ATE292957T1 - Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung - Google Patents

Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung

Info

Publication number
ATE292957T1
ATE292957T1 AT01906803T AT01906803T ATE292957T1 AT E292957 T1 ATE292957 T1 AT E292957T1 AT 01906803 T AT01906803 T AT 01906803T AT 01906803 T AT01906803 T AT 01906803T AT E292957 T1 ATE292957 T1 AT E292957T1
Authority
AT
Austria
Prior art keywords
supersaturated solution
liposomes containing
enclosed compound
compound
enclosed
Prior art date
Application number
AT01906803T
Other languages
English (en)
Inventor
Robert M Abra
Yechezkel Barenholz
Danilo D Lasic
Tal Peleg-Schulman
Original Assignee
Alza Corp
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp, Yissum Res Dev Co filed Critical Alza Corp
Application granted granted Critical
Publication of ATE292957T1 publication Critical patent/ATE292957T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
AT01906803T 2000-01-28 2001-01-26 Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung ATE292957T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17865000P 2000-01-28 2000-01-28
PCT/US2001/003063 WO2001054666A1 (en) 2000-01-28 2001-01-26 Liposomes containing an entrapped compound in supersaturated solution

Publications (1)

Publication Number Publication Date
ATE292957T1 true ATE292957T1 (de) 2005-04-15

Family

ID=22653355

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01906803T ATE292957T1 (de) 2000-01-28 2001-01-26 Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung

Country Status (19)

