DK124281A - Fremgangsmaade til fremstilling af vinca-dimere og farmaceutissk acceptable syreadditionssalte deraf - Google Patents
Fremgangsmaade til fremstilling af vinca-dimere og farmaceutissk acceptable syreadditionssalte derafInfo
- Publication number
- DK124281A DK124281A DK124281A DK124281A DK124281A DK 124281 A DK124281 A DK 124281A DK 124281 A DK124281 A DK 124281A DK 124281 A DK124281 A DK 124281A DK 124281 A DK124281 A DK 124281A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- production
- acid addition
- addition salts
- acceptable acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/02—Ergot alkaloids of the cyclic peptide type
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/132,246 US4357334A (en) | 1980-03-20 | 1980-03-20 | Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK124281A true DK124281A (da) | 1981-09-21 |
Family
ID=22453135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK124281A DK124281A (da) | 1980-03-20 | 1981-03-19 | Fremgangsmaade til fremstilling af vinca-dimere og farmaceutissk acceptable syreadditionssalte deraf |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4357334A (ro) |
| EP (1) | EP0036762B1 (ro) |
| JP (1) | JPS56145293A (ro) |
| KR (1) | KR840002146B1 (ro) |
| AR (1) | AR228863A1 (ro) |
| AT (1) | ATE9761T1 (ro) |
| AU (1) | AU539564B2 (ro) |
| BG (1) | BG36200A3 (ro) |
| CA (1) | CA1159055A (ro) |
| DD (1) | DD157558A5 (ro) |
| DE (1) | DE3166544D1 (ro) |
| DK (1) | DK124281A (ro) |
| EG (1) | EG15247A (ro) |
| ES (2) | ES8206538A1 (ro) |
| FI (1) | FI810856L (ro) |
| GB (1) | GB2072184B (ro) |
| GR (1) | GR73870B (ro) |
| HU (1) | HU185247B (ro) |
| IE (1) | IE51034B1 (ro) |
| IL (1) | IL62378A (ro) |
| NZ (1) | NZ196511A (ro) |
| PH (1) | PH16213A (ro) |
| PL (1) | PL230226A1 (ro) |
| PT (1) | PT72695B (ro) |
| RO (2) | RO82171A (ro) |
| SU (2) | SU1017172A3 (ro) |
| YU (1) | YU66281A (ro) |
| ZA (1) | ZA811733B (ro) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR81790B (ro) * | 1983-04-29 | 1984-12-12 | Omnichem Sa | |
| HUT76925A (hu) * | 1995-04-04 | 1998-01-28 | MTA Enzimológiai Intézet | Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR204004A1 (es) | 1973-04-02 | 1975-11-12 | Lilly Co Eli | Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina |
| IL48685A (en) | 1975-01-09 | 1980-03-31 | Lilly Co Eli | Amides of vincadioline and vinblastine |
| GR69783B (ro) | 1976-09-08 | 1982-07-07 | Lilly Co Eli | |
| US4160767A (en) * | 1976-12-06 | 1979-07-10 | Eli Lilly And Company | Vinca alkaloid intermediates |
| USRE30561E (en) | 1976-12-06 | 1981-03-31 | Eli Lilly And Company | Vinca alkaloid intermediates |
| US4096148A (en) * | 1976-12-06 | 1978-06-20 | Eli Lilly And Company | Oxazolidinedione derivatives of Vinca alkaloids |
| US4191688A (en) * | 1977-08-08 | 1980-03-04 | Eli Lilly And Company | Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine |
| US4203898A (en) * | 1977-08-29 | 1980-05-20 | Eli Lilly And Company | Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids |
-
1980
- 1980-03-20 US US06/132,246 patent/US4357334A/en not_active Expired - Lifetime
-
1981
- 1981-03-16 PH PH25360A patent/PH16213A/en unknown
- 1981-03-16 CA CA000373113A patent/CA1159055A/en not_active Expired
- 1981-03-16 ZA ZA00811733A patent/ZA811733B/xx unknown
- 1981-03-16 NZ NZ196511A patent/NZ196511A/xx unknown
- 1981-03-16 YU YU00662/81A patent/YU66281A/xx unknown
- 1981-03-16 IL IL62378A patent/IL62378A/xx unknown
- 1981-03-16 GR GR64408A patent/GR73870B/el unknown
- 1981-03-17 AR AR284619A patent/AR228863A1/es active
- 1981-03-18 EG EG81148A patent/EG15247A/xx active
- 1981-03-18 ES ES500536A patent/ES8206538A1/es not_active Expired
- 1981-03-19 PT PT72695A patent/PT72695B/pt unknown
- 1981-03-19 AT AT81301186T patent/ATE9761T1/de not_active IP Right Cessation
- 1981-03-19 IE IE609/81A patent/IE51034B1/en unknown
- 1981-03-19 PL PL23022681A patent/PL230226A1/xx unknown
- 1981-03-19 EP EP81301186A patent/EP0036762B1/en not_active Expired
- 1981-03-19 GB GB8108644A patent/GB2072184B/en not_active Expired
- 1981-03-19 KR KR1019810000914A patent/KR840002146B1/ko active IP Right Grant
- 1981-03-19 RO RO81103759A patent/RO82171A/ro unknown
- 1981-03-19 HU HU81707A patent/HU185247B/hu unknown
- 1981-03-19 DK DK124281A patent/DK124281A/da not_active IP Right Cessation
- 1981-03-19 FI FI810856A patent/FI810856L/fi not_active Application Discontinuation
- 1981-03-19 RO RO110924A patent/RO85813B/ro unknown
- 1981-03-19 SU SU813259901A patent/SU1017172A3/ru active
- 1981-03-19 DE DE8181301186T patent/DE3166544D1/de not_active Expired
- 1981-03-20 JP JP4162781A patent/JPS56145293A/ja active Pending
- 1981-03-20 BG BG051306A patent/BG36200A3/xx unknown
- 1981-03-20 DD DD81228492A patent/DD157558A5/de unknown
- 1981-03-20 AU AU68581/81A patent/AU539564B2/en not_active Ceased
-
1982
- 1982-02-12 ES ES509581A patent/ES509581A0/es active Granted
- 1982-05-04 SU SU823430670A patent/SU1200851A3/ru active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |