DK131789A - 1,3,4,5-tetrahydrobenz(c,d)indoler, fremgangsmaader til deres fremstilling samt deres anvendelse - Google Patents

1,3,4,5-tetrahydrobenz(c,d)indoler, fremgangsmaader til deres fremstilling samt deres anvendelse

Info

Publication number
DK131789A
DK131789A DK131789A DK131789A DK131789A DK 131789 A DK131789 A DK 131789A DK 131789 A DK131789 A DK 131789A DK 131789 A DK131789 A DK 131789A DK 131789 A DK131789 A DK 131789A
Authority
DK
Denmark
Prior art keywords
tetrahydrobenz
indoles
procedures
preparation
medicaments
Prior art date
Application number
DK131789A
Other languages
Danish (da)
English (en)
Other versions
DK131789D0 (da
Inventor
Bodo Junge
Bernd Richter
Thomas Glaser
Joerg Traber
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK131789D0 publication Critical patent/DK131789D0/da
Publication of DK131789A publication Critical patent/DK131789A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/90Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK131789A 1988-03-18 1989-03-17 1,3,4,5-tetrahydrobenz(c,d)indoler, fremgangsmaader til deres fremstilling samt deres anvendelse DK131789A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3809155A DE3809155A1 (de) 1988-03-18 1988-03-18 1,3,4,5-tetrahydrobenz-(c,d)-indole

Publications (2)

Publication Number Publication Date
DK131789D0 DK131789D0 (da) 1989-03-17
DK131789A true DK131789A (da) 1989-09-19

Family

ID=6350115

Family Applications (1)

Application Number Title Priority Date Filing Date
DK131789A DK131789A (da) 1988-03-18 1989-03-17 1,3,4,5-tetrahydrobenz(c,d)indoler, fremgangsmaader til deres fremstilling samt deres anvendelse

Country Status (18)

Country Link
US (1) US5021438A (pt)
EP (1) EP0332968B1 (pt)
JP (1) JPH02204479A (pt)
KR (1) KR890014474A (pt)
CN (1) CN1036566A (pt)
AT (1) ATE90093T1 (pt)
AU (1) AU614343B2 (pt)
DD (1) DD283606A5 (pt)
DE (2) DE3809155A1 (pt)
DK (1) DK131789A (pt)
ES (1) ES2058365T3 (pt)
FI (1) FI891252A (pt)
HU (1) HU204034B (pt)
IL (1) IL89623A (pt)
NO (1) NO890892L (pt)
NZ (1) NZ228341A (pt)
PT (1) PT90012B (pt)
ZA (1) ZA892049B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3826371A1 (de) * 1988-08-03 1990-02-08 Bayer Ag Tetrahydro-1-benz-(c,d)-indolpropionsaeure-sulfonamide
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
US5273975A (en) * 1989-06-09 1993-12-28 The Upjohn Company Heterocyclic amines having central nervous system activity
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
US5212319A (en) * 1990-02-26 1993-05-18 Eli Lilly And Company Intermediates to 4-amino-hexahydrobenz[cd]indoles and processes therefor
TW219933B (pt) * 1990-02-26 1994-02-01 Lilly Co Eli
US5264442A (en) * 1990-08-13 1993-11-23 Hoechst-Roussel Pharmaceuticals Incorporated Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs
EP0471298B1 (en) * 1990-08-13 1995-11-02 Hoechst-Roussel Pharmaceuticals Incorporated Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5347013A (en) * 1991-03-28 1994-09-13 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5244911A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
US5633273A (en) * 1991-03-28 1997-05-27 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd] indoles
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
NZ314570A (en) * 1993-06-10 2000-11-24 Lilly Co Eli Treatment of emesis using tetrahydrobenz[cd]indole-6-carboxamides
TW430660B (en) * 1996-05-30 2001-04-21 Mochida Pharm Co Ltd Novel benzindole derivatives for neuron cell protection, processes for production, and the pharmaceutical compounds containing them
NZ523526A (en) * 2000-07-20 2004-10-29 Neurogen Corp Diaryl piperazines as capsaicin receptor ligands
EP3931189A4 (en) 2019-02-27 2022-11-30 The Regents Of The University Of California AZEPINO-INDOLES AND OTHER HETEROCYCLES FOR TREATING BRAIN DISORDERS
JP2022523774A (ja) 2019-02-27 2022-04-26 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 脳障害を治療するためのn-置換インドール及び他の複素環化合物
WO2021076572A1 (en) * 2019-10-14 2021-04-22 The Regents Of The University Of California Ergoline-like compounds for promoting neural plasticity
CN115584206A (zh) * 2022-10-13 2023-01-10 吕辉 一种水性无机纳米陶瓷阻燃涂料及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE542760A (pt) * 1954-11-12
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4282240A (en) * 1979-11-23 1981-08-04 Merck & Co., Inc. Amino substituted tetrahydrobenzindoles
FR2471373A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux derives de la benzindolamine, leurs sels, procede de preparation, application a titre de medicaments et composition les renfermant
DE3346513A1 (de) 1983-12-22 1985-07-11 Süddeutsche Kühlerfabrik Julius Fr. Behr GmbH & Co. KG, 7000 Stuttgart Vorrichtung zum erwaermen von wasser
DE3346573A1 (de) * 1983-12-23 1985-07-04 Troponwerke GmbH & Co KG, 5000 Köln 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
IL74222A (en) * 1984-02-06 1988-07-31 Lilly Co Eli 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
US4683313A (en) * 1985-06-24 1987-07-28 Eli Lilly And Company 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
DE3718892A1 (de) * 1987-06-05 1988-12-22 Bayer Ag Polyhydrobenz(c,d)indol-sulfonamide

Also Published As

Publication number Publication date
FI891252A (fi) 1989-09-19
HUT50767A (en) 1990-03-28
CN1036566A (zh) 1989-10-25
AU3152689A (en) 1989-09-28
JPH02204479A (ja) 1990-08-14
EP0332968A1 (de) 1989-09-20
PT90012B (pt) 1994-06-30
US5021438A (en) 1991-06-04
ES2058365T3 (es) 1994-11-01
EP0332968B1 (de) 1993-06-02
IL89623A (en) 1993-01-14
DK131789D0 (da) 1989-03-17
HU204034B (en) 1991-11-28
ZA892049B (en) 1989-11-29
DD283606A5 (de) 1990-10-17
NZ228341A (en) 1990-12-21
AU614343B2 (en) 1991-08-29
KR890014474A (ko) 1989-10-23
DE58904539D1 (de) 1993-07-08
DE3809155A1 (de) 1989-09-28
FI891252A0 (fi) 1989-03-16
PT90012A (pt) 1989-11-10
ATE90093T1 (de) 1993-06-15
NO890892L (no) 1989-09-19
IL89623A0 (en) 1989-09-10
NO890892D0 (no) 1989-03-02

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