DK581183A - 2-azabicyclo(2.2.1)heptan-derivater, fremgangsmaader til deres fremstilling, midler indeholdende disse derivater og deres anvendelse, samt 2-azabicyclo(2.2.1)heptan-derivater som mellemprodukter samt fremgangsmaader til deres fremstilling - Google Patents

2-azabicyclo(2.2.1)heptan-derivater, fremgangsmaader til deres fremstilling, midler indeholdende disse derivater og deres anvendelse, samt 2-azabicyclo(2.2.1)heptan-derivater som mellemprodukter samt fremgangsmaader til deres fremstilling Download PDF

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Publication number
DK581183A
DK581183A DK581183A DK581183A DK581183A DK 581183 A DK581183 A DK 581183A DK 581183 A DK581183 A DK 581183A DK 581183 A DK581183 A DK 581183A DK 581183 A DK581183 A DK 581183A
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DK
Denmark
Prior art keywords
derivatives
heptan
azabicyclo
procedures
preparation
Prior art date
Application number
DK581183A
Other languages
English (en)
Other versions
DK581183D0 (da
Inventor
Rainer Henning
Hansjoerg Urbach
Reinhard Becker
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK581183D0 publication Critical patent/DK581183D0/da
Publication of DK581183A publication Critical patent/DK581183A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK581183A 1982-12-17 1983-12-16 2-azabicyclo(2.2.1)heptan-derivater, fremgangsmaader til deres fremstilling, midler indeholdende disse derivater og deres anvendelse, samt 2-azabicyclo(2.2.1)heptan-derivater som mellemprodukter samt fremgangsmaader til deres fremstilling DK581183A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823246757 DE3246757A1 (de) 1982-12-17 1982-12-17 Neue 2-azabicyclo(2.2.1)heptan-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(2.2.1)heptan-derivate als zwischenprodukte und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
DK581183D0 DK581183D0 (da) 1983-12-16
DK581183A true DK581183A (da) 1984-06-18

Family

ID=6180952

Family Applications (1)

Application Number Title Priority Date Filing Date
DK581183A DK581183A (da) 1982-12-17 1983-12-16 2-azabicyclo(2.2.1)heptan-derivater, fremgangsmaader til deres fremstilling, midler indeholdende disse derivater og deres anvendelse, samt 2-azabicyclo(2.2.1)heptan-derivater som mellemprodukter samt fremgangsmaader til deres fremstilling

Country Status (10)

Country Link
EP (1) EP0113880A3 (da)
JP (1) JPS59130268A (da)
KR (1) KR840006971A (da)
AU (1) AU2249583A (da)
DE (1) DE3246757A1 (da)
DK (1) DK581183A (da)
ES (2) ES528066A0 (da)
GR (1) GR79480B (da)
PT (1) PT77825B (da)
ZA (1) ZA839347B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3303344A1 (de) 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3839127A1 (de) * 1988-11-19 1990-05-23 Hoechst Ag Pyrrolidon-2-carbonsaeure-derivate mit psychotroper wirkung
DD284030A5 (de) 1988-11-24 1990-10-31 Hoechst Ag,De Verfahren zur herstellung von peptiden mit bradykinin-antagonistischer wirkung
FR2655989B1 (fr) * 1989-12-20 1992-02-28 Adir Nouveaux derives d'amino-acides substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US6121280A (en) * 1998-03-24 2000-09-19 Pfizer Inc. Azabicyclic rotomase inhibitors
RU2712097C1 (ru) * 2018-09-28 2020-01-24 Общество с ограниченной ответственностью "Необиотек" Ингибитор дипептидилпептидазы-4 для лечения сахарного диабета 2-го типа, соединения (варианты)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492381A1 (fr) * 1980-10-21 1982-04-23 Science Union & Cie Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme

Also Published As

Publication number Publication date
EP0113880A3 (en) 1984-09-26
AU2249583A (en) 1984-06-21
GR79480B (da) 1984-10-30
ES8501401A1 (es) 1984-11-16
EP0113880A2 (de) 1984-07-25
ZA839347B (en) 1984-08-29
KR840006971A (ko) 1984-12-07
DE3246757A1 (de) 1984-06-20
PT77825A (de) 1984-01-01
JPS59130268A (ja) 1984-07-26
PT77825B (de) 1986-05-27
ES530388A0 (es) 1984-11-01
DK581183D0 (da) 1983-12-16
ES528066A0 (es) 1984-11-16
ES8500946A1 (es) 1984-11-01

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