DK1272188T3 - Anvendelse af EGFR-tyrosinkinaseinhibitorer til behandling af brystcancer - Google Patents

Anvendelse af EGFR-tyrosinkinaseinhibitorer til behandling af brystcancer

Info

Publication number
DK1272188T3
DK1272188T3 DK00973002T DK00973002T DK1272188T3 DK 1272188 T3 DK1272188 T3 DK 1272188T3 DK 00973002 T DK00973002 T DK 00973002T DK 00973002 T DK00973002 T DK 00973002T DK 1272188 T3 DK1272188 T3 DK 1272188T3
Authority
DK
Denmark
Prior art keywords
breast cancer
tyrosine kinase
treatment
egfr tyrosine
kinase inhibitors
Prior art date
Application number
DK00973002T
Other languages
Danish (da)
English (en)
Inventor
Nigel James Bundred
Original Assignee
Univ Manchester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Manchester filed Critical Univ Manchester
Application granted granted Critical
Publication of DK1272188T3 publication Critical patent/DK1272188T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK00973002T 1999-11-02 2000-11-01 Anvendelse af EGFR-tyrosinkinaseinhibitorer til behandling af brystcancer DK1272188T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9925958.2A GB9925958D0 (en) 1999-11-02 1999-11-02 Therapeutic use
PCT/GB2000/004190 WO2001032155A2 (en) 1999-11-02 2000-11-01 Use of egfr tyrosine kinase inhibitors for treating breast cancer

Publications (1)

Publication Number Publication Date
DK1272188T3 true DK1272188T3 (da) 2007-01-29

Family

ID=10863835

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00973002T DK1272188T3 (da) 1999-11-02 2000-11-01 Anvendelse af EGFR-tyrosinkinaseinhibitorer til behandling af brystcancer

Country Status (21)

Country Link
US (1) US7553815B1 (ko)
EP (1) EP1272188B1 (ko)
JP (1) JP2003513035A (ko)
KR (1) KR100785359B1 (ko)
CN (1) CN1197577C (ko)
AT (1) ATE339957T1 (ko)
AU (1) AU779190B2 (ko)
BR (1) BR0015194A (ko)
CA (1) CA2389411C (ko)
CY (1) CY1106285T1 (ko)
DE (1) DE60030889T2 (ko)
DK (1) DK1272188T3 (ko)
ES (1) ES2275556T3 (ko)
GB (1) GB9925958D0 (ko)
IL (1) IL149176A0 (ko)
MX (1) MXPA02004272A (ko)
NO (1) NO323206B1 (ko)
NZ (1) NZ518696A (ko)
PT (1) PT1272188E (ko)
WO (1) WO2001032155A2 (ko)
ZA (1) ZA200203431B (ko)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL217410B1 (pl) 2000-05-19 2014-07-31 Genentech Inc Zastosowanie antagonisty ErbB, antagonista ErbB do zastosowania w metodzie leczenia raka i sposób identyfikacji pacjenta skłonnego do korzystnej odpowiedzi na antagonistę ErbB przy leczeniu raka
AU2002350105A1 (en) 2001-06-21 2003-01-08 Ariad Pharmaceuticals, Inc. Novel quinazolines and uses thereof
US6872715B2 (en) * 2001-08-06 2005-03-29 Kosan Biosciences, Inc. Benzoquinone ansamycins
AU2002349013A1 (en) * 2001-10-29 2003-05-12 Novartis Ag Use of 7h-pyrrolo(2,3-d)pyrimidine derivatives in the treatment of solid tumor diseases
EP1769795B1 (en) * 2001-12-03 2013-07-24 Bayer HealthCare LLC Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers
US7078409B2 (en) 2002-03-28 2006-07-18 Beta Pharma, Inc. Fused quinazoline derivatives useful as tyrosine kinase inhibitors
AU2003238871B2 (en) * 2002-06-05 2009-04-23 Cedars-Sinai Medical Center Method of treating cancer using kinase inhibitors
US20070059785A1 (en) * 2003-08-15 2007-03-15 Smithkline Beecham Corporation Biomarkers in cancer
SI1667992T1 (sl) 2003-09-19 2007-06-30 Astrazeneca Ab Kinazolinski derivati
WO2005039588A2 (en) * 2003-10-22 2005-05-06 Novartis Ag Methods for determining the risk of developing liver and lung toxicity
US7701341B2 (en) * 2004-09-01 2010-04-20 Microsoft Corporation Device service provider interface
CN102580084B (zh) 2005-01-21 2016-11-23 健泰科生物技术公司 Her抗体的固定剂量给药
SI1850874T1 (sl) 2005-02-23 2014-01-31 Genentech, Inc. Podaljšanje časa za napredovanje bolezni ali za preživetje pri pacientkah z rakom na jajčnikih ob uporabi pertuzumaba
CN101003514A (zh) 2006-01-20 2007-07-25 上海艾力斯医药科技有限公司 喹唑啉衍生物、其制备方法及用途
CN101415422B (zh) 2006-02-09 2012-11-07 第一三共株式会社 抗癌药用组合物
CN1899616A (zh) * 2006-07-20 2007-01-24 中国人民解放军军事医学科学院生物工程研究所 非受体酪氨酸激酶c－Abl特异性抑制剂的新用途
AU2008223069B2 (en) 2007-03-02 2012-12-13 F. Hoffmann-La Roche Ag Predicting response to a HER dimerisation inhibitor based on low HER3 expression
US9551033B2 (en) 2007-06-08 2017-01-24 Genentech, Inc. Gene expression markers of tumor resistance to HER2 inhibitor treatment
EP2171090B1 (en) 2007-06-08 2013-04-03 Genentech, Inc. Gene expression markers of tumor resistance to her2 inhibitor treatment
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
CA2972379A1 (en) 2009-03-11 2010-09-16 Ardea Biosciences, Inc. Pharmaceutical combinations comprising rdea119/bay 869766 for the treatment of specific cancers
MY152068A (en) 2009-03-20 2014-08-15 Genentech Inc Bispecific anti-her antibodies
WO2010136569A1 (en) 2009-05-29 2010-12-02 F. Hoffmann-La Roche Ag Modulators for her2 signaling in her2 expressing patients with gastric cancer
CN102892779B (zh) 2010-02-18 2016-12-21 基因泰克公司 神经调节蛋白拮抗剂及其在治疗癌症中的用途
WO2011146568A1 (en) 2010-05-19 2011-11-24 Genentech, Inc. Predicting response to a her inhibitor
EP2643353A1 (en) 2010-11-24 2013-10-02 Novartis AG Multispecific molecules
JP5766296B2 (ja) 2010-12-23 2015-08-19 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
CN103890007A (zh) 2011-08-17 2014-06-25 霍夫曼-拉罗奇有限公司 神经调节蛋白抗体及其用途
US9327023B2 (en) 2011-10-25 2016-05-03 The Regents Of The University Of Michigan HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells
SG11201402510TA (en) 2011-11-30 2014-06-27 Genentech Inc Erbb3 mutations in cancer
WO2013083810A1 (en) 2011-12-09 2013-06-13 F. Hoffmann-La Roche Ag Identification of non-responders to her2 inhibitors
JP2015514710A (ja) 2012-03-27 2015-05-21 ジェネンテック， インコーポレイテッド Ｈｅｒ３阻害剤に関する診断及び治療
MX363188B (es) 2012-11-30 2019-03-13 Hoffmann La Roche Identificación de pacientes con necesidad de coterapia del inhibidor de pd-l1.
EP3454863A1 (en) 2016-05-10 2019-03-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations therapies for the treatment of cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU661533B2 (en) 1992-01-20 1995-07-27 Astrazeneca Ab Quinazoline derivatives
US5795910A (en) * 1994-10-28 1998-08-18 Cor Therapeutics, Inc. Method and compositions for inhibiting protein kinases
PT817775E (pt) * 1995-03-30 2002-01-30 Pfizer Derivados de quinazolina
GB9508538D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivatives
GB9508565D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quiazoline derivative
MX9709867A (es) * 1995-06-07 1998-03-31 Pfizer Derivados de pirimidina condensados con un anillo heterociclico, composiciones que contienen los mismos, y uso de los mismos.
PT836605E (pt) * 1995-07-06 2002-07-31 Novartis Ag Pirrolopirimidinas e processos para a sua preparacao
PL348634A1 (en) * 1998-05-15 2002-06-03 Imclone Systems Inc Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases
CN101512597B (zh) 2006-08-28 2013-02-06 Tp视觉控股有限公司 图像增强方法和设备

Also Published As

Publication number Publication date
WO2001032155A2 (en) 2001-05-10
ES2275556T3 (es) 2007-06-16
NO323206B1 (no) 2007-01-22
DE60030889D1 (de) 2006-11-02
NO20022065D0 (no) 2002-04-30
IL149176A0 (en) 2002-11-10
EP1272188B1 (en) 2006-09-20
WO2001032155A3 (en) 2002-05-10
NZ518696A (en) 2004-12-24
PT1272188E (pt) 2007-01-31
GB9925958D0 (en) 1999-12-29
JP2003513035A (ja) 2003-04-08
BR0015194A (pt) 2002-06-18
CA2389411A1 (en) 2001-05-10
CN1197577C (zh) 2005-04-20
ZA200203431B (en) 2003-02-26
MXPA02004272A (es) 2003-08-20
US7553815B1 (en) 2009-06-30
KR100785359B1 (ko) 2007-12-18
AU1155901A (en) 2001-05-14
CN1387437A (zh) 2002-12-25
KR20020064306A (ko) 2002-08-07
DE60030889T2 (de) 2007-04-05
ATE339957T1 (de) 2006-10-15
AU779190B2 (en) 2005-01-13
NO20022065L (no) 2002-06-24
EP1272188A2 (en) 2003-01-08
CY1106285T1 (el) 2011-10-12
CA2389411C (en) 2009-09-01

Similar Documents

Publication Publication Date Title
DK1272188T3 (da) Anvendelse af EGFR-tyrosinkinaseinhibitorer til behandling af brystcancer
NZ515567A (en) Method for treating chronic pain using MEK inhibitors
NO20060398L (no) Anvendelse av en kombinasjon av en epidermal vekstfaktor reseptor kinase inhibitor og cytotoksiske midler for behandling og hemming av kreft
DK1255537T3 (da) Farnesylproteintransferasehæmmere til behandling af brystcancer
IL154949A0 (en) Imidazole derivatives as raf kinase inhibitors
MY138059A (en) Use of ikb-kinase inhibitors in pain therapy
DK1373215T3 (da) Gelanamycinderivater egnet til behandling af cancer
DE60332433D1 (de) Azolylaminoazine als proteinkinasehemmer
EA200300906A1 (ru) Новые спиротрициклические производные и их применение в качестве ингибиторов фосфодиэстеразы-7
TNSN04015A1 (en) Combination therapy for the treatment of cancer
ATE410155T1 (de) Verwendung von cyclin-d1-hemmern zur brustkrebsbehandlung
MX2007006927A (es) Combinacion de inhibidor de tirosina cinasa y her-2/neu para terapia de cancer.
CY1106289T1 (el) Χρηση αναστολεων υποδοχεος προγεστepονης για τη θepαπευτικη αντιμετωπιση του καρκινου του μαστου που ειναι ανθεκτικος σε στepοειδη
HK1080733A1 (en) Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, a cox-2 inhibitor and a taxol
TR200101693T2 (tr) Lemfotoksin (LT) sentezlenme yolunun inhibitörleri kullanılarak foliküler lemfomaların tedavisi.
DE60111515D1 (de) Kombinationstherapie mit keratinozyten-wachstumfaktor und ein epidermis-wachstumfaktor inhibitor
EA200200853A1 (ru) Применение 2-метилтиазолидин-3,3-дикарбоновой кислоты (2-мтдк) и/или ее физиологически совместимых солей для лечения и/или предупреждения рака
GEP201606538B (en) Preoperative treatment of post operative pain
NO20024545L (no) Fremgangsmåte for behandling av kongestiv hjertefeil
MXPA03010451A (es) Nuevos metodos para el tratamiento y prevencion del dolor.
UA67528A (en) Method for surgical treatment of thyroid cancer
EA200600987A1 (ru) Применение сирамезина в лечении злокачественных опухолей
ECSP003651A (es) Nuevos compuestos espiroheterociclicos utiles como inhibidores reversibles de cisteina-proteasas