DK124281A - Fremgangsmaade til fremstilling af vinca-dimere og farmaceutissk acceptable syreadditionssalte deraf - Google Patents

Fremgangsmaade til fremstilling af vinca-dimere og farmaceutissk acceptable syreadditionssalte deraf

Info

Publication number
DK124281A
DK124281A DK124281A DK124281A DK124281A DK 124281 A DK124281 A DK 124281A DK 124281 A DK124281 A DK 124281A DK 124281 A DK124281 A DK 124281A DK 124281 A DK124281 A DK 124281A
Authority
DK
Denmark
Prior art keywords
procedure
production
acid addition
addition salts
acceptable acid
Prior art date
Application number
DK124281A
Other languages
Danish (da)
English (en)
Inventor
J C Miller
G E Gutowski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK124281A publication Critical patent/DK124281A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02Ergot alkaloids of the cyclic peptide type
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK124281A 1980-03-20 1981-03-19 Fremgangsmaade til fremstilling af vinca-dimere og farmaceutissk acceptable syreadditionssalte deraf DK124281A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/132,246 US4357334A (en) 1980-03-20 1980-03-20 Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms

Publications (1)

Publication Number Publication Date
DK124281A true DK124281A (da) 1981-09-21

Family

ID=22453135

Family Applications (1)

Application Number Title Priority Date Filing Date
DK124281A DK124281A (da) 1980-03-20 1981-03-19 Fremgangsmaade til fremstilling af vinca-dimere og farmaceutissk acceptable syreadditionssalte deraf

Country Status (28)

Country Link
US (1) US4357334A (fi)
EP (1) EP0036762B1 (fi)
JP (1) JPS56145293A (fi)
KR (1) KR840002146B1 (fi)
AR (1) AR228863A1 (fi)
AT (1) ATE9761T1 (fi)
AU (1) AU539564B2 (fi)
BG (1) BG36200A3 (fi)
CA (1) CA1159055A (fi)
DD (1) DD157558A5 (fi)
DE (1) DE3166544D1 (fi)
DK (1) DK124281A (fi)
EG (1) EG15247A (fi)
ES (2) ES8206538A1 (fi)
FI (1) FI810856L (fi)
GB (1) GB2072184B (fi)
GR (1) GR73870B (fi)
HU (1) HU185247B (fi)
IE (1) IE51034B1 (fi)
IL (1) IL62378A (fi)
NZ (1) NZ196511A (fi)
PH (1) PH16213A (fi)
PL (1) PL230226A1 (fi)
PT (1) PT72695B (fi)
RO (2) RO82171A (fi)
SU (2) SU1017172A3 (fi)
YU (1) YU66281A (fi)
ZA (1) ZA811733B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR81790B (fi) * 1983-04-29 1984-12-12 Omnichem Sa
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (fi) 1976-09-08 1982-07-07 Lilly Co Eli
US4160767A (en) * 1976-12-06 1979-07-10 Eli Lilly And Company Vinca alkaloid intermediates
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
US4191688A (en) * 1977-08-08 1980-03-04 Eli Lilly And Company Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

Also Published As

Publication number Publication date
EG15247A (en) 1986-03-31
IL62378A0 (en) 1981-05-20
ES8302009A1 (es) 1982-12-16
ATE9761T1 (de) 1984-10-15
NZ196511A (en) 1983-09-30
GB2072184B (en) 1984-01-11
AR228863A1 (es) 1983-04-29
AU539564B2 (en) 1984-10-04
RO82171B (ro) 1983-06-30
EP0036762B1 (en) 1984-10-10
PH16213A (en) 1983-08-05
FI810856L (fi) 1981-09-21
IE810609L (en) 1981-09-20
KR840002146B1 (ko) 1984-11-23
ES509581A0 (es) 1982-12-16
ES500536A0 (es) 1982-08-16
GR73870B (fi) 1984-05-09
CA1159055A (en) 1983-12-20
JPS56145293A (en) 1981-11-11
AU6858181A (en) 1981-09-24
SU1017172A3 (ru) 1983-05-07
KR830005248A (ko) 1983-08-03
PT72695B (en) 1982-03-24
ES8206538A1 (es) 1982-08-16
SU1200851A3 (ru) 1985-12-23
US4357334A (en) 1982-11-02
ZA811733B (en) 1982-10-27
IL62378A (en) 1984-03-30
PT72695A (en) 1981-04-01
YU66281A (en) 1983-10-31
PL230226A1 (fi) 1982-03-15
GB2072184A (en) 1981-09-30
DD157558A5 (de) 1982-11-17
RO82171A (ro) 1983-07-07
RO85813B (ro) 1984-11-30
EP0036762A3 (en) 1981-10-07
DE3166544D1 (en) 1984-11-15
IE51034B1 (en) 1986-09-17
EP0036762A2 (en) 1981-09-30
HU185247B (en) 1984-12-28
RO85813A (ro) 1984-11-25
BG36200A3 (en) 1984-09-14

