DK1255534T3 - Fremgangsmåde til fremstilling af mikrokugler, der indeholder kolloide systemer - Google Patents
Fremgangsmåde til fremstilling af mikrokugler, der indeholder kolloide systemerInfo
- Publication number
- DK1255534T3 DK1255534T3 DK01908459T DK01908459T DK1255534T3 DK 1255534 T3 DK1255534 T3 DK 1255534T3 DK 01908459 T DK01908459 T DK 01908459T DK 01908459 T DK01908459 T DK 01908459T DK 1255534 T3 DK1255534 T3 DK 1255534T3
- Authority
- DK
- Denmark
- Prior art keywords
- colloidal systems
- systems
- containing colloidal
- microspheres containing
- making microspheres
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medical Informatics (AREA)
- Dispersion Chemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Botany (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Colloid Chemistry (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/503,847 US6395302B1 (en) | 1996-11-19 | 2000-02-15 | Method for the preparation of microspheres which contain colloidal systems |
PCT/NL2001/000125 WO2001060339A2 (fr) | 2000-02-15 | 2001-02-15 | Preparation de microspheres contenant des systemes colloidaux |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1255534T3 true DK1255534T3 (da) | 2003-11-24 |
Family
ID=24003769
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01908459T DK1255534T3 (da) | 2000-02-15 | 2001-02-15 | Fremgangsmåde til fremstilling af mikrokugler, der indeholder kolloide systemer |
Country Status (9)
Country | Link |
---|---|
US (1) | US6395302B1 (fr) |
EP (1) | EP1255534B1 (fr) |
JP (1) | JP2003522781A (fr) |
AT (1) | ATE245971T1 (fr) |
AU (1) | AU2001236201A1 (fr) |
DE (1) | DE60100542T2 (fr) |
DK (1) | DK1255534T3 (fr) |
ES (1) | ES2204837T3 (fr) |
WO (1) | WO2001060339A2 (fr) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0901786B1 (fr) | 1997-08-11 | 2007-06-13 | Pfizer Products Inc. | Dispersions solides pharmaceutiques à biodisponibilité accrue |
EP1074248A1 (fr) * | 1999-07-08 | 2001-02-07 | Arnold Hilgers | Système de délivrance pour marériaux biologiques |
US6458387B1 (en) * | 1999-10-18 | 2002-10-01 | Epic Therapeutics, Inc. | Sustained release microspheres |
US6805879B2 (en) * | 2000-06-23 | 2004-10-19 | Biopharm Solutions Inc. | Stable polymer aqueous/aqueous emulsion system and uses thereof |
US6998393B2 (en) * | 2000-06-23 | 2006-02-14 | Biopharm Solutions, Inc. | Aquespheres, their preparation and uses thereof |
ES2326209T3 (es) | 2000-10-27 | 2009-10-05 | Baxter Healthcare S.A. | Produccion de microesferas. |
US6531444B1 (en) | 2000-11-09 | 2003-03-11 | Salvona, Llc | Controlled delivery system for fabric care products |
US7713942B2 (en) * | 2001-04-04 | 2010-05-11 | Nordic Vaccine Technology A/S | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides |
US20040126900A1 (en) * | 2001-04-13 | 2004-07-01 | Barry Stephen E | High affinity peptide- containing nanoparticles |
ES2307779T3 (es) * | 2001-08-16 | 2008-12-01 | Baxter International Inc. | Formulaciones de microparticulas a base de propelentes. |
US20080026068A1 (en) * | 2001-08-16 | 2008-01-31 | Baxter Healthcare S.A. | Pulmonary delivery of spherical insulin microparticles |
US7053034B2 (en) * | 2002-04-10 | 2006-05-30 | Salvona, Llc | Targeted controlled delivery compositions activated by changes in pH or salt concentration |
US6740631B2 (en) * | 2002-04-26 | 2004-05-25 | Adi Shefer | Multi component controlled delivery system for fabric care products |
US6825161B2 (en) * | 2002-04-26 | 2004-11-30 | Salvona Llc | Multi component controlled delivery system for soap bars |
US7208460B2 (en) * | 2002-04-26 | 2007-04-24 | Salvona Ip, Llc | Multi component controlled delivery system for soap bars |
GB2399084B (en) * | 2002-07-30 | 2007-01-31 | Univ Liverpool | Porous beads and method of production thereof |
WO2004078196A1 (fr) * | 2003-03-04 | 2004-09-16 | The Technology Development Company Ltd. | Composition d'insuline a administration orale et ses procedes de production et d'utilisation. |
US20070092452A1 (en) * | 2003-07-18 | 2007-04-26 | Julia Rashba-Step | Methods for fabrication, uses, compositions of inhalable spherical particles |
US20050142205A1 (en) * | 2003-07-18 | 2005-06-30 | Julia Rashba-Step | Methods for encapsulating small spherical particles prepared by controlled phase separation |
CN1826170B (zh) * | 2003-07-18 | 2010-12-08 | 巴克斯特国际公司 | 通过受控相分离制备的小球形颗粒的制造方法、其用途和成分 |
JP2007508240A (ja) * | 2003-07-22 | 2007-04-05 | バクスター・インターナショナル・インコーポレイテッド | 低分子量有機分子の小球状粒子ならびにその調製方法および使用方法 |
EP1576952A1 (fr) * | 2004-03-18 | 2005-09-21 | OctoPlus Technologies B.V. | Microsphères d'hydrogel avec un profil amélioré de libération |
EP1758558B1 (fr) * | 2004-05-12 | 2013-10-16 | Baxter International Inc. | Administration de microspheres d'oligonucleotides antisens pour induire une tolerance de cellules dendritiques pour le traitement du diabete de type 1 insulino-dependant |
AU2005244840C1 (en) | 2004-05-12 | 2012-05-10 | Baxter Healthcare S.A. | Microspheres comprising protein and showing injectability at high concentrations of said agent |
US8728525B2 (en) * | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
DE602005009954D1 (de) * | 2004-05-12 | 2008-11-06 | Baxter Int | Nukleinsäure-mikrokügelchen, ihre herstellung und abgabe |
EP1595534A1 (fr) | 2004-05-13 | 2005-11-16 | Universiteit Utrecht Holding B.V. | Gel composant des polymeres charges |
US20060034891A1 (en) * | 2004-08-12 | 2006-02-16 | Laurie Lawin | Biodegradable controlled release bioactive agent delivery device |
EP1885335A1 (fr) * | 2005-04-27 | 2008-02-13 | BAXTER INTERNATIONAL INC. (a Delaware corporation) | Microparticules a surface modifiee et procedes de formation et d'utilisation associes |
US20090099031A1 (en) * | 2005-09-27 | 2009-04-16 | Stemmer Willem P | Genetic package and uses thereof |
EP1929073A4 (fr) * | 2005-09-27 | 2010-03-10 | Amunix Inc | Produits pharmaceutiques proteiques et utilisations de ceux-ci |
US7855279B2 (en) * | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
US7846445B2 (en) * | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
JP5738516B2 (ja) | 2005-12-30 | 2015-06-24 | ゼンサン (シャンハイ) サイエンス アンド テクノロジー リミテッド | 心機能改善のためのニューレグリンの徐放 |
US20070281031A1 (en) * | 2006-06-01 | 2007-12-06 | Guohan Yang | Microparticles and methods for production thereof |
EP2037882B1 (fr) * | 2006-06-28 | 2014-12-10 | SurModics, Inc. | Matrice dégradable et matrice non dégradable en association pour la libération d'un agent actif |
MX2009001226A (es) | 2006-08-04 | 2009-03-20 | Baxter Int | Composicion basada en microesferas para prevenir y/o revertir la diabetes autoinmune de nuevo inicio. |
CN101652126B (zh) * | 2006-08-08 | 2013-07-17 | 得克萨斯大学体系董事会 | 活性试剂的多级递送 |
CA2600220C (fr) * | 2006-09-07 | 2014-12-09 | Canadian Blood Services | Particules lipidiques reticulees en surface et methodes de production et utilisations connexes |
MX2009003661A (es) * | 2006-10-06 | 2009-04-22 | Baxter Int | Microcapsulas que contienen microparticulas modificadas en la superficie y metodos para formar y utilizar las mismas. |
EP1972324A1 (fr) * | 2007-03-21 | 2008-09-24 | Cognis IP Management GmbH | Liposomes encapsulés |
NL1033621C2 (nl) * | 2007-03-30 | 2008-10-06 | Friesland Brands Bv | Encapsuleren met behulp van een dubbele suspensie. |
US8101274B2 (en) * | 2007-06-11 | 2012-01-24 | Spedden Richard H | Solid state membranes with surface-embedded glycosylated amphiphilic molecules and micelles formed therefrom |
