DK1274399T3 - Liposomer indeholdende en indesluttet forbindelse i overmættet oplösning - Google Patents

Liposomer indeholdende en indesluttet forbindelse i overmættet oplösning

Info

Publication number
DK1274399T3
DK1274399T3 DK01906803T DK01906803T DK1274399T3 DK 1274399 T3 DK1274399 T3 DK 1274399T3 DK 01906803 T DK01906803 T DK 01906803T DK 01906803 T DK01906803 T DK 01906803T DK 1274399 T3 DK1274399 T3 DK 1274399T3
Authority
DK
Denmark
Prior art keywords
supersaturated solution
liposomes containing
encapsulated compound
compound
encapsulated
Prior art date
Application number
DK01906803T
Other languages
Danish (da)
English (en)
Inventor
Danilo D Lasic
Robert M Abra
Yechezkel Barenholz
Tal Peleg-Schulman
Original Assignee
Alza Corp
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp, Yissum Res Dev Co filed Critical Alza Corp
Application granted granted Critical
Publication of DK1274399T3 publication Critical patent/DK1274399T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK01906803T 2000-01-28 2001-01-26 Liposomer indeholdende en indesluttet forbindelse i overmættet oplösning DK1274399T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17865000P 2000-01-28 2000-01-28
PCT/US2001/003063 WO2001054666A1 (en) 2000-01-28 2001-01-26 Liposomes containing an entrapped compound in supersaturated solution

Publications (1)

Publication Number Publication Date
DK1274399T3 true DK1274399T3 (da) 2005-08-08

Family

ID=22653355

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01906803T DK1274399T3 (da) 2000-01-28 2001-01-26 Liposomer indeholdende en indesluttet forbindelse i overmættet oplösning

Country Status (19)