Similar Documents

Publication Publication Date Title
RO86825A (ro) Procedeu pentru prepararea unor acizi 7-amino-3-metil-substituit -dela 3-cefem-4-carbo0ilici
FI833641A0 (fi) Doseringsanordning foer medicin
DK160314C (da) Analogifremgangsmaade til fremstilling af bicycliske pyrimidin-5-on-derivater og farmaceutisk acceptable salte deraf
DK254688D0 (da) Fremgangsmaade til fremstilling af folininsyre
DK162444C (da) Analogifremgangsmaade til fremstilling af azabicyklooctancarboxylsyrer og farmaceutisk acceptable salte heraf
NO163869C (no) Fremgangsmaate for dehalogenering av kvartaere aminosyrehalogenider.
DK30083A (da) Diphosphonsyrederivater og fremgangsmaade til fremstilling deraf
DK157862C (da) Analogifremgangsmaade til fremstilling af imidazolylphenylamidiner eller farmaceutisk acceptable syreadditionssalte deraf
DK330582A (da) Herbicidt virksomme 5-amino-1-phenylpyrazol-4-carboxylsyrederivater og fremgangsmaade til fremstilling deraf
DK165355C (da) Fremgangsmaade til mikroindkapsling af laegemidler
DK32383D0 (da) Phosphinsyrederivater og fremgangsmade til fremstilling af disse
DK163917C (da) Gamma-substituerede beta-hydroxybutansyrederivater og fremgangsmaade til fremstilling heraf
DK108581A (da) 2-penem-3-carboxylsyre-derivater og fremgangsmaade til fremstiling heraf
DK34781A (da) Fremgangsmaade til fremstilling af phenylalkansyrederivater
DK163989C (da) Analogifremgangsmaade til fremstilling af beta-adrenergisk blokerende forbindelser og farmaceutisk acceptable salte deraf
DK280285D0 (da) Fremgangsmaade til fremstilling af ascorbinsyre
DK124281A (da) Fremgangsmaade til fremstilling af vinca-dimere og farmaceutissk acceptable syreadditionssalte deraf
DK281884D0 (da) Fremgangsmaade til fremstilling af 2-substituerede 2-penem-3-carboxylsyre-forbindelser og mellemprodukter herved
DK228381A (da) Fremgangsmaade til fremstilling af antidiarretiske farmaceutiske praeparater
DK382886A (da) Fremgangsmaade til fremstilling af hormonfaktorderivater
DK576881A (da) Fremgangsmaade til fremstilling af monsyreestere
DK489084A (da) Fremgangsmaade til udvinding af beta-elemonsyre og farmaceutisk praeparat indeholdende beta-elemonsyre
DK162769C (da) Fremgangsmaade til fremstilling af 2beta-chlormethyl-2alfa-methylpenam-3alfa-carboxylsyresulfon samt farmaceutisk acceptable salte og estere deraf
DK343481A (da) Substitueret ureidobenzylpenicillansyre og fremgangsmaade til fremstilling deraf
DK222981A (da) Fremgangsmaade til fremstilling af diacetoneketogulonsyre

Legal Events

Date Code Title Description
PBP Patent lapsed