JP2010536341A (ja) * | 2007-08-15 | 2010-12-02 | アムニクス, インコーポレイテッド | 生物学的に活性なポリペプチドの特性を改変するための組成物および方法 |
WO2009032266A2 (fr) * | 2007-09-04 | 2009-03-12 | University Of Florida | Dispersions de microparticules et de microgels dans des hydrogels pour la libération de médicaments |
US8530244B2 (en) * | 2007-10-02 | 2013-09-10 | Terapia Celular, L'N, Inc. | Methods and materials for amplification of a signal in an immunoassay |
KR20110042107A (ko) | 2008-08-07 | 2011-04-22 | 바이오엑티브 써지컬, 아이엔씨. | 의료 장치 및 이식물을 위한 줄기 세포 포획 및 고정화 코팅 |
US20100047292A1 (en) * | 2008-08-20 | 2010-02-25 | Baxter International Inc. | Methods of processing microparticles and compositions produced thereby |
US8367427B2 (en) * | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
US8323615B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
US8323685B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
AU2009302042A1 (en) | 2008-10-07 | 2010-04-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Liposomal systems comprising sphingomyelin |
EP2393828B1 (fr) | 2009-02-03 | 2016-10-12 | Amunix Operating Inc. | Polypeptides recombinants étendus et compositions les comprenant |
WO2010102066A1 (fr) | 2009-03-05 | 2010-09-10 | Bend Research, Inc. | Poudre de polymère de dextrane destinée à l'administration de produits pharmaceutiques par inhalation |
US9724664B2 (en) | 2009-03-27 | 2017-08-08 | Bend Research, Inc. | Spray-drying process |
WO2011028229A1 (fr) | 2009-08-24 | 2011-03-10 | Amunix Operating Inc. | Compositions de facteur ix de coagulation et leurs procédés de fabrication et d'utilisation |
JP2013509422A (ja) | 2009-10-30 | 2013-03-14 | シーエヌエス セラピューティクス,インク. | 改良されたニュールツリン分子 |
SI4005592T1 (sl) | 2010-07-06 | 2023-03-31 | Glaxosmithkline Biologicals S.A. | Virionom podobni dostavni delci za samopodvojene molekule RNA |
SI3243526T1 (sl) | 2010-07-06 | 2020-02-28 | Glaxosmithkline Biologicals S.A. | Dostava RNA za sprožitev večih imunskih poti |
BR112013000244A2 (pt) | 2010-07-06 | 2016-05-17 | Novartis Ag | lipossomas com lipídeos apresentando pka vantajoso para administração de rna |
EP2591114B1 (fr) | 2010-07-06 | 2016-06-08 | GlaxoSmithKline Biologicals SA | Immunisation de grands mammifères à l'aide de faibles doses d'arn |
ES2938866T3 (es) | 2010-08-31 | 2023-04-17 | Glaxosmithkline Biologicals Sa | Liposomas pegilados para la administración de ARN que codifica para inmunógeno |
PT2611530T (pt) | 2010-09-03 | 2019-05-09 | Bend Res Inc | Aparelho de secagem por pulverização e métodos de utilização do mesmo |
EP2611529B1 (fr) | 2010-09-03 | 2019-01-23 | Bend Research, Inc. | Procedede de séchage par pulvérisation |
US8815294B2 (en) | 2010-09-03 | 2014-08-26 | Bend Research, Inc. | Pharmaceutical compositions of dextran polymer derivatives and a carrier material |
WO2012040502A1 (fr) | 2010-09-24 | 2012-03-29 | Bend Research, Inc. | Procédé et appareil de séchage par pulvérisation à température élevée |
ES2716243T3 (es) | 2010-10-11 | 2019-06-11 | Glaxosmithkline Biologicals Sa | Plataformas de suministro de antígenos |
US9060938B2 (en) | 2011-05-10 | 2015-06-23 | Bend Research, Inc. | Pharmaceutical compositions of active agents and cationic dextran polymer derivatives |
EP3854413A1 (fr) | 2011-07-06 | 2021-07-28 | GlaxoSmithKline Biologicals SA | Compositions de combinaisons immunogènes et utilisations de celles-ci |
AU2012356239B2 (en) | 2011-11-04 | 2016-09-22 | Nitto Denko Corporation | Method of producing lipid nanoparticles for drug delivery |
HUE043537T2 (hu) | 2012-02-15 | 2019-08-28 | Bioverativ Therapeutics Inc | Rekombináns VIII faktor fehérjék |
