DK1259509T3 - Fremgangsmåde til fremstilling af 6-methyl-2-(4-methylphenyl)-imidazol[1,2-a]pyridin-3-(N,N-dimethylacetamid) og mellemprodukter - Google Patents
Fremgangsmåde til fremstilling af 6-methyl-2-(4-methylphenyl)-imidazol[1,2-a]pyridin-3-(N,N-dimethylacetamid) og mellemprodukterInfo
- Publication number
- DK1259509T3 DK1259509T3 DK00981505T DK00981505T DK1259509T3 DK 1259509 T3 DK1259509 T3 DK 1259509T3 DK 00981505 T DK00981505 T DK 00981505T DK 00981505 T DK00981505 T DK 00981505T DK 1259509 T3 DK1259509 T3 DK 1259509T3
- Authority
- DK
- Denmark
- Prior art keywords
- methyl
- lower alkyl
- formula
- preparation
- phenyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000543 intermediate Substances 0.000 title abstract 2
- IGJYZHOQYHTURH-UHFFFAOYSA-N 2-(2,4-dimethylphenyl)-1h-imidazole Chemical compound CC1=CC(C)=CC=C1C1=NC=CN1 IGJYZHOQYHTURH-UHFFFAOYSA-N 0.000 title 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000000010 aprotic solvent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9904379A HU227358B1 (en) | 1999-11-22 | 1999-11-22 | Novel process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidyne-3-(n,n-dimethyl-acetamide) |
| HU9904377A HUP9904377A2 (en) | 1999-11-22 | 1999-11-22 | 6-methyl-2-(4-methyl-phenyl)-imidazole-[1,2-a]pyrimidine-3-acetic acid-esters and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1259509T3 true DK1259509T3 (da) | 2006-01-16 |
Family
ID=90000034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00981505T DK1259509T3 (da) | 1999-11-22 | 2000-11-22 | Fremgangsmåde til fremstilling af 6-methyl-2-(4-methylphenyl)-imidazol[1,2-a]pyridin-3-(N,N-dimethylacetamid) og mellemprodukter |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1259509B1 (da) |
| JP (1) | JP2003518016A (da) |
| KR (1) | KR100656636B1 (da) |
| CN (1) | CN1227252C (da) |
| AT (1) | ATE304540T1 (da) |
| AU (1) | AU1873901A (da) |
| CZ (1) | CZ300711B6 (da) |
| DE (1) | DE60022684T2 (da) |
| DK (1) | DK1259509T3 (da) |
| ES (1) | ES2248154T3 (da) |
| HR (1) | HRP20020471B1 (da) |
| PL (1) | PL354366A1 (da) |
| RU (1) | RU2254334C2 (da) |
| SK (1) | SK7122002A3 (da) |
| WO (1) | WO2001038327A2 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2509561A1 (en) | 2002-12-18 | 2004-07-15 | Mallinckrodt Inc. | Synthesis of heteroaryl acetamides |
| WO2004087703A1 (en) * | 2003-03-12 | 2004-10-14 | Sun Pharmaceutical Industries Limited | Process for the preparation of n,n,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide |
| SI1888294T1 (sl) | 2005-05-26 | 2014-08-29 | Alfa Laval Corporate Ab | Postopek trdega spajkanja izdelkov in nerjavečega jekla |
| US20080293946A1 (en) * | 2005-10-03 | 2008-11-27 | Cheng Brian K | Process for Preparing Zolpidem Hemitartrate and Tartrate Polymorphs |
| KR101008674B1 (ko) * | 2008-01-25 | 2011-01-18 | 주식회사 이화창 | 컨테이너 및 그 컨테이너를 구비한 두피 마사지기 |
| CN103360387B (zh) * | 2012-03-28 | 2016-12-14 | 江苏豪森药业集团有限公司 | 一种制备化合物唑吡坦的方法 |
| CN114105974A (zh) * | 2020-08-27 | 2022-03-01 | 鲁南制药集团股份有限公司 | 一种唑吡坦的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2151834B1 (es) * | 1998-08-06 | 2001-08-16 | Sint Quimica Sa | Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales. |
| ES2240074T3 (es) * | 1999-03-25 | 2005-10-16 | Synthon B.V. | Sales de zolpidem. |
-
2000
- 2000-11-22 CN CNB008173044A patent/CN1227252C/zh not_active Expired - Fee Related
- 2000-11-22 JP JP2001540090A patent/JP2003518016A/ja active Pending
- 2000-11-22 SK SK712-2002A patent/SK7122002A3/sk unknown
- 2000-11-22 RU RU2002116672/04A patent/RU2254334C2/ru not_active IP Right Cessation
- 2000-11-22 ES ES00981505T patent/ES2248154T3/es not_active Expired - Lifetime
- 2000-11-22 KR KR1020027006461A patent/KR100656636B1/ko not_active IP Right Cessation
- 2000-11-22 AT AT00981505T patent/ATE304540T1/de not_active IP Right Cessation
- 2000-11-22 AU AU18739/01A patent/AU1873901A/en not_active Abandoned
- 2000-11-22 DE DE60022684T patent/DE60022684T2/de not_active Expired - Fee Related
- 2000-11-22 CZ CZ20021713A patent/CZ300711B6/cs not_active IP Right Cessation
- 2000-11-22 DK DK00981505T patent/DK1259509T3/da active
- 2000-11-22 WO PCT/HU2000/000120 patent/WO2001038327A2/en active IP Right Grant
- 2000-11-22 EP EP00981505A patent/EP1259509B1/en not_active Expired - Lifetime
- 2000-11-22 PL PL00354366A patent/PL354366A1/xx not_active IP Right Cessation
-
2002
- 2002-05-28 HR HR20020471A patent/HRP20020471B1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20020052213A (ko) | 2002-07-02 |
| ES2248154T3 (es) | 2006-03-16 |
| ATE304540T1 (de) | 2005-09-15 |
| EP1259509B1 (en) | 2005-09-14 |
| KR100656636B1 (ko) | 2006-12-11 |
| WO2001038327A3 (en) | 2002-09-12 |
| HRP20020471A2 (en) | 2005-10-31 |
| CZ300711B6 (cs) | 2009-07-22 |
| CZ20021713A3 (cs) | 2002-08-14 |
| EP1259509A1 (en) | 2002-11-27 |
| CN1227252C (zh) | 2005-11-16 |
| DE60022684D1 (de) | 2005-10-20 |
| RU2254334C2 (ru) | 2005-06-20 |
| DE60022684T2 (de) | 2006-06-29 |
| CN1413212A (zh) | 2003-04-23 |
| PL354366A1 (en) | 2004-01-12 |
| AU1873901A (en) | 2001-06-04 |
| JP2003518016A (ja) | 2003-06-03 |
| HRP20020471B1 (en) | 2007-12-31 |
| SK7122002A3 (en) | 2002-10-08 |
| WO2001038327A2 (en) | 2001-05-31 |
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| HUP9904377A2 (en) | 6-methyl-2-(4-methyl-phenyl)-imidazole-[1,2-a]pyrimidine-3-acetic acid-esters and process for their preparation |