-12 | 1995-09-10 | Синтекс (Ю-Эс-Эй) Инк. | Способ твердофазного синтеза пептидов |
| JPH05331188A (ja) | 1992-05-28 | 1993-12-14 | Nippon Chemiphar Co Ltd | トリペプチド、その製造方法及びエンドセリン拮抗剤 |
| RU2086561C1 (ru) * | 1995-09-25 | 1997-08-10 | Тихонов Александр Васильевич | Способ получения нонапептидэтиламида |
-
2001
- 2001-12-19 WO PCT/IE2001/000159 patent/WO2002051861A2/en not_active Ceased
- 2001-12-19 ES ES01272223T patent/ES2266104T3/es not_active Expired - Lifetime
- 2001-12-19 JP JP2002552954A patent/JP4064817B2/ja not_active Expired - Lifetime
- 2001-12-19 RU RU2003122779/04A patent/RU2276156C2/ru not_active IP Right Cessation
- 2001-12-19 NZ NZ526990A patent/NZ526990A/xx not_active IP Right Cessation
- 2001-12-19 MX MXPA03005678A patent/MXPA03005678A/es active IP Right Grant
- 2001-12-19 DE DE60123115T patent/DE60123115T2/de not_active Expired - Lifetime
- 2001-12-19 IL IL15625801A patent/IL156258A0/xx active IP Right Grant
- 2001-12-19 CN CNA018210384A patent/CN1481389A/zh active Pending
- 2001-12-19 KR KR1020037008232A patent/KR100591832B1/ko not_active Expired - Lifetime
- 2001-12-19 BR BRPI0116447-3B1A patent/BR0116447B1/pt active IP Right Grant
- 2001-12-19 CZ CZ20031634A patent/CZ299141B6/cs not_active IP Right Cessation
- 2001-12-19 HU HU0302633A patent/HU229701B1/hu unknown
- 2001-12-19 US US10/451,486 patent/US7122628B2/en not_active Expired - Lifetime
- 2001-12-19 HU HUP1400157A patent/HU230601B1/hu unknown
- 2001-12-19 DK DK01272223T patent/DK1343808T3/da active
- 2001-12-19 AU AU2002222439A patent/AU2002222439C1/en not_active Expired
- 2001-12-19 CN CNA2007100047879A patent/CN101003563A/zh active Pending
- 2001-12-19 PT PT01272223T patent/PT1343808E/pt unknown
- 2001-12-19 CA CA2432708A patent/CA2432708C/en not_active Expired - Lifetime
- 2001-12-19 PL PL361993A patent/PL205949B1/pl unknown
- 2001-12-19 EP EP01272223A patent/EP1343808B1/en not_active Expired - Lifetime
- 2001-12-19 AT AT01272223T patent/ATE339442T1/de active
- 2001-12-20 IE IE20011090A patent/IES20011090A2/en not_active IP Right Cessation
-
2003
- 2003-06-02 IL IL156258A patent/IL156258A/en unknown
- 2003-06-20 ZA ZA200304809A patent/ZA200304809B/en unknown
- 2003-06-20 NO NO20032852A patent/NO325038B1/no not_active IP Right Cessation
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