DK1194161T3 - Stabile faktor VIII-sammensatninger - Google Patents

Stabile faktor VIII-sammensatninger

Info

Publication number
DK1194161T3
DK1194161T3 DK00948452T DK00948452T DK1194161T3 DK 1194161 T3 DK1194161 T3 DK 1194161T3 DK 00948452 T DK00948452 T DK 00948452T DK 00948452 T DK00948452 T DK 00948452T DK 1194161 T3 DK1194161 T3 DK 1194161T3
Authority
DK
Denmark
Prior art keywords
factor viii
stable factor
viii compositions
compositions
stable
Prior art date
Application number
DK00948452T
Other languages
English (en)
Inventor
Marianne Mikaelsson
Helena Sandberg
Original Assignee
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27354553&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1194161(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE9902685A external-priority patent/SE9902685D0/xx
Priority claimed from SE0001743A external-priority patent/SE0001743D0/xx
Application filed by Biovitrum Ab filed Critical Biovitrum Ab
Application granted granted Critical
Publication of DK1194161T3 publication Critical patent/DK1194161T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK00948452T 1999-07-13 2000-07-07 Stabile faktor VIII-sammensatninger DK1194161T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9902685A SE9902685D0 (sv) 1999-07-13 1999-07-13 Stable protein compositions
US14682899P 1999-08-02 1999-08-02
SE0001743A SE0001743D0 (sv) 2000-05-11 2000-05-11 Stable protein compositions II

Publications (1)

Publication Number Publication Date
DK1194161T3 true DK1194161T3 (da) 2006-02-13

Family

ID=27354553

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00948452T DK1194161T3 (da) 1999-07-13 2000-07-07 Stabile faktor VIII-sammensatninger

Country Status (14)

Country Link
US (1) US6599724B1 (da)
EP (1) EP1194161B1 (da)
JP (1) JP4674021B2 (da)
AR (1) AR024735A1 (da)
AT (1) ATE310533T1 (da)
AU (1) AU780415B2 (da)
CA (1) CA2378751C (da)
CY (1) CY1104986T1 (da)
DE (1) DE60024268T2 (da)
DK (1) DK1194161T3 (da)
ES (1) ES2252028T3 (da)
NO (1) NO330048B1 (da)
NZ (1) NZ516400A (da)
WO (1) WO2001003726A1 (da)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101683522B (zh) 1999-02-22 2013-05-01 巴克斯特国际有限公司 新的无白蛋白的因子ⅷ制剂
JP2005530683A (ja) * 2001-12-21 2005-10-13 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 第ｖｉｉ因子ポリペプチドの液体組成物
KR20040065278A (ko) * 2001-12-21 2004-07-21 노보 노르디스크 에이/에스 변경된 인자 ⅶ 폴리펩티드의 액체 조성물
GB0202633D0 (en) * 2002-02-05 2002-03-20 Delta Biotechnology Ltd Stabilization of protein preparations
GB0207092D0 (en) * 2002-03-26 2002-05-08 Sod Conseils Rech Applic Stable pharmaceutical composition containing factor VIII
US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
PL207018B1 (pl) 2002-06-21 2010-10-29 Novo Nordisk Helth Care Ag Kompozycja farmaceutyczna, sposób przygotowania stabilnego polipeptydu czynnika VII i zastosowanie polipeptydu czynnika VII
ES2287531T5 (es) † 2002-12-27 2020-06-26 Nippon Kinsen Kikai Kk Dispositivo sensor óptico para detectar características ópticas de documentos valiosos
MXPA05009914A (es) * 2003-03-18 2006-01-09 Novo Nordisk Healthcare Ag Composiciones farmaceuticas acuosas, liquidas de polipeptidos del factor vii.
US7897734B2 (en) * 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
CA2525224A1 (en) * 2003-05-23 2004-12-02 Michael Bech Jensen Protein stabilization in solution
US7485291B2 (en) 2003-06-03 2009-02-03 Cell Genesys, Inc. Compositions and methods for generating multiple polypeptides from a single vector using a virus derived peptide cleavage site, and uses thereof
CA2526120A1 (en) 2003-06-03 2005-02-24 Cell Genesys, Inc. Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
ATE547114T1 (de) 2003-06-25 2012-03-15 Novo Nordisk Healthcare Ag Flüssige zusammensetzungen von factor vii polypeptiden
EP1644030B1 (en) * 2003-07-01 2009-10-28 Novo Nordisk Health Care AG Liquid, aqueous pharmaceutical composition of factor vii polypeptides
KR20120104619A (ko) 2003-08-14 2012-09-21 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 ｖｉｉ 폴리펩티드의 액상 수성 약학적 조성물
ES2229931B1 (es) * 2003-10-03 2006-01-16 Grifols, S.A. Composicion liquida bilogicamente estable de fviii, de fvw o del complejo fviii/fvw humanos.
US20050090551A1 (en) * 2003-10-27 2005-04-28 Board Of Trustees Of Southern Illinois University Therapeutic use of methionine for the treatment or prevention of mucositis
EP1699469B1 (en) * 2003-12-03 2010-04-07 University of Rochester Recombinant factor viii having increased specific activity
CN1917861B (zh) * 2003-12-19 2012-03-21 诺和诺德医疗保健公司 因子vii多肽的稳定化固体组合物
US7422875B2 (en) * 2004-07-20 2008-09-09 Board Of Regents Of The University Of Nebraska Compositions and methods for increasing protein production
WO2007022784A2 (en) * 2005-08-26 2007-03-01 Maxygen Holdings Ltd. Liquid factor vii composition
FR2908892B1 (fr) * 2006-11-21 2009-02-20 Hyphen Biomed Soc Par Actions Procede pour le dosage chromogenique de l'activite du facteur viii:c et necessaire de dosage chromogenique de l'activite du facteur viii:c,dans les plasmas ou les fractions therapeutiques
EP2711436A1 (en) 2007-11-01 2014-03-26 University Of Rochester Recombinant factor VIII having increased stability
CN106222220A (zh) 2007-12-27 2016-12-14 百深有限责任公司 细胞培养方法
NZ593190A (en) 2008-11-07 2013-01-25 Baxter Int Factor viii formulations
GB0915481D0 (en) 2009-09-04 2009-10-07 Arecor Ltd Stable manufacture of factor V111
GB0915480D0 (en) 2009-09-04 2009-10-07 Arecor Ltd Stable formulation of factor viii
WO2012061689A2 (en) 2010-11-05 2012-05-10 Ipsen Pharma S.A.S. A new variant of antihemophilic factor viii having increased specific activity
EP4353743A3 (en) * 2011-05-13 2024-07-17 Octapharma AG A method of increasing the productivity of eucaryotic cells in the production of recombinant fviii
CA2850579A1 (en) 2011-10-18 2013-04-25 Carsten Horn Method for improving the stability of purified factor viii after reconstitution
AU2015240353A1 (en) * 2014-04-01 2016-11-17 Advantech Bioscience Farmaceutica Ltda. Stable Factor VIII formulations with low sugar-glycine
US9855319B2 (en) 2014-04-01 2018-01-02 Advantech Bioscience Farmacêutica Ltda Stabilization of factor VIII without calcium as an excipient