Country Link
US (2) US20010033861A1 (de)
EP (1) EP1274399B1 (de)
JP (1) JP2003521366A (de)
KR (2) KR20070089761A (de)
CN (1) CN1236760C (de)
AT (1) ATE292957T1 (de)
AU (2) AU2001234670B2 (de)
CA (1) CA2398514A1 (de)
DE (1) DE60110057T2 (de)
DK (1) DK1274399T3 (de)
ES (1) ES2236181T3 (de)
HU (1) HUP0400628A3 (de)
IL (2) IL150483A0 (de)
MX (1) MXPA02007320A (de)
NO (1) NO20023139L (de)
NZ (1) NZ519856A (de)
PT (1) PT1274399E (de)
WO (1) WO2001054666A1 (de)
ZA (1) ZA200205468B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2306785T3 (es) * 2001-11-02 2008-11-16 The Governors Of The University Of Alberta Composiciones de micelas que contienen fosfolipidos pegilados y un fotosensibilizador.
AU2003225689B2 (en) * 2002-03-05 2009-03-26 Transave, Inc. Methods for entrapment of bioactive agent in a liposome or lipid complex
JP2006513267A (ja) * 2002-12-18 2006-04-20 アルゴルクス ファーマスーティカルズ，インク カプサイシノイドの投与
WO2004056305A2 (en) * 2002-12-18 2004-07-08 Algorx Administration of capsaicinoids
US8980310B2 (en) * 2002-12-31 2015-03-17 Bharat Serums and Vaccines, Ltd. Non-pegylated long-circulating liposomes
KR20060015534A (ko) 2003-04-25 2006-02-17 더 펜 스테이트 리서치 파운데이션 성장 억제, 지질 유래된 생활성 화합물의 전신 전달을 위한방법 및 시스템
EP2090305A4 (de) * 2006-12-08 2012-12-26 Katayama Chemical Ind Co Ltd Liposom mit eingekapseltem ammin-platin-komplex von hoher konzentration und verfahren zur herstellung des liposoms
US8158682B2 (en) * 2008-09-12 2012-04-17 Vallinex, Inc. Instillation administration of capsaicinoids for the treatment of pain
JP5983608B2 (ja) * 2011-07-15 2016-09-06 コニカミノルタ株式会社 溶解助剤を利用したリポソーム含有製剤およびその製造方法
US9849087B2 (en) 2011-11-08 2017-12-26 The Board Of Trustees Of The University Of Arkansas Methods and compositions for X-ray induced release from pH sensitive liposomes
CN104203216A (zh) * 2012-02-17 2014-12-10 效思因公司 热敏纳米颗粒制剂及其制备方法
BR112015022415A2 (pt) * 2013-03-13 2017-07-18 Mallinckrodt Llc composições de cisplatina lipossômica para terapia contra câncer
CN106456551A (zh) * 2014-04-08 2017-02-22 阿拉迪姆公司 冻融后形成药物纳米晶体的脂质体
US20160120806A1 (en) * 2014-04-08 2016-05-05 Aradigm Corporation Nanocrystals formed in a microenvironment
EP3129004A4 (de) 2014-04-08 2017-11-15 Aradigm Corporation Liposomale ciprofloxacin-formulierungen mit aktivität gegen nicht-tuberkulose mykobakterien
PL3137126T3 (pl) 2014-04-30 2020-03-31 Encapson B.V. Urządzenia medyczne z niejednolitą powłoką w celu wzmocnienia echogeniczności
US20190046444A1 (en) * 2015-09-14 2019-02-14 Vgsk Techologies, Inc. A sterically stabilized carrier for subcutaneous, sublingual, and oral therapeutics, compositions and methods for treating a mammal
DE102017210700A1 (de) * 2017-06-26 2018-12-27 Robert Bosch Gmbh Verfahren zum automatisierten Quantifizieren eines Analyten sowie NMR-Messgerät zur Durchführung des Verfahrens
US10925831B2 (en) * 2017-08-28 2021-02-23 Wake Forest University Liposomal formulations of platinum-acridine anticancer agents and methods thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0177223B1 (de) 1984-09-24 1990-02-28 Michael Mezei Mehrphasige pharmazeutische Zusammensetzung
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
ATE119034T1 (de) * 1990-04-18 1995-03-15 Takeda Chemical Industries Ltd Liposomenzusammensetzung.
EP0551169A1 (de) * 1992-01-10 1993-07-14 Takeda Chemical Industries, Ltd. Liposomzusammensetzung und Verfahren
US5395619A (en) 1993-03-03 1995-03-07 Liposome Technology, Inc. Lipid-polymer conjugates and liposomes
DE69622599T2 (de) * 1996-08-21 2003-03-27 Childrens Hosp Medical Center Hautaufhellungszusammensetzungen
AU714992B2 (en) * 1996-08-23 2000-01-13 Alza Corporation Liposomes containing a cisplatin compound
TW520297B (en) 1996-10-11 2003-02-11 Sequus Pharm Inc Fusogenic liposome composition and method
EP0949906A4 (de) * 1996-10-22 2004-11-24 Hermes Biosciences Inc Mit wirkstoff beladene liposomen und deren herstellungsverfahren
US6348215B1 (en) * 1999-10-06 2002-02-19 The Research Foundation Of State University Of New York Stabilization of taxane-containing dispersed systems
BR0107964A (pt) * 2000-01-31 2002-10-29 Pfizer Prod Inc Derivados de nicotinamida benzofundida com heterociclica úteis como inibidores seletivos de isozimas pde4

Also Published As

Publication number Publication date
ZA200205468B (en) 2004-09-29
NO20023139L (no) 2002-09-23
CN1396822A (zh) 2003-02-12
HUP0400628A3 (en) 2006-07-28
EP1274399A1 (de) 2003-01-15
US20010033861A1 (en) 2001-10-25
JP2003521366A (ja) 2003-07-15
CN1236760C (zh) 2006-01-18
KR20030011767A (ko) 2003-02-11
KR100782891B1 (ko) 2007-12-06
WO2001054666A1 (en) 2001-08-02
NO20023139D0 (no) 2002-06-28
CA2398514A1 (en) 2001-08-02
DK1274399T3 (da) 2005-08-08
EP1274399B1 (de) 2005-04-13
DE60110057T2 (de) 2005-09-08
KR20070089761A (ko) 2007-08-31
AU3467001A (en) 2001-08-07
AU2001234670B2 (en) 2005-05-19
IL150483A0 (en) 2002-12-01
MXPA02007320A (es) 2004-07-30
PT1274399E (pt) 2005-07-29
US8062662B2 (en) 2011-11-22
IL150483A (en) 2008-07-08
ES2236181T3 (es) 2005-07-16
US20060159739A1 (en) 2006-07-20
DE60110057D1 (de) 2005-05-19
NZ519856A (en) 2004-03-26
HUP0400628A2 (hu) 2004-06-28

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