Country Link
US (2) US20010033861A1 (de)
EP (1) EP1274399B1 (de)
JP (1) JP2003521366A (de)
KR (2) KR100782891B1 (de)
CN (1) CN1236760C (de)
AT (1) ATE292957T1 (de)
AU (2) AU2001234670B2 (de)
CA (1) CA2398514A1 (de)
DE (1) DE60110057T2 (de)
DK (1) DK1274399T3 (de)
ES (1) ES2236181T3 (de)
HU (1) HUP0400628A3 (de)
IL (2) IL150483A0 (de)
MX (1) MXPA02007320A (de)
NO (1) NO20023139L (de)
NZ (1) NZ519856A (de)
PT (1) PT1274399E (de)
WO (1) WO2001054666A1 (de)
ZA (1) ZA200205468B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002336867A1 (en) * 2001-11-02 2003-05-12 Qlt Inc. Micelle compositions containing pegylated phospholipids and a photosensitizer
JP2005530704A (ja) * 2002-03-05 2005-10-13 トランセイブ, インク. 細胞内感染を予防及び治療するための吸入システム
US20050058734A1 (en) * 2002-12-18 2005-03-17 Algorx Administration of capsaicinoids
ES2562025T3 (es) * 2002-12-18 2016-03-02 Centrexion Therapeutics Corporation Administración de capsaicinoides para el tratamiento de la artrosis
US8980310B2 (en) * 2002-12-31 2015-03-17 Bharat Serums and Vaccines, Ltd. Non-pegylated long-circulating liposomes
KR20060015534A (ko) 2003-04-25 2006-02-17 더 펜 스테이트 리서치 파운데이션 성장 억제, 지질 유래된 생활성 화합물의 전신 전달을 위한방법 및 시스템
WO2008072584A1 (ja) * 2006-12-08 2008-06-19 Katayama Chemical Industries Co., Ltd. アンミン白金錯体を高濃度で内包するリポソームおよびその製造方法
US8158682B2 (en) * 2008-09-12 2012-04-17 Vallinex, Inc. Instillation administration of capsaicinoids for the treatment of pain
JP5983608B2 (ja) * 2011-07-15 2016-09-06 コニカミノルタ株式会社 溶解助剤を利用したリポソーム含有製剤およびその製造方法
WO2013070872A1 (en) * 2011-11-08 2013-05-16 The Board Of Trustees Of The University Of Arkansas Methods and compositions for x-ray induced release from ph sensitive liposomes
CN104203216A (zh) 2012-02-17 2014-12-10 效思因公司 热敏纳米颗粒制剂及其制备方法
EP2968142A1 (de) * 2013-03-13 2016-01-20 Mallinckrodt LLC Liposomale cisplatin-zusammensetzungen zur krebstherapie
US20160120806A1 (en) * 2014-04-08 2016-05-05 Aradigm Corporation Nanocrystals formed in a microenvironment
CA2943201A1 (en) * 2014-04-08 2015-10-15 Aradigm Corporation Liposomes that form drug nanocrystals after freeze-thaw
RU2016143590A (ru) 2014-04-08 2018-05-11 Арадайм Корпорейшн Липосомальные композиции ципрофлоксацина, обладающие активностью против нетуберкулезных микробактерий
WO2015166081A1 (en) 2014-04-30 2015-11-05 Encapson B.V. Medical devices with non-uniform coatings for enhanced echogenicity
CN108289845A (zh) * 2015-09-14 2018-07-17 维吉思康科技公司 皮下、舌下和口服治疗用空间稳定载体、用于治疗哺乳动物的组合物和方法
DE102017210700A1 (de) * 2017-06-26 2018-12-27 Robert Bosch Gmbh Verfahren zum automatisierten Quantifizieren eines Analyten sowie NMR-Messgerät zur Durchführung des Verfahrens
US10925831B2 (en) * 2017-08-28 2021-02-23 Wake Forest University Liposomal formulations of platinum-acridine anticancer agents and methods thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0177223B1 (de) 1984-09-24 1990-02-28 Michael Mezei Mehrphasige pharmazeutische Zusammensetzung
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
JP3199728B2 (ja) * 1990-04-18 2001-08-20 武田薬品工業株式会社 リポソーム製剤
EP0551169A1 (de) * 1992-01-10 1993-07-14 Takeda Chemical Industries, Ltd. Liposomzusammensetzung und Verfahren
US5395619A (en) 1993-03-03 1995-03-07 Liposome Technology, Inc. Lipid-polymer conjugates and liposomes
JP3464679B2 (ja) * 1996-08-21 2003-11-10 チルドレンズ・ホスピタル・メディカル・センター スキンライトニング組成物
EP0929293B1 (de) * 1996-08-23 2003-10-22 Sequus Pharmaceuticals, Inc. Liposome enthaltend cisplatin
TW520297B (en) 1996-10-11 2003-02-11 Sequus Pharm Inc Fusogenic liposome composition and method
AU4990397A (en) * 1996-10-22 1998-05-15 Dmitri Kirpotin Compound-loaded liposomes and methods for their preparation
WO2001025223A1 (en) * 1999-10-06 2001-04-12 The Research Foundation Of State University Of New York Stabilization of taxane-containing dispersed systems
CA2398182C (en) * 2000-01-31 2007-03-13 Pfizer Products Inc. Nicotinamide benzofused-heterocyclyl derivatives useful as selective inhibitors of pde4 isozymes

Also Published As

Publication number Publication date
AU2001234670B2 (en) 2005-05-19
PT1274399E (pt) 2005-07-29
US8062662B2 (en) 2011-11-22
EP1274399B1 (de) 2005-04-13
IL150483A (en) 2008-07-08
IL150483A0 (en) 2002-12-01
DE60110057T2 (de) 2005-09-08
EP1274399A1 (de) 2003-01-15
WO2001054666A1 (en) 2001-08-02
US20060159739A1 (en) 2006-07-20
NZ519856A (en) 2004-03-26
CN1236760C (zh) 2006-01-18
ES2236181T3 (es) 2005-07-16
KR100782891B1 (ko) 2007-12-06
MXPA02007320A (es) 2004-07-30
HUP0400628A2 (hu) 2004-06-28
KR20030011767A (ko) 2003-02-11
CN1396822A (zh) 2003-02-12
ZA200205468B (en) 2004-09-29
NO20023139D0 (no) 2002-06-28
JP2003521366A (ja) 2003-07-15
CA2398514A1 (en) 2001-08-02
HUP0400628A3 (en) 2006-07-28
DE60110057D1 (de) 2005-05-19
AU3467001A (en) 2001-08-07
NO20023139L (no) 2002-09-23
US20010033861A1 (en) 2001-10-25
ATE292957T1 (de) 2005-04-15
KR20070089761A (ko) 2007-08-31

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