AU2001236201A1 - Method for the preparation of microspheres which contain colloidal systems - Google Patents

Method for the preparation of microspheres which contain colloidal systems

Info

Publication number
AU2001236201A1
AU2001236201A1 AU2001236201A AU3620101A AU2001236201A1 AU 2001236201 A1 AU2001236201 A1 AU 2001236201A1 AU 2001236201 A AU2001236201 A AU 2001236201A AU 3620101 A AU3620101 A AU 3620101A AU 2001236201 A1 AU2001236201 A1 AU 2001236201A1
Authority
AU
Australia
Prior art keywords
microspheres
colloidal systems
preparation
systems
contain colloidal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001236201A
Inventor
Okke Franssen
Wilhelmus Everhardus Hennink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OctoPlus Technologies BV
Original Assignee
Octoplus BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octoplus BV filed Critical Octoplus BV
Publication of AU2001236201A1 publication Critical patent/AU2001236201A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery

Abstract

The invention relates to a method for the preparation of microencapsulated colloidal systems such as liposomes, i.e., microspheres which comprise colloidal systems. These microencapsulated colloidal systems can be used as controlled release systems for the delivery of active ingredients in in vivo and in vitro applications. A method is provided in which the colloidal systems are added to a phase which comprises a water soluble crosslinkable polymer followed by formation of microspheres.
AU2001236201A 2000-02-15 2001-02-15 Method for the preparation of microspheres which contain colloidal systems Abandoned AU2001236201A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09503847 2000-02-15
US09/503,847 US6395302B1 (en) 1996-11-19 2000-02-15 Method for the preparation of microspheres which contain colloidal systems
PCT/NL2001/000125 WO2001060339A2 (en) 2000-02-15 2001-02-15 Method for the preparation of microspheres which contain colloidal systems

Publications (1)

Publication Number Publication Date
AU2001236201A1 true AU2001236201A1 (en) 2001-08-27

Family

ID=24003769

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001236201A Abandoned AU2001236201A1 (en) 2000-02-15 2001-02-15 Method for the preparation of microspheres which contain colloidal systems

Country Status (9)

Country Link
US (1) US6395302B1 (en)
EP (1) EP1255534B1 (en)
JP (1) JP2003522781A (en)
AT (1) ATE245971T1 (en)
AU (1) AU2001236201A1 (en)
DE (1) DE60100542T2 (en)
DK (1) DK1255534T3 (en)
ES (1) ES2204837T3 (en)
WO (1) WO2001060339A2 (en)

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Also Published As

Publication number Publication date
ATE245971T1 (en) 2003-08-15
ES2204837T3 (en) 2004-05-01
EP1255534A2 (en) 2002-11-13
DE60100542D1 (en) 2003-09-04
DE60100542T2 (en) 2004-06-09
US6395302B1 (en) 2002-05-28
WO2001060339A3 (en) 2001-12-06
JP2003522781A (en) 2003-07-29
WO2001060339A2 (en) 2001-08-23
EP1255534B1 (en) 2003-07-30
DK1255534T3 (en) 2003-11-24

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