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988000210A1 (en) 1986-06-24 1988-01-14 Nordisk Gentofte A/S A process for producing a coagulation active complex of factor viii fragments
NZ256921A (en) 1992-10-02 1996-05-28 Pharmacia Ab Formulations of coagulation factor viii and a non-ionic surfactant and their preparation
SE9301581D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Protein formulation
AU7254894A (en) * 1993-07-23 1995-02-20 Baxter International Inc. Activated human factor viii and method of preparation
US5576291A (en) * 1993-09-13 1996-11-19 Baxter International Inc. Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency
DE69737455T2 (de) * 1996-10-11 2007-12-06 Invitrogen Corp., Carlsbad Definierte systeme zur kultivierung epithelialer zellen und anwendung derselben
US5804420A (en) * 1997-04-18 1998-09-08 Bayer Corporation Preparation of recombinant Factor VIII in a protein free medium

Also Published As

Publication number Publication date
EP1194161A1 (en) 2002-04-10
ES2252028T3 (es) 2006-05-16
AU780415B2 (en) 2005-03-17
AR024735A1 (es) 2002-10-23
ATE310533T1 (de) 2005-12-15
DE60024268D1 (de) 2005-12-29
NO330048B1 (no) 2011-02-07
DE60024268T2 (de) 2006-08-03
US6599724B1 (en) 2003-07-29
NO20020120D0 (no) 2002-01-10
AU6193300A (en) 2001-01-30
EP1194161B1 (en) 2005-11-23
CA2378751A1 (en) 2001-01-18
CY1104986T1 (el) 2009-11-04
WO2001003726A1 (en) 2001-01-18
CA2378751C (en) 2012-11-06
JP4674021B2 (ja) 2011-04-20
NZ516400A (en) 2004-02-27
JP2003504345A (ja) 2003-02-04
NO20020120L (no) 2002-02-28

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