RS63870B1 (sr) | 2012-02-15 | 2023-01-31 | Bioverativ Therapeutics Inc | Sastavi faktora viii i postupci za pravljenje i upotrebu istih |
US10548953B2 (en) | 2013-08-14 | 2020-02-04 | Bioverativ Therapeutics Inc. | Factor VIII-XTEN fusions and uses thereof |
CA2963871A1 (fr) * | 2014-10-08 | 2016-04-14 | Maamar ACHACHA | Formulation d'altrenogest et utilisations de celle-ci pour la synchronisation de l'strus chez des animaux |
EP3331608A4 (fr) | 2015-08-03 | 2019-05-01 | Bioverativ Therapeutics Inc. | Protéines de fusion du facteur xi et leurs méthodes de production et d'utilisation |
AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
ES2908479T3 (es) | 2015-08-26 | 2022-04-29 | Achillion Pharmaceuticals Inc | Compuestos para el tratamiento de trastornos inmunitarios e inflamatorios |
RU2018145364A (ru) | 2016-06-27 | 2020-07-28 | Ачиллион Фармасьютикалс, Инк. | Хиназолиновые и индольные соединения для лечения медицинских нарушений |
JP2021535112A (ja) | 2018-08-20 | 2021-12-16 | アキリオン ファーマシューティカルズ,インコーポレーテッド | 補体d因子の医学的障害の治療のための医薬化合物 |
EP3866773A4 (fr) | 2018-10-16 | 2022-10-26 | Georgia State University Research Foundation, Inc. | Promédicaments de monoxyde de carbone pour le traitement de troubles médicaux |
GB202000475D0 (en) * | 2020-01-13 | 2020-02-26 | Cambridge Entpr Ltd | A sensor |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4963367A (en) | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
EP0199362A3 (fr) * | 1985-04-26 | 1987-10-07 | Massachusetts Institute Of Technology | Système et dispositif pour la libération retardée et par à-coups de substances biologiquement actives |
US4921757A (en) * | 1985-04-26 | 1990-05-01 | Massachusetts Institute Of Technology | System for delayed and pulsed release of biologically active substances |
SE459005B (sv) * | 1985-07-12 | 1989-05-29 | Aake Rikard Lindahl | Saett att framstaella sfaeriska polymerpartiklar |
US5639441A (en) * | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
US5603955A (en) | 1994-07-18 | 1997-02-18 | University Of Cincinnati | Enhanced loading of solutes into polymer gels |
US5827707A (en) * | 1995-06-07 | 1998-10-27 | Neocrin Company | Method for manufacturing minimal volume capsules containing biological materials |
ES2222507T3 (es) * | 1996-11-19 | 2005-02-01 | Octoplus B.V. | Microesferas de liberacion controlada. |
EP0842657A1 (fr) * | 1996-11-19 | 1998-05-20 | OctoPlus B.V. | Microsphères pour la libération contrÔlée et procédés pour la préparation de telles microsphères |
-
2000
- 2000-02-15 US US09/503,847 patent/US6395302B1/en not_active Expired - Fee Related
-
2001
- 2001-02-15 WO PCT/NL2001/000125 patent/WO2001060339A2/fr active IP Right Grant
- 2001-02-15 DK DK01908459T patent/DK1255534T3/da active
- 2001-02-15 EP EP01908459A patent/EP1255534B1/fr not_active Expired - Lifetime
- 2001-02-15 AT AT01908459T patent/ATE245971T1/de not_active IP Right Cessation
- 2001-02-15 ES ES01908459T patent/ES2204837T3/es not_active Expired - Lifetime
- 2001-02-15 JP JP2001559437A patent/JP2003522781A/ja active Pending
- 2001-02-15 DE DE60100542T patent/DE60100542T2/de not_active Expired - Lifetime
- 2001-02-15 AU AU2001236201A patent/AU2001236201A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001060339A3 (fr) | 2001-12-06 |
JP2003522781A (ja) | 2003-07-29 |
ATE245971T1 (de) | 2003-08-15 |
DE60100542T2 (de) | 2004-06-09 |
AU2001236201A1 (en) | 2001-08-27 |
WO2001060339A2 (fr) | 2001-08-23 |
US6395302B1 (en) | 2002-05-28 |
ES2204837T3 (es) | 2004-05-01 |
EP1255534A2 (fr) | 2002-11-13 |
DE60100542D1 (de) | 2003-09-04 |
EP1255534B1 (fr) | 2003-07-30 |
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